Comparison of Clinical Features Between Primary and Secondary Breast Diffuse Large B Cell Lymphoma: A Yokohama Cooperative Study Group for ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2020-06-23

AUTHORS

Hiroyuki Takahashi, Rika Sakai, Takayuki Sakuma, Ayako Matsumura, Kazuho Miyashita, Yoshimi Ishii, Yuki Nakajima, Ayumi Numata, Yukako Hattori, Takuya Miyazaki, Chizuko Hashimoto, Hideyuki Koharazawa, Sachiya Takemura, Jun Taguchi, Katsumichi Fujimaki, Hiroyuki Fujita, Hideaki Nakajima

ABSTRACT

We performed a retrospective analysis of DLBCL with breast involvement to compare the prognosis of primary breast lymphoma (PBL) to secondary breast lymphoma (SBL; especially in limited stage cases). We retrospectively reviewed records of 25 diffuse large B-cell lymphoma (DLBCL) patients with breast involvement who received chemotherapy between January 2000 and August 2012. We compared clinical features and prognosis among patients with PBL (n = 11), limited stage SBL (LSBL; n = 6), and advanced stage SBL (ASBL, n = 8). The PBL group had significantly lesser patients with breast tumours (BTs) > 5 cm than the SBL group (P = 0.02). After a median follow-up of 71.3 months, we observed significantly better 5-year overall survival (OS) in the PBL group (90.0%) than in the LSBL (33.3%, P = 0.01) group, but not for progression-free survival (PFS). Patients with BT > 5 cm had worse OS (P = 0.01) and PFS (P = 0.04) than those with BT ≤ 5 cm. PBL had a better prognosis than SBL among limited stage DLBCL. More... »

PAGES

60-66

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12288-020-01307-7

DOI

http://dx.doi.org/10.1007/s12288-020-01307-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1128717460

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/33707836


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