Cohorte MecoExpo : utilisation du méconium pour estimer l’exposition in utero aux pesticides des nouveau-nés en Picardie View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-06

AUTHORS

P. Tourneux, F. Mayhoub, E. Haraux, C. Deguines, T. Berton, F. Lestremeau, J. Gondry, V. Bach, K. Chardon

ABSTRACT

L’étude MecoExpo menée en Picardie, région agricole utilisatrice de pesticides, visait à mettre en relation l’exposition parentale et l’imprégnation foetale aux pesticides avec les paramètres cliniques du développement fœtal relevés à la naissance. L’exposition parentale aux pesticides a été évaluée par un questionnaire et l’imprégnation foetale aux pesticides, pour la première fois en France, par un dosage dans le méconium. Neuf cent quatre-vingt-treize couples mère-enfant ont été inclus. Une association entre exposition professionnelle maternelle aux pesticides et augmentation du risque de restriction de croissance fœtale pour le poids de naissance a été observée. Une augmentation du risque de prématurité chez les enfants issus de père travaillant dans un secteur exposé aux pesticides a également été relevée. Quatre-vingt-cinq pour cent des nouveau-nés présentaient au moins un des pesticides recherchés dans leur méconium. Les pesticides observés le plus fréquemment sont les métabolites des organophosphorés et ceux des carbamates, deux grandes familles d’insecticides dispersés sur les grandes cultures. Des associations entre l’exposition professionnelle maternelle et paternelle et les paramètres cliniques à la naissance ont été observées. La recherche des pesticides a été réalisée pour la première fois en France dans le méconium de nouveau-nés. More... »

PAGES

122-133

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12611-014-0277-5

DOI

http://dx.doi.org/10.1007/s12611-014-0277-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1035027152


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25 schema:description L’étude MecoExpo menée en Picardie, région agricole utilisatrice de pesticides, visait à mettre en relation l’exposition parentale et l’imprégnation foetale aux pesticides avec les paramètres cliniques du développement fœtal relevés à la naissance. L’exposition parentale aux pesticides a été évaluée par un questionnaire et l’imprégnation foetale aux pesticides, pour la première fois en France, par un dosage dans le méconium. Neuf cent quatre-vingt-treize couples mère-enfant ont été inclus. Une association entre exposition professionnelle maternelle aux pesticides et augmentation du risque de restriction de croissance fœtale pour le poids de naissance a été observée. Une augmentation du risque de prématurité chez les enfants issus de père travaillant dans un secteur exposé aux pesticides a également été relevée. Quatre-vingt-cinq pour cent des nouveau-nés présentaient au moins un des pesticides recherchés dans leur méconium. Les pesticides observés le plus fréquemment sont les métabolites des organophosphorés et ceux des carbamates, deux grandes familles d’insecticides dispersés sur les grandes cultures. Des associations entre l’exposition professionnelle maternelle et paternelle et les paramètres cliniques à la naissance ont été observées. La recherche des pesticides a été réalisée pour la première fois en France dans le méconium de nouveau-nés.
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