Efficacy and safety of sofosbuvir-based regimens in chronic hepatitis C patients on dialysis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-03-09

AUTHORS

Narendra S Choudhary, Amit Kumar, Vijay Bodh, Shyam Bihari Bansal, Reetesh Sharma, Manish Jain, Sanjiv Saigal, Neeraj Saraf

ABSTRACT

IntroductionPatients with end-stage renal disease (ESRD) have poor treatment tolerance and outcome to interferon-based regimens. Sofosbuvir-based regimens have improved treatment success in chronic hepatitis C. There is limited data in ESRD patients as sofosbuvir is excreted by the kidney. Several small studies have shown good results.MethodsSixteen consecutive patients of ESRD (on dialysis) and chronic hepatitis C were treated with sofosbuvir-based regimens as they were prospective kidney transplantation recipients, at a tertiary care center in north India. Sofosbuvir was given 400 mg on alternate days. Data is shown as number, mean (SD), and median (range).ResultsSixteen patients (12 males) aged 45±12 years received sofosbuvir-based treatment. These patients were on hemodialysis from 10 (2–48) months. Eleven of these patients had genotype 1, four had genotype 3, and one had genotype 4 infection; baseline RNA was 7 (5–8) log. The following treatment regimens were used: sofosbuvir, ribavirin, and low dose peginterferon (n = 8; 6 genotype 1 and one each had genotype 3 and 4); sofosbuvir and daclatasvir (n = 7); sofosbuvir, ribavirin, and daclatasvir (n = 1). Ten patients achieved end of treatment response and 8 (80%) of these achieved sustained virological response at 12 weeks (SVR12); six are on treatment. Two patients with genotype one (including one with cirrhosis) had relapse. Seven patients needed blood transfusion; interferon was stopped in one due to thrombocytopenia. Fatigue was present in 4 patients.ConclusionSofosbuvir-based regimens can be used in ESRD patients on dialysis with good efficacy. More... »

PAGES

113-116

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12664-017-0735-7

DOI

http://dx.doi.org/10.1007/s12664-017-0735-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1084036163

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28281085


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antiviral Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Administration Schedule", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Therapy, Combination", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genotype", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepacivirus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hepatitis C, Chronic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney Failure, Chronic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Renal Dialysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sofosbuvir", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Medanta Liver Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India", 
          "id": "http://www.grid.ac/institutes/grid.429252.a", 
          "name": [
            "Medanta Liver Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Choudhary", 
        "givenName": "Narendra S", 
        "id": "sg:person.0723456266.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723456266.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medanta Liver Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India", 
          "id": "http://www.grid.ac/institutes/grid.429252.a", 
          "name": [
            "Medanta Liver Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kumar", 
        "givenName": "Amit", 
        "id": "sg:person.01177502720.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01177502720.92"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medanta Liver Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India", 
          "id": "http://www.grid.ac/institutes/grid.429252.a", 
          "name": [
            "Medanta Liver Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bodh", 
        "givenName": "Vijay", 
        "id": "sg:person.0713420212.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713420212.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medanta Kidney Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India", 
          "id": "http://www.grid.ac/institutes/grid.429252.a", 
          "name": [
            "Medanta Kidney Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bansal", 
        "givenName": "Shyam Bihari", 
        "id": "sg:person.01043653300.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043653300.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medanta Kidney Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India", 
          "id": "http://www.grid.ac/institutes/grid.429252.a", 
          "name": [
            "Medanta Kidney Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sharma", 
        "givenName": "Reetesh", 
        "id": "sg:person.07646447262.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07646447262.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medanta Kidney Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India", 
          "id": "http://www.grid.ac/institutes/grid.429252.a", 
          "name": [
            "Medanta Kidney Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jain", 
        "givenName": "Manish", 
        "id": "sg:person.01274330300.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274330300.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medanta Liver Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India", 
          "id": "http://www.grid.ac/institutes/grid.429252.a", 
          "name": [
            "Medanta Liver Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saigal", 
        "givenName": "Sanjiv", 
        "id": "sg:person.01354041343.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354041343.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medanta Liver Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India", 
          "id": "http://www.grid.ac/institutes/grid.429252.a", 
          "name": [
            "Medanta Liver Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saraf", 
        "givenName": "Neeraj", 
        "id": "sg:person.01037704666.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01037704666.35"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s40264-016-0420-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010767592", 
          "https://doi.org/10.1007/s40264-016-0420-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrneph.2015.5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028735473", 
          "https://doi.org/10.1038/nrneph.2015.5"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-03-09", 
    "datePublishedReg": "2017-03-09", 
    "description": "IntroductionPatients with end-stage renal disease (ESRD) have poor treatment tolerance and outcome to interferon-based regimens. Sofosbuvir-based regimens have improved treatment success in chronic hepatitis C. There is limited data in ESRD patients as sofosbuvir is excreted by the kidney. Several small studies have shown good results.MethodsSixteen consecutive patients of ESRD (on dialysis) and chronic hepatitis C were treated with sofosbuvir-based regimens as they were prospective kidney transplantation recipients, at a tertiary care center in north India. Sofosbuvir was given 400\u00a0mg on alternate days. Data is shown as number, mean (SD), and median (range).ResultsSixteen patients (12 males) aged 45\u00b112 years received sofosbuvir-based treatment. These patients were on hemodialysis from 10 (2\u201348) months. Eleven of these patients had genotype 1, four had genotype 3, and one had genotype 4 infection; baseline RNA was 7 (5\u20138) log. The following treatment regimens were used: sofosbuvir, ribavirin, and low dose peginterferon (n\u00a0=\u00a08; 6 genotype 1 and one each had genotype 3 and 4); sofosbuvir and daclatasvir (n\u00a0=\u00a07); sofosbuvir, ribavirin, and daclatasvir (n\u00a0=\u00a01). Ten patients achieved end of treatment response and 8 (80%) of these achieved sustained virological response at 12\u00a0weeks (SVR12); six are on treatment. Two patients with genotype one (including one with cirrhosis) had relapse. Seven patients needed blood transfusion; interferon was stopped in one due to thrombocytopenia. Fatigue was present in 4 patients.ConclusionSofosbuvir-based regimens can be used in ESRD patients on dialysis with good efficacy.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s12664-017-0735-7", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1094828", 
        "issn": [
          "0254-8860", 
          "0975-0711"
        ], 
        "name": "Indian Journal of Gastroenterology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "36"
      }
    ], 
    "keywords": [
      "end-stage renal disease", 
      "sofosbuvir-based regimens", 
      "ESRD patients", 
      "chronic hepatitis C patients", 
      "poor treatment tolerance", 
      "genotype 4 infection", 
      "low-dose peginterferon", 
      "interferon-based regimens", 
      "chronic hepatitis C.", 
      "chronic hepatitis C", 
      "sustained virological response", 
      "hepatitis C patients", 
      "kidney transplantation recipients", 
      "tertiary care center", 
      "MethodsSixteen consecutive patients", 
      "ResultsSixteen patients", 
      "baseline RNA", 
      "virological response", 
      "hepatitis C", 
      "C patients", 
      "treatment tolerance", 
      "hepatitis C.", 
      "transplantation recipients", 
      "renal disease", 
      "consecutive patients", 
      "blood transfusion", 
      "treatment regimens", 
      "treatment success", 
      "care center", 
      "genotype 3", 
      "genotype 1", 
      "treatment response", 
      "regimens", 
      "patients", 
      "small study", 
      "sofosbuvir", 
      "better efficacy", 
      "alternate days", 
      "North India", 
      "ribavirin", 
      "daclatasvir", 
      "dialysis", 
      "efficacy", 
      "treatment", 
      "genotype one", 
      "peginterferon", 
      "IntroductionPatients", 
      "transfusion", 
      "thrombocytopenia", 
      "hemodialysis", 
      "relapse", 
      "interferon", 
      "kidney", 
      "infection", 
      "disease", 
      "recipients", 
      "weeks", 
      "months", 
      "response", 
      "median", 
      "outcomes", 
      "days", 
      "safety", 
      "fatigue", 
      "years", 
      "RNA", 
      "better results", 
      "data", 
      "center", 
      "study", 
      "C.", 
      "tolerance", 
      "number", 
      "India", 
      "success", 
      "end", 
      "results", 
      "logs", 
      "one"
    ], 
    "name": "Efficacy and safety of sofosbuvir-based regimens in chronic hepatitis C patients on dialysis", 
    "pagination": "113-116", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1084036163"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12664-017-0735-7"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28281085"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12664-017-0735-7", 
      "https://app.dimensions.ai/details/publication/pub.1084036163"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-12-01T06:36", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/article/article_737.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s12664-017-0735-7"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12664-017-0735-7'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12664-017-0735-7'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12664-017-0735-7'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12664-017-0735-7'


 

This table displays all metadata directly associated to this object as RDF triples.

259 TRIPLES      21 PREDICATES      121 URIs      111 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12664-017-0735-7 schema:about N1b4c43b410784e15b728c904ca96c017
2 N21d933c02efb425d99d001a1e753c901
3 N3a9978f07b554e899bdbd9383af919cb
4 N58f90f32fae3441692591d140fef1faa
5 N86d250ecbcef4c5592c2b4c752b8e3f0
6 N8781845018404a6c96ec373a37a27ce3
7 N8ac9e040183e41d59dda98c0126b78ac
8 N90dd1f42f4324d87b5a1486d9314b8ea
9 N9cf7c6b4deeb4b47a54c96d642303c1d
10 Na2c0c37803fe4ce5ad78ab3ed465c220
11 Na7f25f6f87e54a51a9c64dc58fb1f481
12 Nc36f4ee630ac44b0b0bb95c4583e0c82
13 Nc40f3a82f8a249ccaf269533d3b4ec8f
14 Ndc64521ec769457aa14cc4c2469d72f0
15 Nf96589cdd1ee401dad3d0f6d5eca20e4
16 anzsrc-for:11
17 anzsrc-for:1103
18 schema:author Nd3a75cef33a6433e80372f2f4c0609b8
19 schema:citation sg:pub.10.1007/s40264-016-0420-2
20 sg:pub.10.1038/nrneph.2015.5
21 schema:datePublished 2017-03-09
22 schema:datePublishedReg 2017-03-09
23 schema:description IntroductionPatients with end-stage renal disease (ESRD) have poor treatment tolerance and outcome to interferon-based regimens. Sofosbuvir-based regimens have improved treatment success in chronic hepatitis C. There is limited data in ESRD patients as sofosbuvir is excreted by the kidney. Several small studies have shown good results.MethodsSixteen consecutive patients of ESRD (on dialysis) and chronic hepatitis C were treated with sofosbuvir-based regimens as they were prospective kidney transplantation recipients, at a tertiary care center in north India. Sofosbuvir was given 400 mg on alternate days. Data is shown as number, mean (SD), and median (range).ResultsSixteen patients (12 males) aged 45±12 years received sofosbuvir-based treatment. These patients were on hemodialysis from 10 (2–48) months. Eleven of these patients had genotype 1, four had genotype 3, and one had genotype 4 infection; baseline RNA was 7 (5–8) log. The following treatment regimens were used: sofosbuvir, ribavirin, and low dose peginterferon (n = 8; 6 genotype 1 and one each had genotype 3 and 4); sofosbuvir and daclatasvir (n = 7); sofosbuvir, ribavirin, and daclatasvir (n = 1). Ten patients achieved end of treatment response and 8 (80%) of these achieved sustained virological response at 12 weeks (SVR12); six are on treatment. Two patients with genotype one (including one with cirrhosis) had relapse. Seven patients needed blood transfusion; interferon was stopped in one due to thrombocytopenia. Fatigue was present in 4 patients.ConclusionSofosbuvir-based regimens can be used in ESRD patients on dialysis with good efficacy.
24 schema:genre article
25 schema:isAccessibleForFree false
26 schema:isPartOf N7dd803b9b2764b9badce6c6764d7308a
27 Ncf9def86be3e487688b07129bbcc870a
28 sg:journal.1094828
29 schema:keywords C patients
30 C.
31 ESRD patients
32 India
33 IntroductionPatients
34 MethodsSixteen consecutive patients
35 North India
36 RNA
37 ResultsSixteen patients
38 alternate days
39 baseline RNA
40 better efficacy
41 better results
42 blood transfusion
43 care center
44 center
45 chronic hepatitis C
46 chronic hepatitis C patients
47 chronic hepatitis C.
48 consecutive patients
49 daclatasvir
50 data
51 days
52 dialysis
53 disease
54 efficacy
55 end
56 end-stage renal disease
57 fatigue
58 genotype 1
59 genotype 3
60 genotype 4 infection
61 genotype one
62 hemodialysis
63 hepatitis C
64 hepatitis C patients
65 hepatitis C.
66 infection
67 interferon
68 interferon-based regimens
69 kidney
70 kidney transplantation recipients
71 logs
72 low-dose peginterferon
73 median
74 months
75 number
76 one
77 outcomes
78 patients
79 peginterferon
80 poor treatment tolerance
81 recipients
82 regimens
83 relapse
84 renal disease
85 response
86 results
87 ribavirin
88 safety
89 small study
90 sofosbuvir
91 sofosbuvir-based regimens
92 study
93 success
94 sustained virological response
95 tertiary care center
96 thrombocytopenia
97 tolerance
98 transfusion
99 transplantation recipients
100 treatment
101 treatment regimens
102 treatment response
103 treatment success
104 treatment tolerance
105 virological response
106 weeks
107 years
108 schema:name Efficacy and safety of sofosbuvir-based regimens in chronic hepatitis C patients on dialysis
109 schema:pagination 113-116
110 schema:productId N0df290bcb72049039803fb455ca93204
111 N1ebf698c314940e5baa7447bad9f5ae4
112 Ne18f9332f9934ca7b7f3a1d510888643
113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084036163
114 https://doi.org/10.1007/s12664-017-0735-7
115 schema:sdDatePublished 2022-12-01T06:36
116 schema:sdLicense https://scigraph.springernature.com/explorer/license/
117 schema:sdPublisher Naa57728daecd48f4bab38c222f67f6dc
118 schema:url https://doi.org/10.1007/s12664-017-0735-7
119 sgo:license sg:explorer/license/
120 sgo:sdDataset articles
121 rdf:type schema:ScholarlyArticle
122 N08f57be5c5914e728c6edfedec2311e4 rdf:first sg:person.01177502720.92
123 rdf:rest N5f2f1a5902dd41cd8b9c4e8ee82d45a0
124 N0df290bcb72049039803fb455ca93204 schema:name doi
125 schema:value 10.1007/s12664-017-0735-7
126 rdf:type schema:PropertyValue
127 N1b4c43b410784e15b728c904ca96c017 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Sofosbuvir
129 rdf:type schema:DefinedTerm
130 N1ebf698c314940e5baa7447bad9f5ae4 schema:name pubmed_id
131 schema:value 28281085
132 rdf:type schema:PropertyValue
133 N21d933c02efb425d99d001a1e753c901 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Female
135 rdf:type schema:DefinedTerm
136 N3a9978f07b554e899bdbd9383af919cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Treatment Outcome
138 rdf:type schema:DefinedTerm
139 N5111d92037ea47c397eff5cd84d82fa5 rdf:first sg:person.07646447262.42
140 rdf:rest Naaeef1bb02b64e81991773f7294497f5
141 N58f90f32fae3441692591d140fef1faa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Renal Dialysis
143 rdf:type schema:DefinedTerm
144 N5f2f1a5902dd41cd8b9c4e8ee82d45a0 rdf:first sg:person.0713420212.19
145 rdf:rest Nace2ff657039402da64be9a0b7d6be2a
146 N6e2ff134d12c4ef2828461c4ea4376de rdf:first sg:person.01354041343.18
147 rdf:rest N8ff7a501b3eb49dc8f190cb37983de23
148 N7dd803b9b2764b9badce6c6764d7308a schema:volumeNumber 36
149 rdf:type schema:PublicationVolume
150 N86d250ecbcef4c5592c2b4c752b8e3f0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Kidney Failure, Chronic
152 rdf:type schema:DefinedTerm
153 N8781845018404a6c96ec373a37a27ce3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Hepatitis C, Chronic
155 rdf:type schema:DefinedTerm
156 N8ac9e040183e41d59dda98c0126b78ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Antiviral Agents
158 rdf:type schema:DefinedTerm
159 N8ff7a501b3eb49dc8f190cb37983de23 rdf:first sg:person.01037704666.35
160 rdf:rest rdf:nil
161 N90dd1f42f4324d87b5a1486d9314b8ea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Hepacivirus
163 rdf:type schema:DefinedTerm
164 N9cf7c6b4deeb4b47a54c96d642303c1d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Middle Aged
166 rdf:type schema:DefinedTerm
167 Na2c0c37803fe4ce5ad78ab3ed465c220 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Humans
169 rdf:type schema:DefinedTerm
170 Na7f25f6f87e54a51a9c64dc58fb1f481 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Drug Administration Schedule
172 rdf:type schema:DefinedTerm
173 Naa57728daecd48f4bab38c222f67f6dc schema:name Springer Nature - SN SciGraph project
174 rdf:type schema:Organization
175 Naaeef1bb02b64e81991773f7294497f5 rdf:first sg:person.01274330300.65
176 rdf:rest N6e2ff134d12c4ef2828461c4ea4376de
177 Nace2ff657039402da64be9a0b7d6be2a rdf:first sg:person.01043653300.19
178 rdf:rest N5111d92037ea47c397eff5cd84d82fa5
179 Nc36f4ee630ac44b0b0bb95c4583e0c82 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
180 schema:name Drug Therapy, Combination
181 rdf:type schema:DefinedTerm
182 Nc40f3a82f8a249ccaf269533d3b4ec8f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Adult
184 rdf:type schema:DefinedTerm
185 Ncf9def86be3e487688b07129bbcc870a schema:issueNumber 2
186 rdf:type schema:PublicationIssue
187 Nd3a75cef33a6433e80372f2f4c0609b8 rdf:first sg:person.0723456266.35
188 rdf:rest N08f57be5c5914e728c6edfedec2311e4
189 Ndc64521ec769457aa14cc4c2469d72f0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
190 schema:name Male
191 rdf:type schema:DefinedTerm
192 Ne18f9332f9934ca7b7f3a1d510888643 schema:name dimensions_id
193 schema:value pub.1084036163
194 rdf:type schema:PropertyValue
195 Nf96589cdd1ee401dad3d0f6d5eca20e4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
196 schema:name Genotype
197 rdf:type schema:DefinedTerm
198 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
199 schema:name Medical and Health Sciences
200 rdf:type schema:DefinedTerm
201 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
202 schema:name Clinical Sciences
203 rdf:type schema:DefinedTerm
204 sg:journal.1094828 schema:issn 0254-8860
205 0975-0711
206 schema:name Indian Journal of Gastroenterology
207 schema:publisher Springer Nature
208 rdf:type schema:Periodical
209 sg:person.01037704666.35 schema:affiliation grid-institutes:grid.429252.a
210 schema:familyName Saraf
211 schema:givenName Neeraj
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01037704666.35
213 rdf:type schema:Person
214 sg:person.01043653300.19 schema:affiliation grid-institutes:grid.429252.a
215 schema:familyName Bansal
216 schema:givenName Shyam Bihari
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043653300.19
218 rdf:type schema:Person
219 sg:person.01177502720.92 schema:affiliation grid-institutes:grid.429252.a
220 schema:familyName Kumar
221 schema:givenName Amit
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01177502720.92
223 rdf:type schema:Person
224 sg:person.01274330300.65 schema:affiliation grid-institutes:grid.429252.a
225 schema:familyName Jain
226 schema:givenName Manish
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274330300.65
228 rdf:type schema:Person
229 sg:person.01354041343.18 schema:affiliation grid-institutes:grid.429252.a
230 schema:familyName Saigal
231 schema:givenName Sanjiv
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354041343.18
233 rdf:type schema:Person
234 sg:person.0713420212.19 schema:affiliation grid-institutes:grid.429252.a
235 schema:familyName Bodh
236 schema:givenName Vijay
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713420212.19
238 rdf:type schema:Person
239 sg:person.0723456266.35 schema:affiliation grid-institutes:grid.429252.a
240 schema:familyName Choudhary
241 schema:givenName Narendra S
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723456266.35
243 rdf:type schema:Person
244 sg:person.07646447262.42 schema:affiliation grid-institutes:grid.429252.a
245 schema:familyName Sharma
246 schema:givenName Reetesh
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07646447262.42
248 rdf:type schema:Person
249 sg:pub.10.1007/s40264-016-0420-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010767592
250 https://doi.org/10.1007/s40264-016-0420-2
251 rdf:type schema:CreativeWork
252 sg:pub.10.1038/nrneph.2015.5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028735473
253 https://doi.org/10.1038/nrneph.2015.5
254 rdf:type schema:CreativeWork
255 grid-institutes:grid.429252.a schema:alternateName Medanta Kidney Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India
256 Medanta Liver Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India
257 schema:name Medanta Kidney Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India
258 Medanta Liver Institute, Medanta The Medicity, 122 018, Gurgaon, Haryana, India
259 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...