PS4 - 19. Expression of lipid genes, but not adipokine genes, in visceral adipose tissue is related to liver damage ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-11

AUTHORS

Marcel Wolfs, Lude Franke, Jingyuan Fu, Bart van de Sluis, Ann Driessen, Sander Rensen, Jan-Willem Greve, Wim Buurman, Timon van Haeften, Ludger Scheja, Ciska Wijmenga, Marten Hofker

ABSTRACT

Obesity increases the risk to develop liver steatosis, inflammation, and consequently severe liver damage. This risk is associated with an increased flow of lipids and signaling molecules (adipokines), secreted by adipose tissue, through the liver. However, the relevance of lipids and adipokines in this crosstalk between adipose tissue and liver in obesity-related liver pathology is largely unknown. Therefore we investigated to what extend the expression of genes involved in lipid metabolism and adipokine genes in visceral adipose tissue is correlated to liver pathology in obese individuals. More... »

PAGES

103-103

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12467-011-0044-1

DOI

http://dx.doi.org/10.1007/s12467-011-0044-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1049680500


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172 schema:name Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht UMC, Maastricht, The Netherlands
173 rdf:type schema:Organization
174 grid-institutes:grid.7692.a schema:alternateName Department of Internal Medicine, UMC Utrecht, Utrecht, The Netherlands
175 schema:name Department of Internal Medicine, UMC Utrecht, Utrecht, The Netherlands
176 Pathology and Medical Biology; Molecular Genetics, UMC Groningen, University of Groningen, Groningen, The Netherlands
177 rdf:type schema:Organization
 




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