Antithrombotic therapy after percutaneous coronary intervention from the Japanese perspective View Full Text


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Article Info

DATE

2019-12-16

AUTHORS

Yuichi Saito, Yoshio Kobayashi, Kengo Tanabe, Yuji Ikari

ABSTRACT

Percutaneous coronary intervention (PCI) has become a standard-of-care procedure in patients with acute and chronic coronary syndrome. Adjunctive antithrombotic therapy following PCI is the cornerstone of pharmacological treatment to prevent ischemic events. Dual antiplatelet therapy, a combination of aspirin and a P2Y12 inhibitor, has been proven as an initial antithrombotic regimen to reduce thrombotic events in patients undergoing PCI. However, the optimal antithrombotic strategy such as appropriate duration of dual antiplatelet therapy and the safe and effective combination of oral anticoagulation with antiplatelet therapy remains under debate. Since Japanese patients have different risk profiles for both thrombotic and bleeding events compared with Western population, optimal antithrombotic regimen may be different. Recently, the evidence in this field has been rapidly evolving and the antithrombotic strategy varies widely in clinical practice. In this clinical expert consensus document, we provide an in-depth review concerning antithrombotic strategies after PCI from Japanese perspective. More... »

PAGES

19-29

References to SciGraph publications

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  • 2019-09-30. Clinical expert consensus document on standards for measurements and assessment of intravascular ultrasound from the Japanese Association of Cardiovascular Intervention and Therapeutics in CARDIOVASCULAR INTERVENTION AND THERAPEUTICS
  • 2019-07-08. Triple, dual, and single antithrombotic therapy for patients with atrial fibrillation undergoing percutaneous coronary intervention in CARDIOVASCULAR INTERVENTION AND THERAPEUTICS
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  • 2014-08-26. World Heart Federation expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI in NATURE REVIEWS CARDIOLOGY
  • 2018-03-29. CVIT expert consensus document on primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) in 2018 in CARDIOVASCULAR INTERVENTION AND THERAPEUTICS
  • 2018-07-04. Aspirin-free strategies in cardiovascular disease and cardioembolic stroke prevention in NATURE REVIEWS CARDIOLOGY
  • 2017-07-05. Comparison of platelet aggregation response in switching regimen from prasugrel to clopidogrel between CYP2C19 extensive versus non-extensive metabolizers in CARDIOVASCULAR INTERVENTION AND THERAPEUTICS
  • 2018-12-27. Clinical use of physiological lesion assessment using pressure guidewires: an expert consensus document of the Japanese Association of Cardiovascular Intervention and Therapeutics in CARDIOVASCULAR INTERVENTION AND THERAPEUTICS
  • 2019-03-07. Post-interventional adverse event risk by vascular access site among patients with acute coronary syndrome in Japan: observational analysis with a national registry J-PCI database in CARDIOVASCULAR INTERVENTION AND THERAPEUTICS
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    http://scigraph.springernature.com/pub.10.1007/s12928-019-00633-6

    DOI

    http://dx.doi.org/10.1007/s12928-019-00633-6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1123439961

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/31845096


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