Comparison of Everolimus- versus Sirolimus-eluting stents in the provisional Bifurcation stenting guided by intravascular ultrasound: mid-term results of the J-REVERSE ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2015-05-22

AUTHORS

Yoshinobu Murasato, Yoshihisa Kinoshita, Masahiro Yamawaki, Toshiro Shinke, Hiromasa Otake, Yoshihiro Takeda, Kenichi Fujii, Shin-ichiro Yamada, Yoshihisa Shimada, Takehiro Yamashita, Kazuhiko Yumoto

ABSTRACT

This study aimed at comparing the mid-term clinical outcome of everolimus-eluting (EES) with sirolimus-eluting (SES) stents in the provisional bifurcation stenting guided by intravascular ultrasound (IVUS). We compared the clinical outcome up to 9-month follow-up results of the prospective J-REVERSE registry of 300 non-left main bifurcation lesions in 298 patients treated with EES (n = 240) and SES (n = 60). The SB dilation with the kissing balloon technique (KBT) was performed in 54 %. The patient and lesion characteristics of the groups were similar. The incidences of SB dissections, occlusions, stenting, and slow flow were similar. A greater luminal volume gain was achieved in the proximal MV after KBT compared in non-KBT treated lesions in the EES group (7.9 ± 2.4 versus 7.0 ± 2.0 mm3/mm, p = 0.002), though not in the SES group. The SB diameter stenosis in the non-KBT treatment at 9 months was greater than the KBT in both groups. The incidence of target lesion revascularisation (TLR) was 5.0 % in the EES versus 8.3 % in the SES group (p = 0.35), and the incidence of major adverse cardiac events, including TLR, myocardial infarction, stent thrombosis, and death was 5.4 % in the EES versus 11.7 % in the SES group (p = 0.15). IVUS-guided provisional stenting with EES achieved a greater luminal gain after than without KBT, and similar clinical outcomes as with SES up to 9-month follow-up. More... »

PAGES

1-12

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12928-015-0336-2

DOI

http://dx.doi.org/10.1007/s12928-015-0336-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011020643

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/25998890


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