Clinical Characteristics and Management of 50 Patients with Anti-GAD Ataxia: Gluten-Free Diet Has a Major Impact View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2020-10-21

AUTHORS

M. Hadjivassiliou, P. G. Sarrigiannis, P. D. Shanmugarajah, D. S. Sanders, R. A. Grünewald, P. Zis, N. Hoggard

ABSTRACT

The objective of this study is to report the clinical characteristics and treatment of patients with progressive cerebellar ataxia associated with anti-GAD antibodies. We performed a retrospective review of all patients with anti-GAD ataxia managed at the Sheffield Ataxia Centre over the last 25 years. We identified 50 patients (62% females) with anti-GAD ataxia. The prevalence was 2.5% amongst 2000 patients with progressive ataxia of various causes. Mean age at onset was 55 and mean duration 8 years. Gaze-evoked nystagmus was present in 26%, cerebellar dysarthria in 26%, limb ataxia in 44% and gait ataxia in 100%. Nine patients (18%) had severe, 12 (24%) moderate and 29 (58%) mild ataxia. Ninety percent of patients had a history of additional autoimmune diseases. Family history of autoimmune diseases was seen in 52%. Baseline MR spectroscopy of the vermis was abnormal at presentation in 72%. Thirty-five patients (70%) had serological evidence of gluten sensitivity. All 35 went on gluten-free diet (GFD). Eighteen (51%) improved, 13 (37%) stabilised, 3 have started the GFD too recently to draw conclusions and one deteriorated. Mycophenolate was used in 16 patients, 7 (44%) improved, 2 stabilised, 6 have started the medication too recently to draw conclusions and one did not tolerate the drug. There is considerable overlap between anti-GAD ataxia and gluten ataxia. For those patients with both, strict GFD alone can be an effective treatment. Patients with anti-GAD ataxia and no gluten sensitivity respond well to immunosuppression. More... »

PAGES

179-185

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12311-020-01203-w

DOI

http://dx.doi.org/10.1007/s12311-020-01203-w

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1131934494

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/33084997


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Autoantibodies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Autoantigens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Autoimmune Diseases of the Nervous System", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cerebellar Ataxia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diet, Gluten-Free", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glutamate Decarboxylase", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retrospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK", 
          "id": "http://www.grid.ac/institutes/grid.416126.6", 
          "name": [
            "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hadjivassiliou", 
        "givenName": "M.", 
        "id": "sg:person.01354423242.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354423242.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK", 
          "id": "http://www.grid.ac/institutes/grid.416126.6", 
          "name": [
            "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sarrigiannis", 
        "givenName": "P. G.", 
        "id": "sg:person.01132771412.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132771412.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK", 
          "id": "http://www.grid.ac/institutes/grid.416126.6", 
          "name": [
            "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shanmugarajah", 
        "givenName": "P. D.", 
        "id": "sg:person.01273701327.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01273701327.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK", 
          "id": "http://www.grid.ac/institutes/grid.416126.6", 
          "name": [
            "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sanders", 
        "givenName": "D. S.", 
        "id": "sg:person.016071637312.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016071637312.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK", 
          "id": "http://www.grid.ac/institutes/grid.416126.6", 
          "name": [
            "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gr\u00fcnewald", 
        "givenName": "R. A.", 
        "id": "sg:person.01130424341.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130424341.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK", 
          "id": "http://www.grid.ac/institutes/grid.416126.6", 
          "name": [
            "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zis", 
        "givenName": "P.", 
        "id": "sg:person.0735760516.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735760516.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Academic Department of Neuroradiology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Sheffield, UK", 
          "id": "http://www.grid.ac/institutes/grid.416126.6", 
          "name": [
            "Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK", 
            "Academic Department of Neuroradiology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Sheffield, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hoggard", 
        "givenName": "N.", 
        "id": "sg:person.0610025364.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610025364.39"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s12311-020-01132-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1126922911", 
          "https://doi.org/10.1007/s12311-020-01132-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/2053-8871-1-11", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010244213", 
          "https://doi.org/10.1186/2053-8871-1-11"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s40673-019-0100-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1115176813", 
          "https://doi.org/10.1186/s40673-019-0100-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s001250051105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041002379", 
          "https://doi.org/10.1007/s001250051105"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12311-020-01152-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1128395600", 
          "https://doi.org/10.1007/s12311-020-01152-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s40673-015-0034-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024291047", 
          "https://doi.org/10.1186/s40673-015-0034-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/347151a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016714750", 
          "https://doi.org/10.1038/347151a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/298167a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048748907", 
          "https://doi.org/10.1038/298167a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2020-10-21", 
    "datePublishedReg": "2020-10-21", 
    "description": "The objective of this study is to report the clinical characteristics and treatment of patients with progressive cerebellar ataxia associated with anti-GAD antibodies. We performed a retrospective review of all patients with anti-GAD ataxia managed at the Sheffield Ataxia Centre over the last 25 years. We identified 50 patients (62% females) with anti-GAD ataxia. The prevalence was 2.5% amongst 2000 patients with progressive ataxia of various causes. Mean age at onset was 55 and mean duration 8\u00a0years. Gaze-evoked nystagmus was present in 26%, cerebellar dysarthria in 26%, limb ataxia in 44% and gait ataxia in 100%. Nine patients (18%) had severe, 12 (24%) moderate and 29 (58%) mild ataxia. Ninety percent of patients had a history of additional autoimmune diseases. Family history of autoimmune diseases was seen in 52%. Baseline MR spectroscopy of the vermis was abnormal at presentation in 72%. Thirty-five patients (70%) had serological evidence of gluten sensitivity. All 35 went on gluten-free diet (GFD). Eighteen (51%) improved, 13 (37%) stabilised, 3 have started the GFD too recently to draw conclusions and one deteriorated. Mycophenolate was used in 16 patients, 7 (44%) improved, 2 stabilised, 6 have started the medication too recently to draw conclusions and one did not tolerate the drug. There is considerable overlap between anti-GAD ataxia and gluten ataxia. For those patients with both, strict GFD alone can be an effective treatment. Patients with anti-GAD ataxia and no gluten sensitivity respond well to immunosuppression.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s12311-020-01203-w", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1028483", 
        "issn": [
          "1473-4222", 
          "1473-4230"
        ], 
        "name": "The Cerebellum", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "20"
      }
    ], 
    "keywords": [
      "gluten-free diet", 
      "GAD ataxia", 
      "clinical characteristics", 
      "autoimmune diseases", 
      "gluten sensitivity", 
      "strict gluten-free diet", 
      "anti-GAD antibodies", 
      "Sheffield Ataxia Centre", 
      "additional autoimmune diseases", 
      "percent of patients", 
      "treatment of patients", 
      "progressive cerebellar ataxia", 
      "retrospective review", 
      "serological evidence", 
      "family history", 
      "effective treatment", 
      "patients", 
      "cerebellar dysarthria", 
      "progressive ataxia", 
      "mild ataxia", 
      "cerebellar ataxia", 
      "ataxia", 
      "MR spectroscopy", 
      "duration 8", 
      "disease", 
      "considerable overlap", 
      "diet", 
      "treatment", 
      "conclusion", 
      "mycophenolate", 
      "immunosuppression", 
      "medications", 
      "nystagmus", 
      "years", 
      "dysarthria", 
      "prevalence", 
      "vermis", 
      "antibodies", 
      "drugs", 
      "age", 
      "major impact", 
      "history", 
      "onset", 
      "presentation", 
      "cause", 
      "sensitivity", 
      "percent", 
      "review", 
      "evidence", 
      "management", 
      "center", 
      "study", 
      "objective", 
      "characteristics", 
      "gaze", 
      "impact", 
      "overlap", 
      "spectroscopy"
    ], 
    "name": "Clinical Characteristics and Management of 50 Patients with Anti-GAD Ataxia: Gluten-Free Diet Has a Major Impact", 
    "pagination": "179-185", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1131934494"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12311-020-01203-w"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "33084997"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12311-020-01203-w", 
      "https://app.dimensions.ai/details/publication/pub.1131934494"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-11-24T21:05", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221124/entities/gbq_results/article/article_857.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s12311-020-01203-w"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12311-020-01203-w'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12311-020-01203-w'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12311-020-01203-w'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12311-020-01203-w'


 

This table displays all metadata directly associated to this object as RDF triples.

259 TRIPLES      21 PREDICATES      107 URIs      91 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12311-020-01203-w schema:about N0a4bf07c094d44478ffeb90b9484d422
2 N0f3a9c1b000e4ed0af919ab5d760a384
3 N1ab71c76c4d0492c9e55e457572a1048
4 N2a2987762cf44067ad8e1a5f5b698ce7
5 N2cd12f05c28a499d9698f0cdaf7a2e72
6 N2ed576675e4949be8cc6d288110c55f4
7 N6273d97f709049d7ba8933da1e584d17
8 N67d3210f023f4f94b8bad4fc9271bf82
9 N6a2cc36a04ff489da539b813768b79aa
10 N9896d1ea5cd04921aec3a8a8e61ff0f4
11 Nce832cd2a7c142939ba43540a2a07a81
12 Ncf93bd138d1a424c8cf708a5a5746c77
13 Nd4966691ebf54b50999e6a334f5df378
14 Nd51056aa53bd4ce1a2d5e6e4e4e922b0
15 Neaafc440b5844f3f97f926b551c43a66
16 Nf900b19b68e944a4b94092f271fe37bd
17 anzsrc-for:11
18 anzsrc-for:1107
19 schema:author Nb82af089a0164cd5a9f05f262332f21f
20 schema:citation sg:pub.10.1007/s001250051105
21 sg:pub.10.1007/s12311-020-01132-8
22 sg:pub.10.1007/s12311-020-01152-4
23 sg:pub.10.1038/298167a0
24 sg:pub.10.1038/347151a0
25 sg:pub.10.1186/2053-8871-1-11
26 sg:pub.10.1186/s40673-015-0034-y
27 sg:pub.10.1186/s40673-019-0100-y
28 schema:datePublished 2020-10-21
29 schema:datePublishedReg 2020-10-21
30 schema:description The objective of this study is to report the clinical characteristics and treatment of patients with progressive cerebellar ataxia associated with anti-GAD antibodies. We performed a retrospective review of all patients with anti-GAD ataxia managed at the Sheffield Ataxia Centre over the last 25 years. We identified 50 patients (62% females) with anti-GAD ataxia. The prevalence was 2.5% amongst 2000 patients with progressive ataxia of various causes. Mean age at onset was 55 and mean duration 8 years. Gaze-evoked nystagmus was present in 26%, cerebellar dysarthria in 26%, limb ataxia in 44% and gait ataxia in 100%. Nine patients (18%) had severe, 12 (24%) moderate and 29 (58%) mild ataxia. Ninety percent of patients had a history of additional autoimmune diseases. Family history of autoimmune diseases was seen in 52%. Baseline MR spectroscopy of the vermis was abnormal at presentation in 72%. Thirty-five patients (70%) had serological evidence of gluten sensitivity. All 35 went on gluten-free diet (GFD). Eighteen (51%) improved, 13 (37%) stabilised, 3 have started the GFD too recently to draw conclusions and one deteriorated. Mycophenolate was used in 16 patients, 7 (44%) improved, 2 stabilised, 6 have started the medication too recently to draw conclusions and one did not tolerate the drug. There is considerable overlap between anti-GAD ataxia and gluten ataxia. For those patients with both, strict GFD alone can be an effective treatment. Patients with anti-GAD ataxia and no gluten sensitivity respond well to immunosuppression.
31 schema:genre article
32 schema:isAccessibleForFree true
33 schema:isPartOf N397281d77f6947ffb19e9ad788fd7445
34 N6280f59aa20445b986a4dfa49940408b
35 sg:journal.1028483
36 schema:keywords GAD ataxia
37 MR spectroscopy
38 Sheffield Ataxia Centre
39 additional autoimmune diseases
40 age
41 anti-GAD antibodies
42 antibodies
43 ataxia
44 autoimmune diseases
45 cause
46 center
47 cerebellar ataxia
48 cerebellar dysarthria
49 characteristics
50 clinical characteristics
51 conclusion
52 considerable overlap
53 diet
54 disease
55 drugs
56 duration 8
57 dysarthria
58 effective treatment
59 evidence
60 family history
61 gaze
62 gluten sensitivity
63 gluten-free diet
64 history
65 immunosuppression
66 impact
67 major impact
68 management
69 medications
70 mild ataxia
71 mycophenolate
72 nystagmus
73 objective
74 onset
75 overlap
76 patients
77 percent
78 percent of patients
79 presentation
80 prevalence
81 progressive ataxia
82 progressive cerebellar ataxia
83 retrospective review
84 review
85 sensitivity
86 serological evidence
87 spectroscopy
88 strict gluten-free diet
89 study
90 treatment
91 treatment of patients
92 vermis
93 years
94 schema:name Clinical Characteristics and Management of 50 Patients with Anti-GAD Ataxia: Gluten-Free Diet Has a Major Impact
95 schema:pagination 179-185
96 schema:productId N099c8b48fb7e47c7afc163124257655e
97 N6e226fcc1a22462fbc1fbdceded1f67b
98 N7d7bfc091e194927a65b3e44625e4d35
99 schema:sameAs https://app.dimensions.ai/details/publication/pub.1131934494
100 https://doi.org/10.1007/s12311-020-01203-w
101 schema:sdDatePublished 2022-11-24T21:05
102 schema:sdLicense https://scigraph.springernature.com/explorer/license/
103 schema:sdPublisher Nddf121556d8c46d1ac9344b83f913e0d
104 schema:url https://doi.org/10.1007/s12311-020-01203-w
105 sgo:license sg:explorer/license/
106 sgo:sdDataset articles
107 rdf:type schema:ScholarlyArticle
108 N099c8b48fb7e47c7afc163124257655e schema:name dimensions_id
109 schema:value pub.1131934494
110 rdf:type schema:PropertyValue
111 N0a4bf07c094d44478ffeb90b9484d422 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Autoantigens
113 rdf:type schema:DefinedTerm
114 N0f3a9c1b000e4ed0af919ab5d760a384 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Female
116 rdf:type schema:DefinedTerm
117 N1ab71c76c4d0492c9e55e457572a1048 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Autoimmune Diseases of the Nervous System
119 rdf:type schema:DefinedTerm
120 N2a2987762cf44067ad8e1a5f5b698ce7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Aged, 80 and over
122 rdf:type schema:DefinedTerm
123 N2cd12f05c28a499d9698f0cdaf7a2e72 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Glutamate Decarboxylase
125 rdf:type schema:DefinedTerm
126 N2ed576675e4949be8cc6d288110c55f4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Cerebellar Ataxia
128 rdf:type schema:DefinedTerm
129 N397281d77f6947ffb19e9ad788fd7445 schema:issueNumber 2
130 rdf:type schema:PublicationIssue
131 N6273d97f709049d7ba8933da1e584d17 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Male
133 rdf:type schema:DefinedTerm
134 N6280f59aa20445b986a4dfa49940408b schema:volumeNumber 20
135 rdf:type schema:PublicationVolume
136 N67d3210f023f4f94b8bad4fc9271bf82 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Retrospective Studies
138 rdf:type schema:DefinedTerm
139 N6a2cc36a04ff489da539b813768b79aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Middle Aged
141 rdf:type schema:DefinedTerm
142 N6e226fcc1a22462fbc1fbdceded1f67b schema:name pubmed_id
143 schema:value 33084997
144 rdf:type schema:PropertyValue
145 N7d7bfc091e194927a65b3e44625e4d35 schema:name doi
146 schema:value 10.1007/s12311-020-01203-w
147 rdf:type schema:PropertyValue
148 N84e7efe17bde49dd969d5ec2f716b3cf rdf:first sg:person.01130424341.44
149 rdf:rest N9316bc5d62224a90a7647c3115ba7803
150 N9316bc5d62224a90a7647c3115ba7803 rdf:first sg:person.0735760516.32
151 rdf:rest Nb757bee1a64c410f9fec4003465bdfc8
152 N9896d1ea5cd04921aec3a8a8e61ff0f4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Autoantibodies
154 rdf:type schema:DefinedTerm
155 Nb757bee1a64c410f9fec4003465bdfc8 rdf:first sg:person.0610025364.39
156 rdf:rest rdf:nil
157 Nb82af089a0164cd5a9f05f262332f21f rdf:first sg:person.01354423242.83
158 rdf:rest Nd541712b4bed48a38085f87c7d043f65
159 Nbcd8419686404e2e9efced5599028bab rdf:first sg:person.01273701327.13
160 rdf:rest Nf231139bb0734f00a63f52d92e5d9116
161 Nce832cd2a7c142939ba43540a2a07a81 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Diet, Gluten-Free
163 rdf:type schema:DefinedTerm
164 Ncf93bd138d1a424c8cf708a5a5746c77 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Young Adult
166 rdf:type schema:DefinedTerm
167 Nd4966691ebf54b50999e6a334f5df378 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Adult
169 rdf:type schema:DefinedTerm
170 Nd51056aa53bd4ce1a2d5e6e4e4e922b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Humans
172 rdf:type schema:DefinedTerm
173 Nd541712b4bed48a38085f87c7d043f65 rdf:first sg:person.01132771412.11
174 rdf:rest Nbcd8419686404e2e9efced5599028bab
175 Nddf121556d8c46d1ac9344b83f913e0d schema:name Springer Nature - SN SciGraph project
176 rdf:type schema:Organization
177 Neaafc440b5844f3f97f926b551c43a66 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Adolescent
179 rdf:type schema:DefinedTerm
180 Nf231139bb0734f00a63f52d92e5d9116 rdf:first sg:person.016071637312.37
181 rdf:rest N84e7efe17bde49dd969d5ec2f716b3cf
182 Nf900b19b68e944a4b94092f271fe37bd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Aged
184 rdf:type schema:DefinedTerm
185 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
186 schema:name Medical and Health Sciences
187 rdf:type schema:DefinedTerm
188 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
189 schema:name Immunology
190 rdf:type schema:DefinedTerm
191 sg:journal.1028483 schema:issn 1473-4222
192 1473-4230
193 schema:name The Cerebellum
194 schema:publisher Springer Nature
195 rdf:type schema:Periodical
196 sg:person.01130424341.44 schema:affiliation grid-institutes:grid.416126.6
197 schema:familyName Grünewald
198 schema:givenName R. A.
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130424341.44
200 rdf:type schema:Person
201 sg:person.01132771412.11 schema:affiliation grid-institutes:grid.416126.6
202 schema:familyName Sarrigiannis
203 schema:givenName P. G.
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132771412.11
205 rdf:type schema:Person
206 sg:person.01273701327.13 schema:affiliation grid-institutes:grid.416126.6
207 schema:familyName Shanmugarajah
208 schema:givenName P. D.
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01273701327.13
210 rdf:type schema:Person
211 sg:person.01354423242.83 schema:affiliation grid-institutes:grid.416126.6
212 schema:familyName Hadjivassiliou
213 schema:givenName M.
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354423242.83
215 rdf:type schema:Person
216 sg:person.016071637312.37 schema:affiliation grid-institutes:grid.416126.6
217 schema:familyName Sanders
218 schema:givenName D. S.
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016071637312.37
220 rdf:type schema:Person
221 sg:person.0610025364.39 schema:affiliation grid-institutes:grid.416126.6
222 schema:familyName Hoggard
223 schema:givenName N.
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610025364.39
225 rdf:type schema:Person
226 sg:person.0735760516.32 schema:affiliation grid-institutes:grid.416126.6
227 schema:familyName Zis
228 schema:givenName P.
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735760516.32
230 rdf:type schema:Person
231 sg:pub.10.1007/s001250051105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041002379
232 https://doi.org/10.1007/s001250051105
233 rdf:type schema:CreativeWork
234 sg:pub.10.1007/s12311-020-01132-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1126922911
235 https://doi.org/10.1007/s12311-020-01132-8
236 rdf:type schema:CreativeWork
237 sg:pub.10.1007/s12311-020-01152-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1128395600
238 https://doi.org/10.1007/s12311-020-01152-4
239 rdf:type schema:CreativeWork
240 sg:pub.10.1038/298167a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048748907
241 https://doi.org/10.1038/298167a0
242 rdf:type schema:CreativeWork
243 sg:pub.10.1038/347151a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016714750
244 https://doi.org/10.1038/347151a0
245 rdf:type schema:CreativeWork
246 sg:pub.10.1186/2053-8871-1-11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010244213
247 https://doi.org/10.1186/2053-8871-1-11
248 rdf:type schema:CreativeWork
249 sg:pub.10.1186/s40673-015-0034-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1024291047
250 https://doi.org/10.1186/s40673-015-0034-y
251 rdf:type schema:CreativeWork
252 sg:pub.10.1186/s40673-019-0100-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1115176813
253 https://doi.org/10.1186/s40673-019-0100-y
254 rdf:type schema:CreativeWork
255 grid-institutes:grid.416126.6 schema:alternateName Academic Department of Neuroradiology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Sheffield, UK
256 Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK
257 schema:name Academic Department of Neuroradiology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Sheffield, UK
258 Academic Department of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Glossop Road, S10 2JF, Sheffield, UK
259 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...