Dual gated PET/CT imaging of small targets of the heart: Method description and testing with a dynamic heart phantom View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-11-18

AUTHORS

Tommi Kokki, Hannu T. Sipilä, Mika Teräs, Tommi Noponen, Nicolas Durand-Schaefer, Riku Klén, Juhani Knuuti

ABSTRACT

BackgroundIn PET imaging respiratory and cardiac contraction motions interfere the imaging of heart. The aim was to develop and evaluate dual gating method for improving the detection of small targets of the heart.MethodsThe method utilizes two independent triggers which are sent periodically into list mode data based on respiratory and ECG cycles. An algorithm for generating dual gated segments from list mode data was developed.ResultsThe test measurements showed that rotational and axial movements of point source can be separated spatially to different segments with well-defined borders. The effect of dual gating on detection of small moving targets was tested with a moving heart phantom. Dual gated images showed 51% elimination (3.6 mm out of 7.0 mm) of contraction motion of hot spot (diameter 3 mm) and 70% elimination (14 mm out of 20 mm) of respiratory motion. Averaged activity value of hot spot increases by 89% when comparing to non-gated images. Patient study of suspected cardiac sarcoidosis shows sharper spatial myocardial uptake profile and improved detection of small myocardial structures such as papillary muscles.ConclusionsThe dual gating method improves detection of small moving targets in a phantom and it is feasible in clinical situations. More... »

PAGES

71-84

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12350-009-9163-0

DOI

http://dx.doi.org/10.1007/s12350-009-9163-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1052289628

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19921533


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