Correlations Between Gene Expression and Mercury Levels in Blood of Boys With and Without Autism View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-01

AUTHORS

Boryana Stamova, Peter G. Green, Yingfang Tian, Irva Hertz-Picciotto, Isaac N. Pessah, Robin Hansen, Xiaowei Yang, Jennifer Teng, Jeffrey P. Gregg, Paul Ashwood, Judy Van de Water, Frank R. Sharp

ABSTRACT

Gene expression in blood was correlated with mercury levels in blood of 2- to 5-year-old boys with autism (AU) compared to age-matched typically developing (TD) control boys. This was done to address the possibility that the two groups might metabolize toxicants, such as mercury, differently. RNA was isolated from blood and gene expression assessed on whole genome Affymetrix Human U133 expression microarrays. Mercury levels were measured using an inductively coupled plasma mass spectrometer. Analysis of covariance (ANCOVA) was performed and partial correlations between gene expression and mercury levels were calculated, after correcting for age and batch effects. To reduce false positives, only genes shared by the ANCOVA models were analyzed. Of the 26 genes that correlated with mercury levels in both AU and TD boys, 11 were significantly different between the groups (P(Diagnosis*Mercury) ≤ 0.05). The expression of a large number of genes (n = 316) correlated with mercury levels in TD but not in AU boys (P ≤ 0.05), the most represented biological functions being cell death and cell morphology. Expression of 189 genes correlated with mercury levels in AU but not in TD boys (P ≤ 0.05), the most represented biological functions being cell morphology, amino acid metabolism, and antigen presentation. These data and those in our companion study on correlation of gene expression and lead levels show that AU and TD children display different correlations between transcript levels and low levels of mercury and lead. These findings might suggest different genetic transcriptional programs associated with mercury in AU compared to TD children. More... »

PAGES

31-48

References to SciGraph publications

  • 1994-10. Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 1996-05. Immunogenetic studies in autism and related disorders in JOURNAL OF MOLECULAR NEUROSCIENCE
  • 2011-01. Correlations of Gene Expression with Blood Lead Levels in Children with Autism Compared to Typically Developing Controls in NEUROTOXICITY RESEARCH
  • 2004-06. Preprocessing of oligonucleotide array data in NATURE BIOTECHNOLOGY
  • 1997-10. Diagnosing Autism: Analyses of Data from the Autism Diagnostic Interview in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2001-01. Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration in NATURE
  • 1997-04. Brief Report: Immunoglobulin a Deficiency in a Subset of Autistic Subjects in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2000-01. Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein in NATURE
  • 1994-08. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways in NATURE
  • 1999-11. Activators and target genes of Rel/NF-κB transcription factors in ONCOGENE
  • 1996-08. Brief report: Dysregulated immune system in children with autism: Beneficial effects of intravenous immune globulin on autistic characteristics in JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
  • 2008-01. The BCL-2 protein family: opposing activities that mediate cell death in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12640-009-9137-7

    DOI

    http://dx.doi.org/10.1007/s12640-009-9137-7

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1045928930

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19937285


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