VEGFA rSNPs, transcriptional factor binding sites and human disease View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-01

AUTHORS

Norman E. Buroker

ABSTRACT

Three regulatory SNPs (rSNPs) in the promoter region of the vascular endothelial growth factor-A (VEGFA) gene have been significantly associated with several human diseases or conditions. The rSNP alleles alter the DNA landscape for potential transcriptional factors to attach, resulting in changes in transcriptional factor binding sites (TFBS). These TFBS changes are examined with respect to the human diseases which have been found to be significantly associated with the rSNPs. More... »

PAGES

73-76

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12576-013-0293-4

DOI

http://dx.doi.org/10.1007/s12576-013-0293-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1051954487

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24097272


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