Endoperoxy and hydroperoxy cadinane-type sesquiterpenoids from an Okinawan soft coral, Sinularia sp. View Full Text


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Article Info

DATE

2016-06

AUTHORS

Prodip K. Roy, Runa Ashimine, Haruna Miyazato, Junsei Taira, Katsuhiro Ueda

ABSTRACT

Three cadinane-type sesquiterpenoids, endoperoxide (1) and hydroperoxides (2, 3) together with three known sesquiterpenoids (4-6) were isolated from an Okinawan soft coral, Sinularia species. Structures of these isolates were elucidated by spectroscopic analyses (NMR, IR and MS) and molecular modeling. In addition, the isolates 1-3 as new compounds were examined for biological activities, resulting that they have antibacterial activity and weak cytotoxicity against HCT116 cells as well as anti-inflammatory effect on LPS/IFN-γ-stimulated RAW 264.7 macrophage cells. More... »

PAGES

778-784

References to SciGraph publications

  • 2012-05. Bioactive cadinane-type compounds from the soft coral Sinularia scabra in ARCHIVES OF PHARMACAL RESEARCH
  • 2008-10. A new sesquiterpene from Artemisia vulgaris in JOURNAL OF NATURAL MEDICINES
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12272-016-0759-z

    DOI

    http://dx.doi.org/10.1007/s12272-016-0759-z

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/27230778


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