A case of gastric signet-ring cell carcinoma with a long-term retrospective follow-up of 17 years View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2021-07-22

AUTHORS

Junichi Muraishi, Masaki Miyaoka, Kentaro Imamura, Kensei Ohtsu, Takao Kanemitsu, Ken Kinjo, Toshiharu Ueki, Hiroshi Tanabe, Seiji Haraoka, Satoshi Nimura, Akinori Iwashita, Kenshi Yao

ABSTRACT

A man in his 60s underwent esophagogastroduodenoscopy (EGD) for gastric cancer screening in 2006. A pale, oval, depressed lesion, 8 mm in diameter, was seen in the greater curvature of the gastric antrum. The patient was followed up every 1–2 years. EGD performed 13 years after 2006 showed the lesion with an irregular margin. Histopathological diagnosis of a target biopsy was signet-ring cell carcinoma. The lesion was resected by endoscopic submucosal dissection. The resected specimen was 8 × 3 mm in size, and histopathological examination showed type 0-IIc, signet-ring cell carcinoma, pT1a, Ly0, V0, UL0, pHM0, pVM0. The patient had no history of Helicobacter pylori infection. The serum anti-H. pylori IgG antibody test result and the urea breath test result was negative. Histopathological examination did not reveal the presence of H. pylori. No evidence of atrophic gastritis on endoscopy was found. Based on these findings, the patient was confirmed as not having H. pylori infection. We retrospectively reviewed all previous endoscopic images and confirmed that the lesion was already present in the images taken 17 years ago. To our knowledge, this is the longest retrospective follow-up (17 years) of gastric signet-ring cell carcinoma remaining in the mucosa, without H. pylori infection. More... »

PAGES

1337-1343

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12328-021-01443-1

DOI

http://dx.doi.org/10.1007/s12328-021-01443-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1139863730

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/34296396


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