Phase 2 trial of daily, oral epigallocatechin gallate in patients with light-chain amyloidosis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-03

AUTHORS

Sohsuke Meshitsuka, Sumito Shingaki, Masatoshi Hotta, Miku Goto, Makoto Kobayashi, Yuuichi Ukawa, Yuko M. Sagesaka, Yasuyo Wada, Masanori Nojima, Kenshi Suzuki

ABSTRACT

Previous studies have suggested that an increase in mitochondrial reactive oxygen species may cause organ damage in patients with light-chain (AL) amyloidosis; however, this damage can be decreased by antioxidant-agent treatment. Epigallocatechin gallate (EGCG), the major natural catechin in green tea, has potent antioxidant activity. Because EGCG has recently been reported to have a favorable toxicity profile for treating amyloidosis, we sought to examine the clinical efficacy and toxicity of EGCG in patients with AL amyloidosis. Fifty-seven patients were randomly assigned to the EGCG and observation groups and observed for six months. There were no increases in grade 3-5 adverse events and EGCG therapy was well tolerated. Although a decrease in the urinary albumin level was found in the EGCG group in patients with obvious albuminuria after treatment initiation, its antioxidant activity may not be sufficient to clarify the potential effect of EGCG in patients with AL amyloidosis. Because some of the biological markers responsible for organ damage were well correlated to the level of antioxidant potential in patients' plasma, the status of oxidative stress in the blood may indicate the extent of organ damage in clinical situations. More... »

PAGES

295-308

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12185-016-2112-1

DOI

http://dx.doi.org/10.1007/s12185-016-2112-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1035478151

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27815860


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amyloidosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antioxidants", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Catechin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunoglobulin Light-chain Amyloidosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oxidative Stress", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reactive Oxygen Species", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tea", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan", 
            "Center for Translational Research, The Institute of Medical Science Hospital, The University of Tokyo, 4-6-1, Shiroganedai, Minato, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Meshitsuka", 
        "givenName": "Sohsuke", 
        "id": "sg:person.01305523257.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305523257.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Japanese Red Cross Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.414929.3", 
          "name": [
            "Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shingaki", 
        "givenName": "Sumito", 
        "id": "sg:person.01023004677.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023004677.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Center For Global Health and Medicine", 
          "id": "https://www.grid.ac/institutes/grid.45203.30", 
          "name": [
            "Department of Radiology, National Center for Global Health and Medicine, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hotta", 
        "givenName": "Masatoshi", 
        "id": "sg:person.07643060755.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07643060755.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Jumonji University", 
          "id": "https://www.grid.ac/institutes/grid.444497.e", 
          "name": [
            "Laboratory for Clinical Nutrition, Department of Food and Nutrition, Faculty of Human Life, Jumonji University, Niiza, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Goto", 
        "givenName": "Miku", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Central Research Institute, ITO EN, Ltd, Makinohara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kobayashi", 
        "givenName": "Makoto", 
        "id": "sg:person.01022514742.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022514742.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Central Research Institute, ITO EN, Ltd, Makinohara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ukawa", 
        "givenName": "Yuuichi", 
        "id": "sg:person.01330073613.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330073613.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Central Research Institute, ITO EN, Ltd, Makinohara, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sagesaka", 
        "givenName": "Yuko M.", 
        "id": "sg:person.01206437067.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01206437067.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Jumonji University", 
          "id": "https://www.grid.ac/institutes/grid.444497.e", 
          "name": [
            "Laboratory for Clinical Nutrition, Department of Food and Nutrition, Faculty of Human Life, Jumonji University, Niiza, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wada", 
        "givenName": "Yasuyo", 
        "id": "sg:person.01125477724.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125477724.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Center for Translational Research, The Institute of Medical Science Hospital, The University of Tokyo, 4-6-1, Shiroganedai, Minato, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nojima", 
        "givenName": "Masanori", 
        "id": "sg:person.0730703067.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730703067.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Japanese Red Cross Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.414929.3", 
          "name": [
            "Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Suzuki", 
        "givenName": "Kenshi", 
        "id": "sg:person.014724732234.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014724732234.38"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/bmt.2012.170", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000671960", 
          "https://doi.org/10.1038/bmt.2012.170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-04-2549", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001008566"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0735-1097(90)90183-p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001123098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2012-02-413161", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001203356"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2010.32.2271", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001608170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2011.37.7614", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002191429"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajh.20381", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002848933"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajh.20381", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002848933"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/hrt.2009.190405", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003622544"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2012.02.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004054282"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2015.63.6530", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004331863"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb.1437", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005415073", 
          "https://doi.org/10.1038/nsmb.1437"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00392-008-0649-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007455323", 
          "https://doi.org/10.1007/s00392-008-0649-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00392-008-0649-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007455323", 
          "https://doi.org/10.1007/s00392-008-0649-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.00815.2011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008071002"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00395-013-0378-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008971897", 
          "https://doi.org/10.1007/s00395-013-0378-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00277-011-1244-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010504326", 
          "https://doi.org/10.1007/s00277-011-1244-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2353/ajpath.2006.060183", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011304877"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4142/jvs.2007.8.2.121", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011935584"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4142/jvs.2007.8.2.121", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011935584"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2014-04-570010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012674514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2014-04-570010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012674514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00392-010-0142-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013784425", 
          "https://doi.org/10.1007/s00392-010-0142-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00392-010-0142-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013784425", 
          "https://doi.org/10.1007/s00392-010-0142-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0268-960x(03)00027-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015241684"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0268-960x(03)00027-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015241684"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jnutbio.2005.03.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015779657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jnutbio.2005.03.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015779657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2011-04-351643", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016533109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2011-04-351643", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016533109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/qjmed/91.2.141", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017665623"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm400161p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018459361"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mito.2009.11.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019537189"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.63.1.188", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019630398"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2013-10-525634", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019794653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-6143.2010.03227.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021165951"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-6143.2010.03227.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021165951"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2004.03.029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021510596"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-6143.2009.02643.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022454495"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-6143.2009.02643.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022454495"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.hoc.2014.08.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023127744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.hoc.2014.08.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023127744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.104.489187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023531372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/10428194.2010.524329", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023881545"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circimaging.112.978627", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024381419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circimaging.112.978627", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024381419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circimaging.112.978627", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024381419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.27719", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024667466"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000320201", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025033045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1271/bbb.90195", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025358232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1271/bbb.90195", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025358232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pro.2730", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025901868"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pro.2730", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025901868"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2007-05-089243", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027025880"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2009-07-230722", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027383713"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.foodchem.2010.04.048", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028080156"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.str.2010.02.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028098222"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3999/jscpt.43.9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028165366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2006-07-035352", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031509094"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa070484", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031535131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2006-05-022814", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032212284"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2011.38.5724", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034788718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1163/156856700x00769", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035074621", 
          "https://doi.org/10.1163/156856700x00769"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/13506129.2015.1113167", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035326945"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/13506129.2012.733741", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035490701"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.00186.2013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037254834"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2011-01-330738", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037479683"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3324/haematol.2013.095463", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039671781"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3324/haematol.2013.095463", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039671781"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0735-1097(90)90545-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039690433"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.21.1284", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040014032"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bmt.1704691", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040030206", 
          "https://doi.org/10.1038/sj.bmt.1704691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.0000068313.67758.4f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040255511"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.73.2.249", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040806401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehu444", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040905674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0910723107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041032441"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2014-04-568329", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041595513"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2014-04-568329", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041595513"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.1521-05.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041769968"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjcard.2007.11.047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042031424"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmra023144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044393230"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2005-11-4385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044573091"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0912263107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047827748"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.res.0000126569.75419.74", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049323053"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.res.0000126569.75419.74", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049323053"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2011-05-355784", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049758352"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0137716", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050593489"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1504942", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051001137"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1504942", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051001137"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.15252/emmm.201404190", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051596813"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11033-016-4022-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051925206", 
          "https://doi.org/10.1007/s11033-016-4022-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11033-016-4022-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051925206", 
          "https://doi.org/10.1007/s11033-016-4022-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/tp.0b013e3181f10edb", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052194145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/tp.0b013e3181f10edb", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052194145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/tp.0b013e3181f10edb", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052194145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcmg.2012.11.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052202417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi1004409", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055203165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi1004409", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055203165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jf0522199", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055904392"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jf0522199", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055904392"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m116.736736", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058215156"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/1568026611212220007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069194518"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074498098", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circ.104.14.1594", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074888066"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jn/131.12.3208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074962597"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2017-03", 
    "datePublishedReg": "2017-03-01", 
    "description": "Previous studies have suggested that an increase in mitochondrial reactive oxygen species may cause organ damage in patients with light-chain (AL) amyloidosis; however, this damage can be decreased by antioxidant-agent treatment. Epigallocatechin gallate (EGCG), the major natural catechin in green tea, has potent antioxidant activity. Because EGCG has recently been reported to have a favorable toxicity profile for treating amyloidosis, we sought to examine the clinical efficacy and toxicity of EGCG in patients with AL amyloidosis. Fifty-seven patients were randomly assigned to the EGCG and observation groups and observed for six months. There were no increases in grade 3-5 adverse events and EGCG therapy was well tolerated. Although a decrease in the urinary albumin level was found in the EGCG group in patients with obvious albuminuria after treatment initiation, its antioxidant activity may not be sufficient to clarify the potential effect of EGCG in patients with AL amyloidosis. Because some of the biological markers responsible for organ damage were well correlated to the level of antioxidant potential in patients' plasma, the status of oxidative stress in the blood may indicate the extent of organ damage in clinical situations.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s12185-016-2112-1", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1076985", 
        "issn": [
          "0925-5710", 
          "1865-3774"
        ], 
        "name": "International Journal of Hematology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "105"
      }
    ], 
    "name": "Phase 2 trial of daily, oral epigallocatechin gallate in patients with light-chain amyloidosis", 
    "pagination": "295-308", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "a900bcec4ecb90463df2f09fe060d3bf6851980329f2643e8e310ab1957c9021"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27815860"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9111627"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12185-016-2112-1"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1035478151"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12185-016-2112-1", 
      "https://app.dimensions.ai/details/publication/pub.1035478151"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:39", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000363_0000000363/records_70043_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs12185-016-2112-1"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12185-016-2112-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12185-016-2112-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12185-016-2112-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12185-016-2112-1'


 

This table displays all metadata directly associated to this object as RDF triples.

458 TRIPLES      21 PREDICATES      125 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12185-016-2112-1 schema:about N0c94cf4ae91f4e43bf71622d7a2f045f
2 N13d43c40674e4d54af76b1ead36322a1
3 N22719064450643568ebb20d280e21ed6
4 N2fb1b15cdfcf41a788977cef686a1289
5 N3551d93e4f34495d9eda950f9ad4e4ca
6 N39f56b8484774443b778ff96d7c4684a
7 N3b0cccac620b49fc8a01fbe8d4d065dd
8 N56de0a07952041f4accbcb04bde438fa
9 N60018edec730448fb654de9803962b68
10 N87b0c2f8843d4227b7e2a67e619c6b5f
11 Nbf143b3f3f514bbca09819f7c9a07631
12 Nc3ccb9b1025449bd8cf6d9b1de82ebca
13 Nca34b2c53fbd4706b252176c17f2100c
14 Nd31888c9cad541a1be623392d5981fb1
15 Nfeb18761fc4c461e890cc75d47f3964f
16 anzsrc-for:11
17 anzsrc-for:1103
18 schema:author N3590a4d726df4b2bb914390242a811c0
19 schema:citation sg:pub.10.1007/s00277-011-1244-x
20 sg:pub.10.1007/s00392-008-0649-6
21 sg:pub.10.1007/s00392-010-0142-x
22 sg:pub.10.1007/s00395-013-0378-5
23 sg:pub.10.1007/s11033-016-4022-y
24 sg:pub.10.1038/bmt.2012.170
25 sg:pub.10.1038/nsmb.1437
26 sg:pub.10.1038/sj.bmt.1704691
27 sg:pub.10.1163/156856700x00769
28 https://app.dimensions.ai/details/publication/pub.1074498098
29 https://doi.org/10.1002/ajh.20381
30 https://doi.org/10.1002/cncr.27719
31 https://doi.org/10.1002/pro.2730
32 https://doi.org/10.1016/0735-1097(90)90183-p
33 https://doi.org/10.1016/0735-1097(90)90545-z
34 https://doi.org/10.1016/j.amjcard.2007.11.047
35 https://doi.org/10.1016/j.cell.2012.02.022
36 https://doi.org/10.1016/j.foodchem.2010.04.048
37 https://doi.org/10.1016/j.hoc.2014.08.013
38 https://doi.org/10.1016/j.jcmg.2012.11.013
39 https://doi.org/10.1016/j.jnutbio.2005.03.003
40 https://doi.org/10.1016/j.mito.2009.11.003
41 https://doi.org/10.1016/j.str.2010.02.012
42 https://doi.org/10.1016/s0268-960x(03)00027-4
43 https://doi.org/10.1021/bi1004409
44 https://doi.org/10.1021/jf0522199
45 https://doi.org/10.1021/jm400161p
46 https://doi.org/10.1056/nejmoa070484
47 https://doi.org/10.1056/nejmoa1504942
48 https://doi.org/10.1056/nejmra023144
49 https://doi.org/10.1073/pnas.0910723107
50 https://doi.org/10.1073/pnas.0912263107
51 https://doi.org/10.1074/jbc.m116.736736
52 https://doi.org/10.1093/eurheartj/ehu444
53 https://doi.org/10.1093/jn/131.12.3208
54 https://doi.org/10.1093/qjmed/91.2.141
55 https://doi.org/10.1097/tp.0b013e3181f10edb
56 https://doi.org/10.1111/j.1600-6143.2009.02643.x
57 https://doi.org/10.1111/j.1600-6143.2010.03227.x
58 https://doi.org/10.1136/hrt.2009.190405
59 https://doi.org/10.1152/ajpheart.00186.2013
60 https://doi.org/10.1152/ajpheart.00815.2011
61 https://doi.org/10.1158/1078-0432.ccr-04-2549
62 https://doi.org/10.1159/000320201
63 https://doi.org/10.1161/01.cir.0000068313.67758.4f
64 https://doi.org/10.1161/01.cir.63.1.188
65 https://doi.org/10.1161/01.cir.73.2.249
66 https://doi.org/10.1161/01.res.0000126569.75419.74
67 https://doi.org/10.1161/circ.104.14.1594
68 https://doi.org/10.1161/circimaging.112.978627
69 https://doi.org/10.1161/circulationaha.104.489187
70 https://doi.org/10.1182/blood-2005-11-4385
71 https://doi.org/10.1182/blood-2006-05-022814
72 https://doi.org/10.1182/blood-2006-07-035352
73 https://doi.org/10.1182/blood-2007-05-089243
74 https://doi.org/10.1182/blood-2009-07-230722
75 https://doi.org/10.1182/blood-2011-01-330738
76 https://doi.org/10.1182/blood-2011-04-351643
77 https://doi.org/10.1182/blood-2011-05-355784
78 https://doi.org/10.1182/blood-2012-02-413161
79 https://doi.org/10.1182/blood-2013-10-525634
80 https://doi.org/10.1182/blood-2014-04-568329
81 https://doi.org/10.1182/blood-2014-04-570010
82 https://doi.org/10.1200/jco.2004.03.029
83 https://doi.org/10.1200/jco.2008.21.1284
84 https://doi.org/10.1200/jco.2010.32.2271
85 https://doi.org/10.1200/jco.2011.37.7614
86 https://doi.org/10.1200/jco.2011.38.5724
87 https://doi.org/10.1200/jco.2015.63.6530
88 https://doi.org/10.1271/bbb.90195
89 https://doi.org/10.1371/journal.pone.0137716
90 https://doi.org/10.1523/jneurosci.1521-05.2005
91 https://doi.org/10.15252/emmm.201404190
92 https://doi.org/10.2174/1568026611212220007
93 https://doi.org/10.2353/ajpath.2006.060183
94 https://doi.org/10.3109/10428194.2010.524329
95 https://doi.org/10.3109/13506129.2012.733741
96 https://doi.org/10.3109/13506129.2015.1113167
97 https://doi.org/10.3324/haematol.2013.095463
98 https://doi.org/10.3999/jscpt.43.9
99 https://doi.org/10.4142/jvs.2007.8.2.121
100 schema:datePublished 2017-03
101 schema:datePublishedReg 2017-03-01
102 schema:description Previous studies have suggested that an increase in mitochondrial reactive oxygen species may cause organ damage in patients with light-chain (AL) amyloidosis; however, this damage can be decreased by antioxidant-agent treatment. Epigallocatechin gallate (EGCG), the major natural catechin in green tea, has potent antioxidant activity. Because EGCG has recently been reported to have a favorable toxicity profile for treating amyloidosis, we sought to examine the clinical efficacy and toxicity of EGCG in patients with AL amyloidosis. Fifty-seven patients were randomly assigned to the EGCG and observation groups and observed for six months. There were no increases in grade 3-5 adverse events and EGCG therapy was well tolerated. Although a decrease in the urinary albumin level was found in the EGCG group in patients with obvious albuminuria after treatment initiation, its antioxidant activity may not be sufficient to clarify the potential effect of EGCG in patients with AL amyloidosis. Because some of the biological markers responsible for organ damage were well correlated to the level of antioxidant potential in patients' plasma, the status of oxidative stress in the blood may indicate the extent of organ damage in clinical situations.
103 schema:genre research_article
104 schema:inLanguage en
105 schema:isAccessibleForFree false
106 schema:isPartOf N4c88e2cade304c25877cf4a28a7c3f4a
107 Nae4647da306f4195b00211045011b528
108 sg:journal.1076985
109 schema:name Phase 2 trial of daily, oral epigallocatechin gallate in patients with light-chain amyloidosis
110 schema:pagination 295-308
111 schema:productId N0d68df1f6c594ca3816dcc9f573a46c4
112 N1273f412ea804d758fb64637e0bb86bd
113 N4bdce6e3118a42a48ec1c93cf063d439
114 Nb0833e60f7a5410186527b63bcadc6e7
115 Ne315416372c54cf7ba45797932bb66a5
116 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035478151
117 https://doi.org/10.1007/s12185-016-2112-1
118 schema:sdDatePublished 2019-04-11T12:39
119 schema:sdLicense https://scigraph.springernature.com/explorer/license/
120 schema:sdPublisher N4e1fb30185e44f01a9cf1bb0747e493f
121 schema:url https://link.springer.com/10.1007%2Fs12185-016-2112-1
122 sgo:license sg:explorer/license/
123 sgo:sdDataset articles
124 rdf:type schema:ScholarlyArticle
125 N0c94cf4ae91f4e43bf71622d7a2f045f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Aged
127 rdf:type schema:DefinedTerm
128 N0d68df1f6c594ca3816dcc9f573a46c4 schema:name doi
129 schema:value 10.1007/s12185-016-2112-1
130 rdf:type schema:PropertyValue
131 N1273f412ea804d758fb64637e0bb86bd schema:name readcube_id
132 schema:value a900bcec4ecb90463df2f09fe060d3bf6851980329f2643e8e310ab1957c9021
133 rdf:type schema:PropertyValue
134 N12ace7c05d7d4e4f8dbbabeaba95c952 rdf:first sg:person.014724732234.38
135 rdf:rest rdf:nil
136 N13d43c40674e4d54af76b1ead36322a1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Amyloidosis
138 rdf:type schema:DefinedTerm
139 N1648215f0060419e94a9ba19055a7bf1 rdf:first sg:person.01023004677.98
140 rdf:rest N9e29da2bd44e4d5ea83d8204e148132d
141 N22719064450643568ebb20d280e21ed6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Adult
143 rdf:type schema:DefinedTerm
144 N2fb1b15cdfcf41a788977cef686a1289 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Treatment Outcome
146 rdf:type schema:DefinedTerm
147 N3551d93e4f34495d9eda950f9ad4e4ca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Tea
149 rdf:type schema:DefinedTerm
150 N3590a4d726df4b2bb914390242a811c0 rdf:first sg:person.01305523257.35
151 rdf:rest N1648215f0060419e94a9ba19055a7bf1
152 N3766fe83a0f949508f8d0dee70aaee49 rdf:first N70e9d7b7e3af4856baf3cb575867eee0
153 rdf:rest N51664d1f1cf646f6a9935fe5f9a228f3
154 N39f56b8484774443b778ff96d7c4684a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Male
156 rdf:type schema:DefinedTerm
157 N3b0cccac620b49fc8a01fbe8d4d065dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Antioxidants
159 rdf:type schema:DefinedTerm
160 N49af551c25344c57a64b0a9e099f2b22 schema:name Central Research Institute, ITO EN, Ltd, Makinohara, Japan
161 rdf:type schema:Organization
162 N4bdce6e3118a42a48ec1c93cf063d439 schema:name dimensions_id
163 schema:value pub.1035478151
164 rdf:type schema:PropertyValue
165 N4c88e2cade304c25877cf4a28a7c3f4a schema:issueNumber 3
166 rdf:type schema:PublicationIssue
167 N4e1fb30185e44f01a9cf1bb0747e493f schema:name Springer Nature - SN SciGraph project
168 rdf:type schema:Organization
169 N51664d1f1cf646f6a9935fe5f9a228f3 rdf:first sg:person.01022514742.86
170 rdf:rest N6a97fe66966f40dc89c6ae9b648ab501
171 N56de0a07952041f4accbcb04bde438fa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Reactive Oxygen Species
173 rdf:type schema:DefinedTerm
174 N60018edec730448fb654de9803962b68 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Aged, 80 and over
176 rdf:type schema:DefinedTerm
177 N67f3e8043d25475bab65dd7261120b29 rdf:first sg:person.0730703067.74
178 rdf:rest N12ace7c05d7d4e4f8dbbabeaba95c952
179 N6a97fe66966f40dc89c6ae9b648ab501 rdf:first sg:person.01330073613.04
180 rdf:rest N97e9d9cb27df4787be7437637c8bb1bd
181 N70e9d7b7e3af4856baf3cb575867eee0 schema:affiliation https://www.grid.ac/institutes/grid.444497.e
182 schema:familyName Goto
183 schema:givenName Miku
184 rdf:type schema:Person
185 N87b0c2f8843d4227b7e2a67e619c6b5f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Humans
187 rdf:type schema:DefinedTerm
188 N97e9d9cb27df4787be7437637c8bb1bd rdf:first sg:person.01206437067.45
189 rdf:rest Nfccea5a08c5e49028579be23a2352b92
190 N9e29da2bd44e4d5ea83d8204e148132d rdf:first sg:person.07643060755.91
191 rdf:rest N3766fe83a0f949508f8d0dee70aaee49
192 Na1b1863e43c840bf82e890477bf90a5c schema:name Central Research Institute, ITO EN, Ltd, Makinohara, Japan
193 rdf:type schema:Organization
194 Na733ae383dbd48c98a29e930b52ede83 schema:name Central Research Institute, ITO EN, Ltd, Makinohara, Japan
195 rdf:type schema:Organization
196 Nae4647da306f4195b00211045011b528 schema:volumeNumber 105
197 rdf:type schema:PublicationVolume
198 Nb0833e60f7a5410186527b63bcadc6e7 schema:name nlm_unique_id
199 schema:value 9111627
200 rdf:type schema:PropertyValue
201 Nbf143b3f3f514bbca09819f7c9a07631 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
202 schema:name Oxidative Stress
203 rdf:type schema:DefinedTerm
204 Nc3ccb9b1025449bd8cf6d9b1de82ebca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
205 schema:name Female
206 rdf:type schema:DefinedTerm
207 Nca34b2c53fbd4706b252176c17f2100c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
208 schema:name Middle Aged
209 rdf:type schema:DefinedTerm
210 Nd31888c9cad541a1be623392d5981fb1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
211 schema:name Immunoglobulin Light-chain Amyloidosis
212 rdf:type schema:DefinedTerm
213 Ne315416372c54cf7ba45797932bb66a5 schema:name pubmed_id
214 schema:value 27815860
215 rdf:type schema:PropertyValue
216 Nfccea5a08c5e49028579be23a2352b92 rdf:first sg:person.01125477724.18
217 rdf:rest N67f3e8043d25475bab65dd7261120b29
218 Nfeb18761fc4c461e890cc75d47f3964f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
219 schema:name Catechin
220 rdf:type schema:DefinedTerm
221 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
222 schema:name Medical and Health Sciences
223 rdf:type schema:DefinedTerm
224 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
225 schema:name Clinical Sciences
226 rdf:type schema:DefinedTerm
227 sg:journal.1076985 schema:issn 0925-5710
228 1865-3774
229 schema:name International Journal of Hematology
230 rdf:type schema:Periodical
231 sg:person.01022514742.86 schema:affiliation N49af551c25344c57a64b0a9e099f2b22
232 schema:familyName Kobayashi
233 schema:givenName Makoto
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022514742.86
235 rdf:type schema:Person
236 sg:person.01023004677.98 schema:affiliation https://www.grid.ac/institutes/grid.414929.3
237 schema:familyName Shingaki
238 schema:givenName Sumito
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023004677.98
240 rdf:type schema:Person
241 sg:person.01125477724.18 schema:affiliation https://www.grid.ac/institutes/grid.444497.e
242 schema:familyName Wada
243 schema:givenName Yasuyo
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125477724.18
245 rdf:type schema:Person
246 sg:person.01206437067.45 schema:affiliation Na1b1863e43c840bf82e890477bf90a5c
247 schema:familyName Sagesaka
248 schema:givenName Yuko M.
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01206437067.45
250 rdf:type schema:Person
251 sg:person.01305523257.35 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
252 schema:familyName Meshitsuka
253 schema:givenName Sohsuke
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305523257.35
255 rdf:type schema:Person
256 sg:person.01330073613.04 schema:affiliation Na733ae383dbd48c98a29e930b52ede83
257 schema:familyName Ukawa
258 schema:givenName Yuuichi
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330073613.04
260 rdf:type schema:Person
261 sg:person.014724732234.38 schema:affiliation https://www.grid.ac/institutes/grid.414929.3
262 schema:familyName Suzuki
263 schema:givenName Kenshi
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014724732234.38
265 rdf:type schema:Person
266 sg:person.0730703067.74 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
267 schema:familyName Nojima
268 schema:givenName Masanori
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730703067.74
270 rdf:type schema:Person
271 sg:person.07643060755.91 schema:affiliation https://www.grid.ac/institutes/grid.45203.30
272 schema:familyName Hotta
273 schema:givenName Masatoshi
274 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07643060755.91
275 rdf:type schema:Person
276 sg:pub.10.1007/s00277-011-1244-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1010504326
277 https://doi.org/10.1007/s00277-011-1244-x
278 rdf:type schema:CreativeWork
279 sg:pub.10.1007/s00392-008-0649-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007455323
280 https://doi.org/10.1007/s00392-008-0649-6
281 rdf:type schema:CreativeWork
282 sg:pub.10.1007/s00392-010-0142-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1013784425
283 https://doi.org/10.1007/s00392-010-0142-x
284 rdf:type schema:CreativeWork
285 sg:pub.10.1007/s00395-013-0378-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008971897
286 https://doi.org/10.1007/s00395-013-0378-5
287 rdf:type schema:CreativeWork
288 sg:pub.10.1007/s11033-016-4022-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1051925206
289 https://doi.org/10.1007/s11033-016-4022-y
290 rdf:type schema:CreativeWork
291 sg:pub.10.1038/bmt.2012.170 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000671960
292 https://doi.org/10.1038/bmt.2012.170
293 rdf:type schema:CreativeWork
294 sg:pub.10.1038/nsmb.1437 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005415073
295 https://doi.org/10.1038/nsmb.1437
296 rdf:type schema:CreativeWork
297 sg:pub.10.1038/sj.bmt.1704691 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040030206
298 https://doi.org/10.1038/sj.bmt.1704691
299 rdf:type schema:CreativeWork
300 sg:pub.10.1163/156856700x00769 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035074621
301 https://doi.org/10.1163/156856700x00769
302 rdf:type schema:CreativeWork
303 https://app.dimensions.ai/details/publication/pub.1074498098 schema:CreativeWork
304 https://doi.org/10.1002/ajh.20381 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002848933
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1002/cncr.27719 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024667466
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1002/pro.2730 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025901868
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1016/0735-1097(90)90183-p schema:sameAs https://app.dimensions.ai/details/publication/pub.1001123098
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1016/0735-1097(90)90545-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1039690433
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1016/j.amjcard.2007.11.047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042031424
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1016/j.cell.2012.02.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004054282
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1016/j.foodchem.2010.04.048 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028080156
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1016/j.hoc.2014.08.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023127744
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1016/j.jcmg.2012.11.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052202417
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1016/j.jnutbio.2005.03.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015779657
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1016/j.mito.2009.11.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019537189
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1016/j.str.2010.02.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028098222
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1016/s0268-960x(03)00027-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015241684
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1021/bi1004409 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055203165
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1021/jf0522199 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055904392
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1021/jm400161p schema:sameAs https://app.dimensions.ai/details/publication/pub.1018459361
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1056/nejmoa070484 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031535131
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1056/nejmoa1504942 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051001137
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1056/nejmra023144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044393230
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1073/pnas.0910723107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041032441
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1073/pnas.0912263107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047827748
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1074/jbc.m116.736736 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058215156
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1093/eurheartj/ehu444 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040905674
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1093/jn/131.12.3208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074962597
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1093/qjmed/91.2.141 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017665623
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1097/tp.0b013e3181f10edb schema:sameAs https://app.dimensions.ai/details/publication/pub.1052194145
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1111/j.1600-6143.2009.02643.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1022454495
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1111/j.1600-6143.2010.03227.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021165951
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1136/hrt.2009.190405 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003622544
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1152/ajpheart.00186.2013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037254834
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1152/ajpheart.00815.2011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008071002
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1158/1078-0432.ccr-04-2549 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001008566
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1159/000320201 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025033045
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1161/01.cir.0000068313.67758.4f schema:sameAs https://app.dimensions.ai/details/publication/pub.1040255511
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1161/01.cir.63.1.188 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019630398
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1161/01.cir.73.2.249 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040806401
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1161/01.res.0000126569.75419.74 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049323053
379 rdf:type schema:CreativeWork
380 https://doi.org/10.1161/circ.104.14.1594 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074888066
381 rdf:type schema:CreativeWork
382 https://doi.org/10.1161/circimaging.112.978627 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024381419
383 rdf:type schema:CreativeWork
384 https://doi.org/10.1161/circulationaha.104.489187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023531372
385 rdf:type schema:CreativeWork
386 https://doi.org/10.1182/blood-2005-11-4385 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044573091
387 rdf:type schema:CreativeWork
388 https://doi.org/10.1182/blood-2006-05-022814 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032212284
389 rdf:type schema:CreativeWork
390 https://doi.org/10.1182/blood-2006-07-035352 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031509094
391 rdf:type schema:CreativeWork
392 https://doi.org/10.1182/blood-2007-05-089243 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027025880
393 rdf:type schema:CreativeWork
394 https://doi.org/10.1182/blood-2009-07-230722 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027383713
395 rdf:type schema:CreativeWork
396 https://doi.org/10.1182/blood-2011-01-330738 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037479683
397 rdf:type schema:CreativeWork
398 https://doi.org/10.1182/blood-2011-04-351643 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016533109
399 rdf:type schema:CreativeWork
400 https://doi.org/10.1182/blood-2011-05-355784 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049758352
401 rdf:type schema:CreativeWork
402 https://doi.org/10.1182/blood-2012-02-413161 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001203356
403 rdf:type schema:CreativeWork
404 https://doi.org/10.1182/blood-2013-10-525634 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019794653
405 rdf:type schema:CreativeWork
406 https://doi.org/10.1182/blood-2014-04-568329 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041595513
407 rdf:type schema:CreativeWork
408 https://doi.org/10.1182/blood-2014-04-570010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012674514
409 rdf:type schema:CreativeWork
410 https://doi.org/10.1200/jco.2004.03.029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021510596
411 rdf:type schema:CreativeWork
412 https://doi.org/10.1200/jco.2008.21.1284 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040014032
413 rdf:type schema:CreativeWork
414 https://doi.org/10.1200/jco.2010.32.2271 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001608170
415 rdf:type schema:CreativeWork
416 https://doi.org/10.1200/jco.2011.37.7614 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002191429
417 rdf:type schema:CreativeWork
418 https://doi.org/10.1200/jco.2011.38.5724 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034788718
419 rdf:type schema:CreativeWork
420 https://doi.org/10.1200/jco.2015.63.6530 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004331863
421 rdf:type schema:CreativeWork
422 https://doi.org/10.1271/bbb.90195 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025358232
423 rdf:type schema:CreativeWork
424 https://doi.org/10.1371/journal.pone.0137716 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050593489
425 rdf:type schema:CreativeWork
426 https://doi.org/10.1523/jneurosci.1521-05.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041769968
427 rdf:type schema:CreativeWork
428 https://doi.org/10.15252/emmm.201404190 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051596813
429 rdf:type schema:CreativeWork
430 https://doi.org/10.2174/1568026611212220007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069194518
431 rdf:type schema:CreativeWork
432 https://doi.org/10.2353/ajpath.2006.060183 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011304877
433 rdf:type schema:CreativeWork
434 https://doi.org/10.3109/10428194.2010.524329 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023881545
435 rdf:type schema:CreativeWork
436 https://doi.org/10.3109/13506129.2012.733741 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035490701
437 rdf:type schema:CreativeWork
438 https://doi.org/10.3109/13506129.2015.1113167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035326945
439 rdf:type schema:CreativeWork
440 https://doi.org/10.3324/haematol.2013.095463 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039671781
441 rdf:type schema:CreativeWork
442 https://doi.org/10.3999/jscpt.43.9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028165366
443 rdf:type schema:CreativeWork
444 https://doi.org/10.4142/jvs.2007.8.2.121 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011935584
445 rdf:type schema:CreativeWork
446 https://www.grid.ac/institutes/grid.26999.3d schema:alternateName University of Tokyo
447 schema:name Center for Translational Research, The Institute of Medical Science Hospital, The University of Tokyo, 4-6-1, Shiroganedai, Minato, Tokyo, Japan
448 Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan
449 rdf:type schema:Organization
450 https://www.grid.ac/institutes/grid.414929.3 schema:alternateName Japanese Red Cross Medical Center
451 schema:name Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan
452 rdf:type schema:Organization
453 https://www.grid.ac/institutes/grid.444497.e schema:alternateName Jumonji University
454 schema:name Laboratory for Clinical Nutrition, Department of Food and Nutrition, Faculty of Human Life, Jumonji University, Niiza, Japan
455 rdf:type schema:Organization
456 https://www.grid.ac/institutes/grid.45203.30 schema:alternateName National Center For Global Health and Medicine
457 schema:name Department of Radiology, National Center for Global Health and Medicine, Tokyo, Japan
458 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...