Ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-09

AUTHORS

Celine Terrada, Benedicte Neven, Nathalie Boddaert, Eric H Souied, Anne Marie Prieur, Pierre Quartier, Phuc Lehoang, Bahram Bodaghi

ABSTRACT

An 8-year-old patient with genetically confirmed chronic infantile neurological cutaneous and articular syndrome was treated with interleukin-1 receptor antagonist, anakinra. She initially presented with recurrent episodes of fever, rash, chronic fatigue, frequent headaches, ocular involvement (corneal infiltrate and papillary edema), and permanent increased biologic inflammatory markers. Following treatment with anakinra, all symptoms and inflammation resolved. Ophthalmologic signs normalized. This ophthalmologic description (optic nerve and cornea) has never been illustrated, even if ocular affections are classic in the cryopyrin-associated periodic syndromes. More... »

PAGES

133-136

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12348-010-0018-2

DOI

http://dx.doi.org/10.1007/s12348-010-0018-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1051567963

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21484180


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