Ontology type: schema:ScholarlyArticle Open Access: True
2021-10-05
AUTHORSR. Knobler, T. Valero, U. Just
ABSTRACTMore than 30 years ago, ECP (extracorporeal photochemotherapy) was developed for the treatment of refractory cutaneous T‑cell lymphomas (CTCL), in particular Sézary syndrome. R. Edelson combined leukapheresis with photochemotherapy, where cells of the peripheral blood are irradiated extracorporeally with UVA light after photosensitization using psoralen and then reinfused. This new treatment concept was first published as extracorporeal photopheresis (ECP) in 1987. After initial positive experience with CTCL, this treatment was successfully applied to other indications, including acute and chronic graft-versus-host disease (GvHD), scleroderma, and atopic dermatitis (AD). ECP has been increasingly used in recent years for the treatment of acute and chronic rejection after organ transplantation, especially heart and lung transplantation. As of 2021, there are over 200 centers worldwide that successfully use ECP. More... »
PAGES207-212
http://scigraph.springernature.com/pub.10.1007/s12326-021-00467-1
DOIhttp://dx.doi.org/10.1007/s12326-021-00467-1
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