Three cases of relapsed/refractory multiple myeloma under hemodialysis treated with panobinostat/bortezomib/dexamethasone (FVD) View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-10

AUTHORS

Yasunobu Sekiguchi, Haruko Takizawa, Tadaaki Inano, Yasutaka Fukuda, Mutsumi Wakabayashi, Keiji Sugimoto, Shigeki Tomita, Hiroshi Izumi, Noriko Nakamura, Tomohiro Sawada, Yasunori Ohta, Norio Komatsu, Masaaki Noguchi

ABSTRACT

Three patients under hemodialysis (HD) with relapsed/refractory multiple myeloma (MM) were administered panobinostat/bortezomib/dexamethasone (FVD). Case 1: The patient was a 66-year-old male with BJP-κ. FVD was effective, but HD could not be discontinued. He developed Grade 3 adverse events (AEs), including nausea, dehydration, and fatigue, following the common terminology criteria for adverse events v4.0. FVD was discontinued after the third course, while HD was continued. Case 2: The patient was a 65-year-old female with IgG-λ + BJP-λ. Amyloidosis was complicated. The first course of FVD was effective, but HD could not be discontinued. She developed G2 AEs, including nausea and fatigue. The cardiac amyloidosis worsened, and she died of heart and renal failure. Case 3: The patient was a 79-year-old male with BJP-κ. FVD was effective, and the HD could be discontinued on day 12 of treatment. No AEs were noted. However, he declined continuation of the FVD and died of MM relapse and renal failure. We analyzed the pharmacokinetics of panobinostat. There were no correlations between dose level and blood level of panobinostat or between blood level, efficacy, and incidence of AEs. We additionally measured the rate of elimination of the drug by HD. More... »

PAGES

581-587

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12185-017-2222-4

DOI

http://dx.doi.org/10.1007/s12185-017-2222-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1084034361

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/28353192


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antineoplastic Combined Chemotherapy Protocols", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bortezomib", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dexamethasone", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydroxamic Acids", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Indoles", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Multiple Myeloma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Panobinostat", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recurrence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Renal Dialysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Renal Insufficiency", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Juntendo University Urayasu Hospital", 
          "id": "https://www.grid.ac/institutes/grid.482669.7", 
          "name": [
            "Department of Hematology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sekiguchi", 
        "givenName": "Yasunobu", 
        "id": "sg:person.01071674054.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071674054.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Juntendo University Urayasu Hospital", 
          "id": "https://www.grid.ac/institutes/grid.482669.7", 
          "name": [
            "Department of Hematology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takizawa", 
        "givenName": "Haruko", 
        "id": "sg:person.013632136043.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013632136043.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Juntendo University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411966.d", 
          "name": [
            "Department of Hematology, Juntendo University Hospital, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Inano", 
        "givenName": "Tadaaki", 
        "id": "sg:person.014427516443.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014427516443.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Juntendo University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411966.d", 
          "name": [
            "Department of Hematology, Juntendo University Hospital, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fukuda", 
        "givenName": "Yasutaka", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Juntendo University Urayasu Hospital", 
          "id": "https://www.grid.ac/institutes/grid.482669.7", 
          "name": [
            "Department of Hematology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wakabayashi", 
        "givenName": "Mutsumi", 
        "id": "sg:person.01133415712.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133415712.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Juntendo University Urayasu Hospital", 
          "id": "https://www.grid.ac/institutes/grid.482669.7", 
          "name": [
            "Department of Hematology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sugimoto", 
        "givenName": "Keiji", 
        "id": "sg:person.0745322755.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745322755.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Juntendo University Urayasu Hospital", 
          "id": "https://www.grid.ac/institutes/grid.482669.7", 
          "name": [
            "Department of Pathology, Juntendo University Urayasu Hospital, Urayasu, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tomita", 
        "givenName": "Shigeki", 
        "id": "sg:person.01232501437.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01232501437.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Juntendo University Urayasu Hospital", 
          "id": "https://www.grid.ac/institutes/grid.482669.7", 
          "name": [
            "Department of Pathology, Juntendo University Urayasu Hospital, Urayasu, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Izumi", 
        "givenName": "Hiroshi", 
        "id": "sg:person.01331666326.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331666326.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Juntendo University Urayasu Hospital", 
          "id": "https://www.grid.ac/institutes/grid.482669.7", 
          "name": [
            "Department of Clinical Laboratory, Juntendo University Urayasu Hospital, Urayasu, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakamura", 
        "givenName": "Noriko", 
        "id": "sg:person.0754751265.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754751265.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Juntendo University Urayasu Hospital", 
          "id": "https://www.grid.ac/institutes/grid.482669.7", 
          "name": [
            "Department of Clinical Laboratory, Juntendo University Urayasu Hospital, Urayasu, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sawada", 
        "givenName": "Tomohiro", 
        "id": "sg:person.01364072712.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01364072712.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Pathology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ohta", 
        "givenName": "Yasunori", 
        "id": "sg:person.01051200156.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051200156.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Juntendo University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.411966.d", 
          "name": [
            "Department of Hematology, Juntendo University Hospital, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Komatsu", 
        "givenName": "Norio", 
        "id": "sg:person.0763374015.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763374015.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Juntendo University Urayasu Hospital", 
          "id": "https://www.grid.ac/institutes/grid.482669.7", 
          "name": [
            "Department of Hematology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Noguchi", 
        "givenName": "Masaaki", 
        "id": "sg:person.01137257012.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137257012.68"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1182/blood-2013-01-481325", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007945178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(14)70440-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021265625"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/leu.2011.196", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031416563", 
          "https://doi.org/10.1038/leu.2011.196"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00280-014-2612-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032975415", 
          "https://doi.org/10.1007/s00280-014-2612-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2012.46.7068", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050901978"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-10", 
    "datePublishedReg": "2017-10-01", 
    "description": "Three patients under hemodialysis (HD) with relapsed/refractory multiple myeloma (MM) were administered panobinostat/bortezomib/dexamethasone (FVD). Case 1: The patient was a 66-year-old male with BJP-\u03ba. FVD was effective, but HD could not be discontinued. He developed Grade 3 adverse events (AEs), including nausea, dehydration, and fatigue, following the common terminology criteria for adverse events v4.0. FVD was discontinued after the third course, while HD was continued. Case 2: The patient was a 65-year-old female with IgG-\u03bb\u00a0+\u00a0BJP-\u03bb. Amyloidosis was complicated. The first course of FVD was effective, but HD could not be discontinued. She developed G2 AEs, including nausea and fatigue. The cardiac amyloidosis worsened, and she died of heart and renal failure. Case 3: The patient was a 79-year-old male with BJP-\u03ba. FVD was effective, and the HD could be discontinued on day 12 of treatment. No AEs were noted. However, he declined continuation of the FVD and died of MM relapse and renal failure. We analyzed the pharmacokinetics of panobinostat. There were no correlations between dose level and blood level of panobinostat or between blood level, efficacy, and incidence of AEs. We additionally measured the rate of elimination of the drug by HD.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s12185-017-2222-4", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1076985", 
        "issn": [
          "0925-5710", 
          "1865-3774"
        ], 
        "name": "International Journal of Hematology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "106"
      }
    ], 
    "name": "Three cases of relapsed/refractory multiple myeloma under hemodialysis treated with panobinostat/bortezomib/dexamethasone (FVD)", 
    "pagination": "581-587", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "2f67392af9afef810ccfe699d7e47e2cc1760a29a62c3b52238fab9553061700"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "28353192"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9111627"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12185-017-2222-4"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1084034361"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12185-017-2222-4", 
      "https://app.dimensions.ai/details/publication/pub.1084034361"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T09:51", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89789_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs12185-017-2222-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12185-017-2222-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12185-017-2222-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12185-017-2222-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12185-017-2222-4'


 

This table displays all metadata directly associated to this object as RDF triples.

233 TRIPLES      21 PREDICATES      48 URIs      35 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12185-017-2222-4 schema:about N181fc2eac15a4fc9a906d912b7bd7431
2 N455caa1bfc6f47c08ea5d32ebc8af668
3 N47d8758baf71441c8dc741ed6587713b
4 N50ea145dfc1e4983b63ca45dee2c091c
5 N511eaccc5cad44dbaac12b4a0b6a10dc
6 N5e2e6f342f8a4db19a247af9a5e0e6b9
7 N7042129cc4d543b88e2d5c45f526990a
8 N85679b7016814d39881e11c68e1cb58a
9 N9c0a462c271649f89a6343fbfadbc2e6
10 Nbd12f9f6a520464dbc7541de7d93fc3d
11 Nc4033978bf964be99695507b78d63539
12 Ncef479a403324d7096370f212d73fbbf
13 Ne2f11d3c64104ee492f5840fbbc6b56c
14 Neb38b2c5a04e4202982f65df280a1fba
15 anzsrc-for:11
16 anzsrc-for:1102
17 schema:author Ndca298a4788c4bdd92af46c2283440a8
18 schema:citation sg:pub.10.1007/s00280-014-2612-8
19 sg:pub.10.1038/leu.2011.196
20 https://doi.org/10.1016/s1470-2045(14)70440-1
21 https://doi.org/10.1182/blood-2013-01-481325
22 https://doi.org/10.1200/jco.2012.46.7068
23 schema:datePublished 2017-10
24 schema:datePublishedReg 2017-10-01
25 schema:description Three patients under hemodialysis (HD) with relapsed/refractory multiple myeloma (MM) were administered panobinostat/bortezomib/dexamethasone (FVD). Case 1: The patient was a 66-year-old male with BJP-κ. FVD was effective, but HD could not be discontinued. He developed Grade 3 adverse events (AEs), including nausea, dehydration, and fatigue, following the common terminology criteria for adverse events v4.0. FVD was discontinued after the third course, while HD was continued. Case 2: The patient was a 65-year-old female with IgG-λ + BJP-λ. Amyloidosis was complicated. The first course of FVD was effective, but HD could not be discontinued. She developed G2 AEs, including nausea and fatigue. The cardiac amyloidosis worsened, and she died of heart and renal failure. Case 3: The patient was a 79-year-old male with BJP-κ. FVD was effective, and the HD could be discontinued on day 12 of treatment. No AEs were noted. However, he declined continuation of the FVD and died of MM relapse and renal failure. We analyzed the pharmacokinetics of panobinostat. There were no correlations between dose level and blood level of panobinostat or between blood level, efficacy, and incidence of AEs. We additionally measured the rate of elimination of the drug by HD.
26 schema:genre research_article
27 schema:inLanguage en
28 schema:isAccessibleForFree false
29 schema:isPartOf N399f6eb9b09a499cb86c7509340ed01a
30 N941f8f2f25e5420e97b0680705811349
31 sg:journal.1076985
32 schema:name Three cases of relapsed/refractory multiple myeloma under hemodialysis treated with panobinostat/bortezomib/dexamethasone (FVD)
33 schema:pagination 581-587
34 schema:productId N238e7a4dbdab467fbc961e9197f78094
35 N7585e55a9b01487e84b8e1fd7bc4c9b2
36 N7ac39a73e2f74a299cb94c607976d248
37 N893b7b299d414af29b90217e64bf8778
38 Nc05d8e8a138f49128df922c2fdedc6f6
39 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084034361
40 https://doi.org/10.1007/s12185-017-2222-4
41 schema:sdDatePublished 2019-04-11T09:51
42 schema:sdLicense https://scigraph.springernature.com/explorer/license/
43 schema:sdPublisher Nb98d43f6b8124754af3bc22d83c18c27
44 schema:url https://link.springer.com/10.1007%2Fs12185-017-2222-4
45 sgo:license sg:explorer/license/
46 sgo:sdDataset articles
47 rdf:type schema:ScholarlyArticle
48 N0314ab8db5ab452fbe9ce70b5c8e0572 rdf:first sg:person.01331666326.86
49 rdf:rest Nc39201a24b4547a3a740f9371952071f
50 N03effba7452647fb86318b1a90a7ccd7 rdf:first sg:person.0745322755.14
51 rdf:rest Nfac60b2d5c3b4b59bb750e8d49ab9f6f
52 N0703f7a53a234bc58561ace4634d2e62 rdf:first sg:person.01051200156.37
53 rdf:rest Nac4f1d154b6540d991881c45be1b004e
54 N181fc2eac15a4fc9a906d912b7bd7431 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
55 schema:name Humans
56 rdf:type schema:DefinedTerm
57 N1888600b0fe44c16b7dffbecbe24bc79 schema:affiliation https://www.grid.ac/institutes/grid.411966.d
58 schema:familyName Fukuda
59 schema:givenName Yasutaka
60 rdf:type schema:Person
61 N238e7a4dbdab467fbc961e9197f78094 schema:name doi
62 schema:value 10.1007/s12185-017-2222-4
63 rdf:type schema:PropertyValue
64 N2538189a5dcf4c6c85ddb00900a68c44 rdf:first sg:person.01364072712.46
65 rdf:rest N0703f7a53a234bc58561ace4634d2e62
66 N399f6eb9b09a499cb86c7509340ed01a schema:volumeNumber 106
67 rdf:type schema:PublicationVolume
68 N455caa1bfc6f47c08ea5d32ebc8af668 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
69 schema:name Bortezomib
70 rdf:type schema:DefinedTerm
71 N47d8758baf71441c8dc741ed6587713b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
72 schema:name Renal Insufficiency
73 rdf:type schema:DefinedTerm
74 N49e2bd3372fb4044ae53149008abad19 rdf:first sg:person.013632136043.01
75 rdf:rest N605301da1f4e40af853ef8d3146ca058
76 N50ea145dfc1e4983b63ca45dee2c091c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name Renal Dialysis
78 rdf:type schema:DefinedTerm
79 N511eaccc5cad44dbaac12b4a0b6a10dc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Aged
81 rdf:type schema:DefinedTerm
82 N5946e4f43e3b48e19536776ec59af6d0 rdf:first sg:person.01133415712.47
83 rdf:rest N03effba7452647fb86318b1a90a7ccd7
84 N5e2e6f342f8a4db19a247af9a5e0e6b9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Dexamethasone
86 rdf:type schema:DefinedTerm
87 N605301da1f4e40af853ef8d3146ca058 rdf:first sg:person.014427516443.42
88 rdf:rest N79701895a04c48c5a8c88b143bb95f21
89 N7042129cc4d543b88e2d5c45f526990a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Multiple Myeloma
91 rdf:type schema:DefinedTerm
92 N7585e55a9b01487e84b8e1fd7bc4c9b2 schema:name nlm_unique_id
93 schema:value 9111627
94 rdf:type schema:PropertyValue
95 N79701895a04c48c5a8c88b143bb95f21 rdf:first N1888600b0fe44c16b7dffbecbe24bc79
96 rdf:rest N5946e4f43e3b48e19536776ec59af6d0
97 N7ac39a73e2f74a299cb94c607976d248 schema:name dimensions_id
98 schema:value pub.1084034361
99 rdf:type schema:PropertyValue
100 N85679b7016814d39881e11c68e1cb58a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Indoles
102 rdf:type schema:DefinedTerm
103 N893b7b299d414af29b90217e64bf8778 schema:name readcube_id
104 schema:value 2f67392af9afef810ccfe699d7e47e2cc1760a29a62c3b52238fab9553061700
105 rdf:type schema:PropertyValue
106 N941f8f2f25e5420e97b0680705811349 schema:issueNumber 4
107 rdf:type schema:PublicationIssue
108 N9c0a462c271649f89a6343fbfadbc2e6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Antineoplastic Combined Chemotherapy Protocols
110 rdf:type schema:DefinedTerm
111 N9efc9589d35242b4801877a45e4a3c30 rdf:first sg:person.01137257012.68
112 rdf:rest rdf:nil
113 Nac4f1d154b6540d991881c45be1b004e rdf:first sg:person.0763374015.04
114 rdf:rest N9efc9589d35242b4801877a45e4a3c30
115 Nb98d43f6b8124754af3bc22d83c18c27 schema:name Springer Nature - SN SciGraph project
116 rdf:type schema:Organization
117 Nbd12f9f6a520464dbc7541de7d93fc3d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Female
119 rdf:type schema:DefinedTerm
120 Nc05d8e8a138f49128df922c2fdedc6f6 schema:name pubmed_id
121 schema:value 28353192
122 rdf:type schema:PropertyValue
123 Nc39201a24b4547a3a740f9371952071f rdf:first sg:person.0754751265.48
124 rdf:rest N2538189a5dcf4c6c85ddb00900a68c44
125 Nc4033978bf964be99695507b78d63539 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Panobinostat
127 rdf:type schema:DefinedTerm
128 Ncef479a403324d7096370f212d73fbbf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Male
130 rdf:type schema:DefinedTerm
131 Ndca298a4788c4bdd92af46c2283440a8 rdf:first sg:person.01071674054.05
132 rdf:rest N49e2bd3372fb4044ae53149008abad19
133 Ne2f11d3c64104ee492f5840fbbc6b56c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Hydroxamic Acids
135 rdf:type schema:DefinedTerm
136 Neb38b2c5a04e4202982f65df280a1fba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Recurrence
138 rdf:type schema:DefinedTerm
139 Nfac60b2d5c3b4b59bb750e8d49ab9f6f rdf:first sg:person.01232501437.66
140 rdf:rest N0314ab8db5ab452fbe9ce70b5c8e0572
141 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
142 schema:name Medical and Health Sciences
143 rdf:type schema:DefinedTerm
144 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
145 schema:name Cardiorespiratory Medicine and Haematology
146 rdf:type schema:DefinedTerm
147 sg:journal.1076985 schema:issn 0925-5710
148 1865-3774
149 schema:name International Journal of Hematology
150 rdf:type schema:Periodical
151 sg:person.01051200156.37 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
152 schema:familyName Ohta
153 schema:givenName Yasunori
154 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051200156.37
155 rdf:type schema:Person
156 sg:person.01071674054.05 schema:affiliation https://www.grid.ac/institutes/grid.482669.7
157 schema:familyName Sekiguchi
158 schema:givenName Yasunobu
159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071674054.05
160 rdf:type schema:Person
161 sg:person.01133415712.47 schema:affiliation https://www.grid.ac/institutes/grid.482669.7
162 schema:familyName Wakabayashi
163 schema:givenName Mutsumi
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133415712.47
165 rdf:type schema:Person
166 sg:person.01137257012.68 schema:affiliation https://www.grid.ac/institutes/grid.482669.7
167 schema:familyName Noguchi
168 schema:givenName Masaaki
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01137257012.68
170 rdf:type schema:Person
171 sg:person.01232501437.66 schema:affiliation https://www.grid.ac/institutes/grid.482669.7
172 schema:familyName Tomita
173 schema:givenName Shigeki
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01232501437.66
175 rdf:type schema:Person
176 sg:person.01331666326.86 schema:affiliation https://www.grid.ac/institutes/grid.482669.7
177 schema:familyName Izumi
178 schema:givenName Hiroshi
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331666326.86
180 rdf:type schema:Person
181 sg:person.013632136043.01 schema:affiliation https://www.grid.ac/institutes/grid.482669.7
182 schema:familyName Takizawa
183 schema:givenName Haruko
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013632136043.01
185 rdf:type schema:Person
186 sg:person.01364072712.46 schema:affiliation https://www.grid.ac/institutes/grid.482669.7
187 schema:familyName Sawada
188 schema:givenName Tomohiro
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01364072712.46
190 rdf:type schema:Person
191 sg:person.014427516443.42 schema:affiliation https://www.grid.ac/institutes/grid.411966.d
192 schema:familyName Inano
193 schema:givenName Tadaaki
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014427516443.42
195 rdf:type schema:Person
196 sg:person.0745322755.14 schema:affiliation https://www.grid.ac/institutes/grid.482669.7
197 schema:familyName Sugimoto
198 schema:givenName Keiji
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745322755.14
200 rdf:type schema:Person
201 sg:person.0754751265.48 schema:affiliation https://www.grid.ac/institutes/grid.482669.7
202 schema:familyName Nakamura
203 schema:givenName Noriko
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0754751265.48
205 rdf:type schema:Person
206 sg:person.0763374015.04 schema:affiliation https://www.grid.ac/institutes/grid.411966.d
207 schema:familyName Komatsu
208 schema:givenName Norio
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763374015.04
210 rdf:type schema:Person
211 sg:pub.10.1007/s00280-014-2612-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032975415
212 https://doi.org/10.1007/s00280-014-2612-8
213 rdf:type schema:CreativeWork
214 sg:pub.10.1038/leu.2011.196 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031416563
215 https://doi.org/10.1038/leu.2011.196
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1016/s1470-2045(14)70440-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021265625
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1182/blood-2013-01-481325 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007945178
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1200/jco.2012.46.7068 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050901978
222 rdf:type schema:CreativeWork
223 https://www.grid.ac/institutes/grid.26999.3d schema:alternateName University of Tokyo
224 schema:name Department of Pathology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
225 rdf:type schema:Organization
226 https://www.grid.ac/institutes/grid.411966.d schema:alternateName Juntendo University Hospital
227 schema:name Department of Hematology, Juntendo University Hospital, Tokyo, Japan
228 rdf:type schema:Organization
229 https://www.grid.ac/institutes/grid.482669.7 schema:alternateName Juntendo University Urayasu Hospital
230 schema:name Department of Clinical Laboratory, Juntendo University Urayasu Hospital, Urayasu, Japan
231 Department of Hematology, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, Japan
232 Department of Pathology, Juntendo University Urayasu Hospital, Urayasu, Japan
233 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...