Clinician Concepts of Cure in Adult Relapsed and Refractory Philadelphia-Negative B Cell Precursor Acute Lymphoblastic Leukemia: A Delphi Study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04

AUTHORS

Renato Bassan, Dieter Hoelzer, Xavier Thomas, Pau Montesinos, Jiri Pavlu, Jan McKendrick, Amber Kudlac, Arie Barlev, Beth Barber, Ze Cong

ABSTRACT

INTRODUCTION: Despite the poor prognosis for adults with relapsed or refractory (RR) Philadelphia chromosome (Ph)-negative B cell precursor acute lymphoblastic leukemia (ALL), long-term survival is possible and may even be considered as "cure". METHODS: This study used a Delphi panel approach to explore concepts of cure in RR Ph-negative B cell precursor ALL. Ten European experts in this disease area participated in a survey and face-to-face panel meeting. RESULTS: Findings showed that clinicians conceptualize "cure" as a combination of three broad treatment outcomes that vary depending on the treatment stage: complete remission early in treatment (1-3 months) indicates initial success; eradicating cancer cells (minimal residual disease negative status) consolidates the early clinical response; leukemia-free survival is required in the long term. CONCLUSIONS: Although such terminology remains contested, clinicians would begin considering "cure" as early as 2 years provided the patient is off therapy, with most considering the term applicable by the third year. FUNDING: Amgen Inc. More... »

PAGES

870-879

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12325-019-00910-z

DOI

http://dx.doi.org/10.1007/s12325-019-00910-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112607175

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30847777


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "UOC Ematologia, Ospedale dell\u2019Angelo e Ospedale SS Giovanni e Paolo, Mestre, Venice, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bassan", 
        "givenName": "Renato", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.411088.4", 
          "name": [
            "University Hospital, Frankfurt, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hoelzer", 
        "givenName": "Dieter", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Lyon-Sud Hospital, Pierre-B\u00e9nite, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Thomas", 
        "givenName": "Xavier", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitari i Polit\u00e8cnic La Fe", 
          "id": "https://www.grid.ac/institutes/grid.84393.35", 
          "name": [
            "Hospital Universitari i Polit\u00e8cnic La Fe, Valencia, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Montesinos", 
        "givenName": "Pau", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Imperial College London", 
          "id": "https://www.grid.ac/institutes/grid.7445.2", 
          "name": [
            "Centre for Haematology, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pavlu", 
        "givenName": "Jiri", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Technology Sydney", 
          "id": "https://www.grid.ac/institutes/grid.117476.2", 
          "name": [
            "PRMA Consulting Ltd, Fleet, UK", 
            "Faculty of Health, University of Technology Sydney, Sydney, NSW, Australia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "McKendrick", 
        "givenName": "Jan", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "PRMA Consulting Ltd, Fleet, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kudlac", 
        "givenName": "Amber", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Amgen (United States)", 
          "id": "https://www.grid.ac/institutes/grid.417886.4", 
          "name": [
            "Amgen Inc., Thousand Oaks, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Barlev", 
        "givenName": "Arie", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Amgen (United States)", 
          "id": "https://www.grid.ac/institutes/grid.417886.4", 
          "name": [
            "Amgen Inc., Thousand Oaks, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Barber", 
        "givenName": "Beth", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Amgen (United States)", 
          "id": "https://www.grid.ac/institutes/grid.417886.4", 
          "name": [
            "Amgen Inc., Thousand Oaks, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cong", 
        "givenName": "Ze", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1200/jco.2008.18.6916", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002988078"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2015/865101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007250733"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.25354", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010549509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.25354", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010549509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2014-09-599894", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011069074"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11899-015-0252-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014027871", 
          "https://doi.org/10.1007/s11899-015-0252-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0889-8588(05)70188-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015538785"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0889-8588(05)70188-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015538785"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1576/toag.7.2.120.27071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016117793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2010.30.1382", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017850303"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2011-12-399287", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018021626"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2012-08-234492", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018590045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbmt.2013.04.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018721654"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3324/haematol.2015.127837", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019442531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2404824", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024302560", 
          "https://doi.org/10.1038/sj.leu.2404824"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11912-011-0185-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024357244", 
          "https://doi.org/10.1007/s11912-011-0185-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1097-0142(19991001)86:7<1216::aid-cncr17>3.0.co;2-o", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025855964"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2015-03-580027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027853442"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.24862", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033461178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.24862", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033461178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdw025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038138749"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3324/haematol.2009.014274", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049198117"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(15)00186-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049259748"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-014-0938-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052358438", 
          "https://doi.org/10.1007/s12032-014-0938-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/1024533031000153621", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058357843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2003.04.036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064203515"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-04", 
    "datePublishedReg": "2019-04-01", 
    "description": "INTRODUCTION: Despite the poor prognosis for adults with relapsed or refractory (RR) Philadelphia chromosome (Ph)-negative B\u00a0cell precursor acute lymphoblastic leukemia (ALL), long-term survival is possible and may even be considered as \"cure\".\nMETHODS: This study used a Delphi panel approach to explore concepts of cure in RR Ph-negative B\u00a0cell precursor ALL. Ten European experts in this disease area participated in a survey and face-to-face panel meeting.\nRESULTS: Findings showed that clinicians conceptualize \"cure\" as a combination of three broad treatment outcomes that vary depending on the treatment stage: complete remission early in treatment (1-3\u00a0months) indicates initial success; eradicating cancer cells (minimal residual disease negative status) consolidates the early clinical response; leukemia-free survival is required in the long term.\nCONCLUSIONS: Although such terminology remains contested, clinicians would begin considering \"cure\" as early as 2\u00a0years provided the patient is off therapy, with most considering the term applicable by the third year.\nFUNDING: Amgen Inc.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s12325-019-00910-z", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1096634", 
        "issn": [
          "0741-238X", 
          "1865-8652"
        ], 
        "name": "Advances in Therapy", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "36"
      }
    ], 
    "name": "Clinician Concepts of Cure in Adult Relapsed and Refractory Philadelphia-Negative B Cell Precursor Acute Lymphoblastic Leukemia: A Delphi Study", 
    "pagination": "870-879", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "3c98a383e8bfd9d49f11bf60d4dd46d1b11a96b634119e4fdacc71cf1bfbe26b"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30847777"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "8611864"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12325-019-00910-z"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112607175"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12325-019-00910-z", 
      "https://app.dimensions.ai/details/publication/pub.1112607175"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:58", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000365_0000000365/records_71689_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs12325-019-00910-z"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12325-019-00910-z'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12325-019-00910-z'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12325-019-00910-z'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12325-019-00910-z'


 

This table displays all metadata directly associated to this object as RDF triples.

214 TRIPLES      21 PREDICATES      52 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12325-019-00910-z schema:about anzsrc-for:11
2 anzsrc-for:1112
3 schema:author N295b72ce9dd848b0a35f3ded68247437
4 schema:citation sg:pub.10.1007/s11899-015-0252-7
5 sg:pub.10.1007/s11912-011-0185-9
6 sg:pub.10.1007/s12032-014-0938-z
7 sg:pub.10.1038/sj.leu.2404824
8 https://doi.org/10.1002/(sici)1097-0142(19991001)86:7<1216::aid-cncr17>3.0.co;2-o
9 https://doi.org/10.1002/cncr.24862
10 https://doi.org/10.1002/cncr.25354
11 https://doi.org/10.1016/j.bbmt.2013.04.014
12 https://doi.org/10.1016/s0889-8588(05)70188-x
13 https://doi.org/10.1016/s1470-2045(15)00186-2
14 https://doi.org/10.1080/1024533031000153621
15 https://doi.org/10.1093/annonc/mdw025
16 https://doi.org/10.1155/2015/865101
17 https://doi.org/10.1182/blood-2011-12-399287
18 https://doi.org/10.1182/blood-2012-08-234492
19 https://doi.org/10.1182/blood-2014-09-599894
20 https://doi.org/10.1182/blood-2015-03-580027
21 https://doi.org/10.1200/jco.2003.04.036
22 https://doi.org/10.1200/jco.2008.18.6916
23 https://doi.org/10.1200/jco.2010.30.1382
24 https://doi.org/10.1576/toag.7.2.120.27071
25 https://doi.org/10.3324/haematol.2009.014274
26 https://doi.org/10.3324/haematol.2015.127837
27 schema:datePublished 2019-04
28 schema:datePublishedReg 2019-04-01
29 schema:description INTRODUCTION: Despite the poor prognosis for adults with relapsed or refractory (RR) Philadelphia chromosome (Ph)-negative B cell precursor acute lymphoblastic leukemia (ALL), long-term survival is possible and may even be considered as "cure". METHODS: This study used a Delphi panel approach to explore concepts of cure in RR Ph-negative B cell precursor ALL. Ten European experts in this disease area participated in a survey and face-to-face panel meeting. RESULTS: Findings showed that clinicians conceptualize "cure" as a combination of three broad treatment outcomes that vary depending on the treatment stage: complete remission early in treatment (1-3 months) indicates initial success; eradicating cancer cells (minimal residual disease negative status) consolidates the early clinical response; leukemia-free survival is required in the long term. CONCLUSIONS: Although such terminology remains contested, clinicians would begin considering "cure" as early as 2 years provided the patient is off therapy, with most considering the term applicable by the third year. FUNDING: Amgen Inc.
30 schema:genre research_article
31 schema:inLanguage en
32 schema:isAccessibleForFree false
33 schema:isPartOf N1e9d501510414e5582573de3162ab7d8
34 N7d36168c08c04b8d8dfe2e87d6e42779
35 sg:journal.1096634
36 schema:name Clinician Concepts of Cure in Adult Relapsed and Refractory Philadelphia-Negative B Cell Precursor Acute Lymphoblastic Leukemia: A Delphi Study
37 schema:pagination 870-879
38 schema:productId N1acbf709a7a8408e89c62e11afeac7eb
39 N1cc2aabc74f04f2abd96ab31ffcab197
40 N2b30fb99e79e4fb2a9e8b4e992d72669
41 Ndee203f2c252425abbc50b3f8341c323
42 Nf5fdaa0eee4a4b77a4f82652890b5427
43 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112607175
44 https://doi.org/10.1007/s12325-019-00910-z
45 schema:sdDatePublished 2019-04-11T12:58
46 schema:sdLicense https://scigraph.springernature.com/explorer/license/
47 schema:sdPublisher Nbc4d1e7c6b264e09af1f5115eae7dcae
48 schema:url https://link.springer.com/10.1007%2Fs12325-019-00910-z
49 sgo:license sg:explorer/license/
50 sgo:sdDataset articles
51 rdf:type schema:ScholarlyArticle
52 N001ba47315b84ddfae62dab23e44c707 schema:name Lyon-Sud Hospital, Pierre-Bénite, France
53 rdf:type schema:Organization
54 N104f80a30ef245d38182b62136694b8f rdf:first N777794569b7d4dbcaa8c58125adae5c6
55 rdf:rest Nf11058533df345e3a9a539cafad454c8
56 N1acbf709a7a8408e89c62e11afeac7eb schema:name pubmed_id
57 schema:value 30847777
58 rdf:type schema:PropertyValue
59 N1cc2aabc74f04f2abd96ab31ffcab197 schema:name dimensions_id
60 schema:value pub.1112607175
61 rdf:type schema:PropertyValue
62 N1e9d501510414e5582573de3162ab7d8 schema:volumeNumber 36
63 rdf:type schema:PublicationVolume
64 N295b72ce9dd848b0a35f3ded68247437 rdf:first Nbd54c7880fb04a4abef9481974126a42
65 rdf:rest Nd5b6ceeb6293402a8d77afe4b1ca4ee8
66 N2b30fb99e79e4fb2a9e8b4e992d72669 schema:name readcube_id
67 schema:value 3c98a383e8bfd9d49f11bf60d4dd46d1b11a96b634119e4fdacc71cf1bfbe26b
68 rdf:type schema:PropertyValue
69 N3db3e8c0420e4b05a620faba05070d99 rdf:first N618a602f28d64903a59b843f93d4d0fa
70 rdf:rest N6872bb3324d04acc966d7ad8cd27f332
71 N4349e9b1c7164b0094c3a248dd719253 schema:affiliation https://www.grid.ac/institutes/grid.411088.4
72 schema:familyName Hoelzer
73 schema:givenName Dieter
74 rdf:type schema:Person
75 N5c9c95c8ac32433495d772de45a33f19 schema:affiliation https://www.grid.ac/institutes/grid.417886.4
76 schema:familyName Barber
77 schema:givenName Beth
78 rdf:type schema:Person
79 N618a602f28d64903a59b843f93d4d0fa schema:affiliation https://www.grid.ac/institutes/grid.84393.35
80 schema:familyName Montesinos
81 schema:givenName Pau
82 rdf:type schema:Person
83 N6872bb3324d04acc966d7ad8cd27f332 rdf:first Nc0e3993246a247afbb7a67a910e054da
84 rdf:rest Ne32728f339c345b2bebd8c7ddcdafc5e
85 N777794569b7d4dbcaa8c58125adae5c6 schema:affiliation https://www.grid.ac/institutes/grid.417886.4
86 schema:familyName Barlev
87 schema:givenName Arie
88 rdf:type schema:Person
89 N7ce6dda04ecf41bf8f96fc94cb3cf697 schema:affiliation N001ba47315b84ddfae62dab23e44c707
90 schema:familyName Thomas
91 schema:givenName Xavier
92 rdf:type schema:Person
93 N7d36168c08c04b8d8dfe2e87d6e42779 schema:issueNumber 4
94 rdf:type schema:PublicationIssue
95 N8f913290a1c043a484f522c8bca45f81 schema:name UOC Ematologia, Ospedale dell’Angelo e Ospedale SS Giovanni e Paolo, Mestre, Venice, Italy
96 rdf:type schema:Organization
97 N915d5f6f1cfa4a159c95884f5b815d72 schema:affiliation https://www.grid.ac/institutes/grid.117476.2
98 schema:familyName McKendrick
99 schema:givenName Jan
100 rdf:type schema:Person
101 Nb2f1ac6cd27343bab589f453cb64adb6 rdf:first Nc64258dc9a844006b0afee00b746f838
102 rdf:rest rdf:nil
103 Nbc4d1e7c6b264e09af1f5115eae7dcae schema:name Springer Nature - SN SciGraph project
104 rdf:type schema:Organization
105 Nbd54c7880fb04a4abef9481974126a42 schema:affiliation N8f913290a1c043a484f522c8bca45f81
106 schema:familyName Bassan
107 schema:givenName Renato
108 rdf:type schema:Person
109 Nc0e3993246a247afbb7a67a910e054da schema:affiliation https://www.grid.ac/institutes/grid.7445.2
110 schema:familyName Pavlu
111 schema:givenName Jiri
112 rdf:type schema:Person
113 Nc64258dc9a844006b0afee00b746f838 schema:affiliation https://www.grid.ac/institutes/grid.417886.4
114 schema:familyName Cong
115 schema:givenName Ze
116 rdf:type schema:Person
117 Ncbb0457b4bbe4598b1b1e064b596973c schema:name PRMA Consulting Ltd, Fleet, UK
118 rdf:type schema:Organization
119 Nd422982ce6ea41d596936f34dc924be8 rdf:first Nd52bc461c2ad46239455f9a213a33ef7
120 rdf:rest N104f80a30ef245d38182b62136694b8f
121 Nd52bc461c2ad46239455f9a213a33ef7 schema:affiliation Ncbb0457b4bbe4598b1b1e064b596973c
122 schema:familyName Kudlac
123 schema:givenName Amber
124 rdf:type schema:Person
125 Nd5b6ceeb6293402a8d77afe4b1ca4ee8 rdf:first N4349e9b1c7164b0094c3a248dd719253
126 rdf:rest Nf5c9690347984cfd9e3e52a100f68f23
127 Ndee203f2c252425abbc50b3f8341c323 schema:name doi
128 schema:value 10.1007/s12325-019-00910-z
129 rdf:type schema:PropertyValue
130 Ne32728f339c345b2bebd8c7ddcdafc5e rdf:first N915d5f6f1cfa4a159c95884f5b815d72
131 rdf:rest Nd422982ce6ea41d596936f34dc924be8
132 Nf11058533df345e3a9a539cafad454c8 rdf:first N5c9c95c8ac32433495d772de45a33f19
133 rdf:rest Nb2f1ac6cd27343bab589f453cb64adb6
134 Nf5c9690347984cfd9e3e52a100f68f23 rdf:first N7ce6dda04ecf41bf8f96fc94cb3cf697
135 rdf:rest N3db3e8c0420e4b05a620faba05070d99
136 Nf5fdaa0eee4a4b77a4f82652890b5427 schema:name nlm_unique_id
137 schema:value 8611864
138 rdf:type schema:PropertyValue
139 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
140 schema:name Medical and Health Sciences
141 rdf:type schema:DefinedTerm
142 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
143 schema:name Oncology and Carcinogenesis
144 rdf:type schema:DefinedTerm
145 sg:journal.1096634 schema:issn 0741-238X
146 1865-8652
147 schema:name Advances in Therapy
148 rdf:type schema:Periodical
149 sg:pub.10.1007/s11899-015-0252-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014027871
150 https://doi.org/10.1007/s11899-015-0252-7
151 rdf:type schema:CreativeWork
152 sg:pub.10.1007/s11912-011-0185-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024357244
153 https://doi.org/10.1007/s11912-011-0185-9
154 rdf:type schema:CreativeWork
155 sg:pub.10.1007/s12032-014-0938-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1052358438
156 https://doi.org/10.1007/s12032-014-0938-z
157 rdf:type schema:CreativeWork
158 sg:pub.10.1038/sj.leu.2404824 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024302560
159 https://doi.org/10.1038/sj.leu.2404824
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1002/(sici)1097-0142(19991001)86:7<1216::aid-cncr17>3.0.co;2-o schema:sameAs https://app.dimensions.ai/details/publication/pub.1025855964
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1002/cncr.24862 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033461178
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1002/cncr.25354 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010549509
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1016/j.bbmt.2013.04.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018721654
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1016/s0889-8588(05)70188-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1015538785
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1016/s1470-2045(15)00186-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049259748
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1080/1024533031000153621 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058357843
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1093/annonc/mdw025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038138749
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1155/2015/865101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007250733
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1182/blood-2011-12-399287 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018021626
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1182/blood-2012-08-234492 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018590045
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1182/blood-2014-09-599894 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011069074
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1182/blood-2015-03-580027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027853442
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1200/jco.2003.04.036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064203515
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1200/jco.2008.18.6916 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002988078
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1200/jco.2010.30.1382 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017850303
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1576/toag.7.2.120.27071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016117793
194 rdf:type schema:CreativeWork
195 https://doi.org/10.3324/haematol.2009.014274 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049198117
196 rdf:type schema:CreativeWork
197 https://doi.org/10.3324/haematol.2015.127837 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019442531
198 rdf:type schema:CreativeWork
199 https://www.grid.ac/institutes/grid.117476.2 schema:alternateName University of Technology Sydney
200 schema:name Faculty of Health, University of Technology Sydney, Sydney, NSW, Australia
201 PRMA Consulting Ltd, Fleet, UK
202 rdf:type schema:Organization
203 https://www.grid.ac/institutes/grid.411088.4 schema:alternateName University Hospital Frankfurt
204 schema:name University Hospital, Frankfurt, Germany
205 rdf:type schema:Organization
206 https://www.grid.ac/institutes/grid.417886.4 schema:alternateName Amgen (United States)
207 schema:name Amgen Inc., Thousand Oaks, CA, USA
208 rdf:type schema:Organization
209 https://www.grid.ac/institutes/grid.7445.2 schema:alternateName Imperial College London
210 schema:name Centre for Haematology, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, UK
211 rdf:type schema:Organization
212 https://www.grid.ac/institutes/grid.84393.35 schema:alternateName Hospital Universitari i Politècnic La Fe
213 schema:name Hospital Universitari i Politècnic La Fe, Valencia, Spain
214 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...