Incidence of atrioventricular block with vasodilator stress SPECT: A meta-analysis View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-10-17

AUTHORS

Efstathia Andrikopoulou, Charity J. Morgan, Lizbeth Brice, Navkaranbir S. Bajaj, Harish Doppalapudi, Ami E. Iskandrian, Fadi G. Hage

ABSTRACT

BackgroundAdenosine or regadenoson are often used with pharmacologic stress testing. Adenosine may trigger atrioventricular block (AVB). Despite its higher selectivity, regadenoson has also been associated with AVB. We studied the incidence of de novo AVB with these agents.MethodsA comprehensive search of SCOPUS was performed from inception to March 2016. Studies of at least 10 patients, using adenosine and/or regadenoson with SPECT-MPI, reporting rates of AVB were selected for further review.ResultsThirty four studies were pooled including 22,957 patients. Adenosine was used in 21 studies and regadenoson in 15. Both were administered in two studies. The estimated incidence of overall and high-grade AVB was 3.81% (95% CI 1.99%-6.19%) and 1.93% (95% CI 0.77%-3.59%), respectively. The incidence of AVB (8.58%; 95% CI 5.55%-12.21% vs 0.30%; 95% CI 0.04%-0.82%, respectively, P < .001) and high-grade AVB (5.21%; 95% CI 2.81%-8.30% vs 0.05%; 95% CI < .001%-0.19% respectively, P < .001) were higher with adenosine compared to regadenoson.ConclusionAVB is seen in about 4% of patients undergoing vasodilator stress test. Both overall and high-grade AVB are more frequent with adenosine compared to regadenoson. More... »

PAGES

616-628

References to SciGraph publications

  • 2012-12-11. Regadenoson: A focused update in JOURNAL OF NUCLEAR CARDIOLOGY
  • 1999-09. The safety of adenosine pharmacologic stress testing in patients with first-degree atrioventricular block in the presence and absence of atrioventricular blocking medications in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2012-12-12. Regadenoson pharmacologic stress for myocardial perfusion imaging: A three-way comparison between regadenoson administered at peak exercise, during walk recovery, or no-exercise in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2010-04-23. Lessons from regadenoson and low-level treadmill/regadenoson myocardial perfusion imaging: Initial clinical experience in 1263 patients in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2008-04-14. Safety of regadenoson, a selective adenosine A2A agonist, in patients with chronic obstructive pulmonary disease: A randomized, double-blind, placebo-controlled trial (RegCOPD trial) in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2006-09. Direct comparison of adenosine and adenosine 5-triphosphate as pharmacologic stress agents in conjunction with Tl-201 SPECT: Hemodynamic response, myocardial tracer uptake, and size of perfusion defects in the same subjects in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2011-12-27. Hemodynamic response, arrhythmic risk, and overall safety of Regadenoson as a pharmacologic stress agent for myocardial perfusion imaging in chronic obstructive pulmonary disease and bronchial asthma patients in THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
  • 2010-09-18. Safety of regadenoson in patients with end-stage liver disease in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2012-08-23. Complete heart block associated with regadenoson: A real side effect in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2012-12-11. Attenuation of the side effect profile of regadenoson: a randomized double-blind placebo-controlled study with aminophylline in patients undergoing myocardial perfusion imaging and have severe chronic kidney disease—the ASSUAGE-CKD trial in THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
  • 2011-05-04. Safety of regadenoson as a pharmacologic stress agent for myocardial perfusion imaging in chronic kidney disease patients not on hemodialysis in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2009-01-20. The RegEx trial: a randomized, double-blind, placebo- and active-controlled pilot study combining regadenoson, a selective A2A adenosine agonist, with low-level exercise, in patients undergoing myocardial perfusion imaging in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2012-03-07. Attenuation of the side effect profile of regadenoson: A randomized double-blinded placebo-controlled study with aminophylline in patients undergoing myocardial perfusion imaging. “The ASSUAGE trial” in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2014-08-23. Regadenoson-induced bradycardia and hypotension: Possible mechanism and antidote in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2012-04-07. A randomized, double-blind, placebo-controlled study assessing the safety and tolerability of regadenoson in subjects with asthma or chronic obstructive pulmonary disease in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2012-12-04. Safety and tolerability of regadenoson in 514 SPECT MPI patients with and without coronary artery disease and submaximal exercise heart rate response in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2013-02-13. Safety and feasibility of adjunctive regadenoson injection at peak exercise during exercise myocardial perfusion imaging: The Both Exercise and Regadenoson Stress Test (BERST) trial in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2016-02-25. ASNC imaging guidelines for SPECT nuclear cardiology procedures: Stress, protocols, and tracers in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2013-11-22. Regadenoson in Europe: first-year experience of regadenoson stress combined with submaximal exercise in patients undergoing myocardial perfusion scintigraphy in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2011-04-26. Development of asystole requiring cardiac resuscitation after the administration of regadenoson in a patient with pulmonary fibrosis receiving n-acetylcysteine in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2000-09. Treadmill exercise during adenosine infusion is safe, results in fewer adverse reactions, and improves myocardial perfusion image quality in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2010-02. Regadenoson in AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS
  • 2010-11-19. Safety of adenosine pharmacologic stress myocardial perfusion imaging in orthotopic cardiac transplant recipients: a single center experience of 102 transplant patients in THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
  • 2014-05-31. Asystole following regadenoson infusion in stable outpatients in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2014-06-19. Regadenoson for myocardial perfusion imaging: Is it safe? in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2016-12-20. Regadenoson-induced complete heart block and asystole: A real possibility nuclear laboratories should be aware of in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2007-09. Adenosine versus regadenoson comparative evaluation in myocardial perfusion imaging: Results of the ADVANCE phase 3 multicenter international trial in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2011-12-01. Selective adenosine agonists and myocardial perfusion imaging in JOURNAL OF NUCLEAR CARDIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12350-017-1081-y

    DOI

    http://dx.doi.org/10.1007/s12350-017-1081-y

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1092249469

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/29043556


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adenosine", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Atrioventricular Block", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Coronary Artery Disease", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Exercise Test", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Myocardial Perfusion Imaging", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Purines", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Pyrazoles", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Reproducibility of Results", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Tomography, Emission-Computed, Single-Photon", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Vasodilator Agents", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Brigham and Women\u2019s Hospital, Boston, MA, USA", 
              "id": "http://www.grid.ac/institutes/grid.62560.37", 
              "name": [
                "University of Alabama at Birmingham, Birmingham, AL, USA", 
                "Brigham and Women\u2019s Hospital, Boston, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Andrikopoulou", 
            "givenName": "Efstathia", 
            "id": "sg:person.01070062771.43", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070062771.43"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Alabama at Birmingham, Birmingham, AL, USA", 
              "id": "http://www.grid.ac/institutes/grid.265892.2", 
              "name": [
                "University of Alabama at Birmingham, Birmingham, AL, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Morgan", 
            "givenName": "Charity J.", 
            "id": "sg:person.011345144542.58", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011345144542.58"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Alabama at Birmingham, Birmingham, AL, USA", 
              "id": "http://www.grid.ac/institutes/grid.265892.2", 
              "name": [
                "University of Alabama at Birmingham, Birmingham, AL, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Brice", 
            "givenName": "Lizbeth", 
            "id": "sg:person.010467655543.12", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010467655543.12"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Brigham and Women\u2019s Hospital, Boston, MA, USA", 
              "id": "http://www.grid.ac/institutes/grid.62560.37", 
              "name": [
                "University of Alabama at Birmingham, Birmingham, AL, USA", 
                "Brigham and Women\u2019s Hospital, Boston, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bajaj", 
            "givenName": "Navkaranbir S.", 
            "id": "sg:person.01076674441.84", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076674441.84"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA", 
              "id": "http://www.grid.ac/institutes/grid.280808.a", 
              "name": [
                "University of Alabama at Birmingham, Birmingham, AL, USA", 
                "Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Doppalapudi", 
            "givenName": "Harish", 
            "id": "sg:person.01371576733.46", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371576733.46"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Alabama at Birmingham, Birmingham, AL, USA", 
              "id": "http://www.grid.ac/institutes/grid.265892.2", 
              "name": [
                "University of Alabama at Birmingham, Birmingham, AL, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Iskandrian", 
            "givenName": "Ami E.", 
            "id": "sg:person.011445705444.36", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011445705444.36"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA", 
              "id": "http://www.grid.ac/institutes/grid.280808.a", 
              "name": [
                "University of Alabama at Birmingham, Birmingham, AL, USA", 
                "Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hage", 
            "givenName": "Fadi G.", 
            "id": "sg:person.01031021335.98", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031021335.98"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/s12350-011-9378-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039335542", 
              "https://doi.org/10.1007/s12350-011-9378-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-012-9610-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001870773", 
              "https://doi.org/10.1007/s12350-012-9610-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10554-011-0003-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046316878", 
              "https://doi.org/10.1007/s10554-011-0003-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1016/s1071-3581(99)90021-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013279435", 
              "https://doi.org/10.1016/s1071-3581(99)90021-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00259-012-2296-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036034749", 
              "https://doi.org/10.1007/s00259-012-2296-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-014-9968-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019223837", 
              "https://doi.org/10.1007/s12350-014-9968-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-014-9922-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017732048", 
              "https://doi.org/10.1007/s12350-014-9922-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-016-0755-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016140989", 
              "https://doi.org/10.1007/s12350-016-0755-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-008-9001-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029137041", 
              "https://doi.org/10.1007/s12350-008-9001-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10554-010-9749-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030564501", 
              "https://doi.org/10.1007/s10554-010-9749-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-011-9373-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021594276", 
              "https://doi.org/10.1007/s12350-011-9373-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-015-0387-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053436751", 
              "https://doi.org/10.1007/s12350-015-0387-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.2165/10489040-000000000-00000", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021170549", 
              "https://doi.org/10.2165/10489040-000000000-00000"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-013-9679-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017809544", 
              "https://doi.org/10.1007/s12350-013-9679-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1067/mnc.2000.108030", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042617503", 
              "https://doi.org/10.1067/mnc.2000.108030"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1016/j.nuclcard.2008.02.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030937009", 
              "https://doi.org/10.1016/j.nuclcard.2008.02.013"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1016/j.nuclcard.2007.06.114", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035693866", 
              "https://doi.org/10.1016/j.nuclcard.2007.06.114"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-011-9474-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026731210", 
              "https://doi.org/10.1007/s12350-011-9474-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1016/j.nuclcard.2006.05.021", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020996663", 
              "https://doi.org/10.1016/j.nuclcard.2006.05.021"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-014-9898-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008563323", 
              "https://doi.org/10.1007/s12350-014-9898-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10554-012-0166-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038409386", 
              "https://doi.org/10.1007/s10554-012-0166-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-012-9533-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046736189", 
              "https://doi.org/10.1007/s12350-012-9533-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-010-9229-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005119673", 
              "https://doi.org/10.1007/s12350-010-9229-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00259-013-2619-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009089281", 
              "https://doi.org/10.1007/s00259-013-2619-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-012-9547-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002414779", 
              "https://doi.org/10.1007/s12350-012-9547-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-010-9288-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030409482", 
              "https://doi.org/10.1007/s12350-010-9288-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-012-9661-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015262021", 
              "https://doi.org/10.1007/s12350-012-9661-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12350-012-9660-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029508554", 
              "https://doi.org/10.1007/s12350-012-9660-4"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2017-10-17", 
        "datePublishedReg": "2017-10-17", 
        "description": "BackgroundAdenosine or regadenoson are often used with pharmacologic stress testing. Adenosine may trigger atrioventricular block (AVB). Despite its higher selectivity, regadenoson has also been associated with AVB. We studied the incidence of de novo AVB with these agents.MethodsA comprehensive search of SCOPUS was performed from inception to March 2016. Studies of at least 10 patients, using adenosine and/or regadenoson with SPECT-MPI, reporting rates of AVB were selected for further review.ResultsThirty four studies were pooled including 22,957 patients. Adenosine was used in 21 studies and regadenoson in 15. Both were administered in two studies. The estimated incidence of overall and high-grade AVB was 3.81% (95% CI 1.99%-6.19%) and 1.93% (95% CI 0.77%-3.59%), respectively. The incidence of AVB (8.58%; 95% CI 5.55%-12.21% vs 0.30%; 95% CI 0.04%-0.82%, respectively, P\u00a0<\u00a0.001) and high-grade AVB (5.21%; 95% CI 2.81%-8.30% vs 0.05%; 95% CI\u00a0<\u00a0.001%-0.19% respectively, P\u00a0<\u00a0.001) were higher with adenosine compared to regadenoson.ConclusionAVB is seen in about 4% of patients undergoing vasodilator stress test. Both overall and high-grade AVB are more frequent with adenosine compared to regadenoson.", 
        "genre": "article", 
        "id": "sg:pub.10.1007/s12350-017-1081-y", 
        "inLanguage": "en", 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2684991", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1106202", 
            "issn": [
              "1071-3581", 
              "1532-6551"
            ], 
            "name": "Journal of Nuclear Cardiology", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "2", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "26"
          }
        ], 
        "keywords": [
          "high-grade atrioventricular block", 
          "atrioventricular block", 
          "incidence of AVB", 
          "vasodilator stress test", 
          "pharmacologic stress testing", 
          "SPECT-MPI", 
          "stress SPECT", 
          "regadenoson", 
          "comprehensive search", 
          "patients", 
          "incidence", 
          "stress testing", 
          "further review", 
          "stress test", 
          "adenosine", 
          "study", 
          "SPECT", 
          "Scopus", 
          "review", 
          "agents", 
          "testing", 
          "inception", 
          "rate", 
          "test", 
          "block", 
          "search", 
          "selectivity", 
          "high selectivity", 
          "BackgroundAdenosine", 
          "de novo AVB", 
          "novo AVB", 
          "rates of AVB", 
          "ConclusionAVB", 
          "vasodilator stress SPECT"
        ], 
        "name": "Incidence of atrioventricular block with vasodilator stress SPECT: A meta-analysis", 
        "pagination": "616-628", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1092249469"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s12350-017-1081-y"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "29043556"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s12350-017-1081-y", 
          "https://app.dimensions.ai/details/publication/pub.1092249469"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2021-11-01T18:30", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_733.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1007/s12350-017-1081-y"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12350-017-1081-y'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12350-017-1081-y'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12350-017-1081-y'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12350-017-1081-y'


     

    This table displays all metadata directly associated to this object as RDF triples.

    320 TRIPLES      22 PREDICATES      103 URIs      67 LITERALS      22 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s12350-017-1081-y schema:about N035fb9b2d3854b21b8fe6564fd00720c
    2 N1a5a9237bd24467dbbb469f00debf0eb
    3 N1c21a181ece74d8faa7d0f9cc1a75251
    4 N2deb14126c104cb29d39f88ec0fd613c
    5 N4168172fdde94067b44ec710a095543f
    6 N4267008da9d441728850ffe3f4961ace
    7 N4af9e94e065a4f8dbc45a8d7ad5ced8e
    8 N5c9232e6f8e0440689f1603220385ea5
    9 N7b72d85e655847b69fee24c6e0783a07
    10 Naa548657486c4ff18051a798373b656b
    11 Nc12e0a3b74a54eb89c5720fe212573cb
    12 Nc895c54dbe6942f5af7cfd41de5b2231
    13 Nd2d18258f67341be83f19732d58bf180
    14 Nd344c4fe50a547a7b2fa4db561b83d0f
    15 Nd71ef4a91ecf4d14a7786ec02740de65
    16 anzsrc-for:11
    17 anzsrc-for:1103
    18 schema:author N4a6aeb220eb94749b5b2986097bec05f
    19 schema:citation sg:pub.10.1007/s00259-012-2296-4
    20 sg:pub.10.1007/s00259-013-2619-0
    21 sg:pub.10.1007/s10554-010-9749-2
    22 sg:pub.10.1007/s10554-011-0003-3
    23 sg:pub.10.1007/s10554-012-0166-6
    24 sg:pub.10.1007/s12350-008-9001-9
    25 sg:pub.10.1007/s12350-010-9229-z
    26 sg:pub.10.1007/s12350-010-9288-1
    27 sg:pub.10.1007/s12350-011-9373-0
    28 sg:pub.10.1007/s12350-011-9378-8
    29 sg:pub.10.1007/s12350-011-9474-9
    30 sg:pub.10.1007/s12350-012-9533-x
    31 sg:pub.10.1007/s12350-012-9547-4
    32 sg:pub.10.1007/s12350-012-9610-1
    33 sg:pub.10.1007/s12350-012-9660-4
    34 sg:pub.10.1007/s12350-012-9661-3
    35 sg:pub.10.1007/s12350-013-9679-1
    36 sg:pub.10.1007/s12350-014-9898-0
    37 sg:pub.10.1007/s12350-014-9922-4
    38 sg:pub.10.1007/s12350-014-9968-3
    39 sg:pub.10.1007/s12350-015-0387-x
    40 sg:pub.10.1007/s12350-016-0755-1
    41 sg:pub.10.1016/j.nuclcard.2006.05.021
    42 sg:pub.10.1016/j.nuclcard.2007.06.114
    43 sg:pub.10.1016/j.nuclcard.2008.02.013
    44 sg:pub.10.1016/s1071-3581(99)90021-1
    45 sg:pub.10.1067/mnc.2000.108030
    46 sg:pub.10.2165/10489040-000000000-00000
    47 schema:datePublished 2017-10-17
    48 schema:datePublishedReg 2017-10-17
    49 schema:description BackgroundAdenosine or regadenoson are often used with pharmacologic stress testing. Adenosine may trigger atrioventricular block (AVB). Despite its higher selectivity, regadenoson has also been associated with AVB. We studied the incidence of de novo AVB with these agents.MethodsA comprehensive search of SCOPUS was performed from inception to March 2016. Studies of at least 10 patients, using adenosine and/or regadenoson with SPECT-MPI, reporting rates of AVB were selected for further review.ResultsThirty four studies were pooled including 22,957 patients. Adenosine was used in 21 studies and regadenoson in 15. Both were administered in two studies. The estimated incidence of overall and high-grade AVB was 3.81% (95% CI 1.99%-6.19%) and 1.93% (95% CI 0.77%-3.59%), respectively. The incidence of AVB (8.58%; 95% CI 5.55%-12.21% vs 0.30%; 95% CI 0.04%-0.82%, respectively, P < .001) and high-grade AVB (5.21%; 95% CI 2.81%-8.30% vs 0.05%; 95% CI < .001%-0.19% respectively, P < .001) were higher with adenosine compared to regadenoson.ConclusionAVB is seen in about 4% of patients undergoing vasodilator stress test. Both overall and high-grade AVB are more frequent with adenosine compared to regadenoson.
    50 schema:genre article
    51 schema:inLanguage en
    52 schema:isAccessibleForFree true
    53 schema:isPartOf N67115ab68e37440a8c9d4c4e16ae073d
    54 Ndeaaeb1ecbd041f0a4df4c38cc12a0b9
    55 sg:journal.1106202
    56 schema:keywords BackgroundAdenosine
    57 ConclusionAVB
    58 SPECT
    59 SPECT-MPI
    60 Scopus
    61 adenosine
    62 agents
    63 atrioventricular block
    64 block
    65 comprehensive search
    66 de novo AVB
    67 further review
    68 high selectivity
    69 high-grade atrioventricular block
    70 inception
    71 incidence
    72 incidence of AVB
    73 novo AVB
    74 patients
    75 pharmacologic stress testing
    76 rate
    77 rates of AVB
    78 regadenoson
    79 review
    80 search
    81 selectivity
    82 stress SPECT
    83 stress test
    84 stress testing
    85 study
    86 test
    87 testing
    88 vasodilator stress SPECT
    89 vasodilator stress test
    90 schema:name Incidence of atrioventricular block with vasodilator stress SPECT: A meta-analysis
    91 schema:pagination 616-628
    92 schema:productId N3c7f97c6de834c6a94f1d2bacd4083f6
    93 N6a1016b21fb14335b2052d6d332d009f
    94 Nfa16fd8d8afe45b1a52c9003cd24e763
    95 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092249469
    96 https://doi.org/10.1007/s12350-017-1081-y
    97 schema:sdDatePublished 2021-11-01T18:30
    98 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    99 schema:sdPublisher N5c9319a3c96b42d589e17710bcf10a6d
    100 schema:url https://doi.org/10.1007/s12350-017-1081-y
    101 sgo:license sg:explorer/license/
    102 sgo:sdDataset articles
    103 rdf:type schema:ScholarlyArticle
    104 N035fb9b2d3854b21b8fe6564fd00720c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    105 schema:name Male
    106 rdf:type schema:DefinedTerm
    107 N19672cdfd4e34f47af49b7fc3dfccebe rdf:first sg:person.01371576733.46
    108 rdf:rest N73ce1ca290ff448e9344709634c0d17a
    109 N1a5a9237bd24467dbbb469f00debf0eb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    110 schema:name Middle Aged
    111 rdf:type schema:DefinedTerm
    112 N1c21a181ece74d8faa7d0f9cc1a75251 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    113 schema:name Myocardial Perfusion Imaging
    114 rdf:type schema:DefinedTerm
    115 N2b230e8444184ff3a38d2b888db9354d rdf:first sg:person.01076674441.84
    116 rdf:rest N19672cdfd4e34f47af49b7fc3dfccebe
    117 N2deb14126c104cb29d39f88ec0fd613c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    118 schema:name Reproducibility of Results
    119 rdf:type schema:DefinedTerm
    120 N316a95cc97ac4c5e85ef1d3a97d441e3 rdf:first sg:person.010467655543.12
    121 rdf:rest N2b230e8444184ff3a38d2b888db9354d
    122 N3c7f97c6de834c6a94f1d2bacd4083f6 schema:name pubmed_id
    123 schema:value 29043556
    124 rdf:type schema:PropertyValue
    125 N4168172fdde94067b44ec710a095543f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    126 schema:name Purines
    127 rdf:type schema:DefinedTerm
    128 N4267008da9d441728850ffe3f4961ace schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    129 schema:name Vasodilator Agents
    130 rdf:type schema:DefinedTerm
    131 N4a6aeb220eb94749b5b2986097bec05f rdf:first sg:person.01070062771.43
    132 rdf:rest Nca321a6a019440899cda06376a5e6ee2
    133 N4af9e94e065a4f8dbc45a8d7ad5ced8e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    134 schema:name Female
    135 rdf:type schema:DefinedTerm
    136 N5c9232e6f8e0440689f1603220385ea5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    137 schema:name Coronary Artery Disease
    138 rdf:type schema:DefinedTerm
    139 N5c9319a3c96b42d589e17710bcf10a6d schema:name Springer Nature - SN SciGraph project
    140 rdf:type schema:Organization
    141 N67115ab68e37440a8c9d4c4e16ae073d schema:issueNumber 2
    142 rdf:type schema:PublicationIssue
    143 N6a1016b21fb14335b2052d6d332d009f schema:name dimensions_id
    144 schema:value pub.1092249469
    145 rdf:type schema:PropertyValue
    146 N73ce1ca290ff448e9344709634c0d17a rdf:first sg:person.011445705444.36
    147 rdf:rest Nc26525370cbe42cda247046b2272821f
    148 N7b72d85e655847b69fee24c6e0783a07 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    149 schema:name Pyrazoles
    150 rdf:type schema:DefinedTerm
    151 Naa548657486c4ff18051a798373b656b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    152 schema:name Tomography, Emission-Computed, Single-Photon
    153 rdf:type schema:DefinedTerm
    154 Nc12e0a3b74a54eb89c5720fe212573cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    155 schema:name Humans
    156 rdf:type schema:DefinedTerm
    157 Nc26525370cbe42cda247046b2272821f rdf:first sg:person.01031021335.98
    158 rdf:rest rdf:nil
    159 Nc895c54dbe6942f5af7cfd41de5b2231 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    160 schema:name Exercise Test
    161 rdf:type schema:DefinedTerm
    162 Nca321a6a019440899cda06376a5e6ee2 rdf:first sg:person.011345144542.58
    163 rdf:rest N316a95cc97ac4c5e85ef1d3a97d441e3
    164 Nd2d18258f67341be83f19732d58bf180 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    165 schema:name Adenosine
    166 rdf:type schema:DefinedTerm
    167 Nd344c4fe50a547a7b2fa4db561b83d0f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    168 schema:name Atrioventricular Block
    169 rdf:type schema:DefinedTerm
    170 Nd71ef4a91ecf4d14a7786ec02740de65 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    171 schema:name Aged
    172 rdf:type schema:DefinedTerm
    173 Ndeaaeb1ecbd041f0a4df4c38cc12a0b9 schema:volumeNumber 26
    174 rdf:type schema:PublicationVolume
    175 Nfa16fd8d8afe45b1a52c9003cd24e763 schema:name doi
    176 schema:value 10.1007/s12350-017-1081-y
    177 rdf:type schema:PropertyValue
    178 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    179 schema:name Medical and Health Sciences
    180 rdf:type schema:DefinedTerm
    181 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    182 schema:name Clinical Sciences
    183 rdf:type schema:DefinedTerm
    184 sg:grant.2684991 http://pending.schema.org/fundedItem sg:pub.10.1007/s12350-017-1081-y
    185 rdf:type schema:MonetaryGrant
    186 sg:journal.1106202 schema:issn 1071-3581
    187 1532-6551
    188 schema:name Journal of Nuclear Cardiology
    189 schema:publisher Springer Nature
    190 rdf:type schema:Periodical
    191 sg:person.01031021335.98 schema:affiliation grid-institutes:grid.280808.a
    192 schema:familyName Hage
    193 schema:givenName Fadi G.
    194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031021335.98
    195 rdf:type schema:Person
    196 sg:person.010467655543.12 schema:affiliation grid-institutes:grid.265892.2
    197 schema:familyName Brice
    198 schema:givenName Lizbeth
    199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010467655543.12
    200 rdf:type schema:Person
    201 sg:person.01070062771.43 schema:affiliation grid-institutes:grid.62560.37
    202 schema:familyName Andrikopoulou
    203 schema:givenName Efstathia
    204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070062771.43
    205 rdf:type schema:Person
    206 sg:person.01076674441.84 schema:affiliation grid-institutes:grid.62560.37
    207 schema:familyName Bajaj
    208 schema:givenName Navkaranbir S.
    209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076674441.84
    210 rdf:type schema:Person
    211 sg:person.011345144542.58 schema:affiliation grid-institutes:grid.265892.2
    212 schema:familyName Morgan
    213 schema:givenName Charity J.
    214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011345144542.58
    215 rdf:type schema:Person
    216 sg:person.011445705444.36 schema:affiliation grid-institutes:grid.265892.2
    217 schema:familyName Iskandrian
    218 schema:givenName Ami E.
    219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011445705444.36
    220 rdf:type schema:Person
    221 sg:person.01371576733.46 schema:affiliation grid-institutes:grid.280808.a
    222 schema:familyName Doppalapudi
    223 schema:givenName Harish
    224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371576733.46
    225 rdf:type schema:Person
    226 sg:pub.10.1007/s00259-012-2296-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036034749
    227 https://doi.org/10.1007/s00259-012-2296-4
    228 rdf:type schema:CreativeWork
    229 sg:pub.10.1007/s00259-013-2619-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009089281
    230 https://doi.org/10.1007/s00259-013-2619-0
    231 rdf:type schema:CreativeWork
    232 sg:pub.10.1007/s10554-010-9749-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030564501
    233 https://doi.org/10.1007/s10554-010-9749-2
    234 rdf:type schema:CreativeWork
    235 sg:pub.10.1007/s10554-011-0003-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046316878
    236 https://doi.org/10.1007/s10554-011-0003-3
    237 rdf:type schema:CreativeWork
    238 sg:pub.10.1007/s10554-012-0166-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038409386
    239 https://doi.org/10.1007/s10554-012-0166-6
    240 rdf:type schema:CreativeWork
    241 sg:pub.10.1007/s12350-008-9001-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029137041
    242 https://doi.org/10.1007/s12350-008-9001-9
    243 rdf:type schema:CreativeWork
    244 sg:pub.10.1007/s12350-010-9229-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1005119673
    245 https://doi.org/10.1007/s12350-010-9229-z
    246 rdf:type schema:CreativeWork
    247 sg:pub.10.1007/s12350-010-9288-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030409482
    248 https://doi.org/10.1007/s12350-010-9288-1
    249 rdf:type schema:CreativeWork
    250 sg:pub.10.1007/s12350-011-9373-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021594276
    251 https://doi.org/10.1007/s12350-011-9373-0
    252 rdf:type schema:CreativeWork
    253 sg:pub.10.1007/s12350-011-9378-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039335542
    254 https://doi.org/10.1007/s12350-011-9378-8
    255 rdf:type schema:CreativeWork
    256 sg:pub.10.1007/s12350-011-9474-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026731210
    257 https://doi.org/10.1007/s12350-011-9474-9
    258 rdf:type schema:CreativeWork
    259 sg:pub.10.1007/s12350-012-9533-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1046736189
    260 https://doi.org/10.1007/s12350-012-9533-x
    261 rdf:type schema:CreativeWork
    262 sg:pub.10.1007/s12350-012-9547-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002414779
    263 https://doi.org/10.1007/s12350-012-9547-4
    264 rdf:type schema:CreativeWork
    265 sg:pub.10.1007/s12350-012-9610-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001870773
    266 https://doi.org/10.1007/s12350-012-9610-1
    267 rdf:type schema:CreativeWork
    268 sg:pub.10.1007/s12350-012-9660-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029508554
    269 https://doi.org/10.1007/s12350-012-9660-4
    270 rdf:type schema:CreativeWork
    271 sg:pub.10.1007/s12350-012-9661-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015262021
    272 https://doi.org/10.1007/s12350-012-9661-3
    273 rdf:type schema:CreativeWork
    274 sg:pub.10.1007/s12350-013-9679-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017809544
    275 https://doi.org/10.1007/s12350-013-9679-1
    276 rdf:type schema:CreativeWork
    277 sg:pub.10.1007/s12350-014-9898-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008563323
    278 https://doi.org/10.1007/s12350-014-9898-0
    279 rdf:type schema:CreativeWork
    280 sg:pub.10.1007/s12350-014-9922-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017732048
    281 https://doi.org/10.1007/s12350-014-9922-4
    282 rdf:type schema:CreativeWork
    283 sg:pub.10.1007/s12350-014-9968-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019223837
    284 https://doi.org/10.1007/s12350-014-9968-3
    285 rdf:type schema:CreativeWork
    286 sg:pub.10.1007/s12350-015-0387-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1053436751
    287 https://doi.org/10.1007/s12350-015-0387-x
    288 rdf:type schema:CreativeWork
    289 sg:pub.10.1007/s12350-016-0755-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016140989
    290 https://doi.org/10.1007/s12350-016-0755-1
    291 rdf:type schema:CreativeWork
    292 sg:pub.10.1016/j.nuclcard.2006.05.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020996663
    293 https://doi.org/10.1016/j.nuclcard.2006.05.021
    294 rdf:type schema:CreativeWork
    295 sg:pub.10.1016/j.nuclcard.2007.06.114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035693866
    296 https://doi.org/10.1016/j.nuclcard.2007.06.114
    297 rdf:type schema:CreativeWork
    298 sg:pub.10.1016/j.nuclcard.2008.02.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030937009
    299 https://doi.org/10.1016/j.nuclcard.2008.02.013
    300 rdf:type schema:CreativeWork
    301 sg:pub.10.1016/s1071-3581(99)90021-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013279435
    302 https://doi.org/10.1016/s1071-3581(99)90021-1
    303 rdf:type schema:CreativeWork
    304 sg:pub.10.1067/mnc.2000.108030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042617503
    305 https://doi.org/10.1067/mnc.2000.108030
    306 rdf:type schema:CreativeWork
    307 sg:pub.10.2165/10489040-000000000-00000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021170549
    308 https://doi.org/10.2165/10489040-000000000-00000
    309 rdf:type schema:CreativeWork
    310 grid-institutes:grid.265892.2 schema:alternateName University of Alabama at Birmingham, Birmingham, AL, USA
    311 schema:name University of Alabama at Birmingham, Birmingham, AL, USA
    312 rdf:type schema:Organization
    313 grid-institutes:grid.280808.a schema:alternateName Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA
    314 schema:name Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA
    315 University of Alabama at Birmingham, Birmingham, AL, USA
    316 rdf:type schema:Organization
    317 grid-institutes:grid.62560.37 schema:alternateName Brigham and Women’s Hospital, Boston, MA, USA
    318 schema:name Brigham and Women’s Hospital, Boston, MA, USA
    319 University of Alabama at Birmingham, Birmingham, AL, USA
    320 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...