The intracellular mechanism of action on Escherichia coli of BF2-A/C, two analogues of the antimicrobial peptide Buforin 2 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-04

AUTHORS

Gang Hao, Yong-Hui Shi, Ya-Li Tang, Guo-Wei Le

ABSTRACT

In the present study, the antimicrobial peptides BF2-A and BF2-C, two analogues of Buforin 2, were chemically synthesized and the activities were assayed. To elucidate the bactericidal mechanism of BF2-A/C and their different antimicrobial activities, the influence of peptides to E. coli cell membrane and targets of intracellular action were researched. Obviously, BF2-A and BF2-C did not induce the influx of PI into the E. coli cells, indicating nonmemebrane permeabilizing killing action. The FITC-labeled BF2-A/C could penetrate the E. coli cell membrane and BF2-C penetrated the cells more efficiently. Furthermore, BF2-A/C could bind to DNA and RNA respectively, and the affinity of BF2-C to DNA was powerful at least over 4 times than that of BF2-A. The present results implied that BF2-A and BF2-C inhibited the cellular functions by binding to DNA and RNA of cells after penetrating the cell membranes, resulting in the rapid cell death. The structure-activity relationship analysis of BF2-A/C revealed that the cell-penetrating efficiency and the affinity ability to DNA were critical factors for determining the antimicrobial potency of both peptides. The more efficient cell-penetrating and stronger affinity to DNA caused that BF2-C displayed more excellent antimicrobial activity and rapid killing kinetics than BF2-A. More... »

PAGES

200-206

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12275-013-2441-1

DOI

http://dx.doi.org/10.1007/s12275-013-2441-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1016014169

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23625221


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antimicrobial Cationic Peptides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bacteria", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Escherichia coli", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microbial Viability", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proteins", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Jiangnan University", 
          "id": "https://www.grid.ac/institutes/grid.258151.a", 
          "name": [
            "College of Life Science and Technology, Southwest University for Nationalities, 610041, ChengDu, Sichuan Province, P. R. China", 
            "Institute of Food Nutrition and Safety, School of Food Science and Technology, JiangNan University, 214122, WuXi, Jiangsu Province, P. R. China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hao", 
        "givenName": "Gang", 
        "id": "sg:person.01342161237.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342161237.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Jiangnan University", 
          "id": "https://www.grid.ac/institutes/grid.258151.a", 
          "name": [
            "Institute of Food Nutrition and Safety, School of Food Science and Technology, JiangNan University, 214122, WuXi, Jiangsu Province, P. R. China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shi", 
        "givenName": "Yong-Hui", 
        "id": "sg:person.0674200354.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674200354.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Jiangnan University", 
          "id": "https://www.grid.ac/institutes/grid.258151.a", 
          "name": [
            "Institute of Food Nutrition and Safety, School of Food Science and Technology, JiangNan University, 214122, WuXi, Jiangsu Province, P. R. China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tang", 
        "givenName": "Ya-Li", 
        "id": "sg:person.0615037363.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615037363.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Jiangnan University", 
          "id": "https://www.grid.ac/institutes/grid.258151.a", 
          "name": [
            "Institute of Food Nutrition and Safety, School of Food Science and Technology, JiangNan University, 214122, WuXi, Jiangsu Province, P. R. China"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Le", 
        "givenName": "Guo-Wei", 
        "id": "sg:person.016101750457.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016101750457.19"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1073/pnas.150518097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000809909"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1574-6968.2004.tb09720.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001121313"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1574-6968.2004.tb09720.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001121313"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.peptides.2009.05.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001705624"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3011.1990.tb00939.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006229141"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3011.1990.tb00939.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006229141"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.febslet.2008.06.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011261580"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.foodchem.2008.12.102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012187672"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.1996.0071", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013929720"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1980.tb05991.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014666330"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0304-4157(98)00014-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015707032"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/237232a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016256854", 
          "https://doi.org/10.1038/237232a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.2002.6548", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018091492"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1574-6968.1998.tb12896.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020948514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1574-6968.1998.tb12896.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020948514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.febslet.2006.01.041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022121501"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.febslet.2008.04.036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024119418"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.46.4.1059-1066.2002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029767232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2006.08.094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032030979"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/psc.926", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032917616"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.1998.8159", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034817946"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1982.tb06858.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037957183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0005-2736(99)00197-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042283992"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0005-2736(99)00200-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044519656"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jbiotec.2006.02.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049306049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00126a022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055161887"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi002656a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055167706"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi002656a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055167706"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi048206q", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055198994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi048206q", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055198994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi9904104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055217558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi9904104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055217558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082839690", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-04", 
    "datePublishedReg": "2013-04-01", 
    "description": "In the present study, the antimicrobial peptides BF2-A and BF2-C, two analogues of Buforin 2, were chemically synthesized and the activities were assayed. To elucidate the bactericidal mechanism of BF2-A/C and their different antimicrobial activities, the influence of peptides to E. coli cell membrane and targets of intracellular action were researched. Obviously, BF2-A and BF2-C did not induce the influx of PI into the E. coli cells, indicating nonmemebrane permeabilizing killing action. The FITC-labeled BF2-A/C could penetrate the E. coli cell membrane and BF2-C penetrated the cells more efficiently. Furthermore, BF2-A/C could bind to DNA and RNA respectively, and the affinity of BF2-C to DNA was powerful at least over 4 times than that of BF2-A. The present results implied that BF2-A and BF2-C inhibited the cellular functions by binding to DNA and RNA of cells after penetrating the cell membranes, resulting in the rapid cell death. The structure-activity relationship analysis of BF2-A/C revealed that the cell-penetrating efficiency and the affinity ability to DNA were critical factors for determining the antimicrobial potency of both peptides. The more efficient cell-penetrating and stronger affinity to DNA caused that BF2-C displayed more excellent antimicrobial activity and rapid killing kinetics than BF2-A.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s12275-013-2441-1", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1116533", 
        "issn": [
          "1225-8873", 
          "1976-3794"
        ], 
        "name": "Journal of Microbiology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "51"
      }
    ], 
    "name": "The intracellular mechanism of action on Escherichia coli of BF2-A/C, two analogues of the antimicrobial peptide Buforin 2", 
    "pagination": "200-206", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "4c4dfcec57d9601085820fd87d46b41768b2ee3d092d2359bd44860003b2465c"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "23625221"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9703165"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12275-013-2441-1"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1016014169"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12275-013-2441-1", 
      "https://app.dimensions.ai/details/publication/pub.1016014169"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T18:22", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8675_00000521.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs12275-013-2441-1"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12275-013-2441-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12275-013-2441-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12275-013-2441-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12275-013-2441-1'


 

This table displays all metadata directly associated to this object as RDF triples.

192 TRIPLES      21 PREDICATES      61 URIs      26 LITERALS      14 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12275-013-2441-1 schema:about N3134dea133994d42b7cc373bfe670fdd
2 N47505c7351b94d84be42ce08dc3847bb
3 N5d0db0cdf34f4064af73e98a5816e5ec
4 Naa4598bb8e1745e09ac5e2a6c301e356
5 Nb486d3ff136e4e02acf83df5cb3c338a
6 anzsrc-for:06
7 anzsrc-for:0601
8 schema:author N66caf34772934e1494851e9b9832633e
9 schema:citation sg:pub.10.1038/237232a0
10 https://app.dimensions.ai/details/publication/pub.1082839690
11 https://doi.org/10.1002/psc.926
12 https://doi.org/10.1006/bbrc.1996.0071
13 https://doi.org/10.1006/bbrc.1998.8159
14 https://doi.org/10.1006/bbrc.2002.6548
15 https://doi.org/10.1016/j.bbrc.2006.08.094
16 https://doi.org/10.1016/j.febslet.2006.01.041
17 https://doi.org/10.1016/j.febslet.2008.04.036
18 https://doi.org/10.1016/j.febslet.2008.06.015
19 https://doi.org/10.1016/j.foodchem.2008.12.102
20 https://doi.org/10.1016/j.jbiotec.2006.02.010
21 https://doi.org/10.1016/j.peptides.2009.05.016
22 https://doi.org/10.1016/s0005-2736(99)00197-2
23 https://doi.org/10.1016/s0005-2736(99)00200-x
24 https://doi.org/10.1016/s0304-4157(98)00014-8
25 https://doi.org/10.1021/bi00126a022
26 https://doi.org/10.1021/bi002656a
27 https://doi.org/10.1021/bi048206q
28 https://doi.org/10.1021/bi9904104
29 https://doi.org/10.1073/pnas.150518097
30 https://doi.org/10.1111/j.1399-3011.1990.tb00939.x
31 https://doi.org/10.1111/j.1432-1033.1980.tb05991.x
32 https://doi.org/10.1111/j.1432-1033.1982.tb06858.x
33 https://doi.org/10.1111/j.1574-6968.1998.tb12896.x
34 https://doi.org/10.1111/j.1574-6968.2004.tb09720.x
35 https://doi.org/10.1128/aac.46.4.1059-1066.2002
36 schema:datePublished 2013-04
37 schema:datePublishedReg 2013-04-01
38 schema:description In the present study, the antimicrobial peptides BF2-A and BF2-C, two analogues of Buforin 2, were chemically synthesized and the activities were assayed. To elucidate the bactericidal mechanism of BF2-A/C and their different antimicrobial activities, the influence of peptides to E. coli cell membrane and targets of intracellular action were researched. Obviously, BF2-A and BF2-C did not induce the influx of PI into the E. coli cells, indicating nonmemebrane permeabilizing killing action. The FITC-labeled BF2-A/C could penetrate the E. coli cell membrane and BF2-C penetrated the cells more efficiently. Furthermore, BF2-A/C could bind to DNA and RNA respectively, and the affinity of BF2-C to DNA was powerful at least over 4 times than that of BF2-A. The present results implied that BF2-A and BF2-C inhibited the cellular functions by binding to DNA and RNA of cells after penetrating the cell membranes, resulting in the rapid cell death. The structure-activity relationship analysis of BF2-A/C revealed that the cell-penetrating efficiency and the affinity ability to DNA were critical factors for determining the antimicrobial potency of both peptides. The more efficient cell-penetrating and stronger affinity to DNA caused that BF2-C displayed more excellent antimicrobial activity and rapid killing kinetics than BF2-A.
39 schema:genre research_article
40 schema:inLanguage en
41 schema:isAccessibleForFree false
42 schema:isPartOf N773196101d004eef86561efcaa3bcf6e
43 N784bb812c7844087b50d9147bdd1e5e3
44 sg:journal.1116533
45 schema:name The intracellular mechanism of action on Escherichia coli of BF2-A/C, two analogues of the antimicrobial peptide Buforin 2
46 schema:pagination 200-206
47 schema:productId N1ea36e0815284fe5888509775f28c89b
48 N320e3646658d4981b736761647b37868
49 N5bfc784467e54c7b8897706419ba4daa
50 Nb977c0ca4f3d49759383afef88d12a78
51 Ncb63b8885b6348009b6b39c022ce02bd
52 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016014169
53 https://doi.org/10.1007/s12275-013-2441-1
54 schema:sdDatePublished 2019-04-10T18:22
55 schema:sdLicense https://scigraph.springernature.com/explorer/license/
56 schema:sdPublisher N5235076c79454ab6b7e25c5538952335
57 schema:url http://link.springer.com/10.1007%2Fs12275-013-2441-1
58 sgo:license sg:explorer/license/
59 sgo:sdDataset articles
60 rdf:type schema:ScholarlyArticle
61 N1ea36e0815284fe5888509775f28c89b schema:name nlm_unique_id
62 schema:value 9703165
63 rdf:type schema:PropertyValue
64 N3134dea133994d42b7cc373bfe670fdd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
65 schema:name Escherichia coli
66 rdf:type schema:DefinedTerm
67 N320e3646658d4981b736761647b37868 schema:name pubmed_id
68 schema:value 23625221
69 rdf:type schema:PropertyValue
70 N47505c7351b94d84be42ce08dc3847bb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
71 schema:name Microbial Viability
72 rdf:type schema:DefinedTerm
73 N5235076c79454ab6b7e25c5538952335 schema:name Springer Nature - SN SciGraph project
74 rdf:type schema:Organization
75 N5bfc784467e54c7b8897706419ba4daa schema:name dimensions_id
76 schema:value pub.1016014169
77 rdf:type schema:PropertyValue
78 N5d0db0cdf34f4064af73e98a5816e5ec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Proteins
80 rdf:type schema:DefinedTerm
81 N66caf34772934e1494851e9b9832633e rdf:first sg:person.01342161237.63
82 rdf:rest N7be61e72771946dca785fb5d2dd5b400
83 N7334b683909e463b81b972b13176bc8d rdf:first sg:person.0615037363.67
84 rdf:rest Nd8a8de87cd684660922ca81f8b29f2b9
85 N773196101d004eef86561efcaa3bcf6e schema:issueNumber 2
86 rdf:type schema:PublicationIssue
87 N784bb812c7844087b50d9147bdd1e5e3 schema:volumeNumber 51
88 rdf:type schema:PublicationVolume
89 N7be61e72771946dca785fb5d2dd5b400 rdf:first sg:person.0674200354.07
90 rdf:rest N7334b683909e463b81b972b13176bc8d
91 Naa4598bb8e1745e09ac5e2a6c301e356 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Antimicrobial Cationic Peptides
93 rdf:type schema:DefinedTerm
94 Nb486d3ff136e4e02acf83df5cb3c338a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Bacteria
96 rdf:type schema:DefinedTerm
97 Nb977c0ca4f3d49759383afef88d12a78 schema:name readcube_id
98 schema:value 4c4dfcec57d9601085820fd87d46b41768b2ee3d092d2359bd44860003b2465c
99 rdf:type schema:PropertyValue
100 Ncb63b8885b6348009b6b39c022ce02bd schema:name doi
101 schema:value 10.1007/s12275-013-2441-1
102 rdf:type schema:PropertyValue
103 Nd8a8de87cd684660922ca81f8b29f2b9 rdf:first sg:person.016101750457.19
104 rdf:rest rdf:nil
105 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
106 schema:name Biological Sciences
107 rdf:type schema:DefinedTerm
108 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
109 schema:name Biochemistry and Cell Biology
110 rdf:type schema:DefinedTerm
111 sg:journal.1116533 schema:issn 1225-8873
112 1976-3794
113 schema:name Journal of Microbiology
114 rdf:type schema:Periodical
115 sg:person.01342161237.63 schema:affiliation https://www.grid.ac/institutes/grid.258151.a
116 schema:familyName Hao
117 schema:givenName Gang
118 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01342161237.63
119 rdf:type schema:Person
120 sg:person.016101750457.19 schema:affiliation https://www.grid.ac/institutes/grid.258151.a
121 schema:familyName Le
122 schema:givenName Guo-Wei
123 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016101750457.19
124 rdf:type schema:Person
125 sg:person.0615037363.67 schema:affiliation https://www.grid.ac/institutes/grid.258151.a
126 schema:familyName Tang
127 schema:givenName Ya-Li
128 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615037363.67
129 rdf:type schema:Person
130 sg:person.0674200354.07 schema:affiliation https://www.grid.ac/institutes/grid.258151.a
131 schema:familyName Shi
132 schema:givenName Yong-Hui
133 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674200354.07
134 rdf:type schema:Person
135 sg:pub.10.1038/237232a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016256854
136 https://doi.org/10.1038/237232a0
137 rdf:type schema:CreativeWork
138 https://app.dimensions.ai/details/publication/pub.1082839690 schema:CreativeWork
139 https://doi.org/10.1002/psc.926 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032917616
140 rdf:type schema:CreativeWork
141 https://doi.org/10.1006/bbrc.1996.0071 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013929720
142 rdf:type schema:CreativeWork
143 https://doi.org/10.1006/bbrc.1998.8159 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034817946
144 rdf:type schema:CreativeWork
145 https://doi.org/10.1006/bbrc.2002.6548 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018091492
146 rdf:type schema:CreativeWork
147 https://doi.org/10.1016/j.bbrc.2006.08.094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032030979
148 rdf:type schema:CreativeWork
149 https://doi.org/10.1016/j.febslet.2006.01.041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022121501
150 rdf:type schema:CreativeWork
151 https://doi.org/10.1016/j.febslet.2008.04.036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024119418
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1016/j.febslet.2008.06.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011261580
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1016/j.foodchem.2008.12.102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012187672
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1016/j.jbiotec.2006.02.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049306049
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1016/j.peptides.2009.05.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001705624
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1016/s0005-2736(99)00197-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042283992
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1016/s0005-2736(99)00200-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1044519656
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1016/s0304-4157(98)00014-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015707032
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1021/bi00126a022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055161887
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1021/bi002656a schema:sameAs https://app.dimensions.ai/details/publication/pub.1055167706
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1021/bi048206q schema:sameAs https://app.dimensions.ai/details/publication/pub.1055198994
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1021/bi9904104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055217558
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1073/pnas.150518097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000809909
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1111/j.1399-3011.1990.tb00939.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006229141
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1111/j.1432-1033.1980.tb05991.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014666330
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1111/j.1432-1033.1982.tb06858.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1037957183
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1111/j.1574-6968.1998.tb12896.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020948514
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1111/j.1574-6968.2004.tb09720.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001121313
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1128/aac.46.4.1059-1066.2002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029767232
188 rdf:type schema:CreativeWork
189 https://www.grid.ac/institutes/grid.258151.a schema:alternateName Jiangnan University
190 schema:name College of Life Science and Technology, Southwest University for Nationalities, 610041, ChengDu, Sichuan Province, P. R. China
191 Institute of Food Nutrition and Safety, School of Food Science and Technology, JiangNan University, 214122, WuXi, Jiangsu Province, P. R. China
192 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...