Fat necrosis after breast-conserving oncoplastic surgery View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-08-27

AUTHORS

Haruka Nakada, Masayuki Inoue, Kazushige Furuya, Hideki Watanabe, Kou Ikegame, Yuko Nakayama, Masato Ohmori, Hiroshi Nakagomi

ABSTRACT

BackgroundFat necrosis is a subjective early as well as delayed complication, which sometimes mimics local recurrence and ruins the quality of life by pain and poor cosmetic result. While, the frequency and severity of fat necrosis are important issues that breast surgeons should explain to the patient, these data are not revealed well.MethodsA total of 1476 patients who underwent breast surgery from January 2000 to December 2012 were enrolled in the present study. We assessed fat necrosis by mammographic and physical findings and created grading criteria: Grade (G) 0, no fat necrosis; G1, no symptomatic fat necrosis (mammographic dystrophic calcification); G2, mild symptomatic necrosis (mammographic dystrophic necrosis with tumor); G3, severe symptomatic necrosis (mammographic dystrophic necrosis with pain or skin change); and G4, symptomatic necrosis requiring surgical intervention.ResultsOf the 1476 patients enrolled, 393 (27%) underwent mastectomy, and 1083 (73%) underwent breast-conserving surgery. We achieved a high rate of breast-conserving surgery at a total rate of 73% over the study period and maximum rate of 88% in 2010, using oncoplastic procedures. We mainly adopted a pedicled fat flap (417/1083; 39%) and a free dermal fat flap (40/1083; 3.7%). Among the 626 patients who underwent partial resection with no replacement for the defect, G1–G2 fat necrosis was seen in 29/626 (4.6%). While, the incidence of fat necrosis with pedicled fat flap and free dermal fat graft was 68/417 (16%) and 40/40 (100%), respectively, showing a significant difference (p < 0.01). Furthermore, the incidence of G3–G4 fat necrosis was significantly higher with free dermal fat grafts (25%; 10/40) than with pedicled flap (2.9%; 12/417) (p < 0.01). Among pedicled flaps, the incidence of fat necrosis with inframammary adipofascial flaps was 56% (14/25) which was higher than that with lateral epidermal fat flaps (12%; 33/276) (p < 0.01), and rotation of surrounding breast tissues (8%; 21/116) (p < 0.01). The incidence of G3 fat necrosis was also high at 20% (5/25) in inframammary adipofascial flaps.ConclusionsBreast-conserving oncoplastic surgery carries a risk of fat necrosis as a delayed complication. The incidence rate and severity of fat necrosis with each procedure should be assessed. We should select fat grafts with a good blood supply to replace defects of breast-conserving therapy. More... »

PAGES

125-130

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12282-018-0901-5

DOI

http://dx.doi.org/10.1007/s12282-018-0901-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1106366362

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30151780


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adipose Tissue", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Breast", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Breast Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fat Necrosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Follow-Up Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Free Tissue Flaps", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Incidence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mammography", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mastectomy, Segmental", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Recurrence, Local", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Postoperative Complications", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Quality of Life", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Severity of Illness Index", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.417333.1", 
          "name": [
            "Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakada", 
        "givenName": "Haruka", 
        "id": "sg:person.01301466667.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301466667.87"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.417333.1", 
          "name": [
            "Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Inoue", 
        "givenName": "Masayuki", 
        "id": "sg:person.01354217107.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354217107.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.417333.1", 
          "name": [
            "Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Furuya", 
        "givenName": "Kazushige", 
        "id": "sg:person.01265174206.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265174206.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.417333.1", 
          "name": [
            "Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Watanabe", 
        "givenName": "Hideki", 
        "id": "sg:person.01233353467.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233353467.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.417333.1", 
          "name": [
            "Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ikegame", 
        "givenName": "Kou", 
        "id": "sg:person.016412731202.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016412731202.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "First Department of Surgery, University of Yamanashi, Yamanashi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.267500.6", 
          "name": [
            "First Department of Surgery, University of Yamanashi, Yamanashi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakayama", 
        "givenName": "Yuko", 
        "id": "sg:person.01301235631.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301235631.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "First Department of Surgery, University of Yamanashi, Yamanashi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.267500.6", 
          "name": [
            "First Department of Surgery, University of Yamanashi, Yamanashi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ohmori", 
        "givenName": "Masato", 
        "id": "sg:person.011047665465.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011047665465.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan", 
          "id": "http://www.grid.ac/institutes/grid.417333.1", 
          "name": [
            "Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakagomi", 
        "givenName": "Hiroshi", 
        "id": "sg:person.01152576336.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152576336.53"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s12282-012-0418-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048453393", 
          "https://doi.org/10.1007/s12282-012-0418-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.2325/jbcs.13.289", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016739434", 
          "https://doi.org/10.2325/jbcs.13.289"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.2325/jbcs.12.16", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023525971", 
          "https://doi.org/10.2325/jbcs.12.16"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12282-011-0285-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018656768", 
          "https://doi.org/10.1007/s12282-011-0285-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02967541", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035397879", 
          "https://doi.org/10.1007/bf02967541"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-009-0765-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027351885", 
          "https://doi.org/10.1245/s10434-009-0765-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12282-009-0104-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028185028", 
          "https://doi.org/10.1007/s12282-009-0104-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10549-013-2611-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004615144", 
          "https://doi.org/10.1007/s10549-013-2611-1"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-08-27", 
    "datePublishedReg": "2018-08-27", 
    "description": "BackgroundFat necrosis is a subjective early as well as delayed complication, which sometimes mimics local recurrence and ruins the quality of life by pain and poor cosmetic result. While, the frequency and severity of fat necrosis are important issues that breast surgeons should explain to the patient, these data are not revealed well.MethodsA total of 1476 patients who underwent breast surgery from January 2000 to December 2012 were enrolled in the present study. We assessed fat necrosis by mammographic and physical findings and created grading criteria: Grade (G) 0, no fat necrosis; G1, no symptomatic fat necrosis (mammographic dystrophic calcification); G2, mild symptomatic necrosis (mammographic dystrophic necrosis with tumor); G3, severe symptomatic necrosis (mammographic dystrophic necrosis with pain or skin change); and G4, symptomatic necrosis requiring surgical intervention.ResultsOf the 1476 patients enrolled, 393 (27%) underwent mastectomy, and 1083 (73%) underwent breast-conserving surgery. We achieved a high rate of breast-conserving surgery at a total rate of 73% over the study period and maximum rate of 88% in 2010, using oncoplastic procedures. We mainly adopted a pedicled fat flap (417/1083; 39%) and a free dermal fat flap (40/1083; 3.7%). Among the 626 patients who underwent partial resection with no replacement for the defect, G1\u2013G2 fat necrosis was seen in 29/626 (4.6%). While, the incidence of fat necrosis with pedicled fat flap and free dermal fat graft was 68/417 (16%) and 40/40 (100%), respectively, showing a significant difference (p\u2009<\u20090.01). Furthermore, the incidence of G3\u2013G4 fat necrosis was significantly higher with free dermal fat grafts (25%; 10/40) than with pedicled flap (2.9%; 12/417) (p\u2009<\u20090.01). Among pedicled flaps, the incidence of fat necrosis with inframammary adipofascial flaps was 56% (14/25) which was higher than that with lateral epidermal fat flaps (12%; 33/276) (p\u2009<\u20090.01), and rotation of surrounding breast tissues (8%; 21/116) (p\u2009<\u20090.01). The incidence of G3 fat necrosis was also high at 20% (5/25) in inframammary adipofascial flaps.ConclusionsBreast-conserving oncoplastic surgery carries a risk of fat necrosis as a delayed complication. The incidence rate and severity of fat necrosis with each procedure should be assessed. We should select fat grafts with a good blood supply to replace defects of breast-conserving therapy.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s12282-018-0901-5", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1021080", 
        "issn": [
          "1340-6868", 
          "1880-4233"
        ], 
        "name": "Breast Cancer", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "26"
      }
    ], 
    "keywords": [
      "free dermal fat graft", 
      "inframammary adipofascial flap", 
      "breast-conserving surgery", 
      "fat necrosis", 
      "dermal fat graft", 
      "symptomatic necrosis", 
      "fat grafts", 
      "fat flap", 
      "oncoplastic surgery", 
      "adipofascial flap", 
      "symptomatic fat necrosis", 
      "breast-conserving therapy", 
      "poor cosmetic results", 
      "good blood supply", 
      "quality of life", 
      "dermal fat flap", 
      "underwent mastectomy", 
      "local recurrence", 
      "partial resection", 
      "breast surgery", 
      "surgical intervention", 
      "oncoplastic procedures", 
      "cosmetic results", 
      "physical findings", 
      "grade 0", 
      "breast surgeons", 
      "incidence rate", 
      "blood supply", 
      "pedicled fat flap", 
      "surgery", 
      "pedicled flaps", 
      "patients", 
      "necrosis", 
      "breast tissue", 
      "study period", 
      "incidence", 
      "flap", 
      "graft", 
      "complications", 
      "grading criteria", 
      "significant differences", 
      "high rate", 
      "severity", 
      "present study", 
      "ConclusionsBreast", 
      "mastectomy", 
      "resection", 
      "pain", 
      "recurrence", 
      "ResultsOf", 
      "therapy", 
      "surgeons", 
      "rate", 
      "intervention", 
      "total rate", 
      "total", 
      "risk", 
      "tissue", 
      "defects", 
      "procedure", 
      "G3", 
      "G4", 
      "findings", 
      "G1", 
      "G2", 
      "replacement", 
      "period", 
      "differences", 
      "criteria", 
      "study", 
      "life", 
      "maximum rate", 
      "frequency", 
      "data", 
      "quality", 
      "results", 
      "important issue", 
      "supply", 
      "issues", 
      "rotation"
    ], 
    "name": "Fat necrosis after breast-conserving oncoplastic surgery", 
    "pagination": "125-130", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1106366362"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12282-018-0901-5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30151780"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12282-018-0901-5", 
      "https://app.dimensions.ai/details/publication/pub.1106366362"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-06-01T22:19", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220601/entities/gbq_results/article/article_765.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s12282-018-0901-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12282-018-0901-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12282-018-0901-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12282-018-0901-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12282-018-0901-5'


 

This table displays all metadata directly associated to this object as RDF triples.

290 TRIPLES      22 PREDICATES      130 URIs      114 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12282-018-0901-5 schema:about N15dfd47494b74e27a008a8762d96c8a6
2 N277ed444a4934d159dad15c4ef4c26be
3 N27a9afa0463e49278c8bf34f16fff8d2
4 N5044e080e4e842f8b012ce16a5f4905f
5 N633e3e44323d49fa8ee383ef91ab7357
6 N70a5ab9101284f9191b8a1a527dc82b1
7 N77c5ad65285049158f924934ce14d1f6
8 N987b82945af34dcfa36f21d8f9f832d0
9 Na9b9c233e44d4fafa8fc88061ecdcc20
10 Nce7c761dea074bed807867ef38df21ab
11 Ncfa7db6506534a54a8cd78e8cbc15b1c
12 Nd85fca63b40d4020a808f98d102aca39
13 Ne09baf2d08954845b8963ddf20085f93
14 Ne3e9d38144144211a778bd6cf9b808c3
15 Nefe8417664464af5b394a619537c7770
16 Nfb7caed023c54798ac8f5dafa8fe4ff6
17 anzsrc-for:11
18 anzsrc-for:1103
19 schema:author Nd28324a4bbc14c2ab6f2e98d01dd0ef7
20 schema:citation sg:pub.10.1007/bf02967541
21 sg:pub.10.1007/s10549-013-2611-1
22 sg:pub.10.1007/s12282-009-0104-1
23 sg:pub.10.1007/s12282-011-0285-2
24 sg:pub.10.1007/s12282-012-0418-2
25 sg:pub.10.1245/s10434-009-0765-1
26 sg:pub.10.2325/jbcs.12.16
27 sg:pub.10.2325/jbcs.13.289
28 schema:datePublished 2018-08-27
29 schema:datePublishedReg 2018-08-27
30 schema:description BackgroundFat necrosis is a subjective early as well as delayed complication, which sometimes mimics local recurrence and ruins the quality of life by pain and poor cosmetic result. While, the frequency and severity of fat necrosis are important issues that breast surgeons should explain to the patient, these data are not revealed well.MethodsA total of 1476 patients who underwent breast surgery from January 2000 to December 2012 were enrolled in the present study. We assessed fat necrosis by mammographic and physical findings and created grading criteria: Grade (G) 0, no fat necrosis; G1, no symptomatic fat necrosis (mammographic dystrophic calcification); G2, mild symptomatic necrosis (mammographic dystrophic necrosis with tumor); G3, severe symptomatic necrosis (mammographic dystrophic necrosis with pain or skin change); and G4, symptomatic necrosis requiring surgical intervention.ResultsOf the 1476 patients enrolled, 393 (27%) underwent mastectomy, and 1083 (73%) underwent breast-conserving surgery. We achieved a high rate of breast-conserving surgery at a total rate of 73% over the study period and maximum rate of 88% in 2010, using oncoplastic procedures. We mainly adopted a pedicled fat flap (417/1083; 39%) and a free dermal fat flap (40/1083; 3.7%). Among the 626 patients who underwent partial resection with no replacement for the defect, G1–G2 fat necrosis was seen in 29/626 (4.6%). While, the incidence of fat necrosis with pedicled fat flap and free dermal fat graft was 68/417 (16%) and 40/40 (100%), respectively, showing a significant difference (p < 0.01). Furthermore, the incidence of G3–G4 fat necrosis was significantly higher with free dermal fat grafts (25%; 10/40) than with pedicled flap (2.9%; 12/417) (p < 0.01). Among pedicled flaps, the incidence of fat necrosis with inframammary adipofascial flaps was 56% (14/25) which was higher than that with lateral epidermal fat flaps (12%; 33/276) (p < 0.01), and rotation of surrounding breast tissues (8%; 21/116) (p < 0.01). The incidence of G3 fat necrosis was also high at 20% (5/25) in inframammary adipofascial flaps.ConclusionsBreast-conserving oncoplastic surgery carries a risk of fat necrosis as a delayed complication. The incidence rate and severity of fat necrosis with each procedure should be assessed. We should select fat grafts with a good blood supply to replace defects of breast-conserving therapy.
31 schema:genre article
32 schema:inLanguage en
33 schema:isAccessibleForFree false
34 schema:isPartOf Nb10704629f654cdfa2f7d8535acf9987
35 Nbc911a3085384056ab2c77266d065425
36 sg:journal.1021080
37 schema:keywords ConclusionsBreast
38 G1
39 G2
40 G3
41 G4
42 ResultsOf
43 adipofascial flap
44 blood supply
45 breast surgeons
46 breast surgery
47 breast tissue
48 breast-conserving surgery
49 breast-conserving therapy
50 complications
51 cosmetic results
52 criteria
53 data
54 defects
55 dermal fat flap
56 dermal fat graft
57 differences
58 fat flap
59 fat grafts
60 fat necrosis
61 findings
62 flap
63 free dermal fat graft
64 frequency
65 good blood supply
66 grade 0
67 grading criteria
68 graft
69 high rate
70 important issue
71 incidence
72 incidence rate
73 inframammary adipofascial flap
74 intervention
75 issues
76 life
77 local recurrence
78 mastectomy
79 maximum rate
80 necrosis
81 oncoplastic procedures
82 oncoplastic surgery
83 pain
84 partial resection
85 patients
86 pedicled fat flap
87 pedicled flaps
88 period
89 physical findings
90 poor cosmetic results
91 present study
92 procedure
93 quality
94 quality of life
95 rate
96 recurrence
97 replacement
98 resection
99 results
100 risk
101 rotation
102 severity
103 significant differences
104 study
105 study period
106 supply
107 surgeons
108 surgery
109 surgical intervention
110 symptomatic fat necrosis
111 symptomatic necrosis
112 therapy
113 tissue
114 total
115 total rate
116 underwent mastectomy
117 schema:name Fat necrosis after breast-conserving oncoplastic surgery
118 schema:pagination 125-130
119 schema:productId Naa748fb4182846f18db55aef36b07fb7
120 Nb47cc8d305b54dc6b69dab7d41cca132
121 Ncce830377bfb44b88255362dcc87eadb
122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106366362
123 https://doi.org/10.1007/s12282-018-0901-5
124 schema:sdDatePublished 2022-06-01T22:19
125 schema:sdLicense https://scigraph.springernature.com/explorer/license/
126 schema:sdPublisher N59157155b1454bdf916abad1b6e32074
127 schema:url https://doi.org/10.1007/s12282-018-0901-5
128 sgo:license sg:explorer/license/
129 sgo:sdDataset articles
130 rdf:type schema:ScholarlyArticle
131 N14ef1465a0a94553abc8d00ee73475b9 rdf:first sg:person.016412731202.58
132 rdf:rest N7e610a341a0f45a4825b89292f457761
133 N15dfd47494b74e27a008a8762d96c8a6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Fat Necrosis
135 rdf:type schema:DefinedTerm
136 N277ed444a4934d159dad15c4ef4c26be schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Mammography
138 rdf:type schema:DefinedTerm
139 N27a9afa0463e49278c8bf34f16fff8d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Treatment Outcome
141 rdf:type schema:DefinedTerm
142 N33a15dc5446a49929d2b1f82e96cfe42 rdf:first sg:person.011047665465.00
143 rdf:rest N5c6f7591f5d041d4bddc45534d87f477
144 N3bfd4aa45acd456ea211e1cb2a944844 rdf:first sg:person.01265174206.02
145 rdf:rest Nb0f5497b700147f49ea2e60af0baab02
146 N5044e080e4e842f8b012ce16a5f4905f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Breast Neoplasms
148 rdf:type schema:DefinedTerm
149 N59157155b1454bdf916abad1b6e32074 schema:name Springer Nature - SN SciGraph project
150 rdf:type schema:Organization
151 N5c6f7591f5d041d4bddc45534d87f477 rdf:first sg:person.01152576336.53
152 rdf:rest rdf:nil
153 N633e3e44323d49fa8ee383ef91ab7357 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Neoplasm Recurrence, Local
155 rdf:type schema:DefinedTerm
156 N70a5ab9101284f9191b8a1a527dc82b1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Female
158 rdf:type schema:DefinedTerm
159 N73d7b00b901845f7aab0941514e46728 rdf:first sg:person.01354217107.78
160 rdf:rest N3bfd4aa45acd456ea211e1cb2a944844
161 N77c5ad65285049158f924934ce14d1f6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Follow-Up Studies
163 rdf:type schema:DefinedTerm
164 N7e610a341a0f45a4825b89292f457761 rdf:first sg:person.01301235631.15
165 rdf:rest N33a15dc5446a49929d2b1f82e96cfe42
166 N987b82945af34dcfa36f21d8f9f832d0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Postoperative Complications
168 rdf:type schema:DefinedTerm
169 Na9b9c233e44d4fafa8fc88061ecdcc20 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Mastectomy, Segmental
171 rdf:type schema:DefinedTerm
172 Naa748fb4182846f18db55aef36b07fb7 schema:name pubmed_id
173 schema:value 30151780
174 rdf:type schema:PropertyValue
175 Nb0f5497b700147f49ea2e60af0baab02 rdf:first sg:person.01233353467.08
176 rdf:rest N14ef1465a0a94553abc8d00ee73475b9
177 Nb10704629f654cdfa2f7d8535acf9987 schema:issueNumber 1
178 rdf:type schema:PublicationIssue
179 Nb47cc8d305b54dc6b69dab7d41cca132 schema:name dimensions_id
180 schema:value pub.1106366362
181 rdf:type schema:PropertyValue
182 Nbc911a3085384056ab2c77266d065425 schema:volumeNumber 26
183 rdf:type schema:PublicationVolume
184 Ncce830377bfb44b88255362dcc87eadb schema:name doi
185 schema:value 10.1007/s12282-018-0901-5
186 rdf:type schema:PropertyValue
187 Nce7c761dea074bed807867ef38df21ab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
188 schema:name Severity of Illness Index
189 rdf:type schema:DefinedTerm
190 Ncfa7db6506534a54a8cd78e8cbc15b1c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
191 schema:name Adipose Tissue
192 rdf:type schema:DefinedTerm
193 Nd28324a4bbc14c2ab6f2e98d01dd0ef7 rdf:first sg:person.01301466667.87
194 rdf:rest N73d7b00b901845f7aab0941514e46728
195 Nd85fca63b40d4020a808f98d102aca39 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
196 schema:name Breast
197 rdf:type schema:DefinedTerm
198 Ne09baf2d08954845b8963ddf20085f93 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
199 schema:name Quality of Life
200 rdf:type schema:DefinedTerm
201 Ne3e9d38144144211a778bd6cf9b808c3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
202 schema:name Humans
203 rdf:type schema:DefinedTerm
204 Nefe8417664464af5b394a619537c7770 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
205 schema:name Free Tissue Flaps
206 rdf:type schema:DefinedTerm
207 Nfb7caed023c54798ac8f5dafa8fe4ff6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
208 schema:name Incidence
209 rdf:type schema:DefinedTerm
210 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
211 schema:name Medical and Health Sciences
212 rdf:type schema:DefinedTerm
213 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
214 schema:name Clinical Sciences
215 rdf:type schema:DefinedTerm
216 sg:journal.1021080 schema:issn 1340-6868
217 1880-4233
218 schema:name Breast Cancer
219 schema:publisher Springer Nature
220 rdf:type schema:Periodical
221 sg:person.011047665465.00 schema:affiliation grid-institutes:grid.267500.6
222 schema:familyName Ohmori
223 schema:givenName Masato
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011047665465.00
225 rdf:type schema:Person
226 sg:person.01152576336.53 schema:affiliation grid-institutes:grid.417333.1
227 schema:familyName Nakagomi
228 schema:givenName Hiroshi
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152576336.53
230 rdf:type schema:Person
231 sg:person.01233353467.08 schema:affiliation grid-institutes:grid.417333.1
232 schema:familyName Watanabe
233 schema:givenName Hideki
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01233353467.08
235 rdf:type schema:Person
236 sg:person.01265174206.02 schema:affiliation grid-institutes:grid.417333.1
237 schema:familyName Furuya
238 schema:givenName Kazushige
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265174206.02
240 rdf:type schema:Person
241 sg:person.01301235631.15 schema:affiliation grid-institutes:grid.267500.6
242 schema:familyName Nakayama
243 schema:givenName Yuko
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301235631.15
245 rdf:type schema:Person
246 sg:person.01301466667.87 schema:affiliation grid-institutes:grid.417333.1
247 schema:familyName Nakada
248 schema:givenName Haruka
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01301466667.87
250 rdf:type schema:Person
251 sg:person.01354217107.78 schema:affiliation grid-institutes:grid.417333.1
252 schema:familyName Inoue
253 schema:givenName Masayuki
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354217107.78
255 rdf:type schema:Person
256 sg:person.016412731202.58 schema:affiliation grid-institutes:grid.417333.1
257 schema:familyName Ikegame
258 schema:givenName Kou
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016412731202.58
260 rdf:type schema:Person
261 sg:pub.10.1007/bf02967541 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035397879
262 https://doi.org/10.1007/bf02967541
263 rdf:type schema:CreativeWork
264 sg:pub.10.1007/s10549-013-2611-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004615144
265 https://doi.org/10.1007/s10549-013-2611-1
266 rdf:type schema:CreativeWork
267 sg:pub.10.1007/s12282-009-0104-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028185028
268 https://doi.org/10.1007/s12282-009-0104-1
269 rdf:type schema:CreativeWork
270 sg:pub.10.1007/s12282-011-0285-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018656768
271 https://doi.org/10.1007/s12282-011-0285-2
272 rdf:type schema:CreativeWork
273 sg:pub.10.1007/s12282-012-0418-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048453393
274 https://doi.org/10.1007/s12282-012-0418-2
275 rdf:type schema:CreativeWork
276 sg:pub.10.1245/s10434-009-0765-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027351885
277 https://doi.org/10.1245/s10434-009-0765-1
278 rdf:type schema:CreativeWork
279 sg:pub.10.2325/jbcs.12.16 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023525971
280 https://doi.org/10.2325/jbcs.12.16
281 rdf:type schema:CreativeWork
282 sg:pub.10.2325/jbcs.13.289 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016739434
283 https://doi.org/10.2325/jbcs.13.289
284 rdf:type schema:CreativeWork
285 grid-institutes:grid.267500.6 schema:alternateName First Department of Surgery, University of Yamanashi, Yamanashi, Japan
286 schema:name First Department of Surgery, University of Yamanashi, Yamanashi, Japan
287 rdf:type schema:Organization
288 grid-institutes:grid.417333.1 schema:alternateName Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan
289 schema:name Department of Breast Surgery, Yamanashi Prefectural Central Hospital, Fujimi1-1-1, 400-8506, Kofu, Yamanashi, Japan
290 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...