Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-03-28

AUTHORS

Takehito Kemuriyama, Megumi Tandai-Hiruma, Kazuo Kato, Hiroyuki Ohta, Satoshi Maruyama, Yoshiaki Sato, Yasuhiro Nishida

ABSTRACT

The effects of endogenous angiotensin II (Ang II) and neuronal nitric oxide synthase (nNOS) on tonic sympathetic activity were studied in salt-sensitive hypertension-induced heart failure. Dahl salt-sensitive rats were fed 8% NaCl diet for 9 weeks to induce chronic heart failure (CHF-DSS). The effects of intravenous administration of a selective nNOS inhibitor, S-methyl-l-thiocitrulline (SMTC), and an Ang II type 1-receptor blocker, losartan, on renal sympathetic nerve activity (RSNA) were examined in chronically instrumented conscious rats. Baroreceptor (baro)-unloaded RSNA was obtained by decreasing arterial pressure with caval occlusion to determine tonic RSNA. SMTC significantly decreased baro-unloaded RSNA, and subsequent losartan recovered baro-unloaded RSNA to the control level in CHF-DSS rats. To compare the effects of the inhibitors between low- and high-activity states of the renin–angiotensin system (RAS), Sprague–Dawley rats were fed low (0.04%)- or high (8%)-salt diets. A significant difference was found in the effects of SMTC and/or losartan on RSNA between the high- and low-RAS states, which suggested that there is a difference in the effect of endogenous Ang II on RSNA between salt-induced and other-type heart failure. To examine the effects of heart failure on brain-tissue nNOS activity, we measured the activities of the diencephalon in heart-failure rats. Heart failure significantly suppressed diencephalon nNOS activity, which was significantly different from the results in salt-sensitive hypertension without heart failure. These results suggest that endogenous Ang II has fewer effects, but nNOS has excitatory effects on tonic RSNA in salt-sensitive hypertension-induced heart failure. More... »

PAGES

275-281

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12576-009-0034-x

DOI

http://dx.doi.org/10.1007/s12576-009-0034-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018808949

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19340531


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1115", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Pharmacology and Pharmaceutical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Angiotensin II", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Angiotensin II Type 1 Receptor Blockers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Citrulline", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enzyme Inhibitors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart Failure", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypertension", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Losartan", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nitric Oxide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nitric Oxide Synthase", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nitric Oxide Synthase Type I", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pressoreceptors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Inbred Dahl", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Renin-Angiotensin System", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sodium Chloride, Dietary", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sympathetic Nervous System", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thiourea", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.416614.0", 
          "name": [
            "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kemuriyama", 
        "givenName": "Takehito", 
        "id": "sg:person.01212023505.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212023505.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.416614.0", 
          "name": [
            "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tandai-Hiruma", 
        "givenName": "Megumi", 
        "id": "sg:person.01143710305.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143710305.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.416614.0", 
          "name": [
            "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kato", 
        "givenName": "Kazuo", 
        "id": "sg:person.01116610266.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01116610266.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.416614.0", 
          "name": [
            "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ohta", 
        "givenName": "Hiroyuki", 
        "id": "sg:person.01162652575.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162652575.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.416614.0", 
          "name": [
            "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maruyama", 
        "givenName": "Satoshi", 
        "id": "sg:person.0761457670.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761457670.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.416614.0", 
          "name": [
            "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sato", 
        "givenName": "Yoshiaki", 
        "id": "sg:person.01075706270.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01075706270.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan", 
          "id": "http://www.grid.ac/institutes/grid.416614.0", 
          "name": [
            "Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nishida", 
        "givenName": "Yasuhiro", 
        "id": "sg:person.01212134670.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212134670.96"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1023/a:1009894007055", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031444026", 
          "https://doi.org/10.1023/a:1009894007055"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/347768a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005544862", 
          "https://doi.org/10.1038/347768a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2009-03-28", 
    "datePublishedReg": "2009-03-28", 
    "description": "The effects of endogenous angiotensin II (Ang II) and neuronal nitric oxide synthase (nNOS) on tonic sympathetic activity were studied in salt-sensitive hypertension-induced heart failure. Dahl salt-sensitive rats were fed 8% NaCl diet for 9\u00a0weeks to induce chronic heart failure (CHF-DSS). The effects of intravenous administration of a selective nNOS inhibitor, S-methyl-l-thiocitrulline (SMTC), and an Ang II type 1-receptor blocker, losartan, on renal sympathetic nerve activity (RSNA) were examined in chronically instrumented conscious rats. Baroreceptor (baro)-unloaded RSNA was obtained by decreasing arterial pressure with caval occlusion to determine tonic RSNA. SMTC significantly decreased baro-unloaded RSNA, and subsequent losartan recovered baro-unloaded RSNA to the control level in CHF-DSS rats. To compare the effects of the inhibitors between low- and high-activity states of the renin\u2013angiotensin system (RAS), Sprague\u2013Dawley rats were fed low (0.04%)- or high (8%)-salt diets. A significant difference was found in the effects of SMTC and/or losartan on RSNA between the high- and low-RAS states, which suggested that there is a difference in the effect of endogenous Ang II on RSNA between salt-induced and other-type heart failure. To examine the effects of heart failure on brain-tissue nNOS activity, we measured the activities of the diencephalon in heart-failure rats. Heart failure significantly suppressed diencephalon nNOS activity, which was significantly different from the results in salt-sensitive hypertension without heart failure. These results suggest that endogenous Ang II has fewer effects, but nNOS has excitatory effects on tonic RSNA in salt-sensitive hypertension-induced heart failure.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s12576-009-0034-x", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1294916", 
        "issn": [
          "1880-6546", 
          "1880-6562"
        ], 
        "name": "The Journal of Physiological Sciences", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "59"
      }
    ], 
    "keywords": [
      "renal sympathetic nerve activity", 
      "hypertension-induced heart failure", 
      "neuronal nitric oxide synthase", 
      "tonic renal sympathetic nerve activity", 
      "endogenous angiotensin II", 
      "sympathetic nerve activity", 
      "renin-angiotensin system", 
      "heart failure", 
      "endogenous Ang II", 
      "nitric oxide synthase", 
      "nerve activity", 
      "Ang II", 
      "excitatory effects", 
      "angiotensin II", 
      "oxide synthase", 
      "Dahl salt-sensitive rats", 
      "tonic sympathetic activity", 
      "Ang II type", 
      "effects of SMTC", 
      "chronic heart failure", 
      "heart failure rats", 
      "salt-sensitive rats", 
      "salt-sensitive hypertension", 
      "Sprague-Dawley rats", 
      "selective nNOS inhibitor", 
      "NaCl diet", 
      "arterial pressure", 
      "salt diet", 
      "sympathetic activity", 
      "conscious rats", 
      "nNOS activity", 
      "nNOS activity", 
      "intravenous administration", 
      "nNOS inhibitor", 
      "caval occlusion", 
      "fed 8", 
      "rats", 
      "control levels", 
      "losartan", 
      "significant differences", 
      "diet", 
      "II type", 
      "failure", 
      "inhibitors", 
      "hypertension", 
      "baroreceptors", 
      "synthase", 
      "thiocitrulline", 
      "activity", 
      "blockers", 
      "SMTC", 
      "administration", 
      "diencephalon", 
      "weeks", 
      "occlusion", 
      "effect", 
      "differences", 
      "levels", 
      "methyl", 
      "pressure", 
      "results", 
      "high activity state", 
      "types", 
      "state", 
      "system", 
      "salt-sensitive hypertension-induced heart failure", 
      "unloaded RSNA", 
      "baro-unloaded RSNA", 
      "subsequent losartan", 
      "CHF-DSS rats", 
      "low-RAS states", 
      "type heart failure", 
      "brain-tissue nNOS activity", 
      "diencephalon nNOS activity"
    ], 
    "name": "Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure", 
    "pagination": "275-281", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1018808949"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12576-009-0034-x"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "19340531"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12576-009-0034-x", 
      "https://app.dimensions.ai/details/publication/pub.1018808949"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:19", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_487.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s12576-009-0034-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12576-009-0034-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12576-009-0034-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12576-009-0034-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12576-009-0034-x'


 

This table displays all metadata directly associated to this object as RDF triples.

273 TRIPLES      22 PREDICATES      123 URIs      112 LITERALS      28 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12576-009-0034-x schema:about N01a56ea933d740f6959bb1891ae04d6e
2 N242b07325cc7417db5a6c7293dbb0326
3 N2e1d37e9f0164619980ffc2979130cc2
4 N42727bc0c86e415b83e61f9e9a750d5e
5 N4e29a8e08af74bec93f59d6d9a8157ee
6 N544cf1a21fab4b01a77aa487d62df890
7 N5e83711bea6e41f0ab8835f0ab7788a5
8 N5e8a31add9254366afae029702259d93
9 N5f900d8f41e24a69830ce14b4290eabc
10 N82e9fd6d348f4b40b355f984be388423
11 N927a26254aab42a8a9519096dc7fb7e1
12 N9bcec7fbef3b4689a9b3cdd76735c42d
13 Na92b2fc552f84b808a6a91e59ef2f29c
14 Nabb0119cf78349c18f2a6e7cddff5126
15 Nadf795bfa6414702bde889e83f5fd79b
16 Nbdc53bbdaa4e4844be748572f5330b9f
17 Nd16a0232224448a48658bfa7278cef91
18 Ne59a21fd1a6d4cc68bd1e9848fc0fa48
19 Ne5d64f1173cc4b458d73c3b420d91317
20 Ne9683afa79a44e59974fe076e3b89ff2
21 Nf683cf065e394af0b76a5803d3a11189
22 anzsrc-for:11
23 anzsrc-for:1102
24 anzsrc-for:1115
25 schema:author Nf8e722d4a3af4dd5b96010804d20aa22
26 schema:citation sg:pub.10.1023/a:1009894007055
27 sg:pub.10.1038/347768a0
28 schema:datePublished 2009-03-28
29 schema:datePublishedReg 2009-03-28
30 schema:description The effects of endogenous angiotensin II (Ang II) and neuronal nitric oxide synthase (nNOS) on tonic sympathetic activity were studied in salt-sensitive hypertension-induced heart failure. Dahl salt-sensitive rats were fed 8% NaCl diet for 9 weeks to induce chronic heart failure (CHF-DSS). The effects of intravenous administration of a selective nNOS inhibitor, S-methyl-l-thiocitrulline (SMTC), and an Ang II type 1-receptor blocker, losartan, on renal sympathetic nerve activity (RSNA) were examined in chronically instrumented conscious rats. Baroreceptor (baro)-unloaded RSNA was obtained by decreasing arterial pressure with caval occlusion to determine tonic RSNA. SMTC significantly decreased baro-unloaded RSNA, and subsequent losartan recovered baro-unloaded RSNA to the control level in CHF-DSS rats. To compare the effects of the inhibitors between low- and high-activity states of the renin–angiotensin system (RAS), Sprague–Dawley rats were fed low (0.04%)- or high (8%)-salt diets. A significant difference was found in the effects of SMTC and/or losartan on RSNA between the high- and low-RAS states, which suggested that there is a difference in the effect of endogenous Ang II on RSNA between salt-induced and other-type heart failure. To examine the effects of heart failure on brain-tissue nNOS activity, we measured the activities of the diencephalon in heart-failure rats. Heart failure significantly suppressed diencephalon nNOS activity, which was significantly different from the results in salt-sensitive hypertension without heart failure. These results suggest that endogenous Ang II has fewer effects, but nNOS has excitatory effects on tonic RSNA in salt-sensitive hypertension-induced heart failure.
31 schema:genre article
32 schema:inLanguage en
33 schema:isAccessibleForFree true
34 schema:isPartOf N77aeb6bcd2e24315bdce348f0167f29a
35 Nd417779c80784d3581908f6e539c35a5
36 sg:journal.1294916
37 schema:keywords Ang II
38 Ang II type
39 CHF-DSS rats
40 Dahl salt-sensitive rats
41 II type
42 NaCl diet
43 SMTC
44 Sprague-Dawley rats
45 activity
46 administration
47 angiotensin II
48 arterial pressure
49 baro-unloaded RSNA
50 baroreceptors
51 blockers
52 brain-tissue nNOS activity
53 caval occlusion
54 chronic heart failure
55 conscious rats
56 control levels
57 diencephalon
58 diencephalon nNOS activity
59 diet
60 differences
61 effect
62 effects of SMTC
63 endogenous Ang II
64 endogenous angiotensin II
65 excitatory effects
66 failure
67 fed 8
68 heart failure
69 heart failure rats
70 high activity state
71 hypertension
72 hypertension-induced heart failure
73 inhibitors
74 intravenous administration
75 levels
76 losartan
77 low-RAS states
78 methyl
79 nNOS activity
80 nNOS inhibitor
81 nerve activity
82 neuronal nitric oxide synthase
83 nitric oxide synthase
84 occlusion
85 oxide synthase
86 pressure
87 rats
88 renal sympathetic nerve activity
89 renin-angiotensin system
90 results
91 salt diet
92 salt-sensitive hypertension
93 salt-sensitive hypertension-induced heart failure
94 salt-sensitive rats
95 selective nNOS inhibitor
96 significant differences
97 state
98 subsequent losartan
99 sympathetic activity
100 sympathetic nerve activity
101 synthase
102 system
103 thiocitrulline
104 tonic renal sympathetic nerve activity
105 tonic sympathetic activity
106 type heart failure
107 types
108 unloaded RSNA
109 weeks
110 schema:name Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure
111 schema:pagination 275-281
112 schema:productId N187cfc20e95b42ebbecc5ef1f17e9eba
113 Ncc38dd9ae5e147718866b3304ae0cd07
114 Ne713d6d45cc04303aab5cd8aaec990e1
115 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018808949
116 https://doi.org/10.1007/s12576-009-0034-x
117 schema:sdDatePublished 2022-01-01T18:19
118 schema:sdLicense https://scigraph.springernature.com/explorer/license/
119 schema:sdPublisher N5bae856cde5d43b29a2d0f80429aa4f1
120 schema:url https://doi.org/10.1007/s12576-009-0034-x
121 sgo:license sg:explorer/license/
122 sgo:sdDataset articles
123 rdf:type schema:ScholarlyArticle
124 N01a56ea933d740f6959bb1891ae04d6e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Heart Failure
126 rdf:type schema:DefinedTerm
127 N149651ebcddb4896a40967e28959628f rdf:first sg:person.01212134670.96
128 rdf:rest rdf:nil
129 N187cfc20e95b42ebbecc5ef1f17e9eba schema:name dimensions_id
130 schema:value pub.1018808949
131 rdf:type schema:PropertyValue
132 N242b07325cc7417db5a6c7293dbb0326 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Enzyme Inhibitors
134 rdf:type schema:DefinedTerm
135 N2e1d37e9f0164619980ffc2979130cc2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Hypertension
137 rdf:type schema:DefinedTerm
138 N34907037f28b425ea969bd24323d19f1 rdf:first sg:person.0761457670.42
139 rdf:rest Nd190ff61a88a4c12924a512f04864f52
140 N3ee8c277cdb242b5926da1194107789c rdf:first sg:person.01143710305.04
141 rdf:rest Nacef8da190f840cdb0a35b01a946b9ac
142 N42727bc0c86e415b83e61f9e9a750d5e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Male
144 rdf:type schema:DefinedTerm
145 N4e29a8e08af74bec93f59d6d9a8157ee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Losartan
147 rdf:type schema:DefinedTerm
148 N544cf1a21fab4b01a77aa487d62df890 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Angiotensin II
150 rdf:type schema:DefinedTerm
151 N5bae856cde5d43b29a2d0f80429aa4f1 schema:name Springer Nature - SN SciGraph project
152 rdf:type schema:Organization
153 N5e83711bea6e41f0ab8835f0ab7788a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Nitric Oxide Synthase Type I
155 rdf:type schema:DefinedTerm
156 N5e8a31add9254366afae029702259d93 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Sympathetic Nervous System
158 rdf:type schema:DefinedTerm
159 N5f900d8f41e24a69830ce14b4290eabc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Rats
161 rdf:type schema:DefinedTerm
162 N77aeb6bcd2e24315bdce348f0167f29a schema:issueNumber 4
163 rdf:type schema:PublicationIssue
164 N82e9fd6d348f4b40b355f984be388423 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Animals
166 rdf:type schema:DefinedTerm
167 N927a26254aab42a8a9519096dc7fb7e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Kidney
169 rdf:type schema:DefinedTerm
170 N9bcec7fbef3b4689a9b3cdd76735c42d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Renin-Angiotensin System
172 rdf:type schema:DefinedTerm
173 Na92b2fc552f84b808a6a91e59ef2f29c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Rats, Inbred Dahl
175 rdf:type schema:DefinedTerm
176 Nabb0119cf78349c18f2a6e7cddff5126 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
177 schema:name Angiotensin II Type 1 Receptor Blockers
178 rdf:type schema:DefinedTerm
179 Nacef8da190f840cdb0a35b01a946b9ac rdf:first sg:person.01116610266.82
180 rdf:rest Nbf7d5a59bcfc40e28bce104436546ad7
181 Nadf795bfa6414702bde889e83f5fd79b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
182 schema:name Citrulline
183 rdf:type schema:DefinedTerm
184 Nbdc53bbdaa4e4844be748572f5330b9f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
185 schema:name Nitric Oxide Synthase
186 rdf:type schema:DefinedTerm
187 Nbf7d5a59bcfc40e28bce104436546ad7 rdf:first sg:person.01162652575.57
188 rdf:rest N34907037f28b425ea969bd24323d19f1
189 Ncc38dd9ae5e147718866b3304ae0cd07 schema:name doi
190 schema:value 10.1007/s12576-009-0034-x
191 rdf:type schema:PropertyValue
192 Nd16a0232224448a48658bfa7278cef91 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
193 schema:name Brain
194 rdf:type schema:DefinedTerm
195 Nd190ff61a88a4c12924a512f04864f52 rdf:first sg:person.01075706270.33
196 rdf:rest N149651ebcddb4896a40967e28959628f
197 Nd417779c80784d3581908f6e539c35a5 schema:volumeNumber 59
198 rdf:type schema:PublicationVolume
199 Ne59a21fd1a6d4cc68bd1e9848fc0fa48 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
200 schema:name Nitric Oxide
201 rdf:type schema:DefinedTerm
202 Ne5d64f1173cc4b458d73c3b420d91317 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
203 schema:name Pressoreceptors
204 rdf:type schema:DefinedTerm
205 Ne713d6d45cc04303aab5cd8aaec990e1 schema:name pubmed_id
206 schema:value 19340531
207 rdf:type schema:PropertyValue
208 Ne9683afa79a44e59974fe076e3b89ff2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
209 schema:name Sodium Chloride, Dietary
210 rdf:type schema:DefinedTerm
211 Nf683cf065e394af0b76a5803d3a11189 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
212 schema:name Thiourea
213 rdf:type schema:DefinedTerm
214 Nf8e722d4a3af4dd5b96010804d20aa22 rdf:first sg:person.01212023505.37
215 rdf:rest N3ee8c277cdb242b5926da1194107789c
216 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
217 schema:name Medical and Health Sciences
218 rdf:type schema:DefinedTerm
219 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
220 schema:name Cardiorespiratory Medicine and Haematology
221 rdf:type schema:DefinedTerm
222 anzsrc-for:1115 schema:inDefinedTermSet anzsrc-for:
223 schema:name Pharmacology and Pharmaceutical Sciences
224 rdf:type schema:DefinedTerm
225 sg:journal.1294916 schema:issn 1880-6546
226 1880-6562
227 schema:name The Journal of Physiological Sciences
228 schema:publisher Springer Nature
229 rdf:type schema:Periodical
230 sg:person.01075706270.33 schema:affiliation grid-institutes:grid.416614.0
231 schema:familyName Sato
232 schema:givenName Yoshiaki
233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01075706270.33
234 rdf:type schema:Person
235 sg:person.01116610266.82 schema:affiliation grid-institutes:grid.416614.0
236 schema:familyName Kato
237 schema:givenName Kazuo
238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01116610266.82
239 rdf:type schema:Person
240 sg:person.01143710305.04 schema:affiliation grid-institutes:grid.416614.0
241 schema:familyName Tandai-Hiruma
242 schema:givenName Megumi
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01143710305.04
244 rdf:type schema:Person
245 sg:person.01162652575.57 schema:affiliation grid-institutes:grid.416614.0
246 schema:familyName Ohta
247 schema:givenName Hiroyuki
248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162652575.57
249 rdf:type schema:Person
250 sg:person.01212023505.37 schema:affiliation grid-institutes:grid.416614.0
251 schema:familyName Kemuriyama
252 schema:givenName Takehito
253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212023505.37
254 rdf:type schema:Person
255 sg:person.01212134670.96 schema:affiliation grid-institutes:grid.416614.0
256 schema:familyName Nishida
257 schema:givenName Yasuhiro
258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212134670.96
259 rdf:type schema:Person
260 sg:person.0761457670.42 schema:affiliation grid-institutes:grid.416614.0
261 schema:familyName Maruyama
262 schema:givenName Satoshi
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761457670.42
264 rdf:type schema:Person
265 sg:pub.10.1023/a:1009894007055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031444026
266 https://doi.org/10.1023/a:1009894007055
267 rdf:type schema:CreativeWork
268 sg:pub.10.1038/347768a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005544862
269 https://doi.org/10.1038/347768a0
270 rdf:type schema:CreativeWork
271 grid-institutes:grid.416614.0 schema:alternateName Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan
272 schema:name Department of Physiology, National Defense Medical College, 3-2 Namiki, 359-8513, Tokorozawa, Saitama, Japan
273 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...