Clinical features at transformation in adult T-cell leukemia–lymphoma with smoldering and chronic types View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04

AUTHORS

Hiroaki Taniguchi, Yoshitaka Imaizumi, Yumi Takasaki, Jun Nakashima, Takeharu Kato, Hidehiro Itonaga, Shinya Sato, Yasushi Sawayama, Koji Ando, Hiroo Hasegawa, Tomoko Hata, Yukiyoshi Moriuchi, Kunihiro Tsukasaki, Yasushi Miyazaki

ABSTRACT

Watchful waiting (WW) is among the treatment options indicated for patients with indolent adult T-cell leukemia-lymphoma (ATL). However, we previously showed that the long-term prognosis of patients with smoldering and chronic ATL is often worse than expected, with many undergoing transformation to aggressive ATL. To identify clinical features associated with transformation of smoldering/chronic ATL, we retrospectively analyzed the clinical features of 44 patients (14 smoldering and 30 chronic) who experienced transformation during WW. An elevated lactate dehydrogenase (LDH) value was most often observed (n = 30) at the time of transformation, especially in the chronic type (n = 24). Major organ involvement, lymphadenopathy, and hypercalcemia were shown to be associated with transformation in transformed patients without elevated LDH. The median overall survival time after transformation was only 7.8 months, and the prognosis was poor after transformation in those fulfilling the criteria of acute type, similar to that of de novo aggressive ATL. Laboratory data, such as LDH, and clinical signs including exacerbation of performance status, skin lesions, and lymphadenopathy should all be monitored during WW to ensure appropriate timing of chemotherapy initiation. Identification of optimal predictive markers for transformation and new therapeutic options is warranted to improve outcomes in indolent ATL. More... »

PAGES

402-408

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12185-019-02602-4

DOI

http://dx.doi.org/10.1007/s12185-019-02602-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1111636550

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30680667


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Sasebo City General Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415288.2", 
          "name": [
            "Department of Hematology, Sasebo City General Hospital, Sasebo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Taniguchi", 
        "givenName": "Hiroaki", 
        "id": "sg:person.01155434002.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155434002.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411873.8", 
          "name": [
            "Department of Hematology, Nagasaki University Hospital, 1-7-1 Sakamoto, 852-8501, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Imaizumi", 
        "givenName": "Yoshitaka", 
        "id": "sg:person.0700256565.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700256565.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Hematology, Saint Francis Hospital, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takasaki", 
        "givenName": "Yumi", 
        "id": "sg:person.01317362102.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317362102.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411873.8", 
          "name": [
            "Department of Hematology, Nagasaki University Hospital, 1-7-1 Sakamoto, 852-8501, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakashima", 
        "givenName": "Jun", 
        "id": "sg:person.07622752331.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07622752331.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Sasebo City General Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415288.2", 
          "name": [
            "Department of Hematology, Sasebo City General Hospital, Sasebo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kato", 
        "givenName": "Takeharu", 
        "id": "sg:person.0741715421.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741715421.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411873.8", 
          "name": [
            "Department of Hematology, Nagasaki University Hospital, 1-7-1 Sakamoto, 852-8501, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Itonaga", 
        "givenName": "Hidehiro", 
        "id": "sg:person.01221607161.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01221607161.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411873.8", 
          "name": [
            "Department of Hematology, Nagasaki University Hospital, 1-7-1 Sakamoto, 852-8501, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sato", 
        "givenName": "Shinya", 
        "id": "sg:person.01223547202.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223547202.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411873.8", 
          "name": [
            "Department of Hematology, Nagasaki University Hospital, 1-7-1 Sakamoto, 852-8501, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sawayama", 
        "givenName": "Yasushi", 
        "id": "sg:person.01203535355.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01203535355.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411873.8", 
          "name": [
            "Department of Hematology, Nagasaki University Hospital, 1-7-1 Sakamoto, 852-8501, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ando", 
        "givenName": "Koji", 
        "id": "sg:person.0664421234.93", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664421234.93"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411873.8", 
          "name": [
            "Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hasegawa", 
        "givenName": "Hiroo", 
        "id": "sg:person.01236127013.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01236127013.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411873.8", 
          "name": [
            "Department of Hematology, Nagasaki University Hospital, 1-7-1 Sakamoto, 852-8501, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hata", 
        "givenName": "Tomoko", 
        "id": "sg:person.01014505165.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014505165.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Sasebo City General Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415288.2", 
          "name": [
            "Department of Hematology, Sasebo City General Hospital, Sasebo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moriuchi", 
        "givenName": "Yukiyoshi", 
        "id": "sg:person.01227410302.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227410302.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Saitama Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410802.f", 
          "name": [
            "Department of Hematology, International Medical Center, Saitama Medical University, Saitama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tsukasaki", 
        "givenName": "Kunihiro", 
        "id": "sg:person.01356462526.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356462526.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411873.8", 
          "name": [
            "Department of Hematology, Nagasaki University Hospital, 1-7-1 Sakamoto, 852-8501, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miyazaki", 
        "givenName": "Yasushi", 
        "id": "sg:person.016471570462.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016471570462.67"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1046/j.1365-2141.2003.04377.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000323170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/1346-8138.12374", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012010500"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.81.8.2534", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012104740"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood.v97.12.3875", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013699968"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-14-0643", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014718803"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2009-09-242347", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021142891"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2010.28.0669", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033244879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.18.2428", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035918756"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1309/2ygd1p0qcvcwbldx", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036412785"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2015-03-632489", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041002732"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2010-11-316794", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046615543"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2141.1991.tb08051.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048346733"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-14-0572", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049256773"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0145-2126(93)90061-o", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049968984"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081851758", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1997.15.5.1778", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083094754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2017-01-757542", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085470441"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2017-01-761874", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092450109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12185-017-2361-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092459906", 
          "https://doi.org/10.1007/s12185-017-2361-7"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-04", 
    "datePublishedReg": "2019-04-01", 
    "description": "Watchful waiting (WW) is among the treatment options indicated for patients with indolent adult T-cell leukemia-lymphoma (ATL). However, we previously showed that the long-term prognosis of patients with smoldering and chronic ATL is often worse than expected, with many undergoing transformation to aggressive ATL. To identify clinical features associated with transformation of smoldering/chronic ATL, we retrospectively analyzed the clinical features of 44 patients (14 smoldering and 30 chronic) who experienced transformation during WW. An elevated lactate dehydrogenase (LDH) value was most often observed (n\u2009=\u200930) at the time of transformation, especially in the chronic type (n\u2009=\u200924). Major organ involvement, lymphadenopathy, and hypercalcemia were shown to be associated with transformation in transformed patients without elevated LDH. The median overall survival time after transformation was only 7.8 months, and the prognosis was poor after transformation in those fulfilling the criteria of acute type, similar to that of de novo aggressive ATL. Laboratory data, such as LDH, and clinical signs including exacerbation of performance status, skin lesions, and lymphadenopathy should all be monitored during WW to ensure appropriate timing of chemotherapy initiation. Identification of optimal predictive markers for transformation and new therapeutic options is warranted to improve outcomes in indolent ATL.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s12185-019-02602-4", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1076985", 
        "issn": [
          "0925-5710", 
          "1865-3774"
        ], 
        "name": "International Journal of Hematology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "109"
      }
    ], 
    "name": "Clinical features at transformation in adult T-cell leukemia\u2013lymphoma with smoldering and chronic types", 
    "pagination": "402-408", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12185-019-02602-4"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "11f6ef16ce4acc75c1be7e8a87b2874c78b192c006ebb961e6fe149f1beab2f0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1111636550"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9111627"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30680667"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12185-019-02602-4", 
      "https://app.dimensions.ai/details/publication/pub.1111636550"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T09:15", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000376_0000000376/records_56167_00000006.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs12185-019-02602-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12185-019-02602-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12185-019-02602-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12185-019-02602-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12185-019-02602-4'


 

This table displays all metadata directly associated to this object as RDF triples.

226 TRIPLES      21 PREDICATES      48 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12185-019-02602-4 schema:about anzsrc-for:11
2 anzsrc-for:1112
3 schema:author N3ed666aa386e45eeaa962d6cd1edc396
4 schema:citation sg:pub.10.1007/s12185-017-2361-7
5 https://app.dimensions.ai/details/publication/pub.1081851758
6 https://doi.org/10.1016/0145-2126(93)90061-o
7 https://doi.org/10.1046/j.1365-2141.2003.04377.x
8 https://doi.org/10.1073/pnas.81.8.2534
9 https://doi.org/10.1111/1346-8138.12374
10 https://doi.org/10.1111/j.1365-2141.1991.tb08051.x
11 https://doi.org/10.1158/0008-5472.can-14-0643
12 https://doi.org/10.1158/1078-0432.ccr-14-0572
13 https://doi.org/10.1182/blood-2009-09-242347
14 https://doi.org/10.1182/blood-2010-11-316794
15 https://doi.org/10.1182/blood-2015-03-632489
16 https://doi.org/10.1182/blood-2017-01-757542
17 https://doi.org/10.1182/blood-2017-01-761874
18 https://doi.org/10.1182/blood.v97.12.3875
19 https://doi.org/10.1200/jco.1997.15.5.1778
20 https://doi.org/10.1200/jco.2008.18.2428
21 https://doi.org/10.1200/jco.2010.28.0669
22 https://doi.org/10.1309/2ygd1p0qcvcwbldx
23 schema:datePublished 2019-04
24 schema:datePublishedReg 2019-04-01
25 schema:description Watchful waiting (WW) is among the treatment options indicated for patients with indolent adult T-cell leukemia-lymphoma (ATL). However, we previously showed that the long-term prognosis of patients with smoldering and chronic ATL is often worse than expected, with many undergoing transformation to aggressive ATL. To identify clinical features associated with transformation of smoldering/chronic ATL, we retrospectively analyzed the clinical features of 44 patients (14 smoldering and 30 chronic) who experienced transformation during WW. An elevated lactate dehydrogenase (LDH) value was most often observed (n = 30) at the time of transformation, especially in the chronic type (n = 24). Major organ involvement, lymphadenopathy, and hypercalcemia were shown to be associated with transformation in transformed patients without elevated LDH. The median overall survival time after transformation was only 7.8 months, and the prognosis was poor after transformation in those fulfilling the criteria of acute type, similar to that of de novo aggressive ATL. Laboratory data, such as LDH, and clinical signs including exacerbation of performance status, skin lesions, and lymphadenopathy should all be monitored during WW to ensure appropriate timing of chemotherapy initiation. Identification of optimal predictive markers for transformation and new therapeutic options is warranted to improve outcomes in indolent ATL.
26 schema:genre research_article
27 schema:inLanguage en
28 schema:isAccessibleForFree false
29 schema:isPartOf N7c7deed315b449efbb219b7c5418fc95
30 N959e06ff41234d4d83024ecac9d48aa7
31 sg:journal.1076985
32 schema:name Clinical features at transformation in adult T-cell leukemia–lymphoma with smoldering and chronic types
33 schema:pagination 402-408
34 schema:productId N447d59f7c00548f19f0a488793f33fe1
35 Nb11bfaaa3c8d4ee781bce34064821c69
36 Nb80e4d4973474ee688c156da6adac414
37 Nc62ba3bea1a743e29ea19dee99f74b07
38 Ne43b332e07724965913c752dec643e6a
39 schema:sameAs https://app.dimensions.ai/details/publication/pub.1111636550
40 https://doi.org/10.1007/s12185-019-02602-4
41 schema:sdDatePublished 2019-04-15T09:15
42 schema:sdLicense https://scigraph.springernature.com/explorer/license/
43 schema:sdPublisher N8bad07b9e864420e8d89457ddba44d1e
44 schema:url https://link.springer.com/10.1007%2Fs12185-019-02602-4
45 sgo:license sg:explorer/license/
46 sgo:sdDataset articles
47 rdf:type schema:ScholarlyArticle
48 N34e1a3aecfee430b80374a1cab4860ac rdf:first sg:person.01236127013.62
49 rdf:rest N37bb8f07d6714e2999620479cb9c29d2
50 N37bb8f07d6714e2999620479cb9c29d2 rdf:first sg:person.01014505165.38
51 rdf:rest Nf3f0fc20747d4d0eaba7bfad1150021b
52 N3ed666aa386e45eeaa962d6cd1edc396 rdf:first sg:person.01155434002.02
53 rdf:rest N6fe2c51d948245349da4b8cfe46dd108
54 N447d59f7c00548f19f0a488793f33fe1 schema:name nlm_unique_id
55 schema:value 9111627
56 rdf:type schema:PropertyValue
57 N6f00178649144d66a5052786c4ffaed9 rdf:first sg:person.07622752331.36
58 rdf:rest Nce298c22dda34bca86b783eb39938414
59 N6fe2c51d948245349da4b8cfe46dd108 rdf:first sg:person.0700256565.36
60 rdf:rest N84d8c252765f447f9d7ad86cda8cbf59
61 N7c7deed315b449efbb219b7c5418fc95 schema:issueNumber 4
62 rdf:type schema:PublicationIssue
63 N84d8c252765f447f9d7ad86cda8cbf59 rdf:first sg:person.01317362102.52
64 rdf:rest N6f00178649144d66a5052786c4ffaed9
65 N8bad07b9e864420e8d89457ddba44d1e schema:name Springer Nature - SN SciGraph project
66 rdf:type schema:Organization
67 N959e06ff41234d4d83024ecac9d48aa7 schema:volumeNumber 109
68 rdf:type schema:PublicationVolume
69 Na023abbcf90e44d5bd78ef2462018a6c rdf:first sg:person.016471570462.67
70 rdf:rest rdf:nil
71 Na02bcfd02e114e27ab74d662671b210c rdf:first sg:person.01356462526.00
72 rdf:rest Na023abbcf90e44d5bd78ef2462018a6c
73 Na866331696f44f42b0a202f3b9ed86e1 rdf:first sg:person.01203535355.19
74 rdf:rest Nb3fada9d2e81483ba5bb453e644f6198
75 Nad294a2ad31449948905e636c52b3314 schema:name Department of Hematology, Saint Francis Hospital, Nagasaki, Japan
76 rdf:type schema:Organization
77 Nb11bfaaa3c8d4ee781bce34064821c69 schema:name dimensions_id
78 schema:value pub.1111636550
79 rdf:type schema:PropertyValue
80 Nb3fada9d2e81483ba5bb453e644f6198 rdf:first sg:person.0664421234.93
81 rdf:rest N34e1a3aecfee430b80374a1cab4860ac
82 Nb80e4d4973474ee688c156da6adac414 schema:name doi
83 schema:value 10.1007/s12185-019-02602-4
84 rdf:type schema:PropertyValue
85 Nbbbe0817fd914c6c956135a3392e11f3 rdf:first sg:person.01223547202.39
86 rdf:rest Na866331696f44f42b0a202f3b9ed86e1
87 Nc62ba3bea1a743e29ea19dee99f74b07 schema:name pubmed_id
88 schema:value 30680667
89 rdf:type schema:PropertyValue
90 Nce298c22dda34bca86b783eb39938414 rdf:first sg:person.0741715421.34
91 rdf:rest Nd61aaf0f18ad40a2ab8a407b25c6a6f1
92 Nd61aaf0f18ad40a2ab8a407b25c6a6f1 rdf:first sg:person.01221607161.35
93 rdf:rest Nbbbe0817fd914c6c956135a3392e11f3
94 Ne43b332e07724965913c752dec643e6a schema:name readcube_id
95 schema:value 11f6ef16ce4acc75c1be7e8a87b2874c78b192c006ebb961e6fe149f1beab2f0
96 rdf:type schema:PropertyValue
97 Nf3f0fc20747d4d0eaba7bfad1150021b rdf:first sg:person.01227410302.05
98 rdf:rest Na02bcfd02e114e27ab74d662671b210c
99 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
100 schema:name Medical and Health Sciences
101 rdf:type schema:DefinedTerm
102 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
103 schema:name Oncology and Carcinogenesis
104 rdf:type schema:DefinedTerm
105 sg:journal.1076985 schema:issn 0925-5710
106 1865-3774
107 schema:name International Journal of Hematology
108 rdf:type schema:Periodical
109 sg:person.01014505165.38 schema:affiliation https://www.grid.ac/institutes/grid.411873.8
110 schema:familyName Hata
111 schema:givenName Tomoko
112 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014505165.38
113 rdf:type schema:Person
114 sg:person.01155434002.02 schema:affiliation https://www.grid.ac/institutes/grid.415288.2
115 schema:familyName Taniguchi
116 schema:givenName Hiroaki
117 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155434002.02
118 rdf:type schema:Person
119 sg:person.01203535355.19 schema:affiliation https://www.grid.ac/institutes/grid.411873.8
120 schema:familyName Sawayama
121 schema:givenName Yasushi
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01203535355.19
123 rdf:type schema:Person
124 sg:person.01221607161.35 schema:affiliation https://www.grid.ac/institutes/grid.411873.8
125 schema:familyName Itonaga
126 schema:givenName Hidehiro
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01221607161.35
128 rdf:type schema:Person
129 sg:person.01223547202.39 schema:affiliation https://www.grid.ac/institutes/grid.411873.8
130 schema:familyName Sato
131 schema:givenName Shinya
132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223547202.39
133 rdf:type schema:Person
134 sg:person.01227410302.05 schema:affiliation https://www.grid.ac/institutes/grid.415288.2
135 schema:familyName Moriuchi
136 schema:givenName Yukiyoshi
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227410302.05
138 rdf:type schema:Person
139 sg:person.01236127013.62 schema:affiliation https://www.grid.ac/institutes/grid.411873.8
140 schema:familyName Hasegawa
141 schema:givenName Hiroo
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01236127013.62
143 rdf:type schema:Person
144 sg:person.01317362102.52 schema:affiliation Nad294a2ad31449948905e636c52b3314
145 schema:familyName Takasaki
146 schema:givenName Yumi
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317362102.52
148 rdf:type schema:Person
149 sg:person.01356462526.00 schema:affiliation https://www.grid.ac/institutes/grid.410802.f
150 schema:familyName Tsukasaki
151 schema:givenName Kunihiro
152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01356462526.00
153 rdf:type schema:Person
154 sg:person.016471570462.67 schema:affiliation https://www.grid.ac/institutes/grid.411873.8
155 schema:familyName Miyazaki
156 schema:givenName Yasushi
157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016471570462.67
158 rdf:type schema:Person
159 sg:person.0664421234.93 schema:affiliation https://www.grid.ac/institutes/grid.411873.8
160 schema:familyName Ando
161 schema:givenName Koji
162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0664421234.93
163 rdf:type schema:Person
164 sg:person.0700256565.36 schema:affiliation https://www.grid.ac/institutes/grid.411873.8
165 schema:familyName Imaizumi
166 schema:givenName Yoshitaka
167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700256565.36
168 rdf:type schema:Person
169 sg:person.0741715421.34 schema:affiliation https://www.grid.ac/institutes/grid.415288.2
170 schema:familyName Kato
171 schema:givenName Takeharu
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741715421.34
173 rdf:type schema:Person
174 sg:person.07622752331.36 schema:affiliation https://www.grid.ac/institutes/grid.411873.8
175 schema:familyName Nakashima
176 schema:givenName Jun
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07622752331.36
178 rdf:type schema:Person
179 sg:pub.10.1007/s12185-017-2361-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092459906
180 https://doi.org/10.1007/s12185-017-2361-7
181 rdf:type schema:CreativeWork
182 https://app.dimensions.ai/details/publication/pub.1081851758 schema:CreativeWork
183 https://doi.org/10.1016/0145-2126(93)90061-o schema:sameAs https://app.dimensions.ai/details/publication/pub.1049968984
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1046/j.1365-2141.2003.04377.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1000323170
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1073/pnas.81.8.2534 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012104740
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1111/1346-8138.12374 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012010500
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1111/j.1365-2141.1991.tb08051.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048346733
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1158/0008-5472.can-14-0643 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014718803
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1158/1078-0432.ccr-14-0572 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049256773
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1182/blood-2009-09-242347 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021142891
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1182/blood-2010-11-316794 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046615543
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1182/blood-2015-03-632489 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041002732
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1182/blood-2017-01-757542 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085470441
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1182/blood-2017-01-761874 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092450109
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1182/blood.v97.12.3875 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013699968
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1200/jco.1997.15.5.1778 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083094754
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1200/jco.2008.18.2428 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035918756
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1200/jco.2010.28.0669 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033244879
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1309/2ygd1p0qcvcwbldx schema:sameAs https://app.dimensions.ai/details/publication/pub.1036412785
216 rdf:type schema:CreativeWork
217 https://www.grid.ac/institutes/grid.410802.f schema:alternateName Saitama Medical University
218 schema:name Department of Hematology, International Medical Center, Saitama Medical University, Saitama, Japan
219 rdf:type schema:Organization
220 https://www.grid.ac/institutes/grid.411873.8 schema:alternateName Nagasaki University Hospital
221 schema:name Department of Hematology, Nagasaki University Hospital, 1-7-1 Sakamoto, 852-8501, Nagasaki, Japan
222 Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan
223 rdf:type schema:Organization
224 https://www.grid.ac/institutes/grid.415288.2 schema:alternateName Sasebo City General Hospital
225 schema:name Department of Hematology, Sasebo City General Hospital, Sasebo, Japan
226 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...