Impact of shorter door-to-balloon time on prognosis of patients with STEMI—single-center analysis with a large proportion of the patients treated ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04

AUTHORS

Takeshi Yamada, Akihiko Takahashi, Yukio Mizuguchi, Sho Hashimoto, Norimasa Taniguchi, Shunsuke Nakajima, Tetsuya Hata

ABSTRACT

Several recent studies suggested that the door-to-balloon time (DTBT) for patients with ST-segment elevation myocardial infarction (STEMI) should be as short as possible, despite the existing guideline for STEMI. This study aimed to evaluate the clinical outcomes of the STEMI patient cohort having the highest proportion of patients treated with a DTBT of ≤ 30 min ever reported. We evaluated 527 consecutive patients with STEMI who underwent percutaneous coronary intervention between 2007 and 2015. The mean age was 68.0 ± 12.7 years, and the mean DTBT was 44.4 ± 33.1 min. The patients were classified into four groups according to the DTBT, and the relationship between the DTBT and clinical outcome was investigated. DTBTs were ≤ 30 min in 146 patients (27.7%), 31-60 min in 297 patients (56.4%), 61-90 min in 60 patients (11.4%), and > 90 min in 24 patients (4.6%). In-hospital mortality rates were 0.7, 5.0, 11.7, and 12.5% for DTBTs of ≤ 30, 31-60, 61-90, and > 90 min, respectively. In multivariate analysis, a DTBT ≤ 30 min (odds ratio [OR] 0.11, 95% confidence interval [CI] 0.01-0.91, p = 0.041), shock on arrival (OR 2.74, 95% CI 1.02-7.37, p = 0.046), and blood transfusion (OR 49.60, 95% CI 13.90-177.00, p < 0.001) were the independent predictors of in-hospital mortality. Patients with STEMI treated with a DTBT ≤ 30 min showed significantly better clinical outcomes than those treated with a DTBT > 30 min. More... »

PAGES

97-104

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12928-018-0521-1

DOI

http://dx.doi.org/10.1007/s12928-018-0521-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1103845699

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29736670


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