First comparison of performances between the new whole-body cadmium-zinc-telluride SPECT-CT camera and a dedicated cardiac CZT camera for myocardial perfusion ... View Full Text


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Article Info

DATE

2019-04-08

AUTHORS

Maxime Morelle, Dimitri Bellevre, Claude Hossein-Foucher, Alain Manrique, Alban Bailliez

ABSTRACT

BACKGROUND: Dedicated cardiac Cadmium-zinc-telluride (CZT) cameras show superior performances compared with Anger systems, particularly in terms of spatial resolution and count sensitivity. This study evaluated the performances of a new polyvalent whole body CZT camera (DNM 670CZT) compared with a cardiac dedicated CZT camera (DNM 530c) for myocardial perfusion SPECT. METHODS: The spatial resolution was evaluated with three linear sources filled with 99mTc. We used a cardiac phantom to evaluate count sensitivity, sharpness index, contrast-to-noise ratio, wall thickness, non-uniformity index, perfusion scores and ventricle volumes for both cameras. The impact of matrix size, and acquisition time was investigated. Concordance between the two cameras was evaluated in patients using QPS/QGS software for quantitative segmental perfusion, motion and thickness scores. RESULTS: The spatial resolution was identical with the two cameras. Count sensitivity of the DNM 670CZT was twofold lower compared with the DNM 530c, leading to lower sharpness index and contrast-to-noise ratio. The wall thickness and the myocardial volumes were similar. Visual and quantitative assessments of the perfusion patterns have shown a good concordance of the two cameras on phantoms and in patients. CONCLUSION: This study demonstrated the feasibility of myocardial perfusion SPECT imaging using the new whole-body DNM 670CZT camera. More... »

References to SciGraph publications

  • 2016-12. Left ventricular function assessment using 123I/99mTc dual-isotope acquisition with two semi-conductor cadmium–zinc–telluride (CZT) cameras: a gated cardiac phantom study in EJNMMI PHYSICS
  • 2010-12. Automatic and visual reproducibility of perfusion and function measures for myocardial perfusion SPECT in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2012-06. Impact of a new ultrafast CZT SPECT camera for myocardial perfusion imaging: fewer equivocal results and lower radiation dose in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2010-10. A fast cardiac gamma camera with dynamic SPECT capabilities: design, system validation and future potential in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2014-08. Importance of correct patient positioning in myocardial perfusion SPECT when using a CZT camera in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2010-04. Ultrafast nuclear myocardial perfusion imaging on a new gamma camera with semiconductor detector technique: first clinical validation in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2013-02. Comparison between stress myocardial perfusion SPECT recorded with cadmium-zinc-telluride and Anger cameras in various study protocols in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2017-12. CT-based SPECT attenuation correction and assessment of infarct size: results from a cardiac phantom study in ANNALS OF NUCLEAR MEDICINE
  • 2014-08. Segmental and global left ventricular function assessment using gated SPECT with a semiconductor Cadmium Zinc Telluride (CZT) camera: Phantom study and clinical validation vs cardiac magnetic resonance in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2013-01. Performance of a semiconductor SPECT system: comparison with a conventional Anger-type SPECT instrument in ANNALS OF NUCLEAR MEDICINE
  • 2015-11. First determination of the heart-to-mediastinum ratio using cardiac dual isotope (123I-MIBG/99mTc-tetrofosmin) CZT imaging in patients with heart failure: the ADRECARD study in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2011-10. Reduced isotope dose and imaging time with a high-efficiency CZT SPECT camera in JOURNAL OF NUCLEAR CARDIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12350-019-01702-2

    DOI

    http://dx.doi.org/10.1007/s12350-019-01702-2

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1113301151

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30963419


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