Role of omega-3 fatty acids in obesity, metabolic syndrome, and cardiovascular diseases: a review of the evidence View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-09

AUTHORS

Silvia Lorente-Cebrián, André G. V. Costa, Santiago Navas-Carretero, María Zabala, J. Alfredo Martínez, María J. Moreno-Aliaga

ABSTRACT

The present review aims to illustrate current knowledge about the efficacy of omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFAs) in treating/preventing several metabolic pathologies. We reviewed systematically the published evidence on the effectiveness of n-3 LC-PUFAs fish consumption or n-3 LC-PUFAs supplementation on prevention/treatment of obesity, metabolic syndrome, and cardiovascular diseases. Most of the reviewed studies were randomized-controlled interventional trials, although some relevant prospective and cross-sectional studies as well as some meta-analysis were also reviewed. Supplementation with n-3 LC-PUFAs might improve some obesity-associated metabolic syndrome features such as insulin resistance, hypertension and dyslipidemia by decreasing plasma triglycerides. Moreover, the blood pressure-lowering and anti-inflammatory properties of these fatty acids and their benefits in vascular function might confer cardioprotection. However, the efficacy of n-3 LC-PUFA on reducing myocardial infarction, arrhythmia, cardiac and sudden death, or stroke is controversial. Due to the beneficial actions of n-3 LC-PUFAs, several worldwide government and health organizations have established some recommendations of n-3 LC-PUFAs intake for groups of population. In general, the recommended levels for diseases prevention are lower than those advised for particular treatments. However, more clinical trials are necessary to recommend the most effective dosages and formulas (type of n-3 LC-PUFA, EPA/DHA ratio) for specific pathologies. More... »

PAGES

633-651

References to SciGraph publications

  • 2003-02. Lack of benefit of dietary advice to men with angina: results of a controlled trial in EUROPEAN JOURNAL OF CLINICAL NUTRITION
  • 1997-08. Effect of dietary fish oil on body fat mass and basal fat oxidation in healthy adults in INTERNATIONAL JOURNAL OF OBESITY
  • 2007-08. Meta-analysis of the effects of n-3 polyunsaturated fatty acids on lipoproteins and other emerging lipid cardiovascular risk markers in patients with type 2 diabetes in DIABETOLOGIA
  • 2007-10. Randomized trial of weight-loss-diets for young adults varying in fish and fish oil content in INTERNATIONAL JOURNAL OF OBESITY
  • 2005-08. Eicosapentaenoic acid, but not oleic acid, stimulates β-oxidation in adipocytes in LIPIDS
  • 1997-07. Randomized, Double-Blind, Placebo-Controlled Trial of Fish Oil and Mustard Oil in Patients with Suspected Acute Myocardial Infarction: The Indian Experiment of Infarct Survival—4 in CARDIOVASCULAR DRUGS AND THERAPY
  • 2006-06. Effects of eicosapentaenoic acid (EPA) on adiponectin gene expression and secretion in primary cultured rat adipocytes in JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
  • 2008-12. Fish oil supplementation improves large arterial elasticity in overweight hypertensive patients in EUROPEAN JOURNAL OF CLINICAL NUTRITION
  • 2008-07. Beneficial effects of long-chain n-3 fatty acids included in an energy-restricted diet on insulin resistance in overweight and obese European young adults in DIABETOLOGIA
  • 2004-11. Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers in LIPIDS
  • 2008-10. Differential inflammatory status in rats susceptible or resistant to diet-induced obesity: effects of EPA ethyl ester treatment in EUROPEAN JOURNAL OF NUTRITION
  • 2006-10. Additive benefits of long-chain n-3 polyunsaturated fatty acids and weight-loss in the management of cardiovascular disease risk in overweight hyperinsulinaemic women in INTERNATIONAL JOURNAL OF OBESITY
  • 2006-09. Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n−3 polyunsaturated fatty acids in DIABETOLOGIA
  • 2005-11. Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce β-oxidation in white fat in DIABETOLOGIA
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s13105-013-0265-4

    DOI

    http://dx.doi.org/10.1007/s13105-013-0265-4

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1045459191

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/23794360


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