Adrenal hemorrhage in newborns: a retrospective study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-08-27

AUTHORS

Mehmet Mutlu, Gülay Karagüzel, Yakup Aslan, Ayşegül Cansu, Ayşenur Ökten

ABSTRACT

BackgroundAdrenal hemorrhage (AH) is a relatively uncommon condition in neonates. This study aimed to review the clinical, laboratory and ultrasonographic findings of AH in newborns.MethodsThe medical records of 13 newborns with AH who had been admitted to our neonatal intensive care unit were retrospectively reviewed.ResultsOf the 13 newborns with AH, 8 (62%) were term and 10 (77%) were male babies. Clinical presentations included neonatal jaundice (85%), paleness and/or flank mass (38%), discoloration of the scrotum (15%), and hypotonia/lethargy or hypotension (8%). Five newborns had anemia and four had adrenal insufficiency. Adrenal insufficiency was observed in 80% of the premature infants with AH. AH occurred on the right side in 9 patients (69%). The most predisposing cause of AH was disseminated intravascular coagulation secondary to sepsis or perinatal hypoxia in preterm infants, and large for gestational age in term infants. Ultrasonography (USG) revealed a hypoechoic mass in 7 newborns (54%), a mixed solid-liquid mass in 5 (38%), and an echogenic mass (8%) in 1. Hemorrhage disappeared within 8.6±4.5 (4–16) weeks.ConclusionsAH occurs in the newborns with unexplained jaundice. Adrenal insufficiency is more frequent in preterm than in mature infants. Abdominal USG is required to determine AH in a newborn with swelling and bluish discoloration of the scrotum. Serial USG is the best modality for monitoring AH to prevent unnecessary surgery. More... »

PAGES

355

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12519-011-0259-7

DOI

http://dx.doi.org/10.1007/s12519-011-0259-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1030456058

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21874621


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