Effect of Molecular Characteristics and Morphology on Mechanical Performance and Biocompatibility of PLA-Based Spongious Scaffolds View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-12

AUTHORS

T. E. Grigoriev, T. B. Bukharova, A. V. Vasilyev, G. E. Leonov, Y. D. Zagoskin, V. S. Kuznetsova, V. I. Gomzyak, D. I. Salikhova, E. V. Galitsyna, O. V. Makhnach, K. V. Tokaev, S. N. Chvalun, D. V. Goldshtein, A. A. Kulakov, M. A. Paltsev

ABSTRACT

The effect of molecular characteristics and morphology on mechanical performance and biocompatibility of PLA-based spongious scaffolds was studied. PLLA and PDLLA with different molecular weight were studied. It was shown that the structure and the mechanical properties of PLA sponges slightly depend on the molecular mass of the polymer. In the contrary, porosity of the sponge-like material has great effect on its mechanical properties. Biocompatibility tests showed that PLLA provide better matrix behavior compared to PDLLA for the stem cells from human exfoliated deciduous teeth. More... »

PAGES

977-983

References to SciGraph publications

  • 2011-11. Crystallinity assessment and in vitro cytotoxicity of polylactide scaffolds for biomedical applications in JOURNAL OF MATERIALS SCIENCE: MATERIALS IN MEDICINE
  • 2017-09. New “old” polylactides for tissue engineering constructions in INORGANIC MATERIALS: APPLIED RESEARCH
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12668-018-0557-9

    DOI

    http://dx.doi.org/10.1007/s12668-018-0557-9

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1106158868


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