Phase Angle and Frailty are Important Prognostic Factors in Critically Ill Medical Patients: A Prospective Cohort Study View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2020-10-12

AUTHORS

S. J. Ko, J. Cho, S. M. Choi, Y. S. Park, C.-H. Lee, S.-M. Lee, C.-G. Yoo, Y. W. Kim, Jinwoo Lee

ABSTRACT

ObjectivesTo investigate whether phase angle (PhA) measured by bioelectrical impedance analysis (BIA) and frailty are associated with the outcomes of critical illnesses.DesignA single-center prospective cohort study.SettingMedical intensive care unit (ICU) in Seoul National University Hospital, Seoul, Republic of Korea.Participants97 patients who were admitted to the medical ICU.MeasurementsOn admission, PhA was measured by BIA, and frailty was assessed by the Korean Modified Barthel Index (KMBI) scoring system. Patients were classified according to PhA and KMBI scores, and their impact on the outcomes of critical illnesses was evaluated.ResultsThe patients’ mean age was 62.4 ± 16.4 years, and 56 of the patients (57.7%) were men. Having a high PhA above 3.5 at the time of ICU admission was associated with lower in-hospital mortality (adjusted OR 0.42, p =.042), and a shorter duration of ICU stay (5.6 days vs. 9.8 days, p =.016) compared to those with a low PhA. Other indices measured by BIA were not significantly associated with outcomes of critical illnesses. Frailty (KMBI > 60) was associated with more mechanical ventilation days (2.3 days vs. 7.1 days; p =.018).ConclusionBoth PhA and frailty are important prognostic factors predicting the outcomes of critical illnesses. Low PhA scores were associated with increased mortality and a longer duration of ICU stay, and frailty was associated with more mechanical ventilation days. More... »

PAGES

218-223

References to SciGraph publications

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  • 2019-10-08. Frailty and invasive mechanical ventilation: association with outcomes, extubation failure, and tracheostomy in INTENSIVE CARE MEDICINE
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  • 2020-03-13. Mortality prediction by SOFA score in ICU-patients after cardiac surgery; comparison with traditional prognostic–models in BMC ANESTHESIOLOGY
  • 2011-02-04. Frailty in the critically ill: a novel concept in CRITICAL CARE
  • 2017-09-21. The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years) in INTENSIVE CARE MEDICINE
  • 2008-08-27. Bioelectrical impedance phase angle as a prognostic indicator in breast cancer in BMC CANCER
  • 2016-08-11. Fat-free mass at admission predicts 28-day mortality in intensive care unit patients: the international prospective observational study Phase Angle Project in INTENSIVE CARE MEDICINE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12603-020-1487-0

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    http://dx.doi.org/10.1007/s12603-020-1487-0

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/33491037


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