Implant-Based Breast Reconstruction with Autologous Lower Dermal Sling and Radiation Therapy Outcomes View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-01-07

AUTHORS

Chaitanyanand B. Koppiker, Aijaz Ul Noor, Santosh Dixit, Ravindra Mahajan, Gautam Sharan, Upendra Dhar, Laleh Busheri, Smeeta Nare

ABSTRACT

Immediate breast reconstruction surgery (IBRS) with a sub-pectoral placement of implant improves quality of life of patients undergoing a mastectomy. Implant-based IBRS with autologous lower dermal sling (ALDS) procedure provides an effective surgical alternative to acellular dermal matrices. However, the influence of this procedure on radiation therapy (RT) outcomes remains unclear. This study aims at investigating post-surgery complications after 1 year in patients who have undergone IBRS-ALDS and RT. In this single-institution retrospective study, 78 implant-based IBRS patients with data available for a minimum of 1-year follow-up were stratified into group A (n = 40; IBRS) and group B (n = 38; IBRS + RT). Based on the use of ALDS procedure, group A patients were further stratified into sub-groups A1 (conventional IBRS; n = 21) and A2 (ALDS-IBRS; n = 19). Similarly, group B patients were sub-stratified into sub-groups B1 (conventional IBRS + RT; n = 18) and B2 (ALDS-IBRS + RT; n = 20). Clinical assessment and patient-reported outcome measures (PROMs) after 1-year post-surgery were conducted using Baker classification and BREAST-Q questionnaire, respectively. Patients in sub-group B1 exhibited higher percentages of overall major complications (41.6%) when compared to sub-group B2 (8.2%). Capsular contracture (12.5%) and reconstruction failure (20.8%) rates were higher for sub-group B1 vis-a-vis sub-group B2. Superior breast reconstruction outcomes with psycho-social well-being were observed in group B patients in comparison to group A (p < 0.05). Preliminary outcomes after a 1-year follow-up indicate that patients undergoing ALDS-IBRS exhibit reduced rate of RT-associated complications. IBRS-ALDS may obviate the need of ADMs in low-resource settings. More... »

PAGES

543-551

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12262-018-1856-7

DOI

http://dx.doi.org/10.1007/s12262-018-1856-7

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https://app.dimensions.ai/details/publication/pub.1111246903


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