Differential effects of type 2 diabetes on brain glycometabolism in rats: focus on glycogen and monocarboxylate transporter 2 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-01

AUTHORS

Takeru Shima, Subrina Jesmin, Takashi Matsui, Mariko Soya, Hideaki Soya

ABSTRACT

Astrocyte-neuron lactate shuttle (ANLS) is a pathway that supplies glycogen-derived lactate to active neurons via monocarboxylate transporter 2 (MCT2), and is important for maintaining brain functions. Our study revealed alterations of ANLS with hippocampal hyper-glycogen levels and downregulated MCT2 protein levels underlying hippocampal dysfunctions as a complication in type 2 diabetic (T2DM) animals. Since T2DM rats exhibit brain dysfunctions involving several brain regions, we examined whether there might also be T2DM effects on ANLS's disturbances in other brain loci. OLETF rats exhibited significantly higher glycogen levels in the hippocampus, hypothalamus, and cerebral cortex than did LETO rats. MCT2 protein levels in OLETF rats decreased significantly in the hippocampus and hypothalamus compared to their controls, but a significant correlation with glycogen levels was only observed in the hippocampus. This suggests that the hippocampus may be more vulnerable to T2DM compared to other brain regions in the context of ANLS disruption. More... »

PAGES

69-75

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12576-016-0508-6

DOI

http://dx.doi.org/10.1007/s12576-016-0508-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026669073

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27987117


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Astrocytes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cerebral Cortex", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diabetes Mellitus, Type 2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glycogen", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hippocampus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Monocarboxylic Acid Transporters", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neurons", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Inbred OLETF", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Tsukuba", 
          "id": "https://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Laboratory of Exercise Biochemistry and Neuroendocrinology, Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennoudai, 305-8574, Tsukuba, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shima", 
        "givenName": "Takeru", 
        "id": "sg:person.010003120601.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010003120601.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tsukuba", 
          "id": "https://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Laboratory of Exercise Biochemistry and Neuroendocrinology, Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennoudai, 305-8574, Tsukuba, Ibaraki, Japan", 
            "Department of Sports Neuroscience, Advanced Research Initiative for Human High Performance (ARIHHP), University of Tsukuba, 1-1-1 Tennoudai, 305-8574, Tsukuba, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jesmin", 
        "givenName": "Subrina", 
        "id": "sg:person.01175270476.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175270476.03"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tsukuba", 
          "id": "https://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Laboratory of Exercise Biochemistry and Neuroendocrinology, Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennoudai, 305-8574, Tsukuba, Ibaraki, Japan", 
            "Department of Sports Neuroscience, Advanced Research Initiative for Human High Performance (ARIHHP), University of Tsukuba, 1-1-1 Tennoudai, 305-8574, Tsukuba, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsui", 
        "givenName": "Takashi", 
        "id": "sg:person.01033617617.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033617617.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tsukuba", 
          "id": "https://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Laboratory of Exercise Biochemistry and Neuroendocrinology, Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennoudai, 305-8574, Tsukuba, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Soya", 
        "givenName": "Mariko", 
        "id": "sg:person.012771022601.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012771022601.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tsukuba", 
          "id": "https://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Laboratory of Exercise Biochemistry and Neuroendocrinology, Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennoudai, 305-8574, Tsukuba, Ibaraki, Japan", 
            "Department of Sports Neuroscience, Advanced Research Initiative for Human High Performance (ARIHHP), University of Tsukuba, 1-1-1 Tennoudai, 305-8574, Tsukuba, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Soya", 
        "givenName": "Hideaki", 
        "id": "sg:person.0603002311.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603002311.15"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/ncomms4284", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000968027", 
          "https://doi.org/10.1038/ncomms4284"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpendo.00525.2010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002358342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/jcbfm.2011.149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002617488"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/jcbfm.2011.149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002617488"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.physbeh.2005.10.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004451669"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-2697(74)90248-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008331910"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/157339909788166846", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011504466"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.brainres.2012.08.056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011527505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neulet.2016.09.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012008008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0082991", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014319070"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11064-015-1594-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019080237", 
          "https://doi.org/10.1007/s11064-015-1594-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.2005.03168.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024544157"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.2005.03168.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024544157"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2011.02.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028061932"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0896-6273(00)81084-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031361052"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10072-015-2087-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038296725", 
          "https://doi.org/10.1007/s10072-015-2087-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00125-016-4164-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042067335", 
          "https://doi.org/10.1007/s00125-016-4164-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00125-016-4164-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042067335", 
          "https://doi.org/10.1007/s00125-016-4164-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/01913120600689624", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049576531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/japplphysiol.00869.2012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052612961"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/wnl.0b013e3181d3e44b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064355106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/wnl.0b013e3181d3e44b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064355106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/wnl.0b013e3181d3e44b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064355106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diab.41.11.1422", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070736682"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.22-13-05581.2002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075081110"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077292400", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.16-03-00877.1996", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082858617"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-01", 
    "datePublishedReg": "2018-01-01", 
    "description": "Astrocyte-neuron lactate shuttle (ANLS) is a pathway that supplies glycogen-derived lactate to active neurons via monocarboxylate transporter 2 (MCT2), and is important for maintaining brain functions. Our study revealed alterations of ANLS with hippocampal hyper-glycogen levels and downregulated MCT2 protein levels underlying hippocampal dysfunctions as a complication in type 2 diabetic (T2DM) animals. Since T2DM rats exhibit brain dysfunctions involving several brain regions, we examined whether there might also be T2DM effects on ANLS's disturbances in other brain loci. OLETF rats exhibited significantly higher glycogen levels in the hippocampus, hypothalamus, and cerebral cortex than did LETO rats. MCT2 protein levels in OLETF rats decreased significantly in the hippocampus and hypothalamus compared to their controls, but a significant correlation with glycogen levels was only observed in the hippocampus. This suggests that the hippocampus may be more vulnerable to T2DM compared to other brain regions in the context of ANLS disruption.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s12576-016-0508-6", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.5859463", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6534665", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6052364", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.6069686", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.5846339", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1294916", 
        "issn": [
          "1880-6546", 
          "1880-6562"
        ], 
        "name": "The Journal of Physiological Sciences", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "68"
      }
    ], 
    "name": "Differential effects of type 2 diabetes on brain glycometabolism in rats: focus on glycogen and monocarboxylate transporter 2", 
    "pagination": "69-75", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "7f0c6902472a033e2f9d1b96ee40aa93caf9d4276c5bef9f015ed859187b6c63"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27987117"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101262417"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12576-016-0508-6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1026669073"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12576-016-0508-6", 
      "https://app.dimensions.ai/details/publication/pub.1026669073"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T09:50", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89786_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs12576-016-0508-6"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12576-016-0508-6'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12576-016-0508-6'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12576-016-0508-6'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12576-016-0508-6'


 

This table displays all metadata directly associated to this object as RDF triples.

221 TRIPLES      21 PREDICATES      62 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12576-016-0508-6 schema:about N1d987dc4c74442038e579898a16431a1
2 N2c92fede30c74b4d93836182200904f9
3 N3d857b393dde4b9089efead25df47945
4 N4d8c71e3680c4179890a2a9bfa0c6f1c
5 N5d11ba85fb1b411395276efb1ae1d02f
6 N908d71753ee94d0ea3d299a8eedbec02
7 Na39addd75d7f4595a59073a4bf775e5c
8 Na642f00141724d11b8f2b55d6d680404
9 Ncb8962ab61d648f2aea582343a4ae6db
10 Ncbb257330fc84684b453f530d314d6a9
11 Nccb6f2b3023e4423846f660431f8bcb6
12 anzsrc-for:11
13 anzsrc-for:1109
14 schema:author N809b045a6a8049d889eb62109a1be17d
15 schema:citation sg:pub.10.1007/s00125-016-4164-4
16 sg:pub.10.1007/s10072-015-2087-3
17 sg:pub.10.1007/s11064-015-1594-1
18 sg:pub.10.1038/ncomms4284
19 https://app.dimensions.ai/details/publication/pub.1077292400
20 https://doi.org/10.1016/0003-2697(74)90248-6
21 https://doi.org/10.1016/j.brainres.2012.08.056
22 https://doi.org/10.1016/j.cell.2011.02.018
23 https://doi.org/10.1016/j.neulet.2016.09.012
24 https://doi.org/10.1016/j.physbeh.2005.10.007
25 https://doi.org/10.1016/s0896-6273(00)81084-3
26 https://doi.org/10.1038/jcbfm.2011.149
27 https://doi.org/10.1080/01913120600689624
28 https://doi.org/10.1111/j.1471-4159.2005.03168.x
29 https://doi.org/10.1152/ajpendo.00525.2010
30 https://doi.org/10.1152/japplphysiol.00869.2012
31 https://doi.org/10.1212/wnl.0b013e3181d3e44b
32 https://doi.org/10.1371/journal.pone.0082991
33 https://doi.org/10.1523/jneurosci.16-03-00877.1996
34 https://doi.org/10.1523/jneurosci.22-13-05581.2002
35 https://doi.org/10.2174/157339909788166846
36 https://doi.org/10.2337/diab.41.11.1422
37 schema:datePublished 2018-01
38 schema:datePublishedReg 2018-01-01
39 schema:description Astrocyte-neuron lactate shuttle (ANLS) is a pathway that supplies glycogen-derived lactate to active neurons via monocarboxylate transporter 2 (MCT2), and is important for maintaining brain functions. Our study revealed alterations of ANLS with hippocampal hyper-glycogen levels and downregulated MCT2 protein levels underlying hippocampal dysfunctions as a complication in type 2 diabetic (T2DM) animals. Since T2DM rats exhibit brain dysfunctions involving several brain regions, we examined whether there might also be T2DM effects on ANLS's disturbances in other brain loci. OLETF rats exhibited significantly higher glycogen levels in the hippocampus, hypothalamus, and cerebral cortex than did LETO rats. MCT2 protein levels in OLETF rats decreased significantly in the hippocampus and hypothalamus compared to their controls, but a significant correlation with glycogen levels was only observed in the hippocampus. This suggests that the hippocampus may be more vulnerable to T2DM compared to other brain regions in the context of ANLS disruption.
40 schema:genre research_article
41 schema:inLanguage en
42 schema:isAccessibleForFree false
43 schema:isPartOf N85d258c7acdd4edfa121612bfa87aeec
44 Nd62a85e7eec34e38b8f7b4d2ef457148
45 sg:journal.1294916
46 schema:name Differential effects of type 2 diabetes on brain glycometabolism in rats: focus on glycogen and monocarboxylate transporter 2
47 schema:pagination 69-75
48 schema:productId N14b7c504a05e4501987f453a3499d946
49 N495fcf0595ac40748eb3581e84be9398
50 N9f2139f635a24556aa34e69d03271ab1
51 N9fd63cd097aa4f8bba1a15abd63cdf07
52 Ndae576c13f634293a9b0009803522c7e
53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026669073
54 https://doi.org/10.1007/s12576-016-0508-6
55 schema:sdDatePublished 2019-04-11T09:50
56 schema:sdLicense https://scigraph.springernature.com/explorer/license/
57 schema:sdPublisher Ne7cd447aaf3b48039566e5173a7d6664
58 schema:url https://link.springer.com/10.1007%2Fs12576-016-0508-6
59 sgo:license sg:explorer/license/
60 sgo:sdDataset articles
61 rdf:type schema:ScholarlyArticle
62 N04de4d9dfeba4404af35b6cc44fb7ed4 rdf:first sg:person.012771022601.81
63 rdf:rest N56f63f53ff574e5e88b04cf7276acf19
64 N14b7c504a05e4501987f453a3499d946 schema:name doi
65 schema:value 10.1007/s12576-016-0508-6
66 rdf:type schema:PropertyValue
67 N1d987dc4c74442038e579898a16431a1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
68 schema:name Male
69 rdf:type schema:DefinedTerm
70 N2c92fede30c74b4d93836182200904f9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
71 schema:name Glycogen
72 rdf:type schema:DefinedTerm
73 N3d857b393dde4b9089efead25df47945 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name Rats
75 rdf:type schema:DefinedTerm
76 N495fcf0595ac40748eb3581e84be9398 schema:name dimensions_id
77 schema:value pub.1026669073
78 rdf:type schema:PropertyValue
79 N4d8c71e3680c4179890a2a9bfa0c6f1c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Monocarboxylic Acid Transporters
81 rdf:type schema:DefinedTerm
82 N56f63f53ff574e5e88b04cf7276acf19 rdf:first sg:person.0603002311.15
83 rdf:rest rdf:nil
84 N5d11ba85fb1b411395276efb1ae1d02f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Diabetes Mellitus, Type 2
86 rdf:type schema:DefinedTerm
87 N809b045a6a8049d889eb62109a1be17d rdf:first sg:person.010003120601.28
88 rdf:rest N973d2b26e5594ba0b1d6fa8a571f2f48
89 N85d258c7acdd4edfa121612bfa87aeec schema:volumeNumber 68
90 rdf:type schema:PublicationVolume
91 N908d71753ee94d0ea3d299a8eedbec02 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Astrocytes
93 rdf:type schema:DefinedTerm
94 N973d2b26e5594ba0b1d6fa8a571f2f48 rdf:first sg:person.01175270476.03
95 rdf:rest Nf7673321631d46ff81f52240472f1248
96 N9f2139f635a24556aa34e69d03271ab1 schema:name readcube_id
97 schema:value 7f0c6902472a033e2f9d1b96ee40aa93caf9d4276c5bef9f015ed859187b6c63
98 rdf:type schema:PropertyValue
99 N9fd63cd097aa4f8bba1a15abd63cdf07 schema:name pubmed_id
100 schema:value 27987117
101 rdf:type schema:PropertyValue
102 Na39addd75d7f4595a59073a4bf775e5c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Animals
104 rdf:type schema:DefinedTerm
105 Na642f00141724d11b8f2b55d6d680404 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Hippocampus
107 rdf:type schema:DefinedTerm
108 Ncb8962ab61d648f2aea582343a4ae6db schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Rats, Inbred OLETF
110 rdf:type schema:DefinedTerm
111 Ncbb257330fc84684b453f530d314d6a9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Neurons
113 rdf:type schema:DefinedTerm
114 Nccb6f2b3023e4423846f660431f8bcb6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Cerebral Cortex
116 rdf:type schema:DefinedTerm
117 Nd62a85e7eec34e38b8f7b4d2ef457148 schema:issueNumber 1
118 rdf:type schema:PublicationIssue
119 Ndae576c13f634293a9b0009803522c7e schema:name nlm_unique_id
120 schema:value 101262417
121 rdf:type schema:PropertyValue
122 Ne7cd447aaf3b48039566e5173a7d6664 schema:name Springer Nature - SN SciGraph project
123 rdf:type schema:Organization
124 Nf7673321631d46ff81f52240472f1248 rdf:first sg:person.01033617617.27
125 rdf:rest N04de4d9dfeba4404af35b6cc44fb7ed4
126 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
127 schema:name Medical and Health Sciences
128 rdf:type schema:DefinedTerm
129 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
130 schema:name Neurosciences
131 rdf:type schema:DefinedTerm
132 sg:grant.5846339 http://pending.schema.org/fundedItem sg:pub.10.1007/s12576-016-0508-6
133 rdf:type schema:MonetaryGrant
134 sg:grant.5859463 http://pending.schema.org/fundedItem sg:pub.10.1007/s12576-016-0508-6
135 rdf:type schema:MonetaryGrant
136 sg:grant.6052364 http://pending.schema.org/fundedItem sg:pub.10.1007/s12576-016-0508-6
137 rdf:type schema:MonetaryGrant
138 sg:grant.6069686 http://pending.schema.org/fundedItem sg:pub.10.1007/s12576-016-0508-6
139 rdf:type schema:MonetaryGrant
140 sg:grant.6534665 http://pending.schema.org/fundedItem sg:pub.10.1007/s12576-016-0508-6
141 rdf:type schema:MonetaryGrant
142 sg:journal.1294916 schema:issn 1880-6546
143 1880-6562
144 schema:name The Journal of Physiological Sciences
145 rdf:type schema:Periodical
146 sg:person.010003120601.28 schema:affiliation https://www.grid.ac/institutes/grid.20515.33
147 schema:familyName Shima
148 schema:givenName Takeru
149 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010003120601.28
150 rdf:type schema:Person
151 sg:person.01033617617.27 schema:affiliation https://www.grid.ac/institutes/grid.20515.33
152 schema:familyName Matsui
153 schema:givenName Takashi
154 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033617617.27
155 rdf:type schema:Person
156 sg:person.01175270476.03 schema:affiliation https://www.grid.ac/institutes/grid.20515.33
157 schema:familyName Jesmin
158 schema:givenName Subrina
159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175270476.03
160 rdf:type schema:Person
161 sg:person.012771022601.81 schema:affiliation https://www.grid.ac/institutes/grid.20515.33
162 schema:familyName Soya
163 schema:givenName Mariko
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012771022601.81
165 rdf:type schema:Person
166 sg:person.0603002311.15 schema:affiliation https://www.grid.ac/institutes/grid.20515.33
167 schema:familyName Soya
168 schema:givenName Hideaki
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0603002311.15
170 rdf:type schema:Person
171 sg:pub.10.1007/s00125-016-4164-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042067335
172 https://doi.org/10.1007/s00125-016-4164-4
173 rdf:type schema:CreativeWork
174 sg:pub.10.1007/s10072-015-2087-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038296725
175 https://doi.org/10.1007/s10072-015-2087-3
176 rdf:type schema:CreativeWork
177 sg:pub.10.1007/s11064-015-1594-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019080237
178 https://doi.org/10.1007/s11064-015-1594-1
179 rdf:type schema:CreativeWork
180 sg:pub.10.1038/ncomms4284 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000968027
181 https://doi.org/10.1038/ncomms4284
182 rdf:type schema:CreativeWork
183 https://app.dimensions.ai/details/publication/pub.1077292400 schema:CreativeWork
184 https://doi.org/10.1016/0003-2697(74)90248-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008331910
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1016/j.brainres.2012.08.056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011527505
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1016/j.cell.2011.02.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028061932
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1016/j.neulet.2016.09.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012008008
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1016/j.physbeh.2005.10.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004451669
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1016/s0896-6273(00)81084-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031361052
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1038/jcbfm.2011.149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002617488
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1080/01913120600689624 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049576531
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1111/j.1471-4159.2005.03168.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024544157
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1152/ajpendo.00525.2010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002358342
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1152/japplphysiol.00869.2012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052612961
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1212/wnl.0b013e3181d3e44b schema:sameAs https://app.dimensions.ai/details/publication/pub.1064355106
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1371/journal.pone.0082991 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014319070
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1523/jneurosci.16-03-00877.1996 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082858617
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1523/jneurosci.22-13-05581.2002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075081110
213 rdf:type schema:CreativeWork
214 https://doi.org/10.2174/157339909788166846 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011504466
215 rdf:type schema:CreativeWork
216 https://doi.org/10.2337/diab.41.11.1422 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070736682
217 rdf:type schema:CreativeWork
218 https://www.grid.ac/institutes/grid.20515.33 schema:alternateName University of Tsukuba
219 schema:name Department of Sports Neuroscience, Advanced Research Initiative for Human High Performance (ARIHHP), University of Tsukuba, 1-1-1 Tennoudai, 305-8574, Tsukuba, Ibaraki, Japan
220 Laboratory of Exercise Biochemistry and Neuroendocrinology, Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennoudai, 305-8574, Tsukuba, Ibaraki, Japan
221 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...