Bioconjugated silica nanoparticles: Development and applications View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-07-31

AUTHORS

Lin Wang, Wenjun Zhao, Weihong Tan

ABSTRACT

Advanced bioanalysis, including accurate quantitation, has driven the need to understand biology and medicine at the molecular level. Bioconjugated silica nanoparticles have the potential to address this emerging challenge. Particularly intriguing diagnostic and therapeutic applications in cancer and infectious disease as well as uses in gene and drug delivery, have also been found for silica nanoparticles. In this review, we describe the synthesis, bioconjugation, and applications of silica nanoparticles in different bioanalysis formats, such as selective tagging, barcoding, and separation of a wide range of biomedically important targets. Overall, we envisage that further development of these nanoparticles will provide a variety of advanced tools for molecular biology, genomics, proteomics and medicine. More... »

PAGES

99-115

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12274-008-8018-3

DOI

http://dx.doi.org/10.1007/s12274-008-8018-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022418134


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