Novel solid-state-detector dedicated cardiac camera for fast myocardial perfusion imaging: multicenter comparison with standard dual detector cameras View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-08-18

AUTHORS

Fabio P. Esteves, Paolo Raggi, Russell D. Folks, Zohar Keidar, J. Wells Askew, Shmuel Rispler, Michael K. O’Connor, Liudmilla Verdes, Ernest V. Garcia

ABSTRACT

ObjectiveTo compare the diagnostic performance of a new dedicated ultrafast solid-state cardiac camera (Discovery NM 530c [DNM]) with standard dual detector cameras (S-SPECT) in myocardial perfusion imaging. The primary goal was a per-patient analysis of diagnostic performance of the DNM using S-SPECT as the reference standard.Methods and resultsIn total, 168 patients underwent one-day Tc-99m tetrofosmin rest/stress myocardial perfusion SPECT. DNM and S-SPECT images were obtained with the same injected doses. The DNM camera uses an array of cadmium zinc telluride pixilated detectors and a multipinhole collimator simultaneously imaging all cardiac views with no moving parts. Rest and stress acquisition times were 4 and 2 minutes for DNM and 14 and 12 minutes for S-SPECT. Two blinded readers independently interpreted all scans on a patient level and on a vascular territory level using a standard five-point scale. Interobserver differences were resolved by a third observer. Agreement between DNM and S-SPECT for presence or absence of myocardial perfusion defects on a per-patient analysis was 91.9% and 92.5%, respectively. Correlation coefficients of rest and stress left ventricular ejection fractions were 0.87 (P < .01) and 0.90 (P < .01).ConclusionThe diagnostic performance of DNM is comparable to that of S-SPECT on a per-patient basis. However, superior image quality can be achieved with significantly shorter acquisition times with DNM because of improved count sensitivity and image contrast over S-SPECT. More... »

PAGES

927

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12350-009-9137-2

DOI

http://dx.doi.org/10.1007/s12350-009-9137-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1004940899

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19688410


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