Visceral disseminated varicella-zoster virus infection in an immunocompetent host View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2022-03-02

AUTHORS

Yasumasa Matsuo, Yosuke Igarashi, Natsumi Aoyama, Yosuke Satta, Ritsuko Oikawa, Yohei Noguchi, Hideaki Takahashi, Nobuyuki Matsumoto, Hiroyuki Yamamoto, Fumio Itoh

ABSTRACT

Varicella-zoster virus (VZV) can cause visceral disseminated VZV infection in immunocompromised patients. We experienced visceral disseminated VZV infection in an immunocompetent host. A 78-year-old woman visited our hospital complaining of abdominal pain that had persisted for 7 days. On day 3 after admission, a skin rash with blisters appeared mainly on her head and trunk that was diagnosed as generalized zoster via rapid skin VZV diagnostic kit. Esophagogastroduodenoscopy showed gastric erosions, and VZV was detected by real-time polymerase chain reaction testing of the gastric mucosal biopsy specimen. Computed tomography imaging also revealed pancreatitis and colitis, and she was diagnosed as having visceral disseminated VZV infection involving multiple organs. She was treated with acyclovir intravenously, after which her skin rash and abdominal pain disappeared. Because visceral disseminated VZV infection can occur in immunocompetent patients, this disease should be considered in patients with unexplained inflammatory lesions of the gastrointestinal tract or pancreas. More... »

PAGES

568-574

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12328-022-01607-7

DOI

http://dx.doi.org/10.1007/s12328-022-01607-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1145980831

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/35235151


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