The use of fluoride cement: preliminary experimental study and clinical application View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-04

AUTHORS

Claudia Di Bella, Enrico Lucarelli, Milena Fini, Roberto Giardino, Mario Mercuri, Davide Donati

ABSTRACT

One of the most common complications of cemented prostheses is aseptic loosening of the implant, which is often due to mechanical breakdown at the bone-cement interface. To improve the characteristics of PMMA, the addition of fluoride has been proposed, which, without jeopardising its mechanical qualities, should provide better integration with the surrounding bone. An experimental study was performed in 4 sheep. A cylinder of cement (with and without fluoride) was inserted in the meta-epiphysis of the distal femur. A clinical study followed 7 patients. The cement with added fluoride was used as a filler after the curettage of a benign tumour located in the meta-epiphysis around the knee. Histological results in animals combined with long-term radiographic results in humans have shown the positive influence of fluoride in the cement, as it allows better integration of the cement with the surrounding bone. More... »

PAGES

141-146

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12306-007-0023-2

DOI

http://dx.doi.org/10.1007/s12306-007-0023-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031238355

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18493832


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Cements", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fluorides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Osseointegration", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sheep", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Bone Tissue Regeneration Laboratory, Istituto Ortopedico Rizzoli, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.419038.7", 
          "name": [
            "V Orthopedic Ward, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136, Bologna, Italy", 
            "Bone Tissue Regeneration Laboratory, Istituto Ortopedico Rizzoli, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Di Bella", 
        "givenName": "Claudia", 
        "id": "sg:person.01162632200.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162632200.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Bone Tissue Regeneration Laboratory, Istituto Ortopedico Rizzoli, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.419038.7", 
          "name": [
            "Bone Tissue Regeneration Laboratory, Istituto Ortopedico Rizzoli, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lucarelli", 
        "givenName": "Enrico", 
        "id": "sg:person.0670605411.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670605411.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Experimental Surgery, Istituto Ortopedico Rizzoli, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.419038.7", 
          "name": [
            "Experimental Surgery, Istituto Ortopedico Rizzoli, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fini", 
        "givenName": "Milena", 
        "id": "sg:person.0776126134.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776126134.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Experimental Surgery, Istituto Ortopedico Rizzoli, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.419038.7", 
          "name": [
            "Experimental Surgery, Istituto Ortopedico Rizzoli, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Giardino", 
        "givenName": "Roberto", 
        "id": "sg:person.01155465220.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155465220.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "V Orthopedic Ward, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.419038.7", 
          "name": [
            "V Orthopedic Ward, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mercuri", 
        "givenName": "Mario", 
        "id": "sg:person.01062073475.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062073475.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Bone Tissue Regeneration Laboratory, Istituto Ortopedico Rizzoli, Bologna, Italy", 
          "id": "http://www.grid.ac/institutes/grid.419038.7", 
          "name": [
            "V Orthopedic Ward, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136, Bologna, Italy", 
            "Bone Tissue Regeneration Laboratory, Istituto Ortopedico Rizzoli, Bologna, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Donati", 
        "givenName": "Davide", 
        "id": "sg:person.01202643430.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202643430.41"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/191184a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005701638", 
          "https://doi.org/10.1038/191184a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-04", 
    "datePublishedReg": "2008-04-01", 
    "description": "One of the most common complications of cemented prostheses is aseptic loosening of the implant, which is often due to mechanical breakdown at the bone-cement interface. To improve the characteristics of PMMA, the addition of fluoride has been proposed, which, without jeopardising its mechanical qualities, should provide better integration with the surrounding bone. An experimental study was performed in 4 sheep. A cylinder of cement (with and without fluoride) was inserted in the meta-epiphysis of the distal femur. A clinical study followed 7 patients. The cement with added fluoride was used as a filler after the curettage of a benign tumour located in the meta-epiphysis around the knee. Histological results in animals combined with long-term radiographic results in humans have shown the positive influence of fluoride in the cement, as it allows better integration of the cement with the surrounding bone.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s12306-007-0023-2", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1017325", 
        "issn": [
          "2035-5106", 
          "2035-5114"
        ], 
        "name": "MUSCULOSKELETAL SURGERY", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "91"
      }
    ], 
    "keywords": [
      "long-term radiographic results", 
      "common complication", 
      "radiographic results", 
      "clinical studies", 
      "benign tumors", 
      "bone-cement interface", 
      "distal femur", 
      "aseptic loosening", 
      "histological results", 
      "fluoride cement", 
      "clinical application", 
      "bone", 
      "curettage", 
      "complications", 
      "patients", 
      "tumors", 
      "knee", 
      "femur", 
      "study", 
      "prosthesis", 
      "loosening", 
      "implants", 
      "animals", 
      "better integration", 
      "addition of fluoride", 
      "characteristics of PMMA", 
      "humans", 
      "sheep", 
      "experimental study", 
      "preliminary experimental study", 
      "fluoride", 
      "results", 
      "use", 
      "positive influence", 
      "addition", 
      "quality", 
      "breakdown", 
      "cement", 
      "characteristics", 
      "mechanical quality", 
      "influence", 
      "mechanical breakdown", 
      "integration", 
      "applications", 
      "filler", 
      "cylinder", 
      "PMMA", 
      "interface"
    ], 
    "name": "The use of fluoride cement: preliminary experimental study and clinical application", 
    "pagination": "141-146", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1031238355"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12306-007-0023-2"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18493832"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12306-007-0023-2", 
      "https://app.dimensions.ai/details/publication/pub.1031238355"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T15:52", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_468.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s12306-007-0023-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12306-007-0023-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12306-007-0023-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12306-007-0023-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12306-007-0023-2'


 

This table displays all metadata directly associated to this object as RDF triples.

196 TRIPLES      21 PREDICATES      86 URIs      77 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12306-007-0023-2 schema:about N0509b34fea794a70a22b78011bde03ce
2 N114cfd84d10f4e0f9cd7bf5af38542b1
3 N35ef22c06ff7408684453e91b08904a3
4 N806f11a816e148ab93c3688a8fe9c22a
5 N80af59829bad43f29a8bcdf144345899
6 N8d60a69abe984587818ff35f5221440b
7 Nb0f9ae5dc30b4bbd9787364a6d2789aa
8 Ncc02b76a6ed147dabe9701c722df9067
9 Nd07fbbd93b454b6b89f3c83cf61bbb9a
10 Ndadd728054bb44fb96d341d733567f77
11 Nf2b89c5ef0614832a625d417b0766156
12 anzsrc-for:11
13 anzsrc-for:1103
14 schema:author Ne37342c450044c639ee0d132f6d7f312
15 schema:citation sg:pub.10.1038/191184a0
16 schema:datePublished 2008-04
17 schema:datePublishedReg 2008-04-01
18 schema:description One of the most common complications of cemented prostheses is aseptic loosening of the implant, which is often due to mechanical breakdown at the bone-cement interface. To improve the characteristics of PMMA, the addition of fluoride has been proposed, which, without jeopardising its mechanical qualities, should provide better integration with the surrounding bone. An experimental study was performed in 4 sheep. A cylinder of cement (with and without fluoride) was inserted in the meta-epiphysis of the distal femur. A clinical study followed 7 patients. The cement with added fluoride was used as a filler after the curettage of a benign tumour located in the meta-epiphysis around the knee. Histological results in animals combined with long-term radiographic results in humans have shown the positive influence of fluoride in the cement, as it allows better integration of the cement with the surrounding bone.
19 schema:genre article
20 schema:isAccessibleForFree false
21 schema:isPartOf N1d4a341ffb1846c283288cbad6f8deb8
22 Nca5c705785084604ae9d1c8c93c5a1c3
23 sg:journal.1017325
24 schema:keywords PMMA
25 addition
26 addition of fluoride
27 animals
28 applications
29 aseptic loosening
30 benign tumors
31 better integration
32 bone
33 bone-cement interface
34 breakdown
35 cement
36 characteristics
37 characteristics of PMMA
38 clinical application
39 clinical studies
40 common complication
41 complications
42 curettage
43 cylinder
44 distal femur
45 experimental study
46 femur
47 filler
48 fluoride
49 fluoride cement
50 histological results
51 humans
52 implants
53 influence
54 integration
55 interface
56 knee
57 long-term radiographic results
58 loosening
59 mechanical breakdown
60 mechanical quality
61 patients
62 positive influence
63 preliminary experimental study
64 prosthesis
65 quality
66 radiographic results
67 results
68 sheep
69 study
70 tumors
71 use
72 schema:name The use of fluoride cement: preliminary experimental study and clinical application
73 schema:pagination 141-146
74 schema:productId N74dd8e85d9364b84982b3c89427f7921
75 N8249e287c5d54cdb97ab8e310d8b311a
76 Nc165ee294a8f4522a318ce057bb9e1ca
77 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031238355
78 https://doi.org/10.1007/s12306-007-0023-2
79 schema:sdDatePublished 2022-09-02T15:52
80 schema:sdLicense https://scigraph.springernature.com/explorer/license/
81 schema:sdPublisher Nb4932f9539bd4f8ea6a05fd93cf32c2f
82 schema:url https://doi.org/10.1007/s12306-007-0023-2
83 sgo:license sg:explorer/license/
84 sgo:sdDataset articles
85 rdf:type schema:ScholarlyArticle
86 N0509b34fea794a70a22b78011bde03ce schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Adult
88 rdf:type schema:DefinedTerm
89 N114cfd84d10f4e0f9cd7bf5af38542b1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Animals
91 rdf:type schema:DefinedTerm
92 N1d4a341ffb1846c283288cbad6f8deb8 schema:issueNumber 3
93 rdf:type schema:PublicationIssue
94 N35ef22c06ff7408684453e91b08904a3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Bone Cements
96 rdf:type schema:DefinedTerm
97 N69b8ed5759664c8d8a1eaece32ea00ed rdf:first sg:person.01062073475.32
98 rdf:rest N773f96f838d042998cf7e786c6c749ab
99 N74dd8e85d9364b84982b3c89427f7921 schema:name dimensions_id
100 schema:value pub.1031238355
101 rdf:type schema:PropertyValue
102 N773f96f838d042998cf7e786c6c749ab rdf:first sg:person.01202643430.41
103 rdf:rest rdf:nil
104 N806f11a816e148ab93c3688a8fe9c22a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Follow-Up Studies
106 rdf:type schema:DefinedTerm
107 N80af59829bad43f29a8bcdf144345899 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Sheep
109 rdf:type schema:DefinedTerm
110 N8249e287c5d54cdb97ab8e310d8b311a schema:name doi
111 schema:value 10.1007/s12306-007-0023-2
112 rdf:type schema:PropertyValue
113 N8d60a69abe984587818ff35f5221440b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Adolescent
115 rdf:type schema:DefinedTerm
116 Na962a60acd124318a0517ff4342f7612 rdf:first sg:person.01155465220.24
117 rdf:rest N69b8ed5759664c8d8a1eaece32ea00ed
118 Nb0f9ae5dc30b4bbd9787364a6d2789aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Bone Neoplasms
120 rdf:type schema:DefinedTerm
121 Nb25c32dc78ea4ae3a0784994994da587 rdf:first sg:person.0776126134.14
122 rdf:rest Na962a60acd124318a0517ff4342f7612
123 Nb4932f9539bd4f8ea6a05fd93cf32c2f schema:name Springer Nature - SN SciGraph project
124 rdf:type schema:Organization
125 Nc165ee294a8f4522a318ce057bb9e1ca schema:name pubmed_id
126 schema:value 18493832
127 rdf:type schema:PropertyValue
128 Nca5c705785084604ae9d1c8c93c5a1c3 schema:volumeNumber 91
129 rdf:type schema:PublicationVolume
130 Ncc02b76a6ed147dabe9701c722df9067 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Young Adult
132 rdf:type schema:DefinedTerm
133 Nd07fbbd93b454b6b89f3c83cf61bbb9a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Fluorides
135 rdf:type schema:DefinedTerm
136 Ndadd728054bb44fb96d341d733567f77 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Humans
138 rdf:type schema:DefinedTerm
139 Ne2c48df7e41040abafc0a3de82166430 rdf:first sg:person.0670605411.38
140 rdf:rest Nb25c32dc78ea4ae3a0784994994da587
141 Ne37342c450044c639ee0d132f6d7f312 rdf:first sg:person.01162632200.00
142 rdf:rest Ne2c48df7e41040abafc0a3de82166430
143 Nf2b89c5ef0614832a625d417b0766156 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Osseointegration
145 rdf:type schema:DefinedTerm
146 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
147 schema:name Medical and Health Sciences
148 rdf:type schema:DefinedTerm
149 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
150 schema:name Clinical Sciences
151 rdf:type schema:DefinedTerm
152 sg:journal.1017325 schema:issn 2035-5106
153 2035-5114
154 schema:name MUSCULOSKELETAL SURGERY
155 schema:publisher Springer Nature
156 rdf:type schema:Periodical
157 sg:person.01062073475.32 schema:affiliation grid-institutes:grid.419038.7
158 schema:familyName Mercuri
159 schema:givenName Mario
160 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062073475.32
161 rdf:type schema:Person
162 sg:person.01155465220.24 schema:affiliation grid-institutes:grid.419038.7
163 schema:familyName Giardino
164 schema:givenName Roberto
165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155465220.24
166 rdf:type schema:Person
167 sg:person.01162632200.00 schema:affiliation grid-institutes:grid.419038.7
168 schema:familyName Di Bella
169 schema:givenName Claudia
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162632200.00
171 rdf:type schema:Person
172 sg:person.01202643430.41 schema:affiliation grid-institutes:grid.419038.7
173 schema:familyName Donati
174 schema:givenName Davide
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202643430.41
176 rdf:type schema:Person
177 sg:person.0670605411.38 schema:affiliation grid-institutes:grid.419038.7
178 schema:familyName Lucarelli
179 schema:givenName Enrico
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670605411.38
181 rdf:type schema:Person
182 sg:person.0776126134.14 schema:affiliation grid-institutes:grid.419038.7
183 schema:familyName Fini
184 schema:givenName Milena
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0776126134.14
186 rdf:type schema:Person
187 sg:pub.10.1038/191184a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005701638
188 https://doi.org/10.1038/191184a0
189 rdf:type schema:CreativeWork
190 grid-institutes:grid.419038.7 schema:alternateName Bone Tissue Regeneration Laboratory, Istituto Ortopedico Rizzoli, Bologna, Italy
191 Experimental Surgery, Istituto Ortopedico Rizzoli, Bologna, Italy
192 V Orthopedic Ward, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136, Bologna, Italy
193 schema:name Bone Tissue Regeneration Laboratory, Istituto Ortopedico Rizzoli, Bologna, Italy
194 Experimental Surgery, Istituto Ortopedico Rizzoli, Bologna, Italy
195 V Orthopedic Ward, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136, Bologna, Italy
196 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...