Advances in imaging instrumentation for nuclear cardiology View Full Text


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Article Info

DATE

2017-07-17

AUTHORS

Jae Sung Lee, Gil Kovalski, Tali Sharir, Dong Soo Lee

ABSTRACT

Advances in imaging instrumentation and technology have greatly contributed to nuclear cardiology. Dedicated cardiac SPECT cameras incorporating novel, highly efficient detector, collimator, and system designs have emerged with the expansion of nuclear cardiology. Solid-state radiation detectors incorporating cadmium zinc telluride, which directly convert radiation to electrical signals and yield improved energy resolution and spatial resolution and enhanced count sensitivity geometries, are increasingly gaining favor as the detector of choice for application in dedicated cardiac SPECT systems. Additionally, hybrid imaging systems in which SPECT and PET are combined with X-ray CT are currently widely used, with PET/MRI hybrid systems having also been recently introduced. The improved quantitative SPECT/CT has the potential to measure the absolute quantification of myocardial blood flow and flow reserve. Rapid development of silicon photomultipliers leads to enhancement in PET image quality and count rates. In addition, the reduction of emission–transmission mismatch artifacts via application of accurate time-of-flight information, and cardiac motion de-blurring aided by anatomical images, are emerging techniques for further improvement of cardiac PET. This article reviews recent advances such as these in nuclear cardiology imaging instrumentation and technology, and the corresponding diagnostic benefits. More... »

PAGES

543-556

References to SciGraph publications

  • 2015-04-14. Precision and accuracy of clinical quantification of myocardial blood flow by dynamic PET: A technical perspective in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2014-10-09. Absolute myocardial blood flow quantification with SPECT/CT: Is it possible? in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2016-07-13. Recent Advances in Nuclear Cardiology in NUCLEAR MEDICINE AND MOLECULAR IMAGING
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  • 2015-02-20. Feasibility of [18F]-RGD for ex vivo imaging of atherosclerosis in detection of αvβ3 integrin expression in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2015-05-27. Comparison of the diagnostic accuracies of very low stress-dose with standard-dose myocardial perfusion imaging: Automated quantification of one-day, stress-first SPECT using a CZT camera in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2009-08-18. Novel solid-state-detector dedicated cardiac camera for fast myocardial perfusion imaging: multicenter comparison with standard dual detector cameras in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2015-07-02. Comparative analysis of cadmium-zincum-telluride cameras dedicated to myocardial perfusion SPECT: A phantom study in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2007-07. Clinical results of a novel wide beam reconstruction method for shortening scan time of Tc-99m cardiac SPECT perfusion studies in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2014-08-21. Quantitation of myocardial blood flow and myocardial flow reserve with 99mTc-sestamibi dynamic SPECT/CT to enhance detection of coronary artery disease in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2014-10-14. Are SPECT measurements of myocardial blood flow and flow reserve ready for clinical use? in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2016-02-16. Recent developments in time-of-flight PET in EJNMMI PHYSICS
  • 2016-01-26. PET/MRI: Technical Challenges and Recent Advances in NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2013-06-05. High-efficiency SPECT MPI: Comparison of automated quantification, visual interpretation, and coronary angiography in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2010-06-29. A fast cardiac gamma camera with dynamic SPECT capabilities: design, system validation and future potential in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2009-01-22. Dual “motion-frozen heart” combining respiration and contraction compensation in clinical myocardial perfusion SPECT imaging in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2015-08-15. Simultaneous reconstruction of attenuation and activity in cardiac PET can remove CT misalignment artifacts in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2016-02-22. Instrumentation for Time-of-Flight Positron Emission Tomography in NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2014-10-04. Feasibility and operator variability of myocardial blood flow and reserve measurements with 99mTc-sestamibi quantitative dynamic SPECT/CT imaging in JOURNAL OF NUCLEAR CARDIOLOGY
  • 2013-12-07. The influence of coronary calcium score on the interpretation of myocardial perfusion imaging in JOURNAL OF NUCLEAR CARDIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12350-017-0979-8

    DOI

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    48 schema:description Advances in imaging instrumentation and technology have greatly contributed to nuclear cardiology. Dedicated cardiac SPECT cameras incorporating novel, highly efficient detector, collimator, and system designs have emerged with the expansion of nuclear cardiology. Solid-state radiation detectors incorporating cadmium zinc telluride, which directly convert radiation to electrical signals and yield improved energy resolution and spatial resolution and enhanced count sensitivity geometries, are increasingly gaining favor as the detector of choice for application in dedicated cardiac SPECT systems. Additionally, hybrid imaging systems in which SPECT and PET are combined with X-ray CT are currently widely used, with PET/MRI hybrid systems having also been recently introduced. The improved quantitative SPECT/CT has the potential to measure the absolute quantification of myocardial blood flow and flow reserve. Rapid development of silicon photomultipliers leads to enhancement in PET image quality and count rates. In addition, the reduction of emission–transmission mismatch artifacts via application of accurate time-of-flight information, and cardiac motion de-blurring aided by anatomical images, are emerging techniques for further improvement of cardiac PET. This article reviews recent advances such as these in nuclear cardiology imaging instrumentation and technology, and the corresponding diagnostic benefits.
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