Update zur Extrakorporalen Photopherese View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2021-10-05

AUTHORS

R. Knobler, T. Valero, U. Just

ABSTRACT

More than 30 years ago, ECP (extracorporeal photochemotherapy) was developed for the treatment of refractory cutaneous T‑cell lymphomas (CTCL), in particular Sézary syndrome. R. Edelson combined leukapheresis with photochemotherapy, where cells of the peripheral blood are irradiated extracorporeally with UVA light after photosensitization using psoralen and then reinfused. This new treatment concept was first published as extracorporeal photopheresis (ECP) in 1987. After initial positive experience with CTCL, this treatment was successfully applied to other indications, including acute and chronic graft-versus-host disease (GvHD), scleroderma, and atopic dermatitis (AD). ECP has been increasingly used in recent years for the treatment of acute and chronic rejection after organ transplantation, especially heart and lung transplantation. As of 2021, there are over 200 centers worldwide that successfully use ECP. More... »

PAGES

207-212

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12326-021-00467-1

DOI

http://dx.doi.org/10.1007/s12326-021-00467-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1141645057


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