Scan-rescan measurement repeatability of 18F-FDG PET/MR imaging of vascular inflammation View Full Text


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Article Info

DATE

2021-05-27

AUTHORS

Philip M. Robson, Audrey Kaufman, Alison Pruzan, Marc R. Dweck, Maria-Giovanna Trivieri, Ronan Abgral, Nicolas A. Karakatsanis, Patrick M. Brunner, Emma Guttman, Zahi A. Fayad, Venkatesh Mani

ABSTRACT

Non-invasive positron emission tomography (PET) of vascular inflammation and atherosclerotic plaque by identifying increased uptake of 18F-fluordeoxyglucose (18F-FDG) is a powerful tool for monitoring disease activity, progression, and its response to therapy. 18F-FDG PET/computed tomography (PET/CT) of the aorta and carotid arteries has become widely used to assess changes in inflammation in clinical trials. However, the recent advent of hybrid PET/magnetic resonance (PET/MR) scanners has advantages for vascular imaging due to the reduction in radiation exposure and improved soft tissue contrast of MR compared to CT. Important for research and clinical use is an understanding of the scan-rescan repeatability of the PET measurement. While this has been studied for PET/CT, no data is currently available for vascular PET/MR imaging. In this study, we determined the scan-rescan measurement repeatability of 18F-FDG PET/MR in the aorta and carotid arteries was less than 5%, comparable to similar findings for 18F-FDG PET/CT. More... »

PAGES

1-11

References to SciGraph publications

  • 2016-10-13. Short-term changes in arterial inflammation predict long-term changes in atherosclerosis progression in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2014-04-16. Higher reliability of 18F-FDG target background ratio compared to standardized uptake value in vulnerable carotid plaque detection: a pilot study in ANNALS OF NUCLEAR MEDICINE
  • 2015-10-03. High-risk plaque features can be detected in non-stenotic carotid plaques of patients with ischaemic stroke classified as cryptogenic using combined 18F-FDG PET/MR imaging in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2013-08-14. The complementary roles of dynamic contrast-enhanced MRI and 18F-fluorodeoxyglucose PET/CT for imaging of carotid atherosclerosis in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2014-01-24. Predictors of change in carotid atherosclerotic plaque inflammation and burden as measured by 18-FDG-PET and MRI, respectively, in the dal-PLAQUE study in THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
  • 2019-10-30. Hybrid PET- and MR-driven attenuation correction for enhanced 18F-NaF and 18F-FDG quantification in cardiovascular PET/MR imaging in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2009-11. Statistical power analyses using G*Power 3.1: Tests for correlation and regression analyses in BEHAVIOR RESEARCH METHODS
  • 2020-01-02. Assessing the qualitative and quantitative impacts of simple two-class vs multiple tissue-class MR-based attenuation correction for cardiac PET/MR in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2016-04-26. Dynamic Contrast-Enhanced MRI to Study Atherosclerotic Plaque Microvasculature in CURRENT ATHEROSCLEROSIS REPORTS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12350-021-02627-5

    DOI

    http://dx.doi.org/10.1007/s12350-021-02627-5

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1138399809

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/34046803


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