Successful treatment with mogamulizumab followed by allogeneic hematopoietic stem-cell transplantation in adult T-cell leukemia/lymphoma: a report of two cases View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-12

AUTHORS

Yukie Tsubokura, Atsushi Satake, Masaaki Hotta, Hideaki Yoshimura, Shinya Fujita, Yoshiko Azuma, Takahisa Nakanishi, Aya Nakaya, Tomoki Ito, Kazuyoshi Ishii, Shosaku Nomura

ABSTRACT

A humanized anti-CC chemokine receptor 4 (CCR4) monoclonal antibody, mogamulizumab (MOG), has been shown to be safe and effective in the treatment of relapsed/refractory adult T-cell leukemia/lymphoma (ATLL). MOG depletes ATLL cells as well as regulatory T cells (Tregs), as CCR4 is expressed on these cells as well. In this context, pretransplant treatment with MOG may induce severe graft-versus-host disease (GVHD) in allogeneic hematopoietic stem-cell transplantation (HSCT). However, the influence of MOG on allogeneic HSCT, including its induction of GVHD, is unclear. In this report, we describe two patients treated with MOG who subsequently underwent allogeneic HSCT. They did not develop severe GVHD or treatment-related complications. In addition, we examined the kinetics of Tregs in the second case. Finally, we suggest that the detrimental effects of MOG can be avoided, which should be prospectively evaluated in future studies. More... »

PAGES

744-748

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12185-016-2087-y

DOI

http://dx.doi.org/10.1007/s12185-016-2087-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1033887907

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27573760


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antibodies, Monoclonal, Humanized", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Graft vs Host Disease", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hematopoietic Stem Cell Transplantation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Leukemia-Lymphoma, Adult T-Cell", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "T-Lymphocytes, Regulatory", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transplantation, Homologous", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "First Department of Internal Medicine, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata City, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tsubokura", 
        "givenName": "Yukie", 
        "id": "sg:person.013664611135.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013664611135.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "First Department of Internal Medicine, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata City, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Satake", 
        "givenName": "Atsushi", 
        "id": "sg:person.0623703477.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623703477.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "First Department of Internal Medicine, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata City, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hotta", 
        "givenName": "Masaaki", 
        "id": "sg:person.0731114547.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731114547.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "First Department of Internal Medicine, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata City, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yoshimura", 
        "givenName": "Hideaki", 
        "id": "sg:person.0663001347.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0663001347.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "First Department of Internal Medicine, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata City, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fujita", 
        "givenName": "Shinya", 
        "id": "sg:person.01136332445.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01136332445.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "First Department of Internal Medicine, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata City, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Azuma", 
        "givenName": "Yoshiko", 
        "id": "sg:person.01070661227.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070661227.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "First Department of Internal Medicine, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata City, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakanishi", 
        "givenName": "Takahisa", 
        "id": "sg:person.01057537506.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057537506.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "First Department of Internal Medicine, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata City, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nakaya", 
        "givenName": "Aya", 
        "id": "sg:person.010101326535.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010101326535.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "First Department of Internal Medicine, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata City, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ito", 
        "givenName": "Tomoki", 
        "id": "sg:person.01105254153.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105254153.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "First Department of Internal Medicine, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata City, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ishii", 
        "givenName": "Kazuyoshi", 
        "id": "sg:person.0665642764.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665642764.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kansai Medical University", 
          "id": "https://www.grid.ac/institutes/grid.410783.9", 
          "name": [
            "First Department of Internal Medicine, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata City, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nomura", 
        "givenName": "Shosaku", 
        "id": "sg:person.0637542245.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637542245.62"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/bmt.2015.315", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015476578", 
          "https://doi.org/10.1038/bmt.2015.315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12185-013-1387-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018731755", 
          "https://doi.org/10.1007/s12185-013-1387-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bmt.2015.254", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019393443", 
          "https://doi.org/10.1038/bmt.2015.254"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02983215", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022520678", 
          "https://doi.org/10.1007/bf02983215"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02983215", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022520678", 
          "https://doi.org/10.1007/bf02983215"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.20020399", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022622619"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2011.38.2101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024284414"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/jto.0000000000000364", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025099045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-09-2697", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025469932"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/bjh.13338", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026707461"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-2141.2001.02737.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027121996"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbmt.2013.09.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027684026"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2007.11.9958", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028603535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdf287", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030752103"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2010-07-293795", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035410639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2010-10-311894", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035770977"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2011.37.3472", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036629395"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm915", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037545494", 
          "https://doi.org/10.1038/nm915"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbmt.2016.05.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041362792"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.20020090", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048159245"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-15-0357", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051121419"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-12", 
    "datePublishedReg": "2016-12-01", 
    "description": "A humanized anti-CC chemokine receptor 4 (CCR4) monoclonal antibody, mogamulizumab (MOG), has been shown to be safe and effective in the treatment of relapsed/refractory adult T-cell leukemia/lymphoma (ATLL). MOG depletes ATLL cells as well as regulatory T cells (Tregs), as CCR4 is expressed on these cells as well. In this context, pretransplant treatment with MOG may induce severe graft-versus-host disease (GVHD) in allogeneic hematopoietic stem-cell transplantation (HSCT). However, the influence of MOG on allogeneic HSCT, including its induction of GVHD, is unclear. In this report, we describe two patients treated with MOG who subsequently underwent allogeneic HSCT. They did not develop severe GVHD or treatment-related complications. In addition, we examined the kinetics of Tregs in the second case. Finally, we suggest that the detrimental effects of MOG can be avoided, which should be prospectively evaluated in future studies.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s12185-016-2087-y", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1076985", 
        "issn": [
          "0925-5710", 
          "1865-3774"
        ], 
        "name": "International Journal of Hematology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "104"
      }
    ], 
    "name": "Successful treatment with mogamulizumab followed by allogeneic hematopoietic stem-cell transplantation in adult T-cell leukemia/lymphoma: a report of two cases", 
    "pagination": "744-748", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "a16ee9cdac41ed8fb29c58854ef854eba4305e7db9e38933462422c3cf7807c5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27573760"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9111627"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12185-016-2087-y"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1033887907"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12185-016-2087-y", 
      "https://app.dimensions.ai/details/publication/pub.1033887907"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:37", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000363_0000000363/records_70032_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs12185-016-2087-y"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12185-016-2087-y'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12185-016-2087-y'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12185-016-2087-y'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12185-016-2087-y'


 

This table displays all metadata directly associated to this object as RDF triples.

244 TRIPLES      21 PREDICATES      59 URIs      31 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12185-016-2087-y schema:about N068c8ac1dad14fb1b83d5504216a1c5f
2 N0df09ff68b0e4719b65ca6ae10b0d430
3 N5424e40cf8cd4c5f89c21280fa087c60
4 N7a54a6c2a520481c988f6f4ec0e52543
5 N7fe006ab3a714e88b62db55068a313cc
6 N949f60a2145642eaa942076f80ec7a62
7 N9da30e974ec344bba49036a3dd1bc91d
8 Na7be8b14ce604b098de06f5a17c2c9c9
9 Na8ef9d6025fd40c0932056650d50a529
10 Ndbe5d34d371240bd97ede304e4a0e24c
11 anzsrc-for:11
12 anzsrc-for:1107
13 schema:author Nf9a7405f05a94d668d2f19db579b7cc5
14 schema:citation sg:pub.10.1007/bf02983215
15 sg:pub.10.1007/s12185-013-1387-8
16 sg:pub.10.1038/bmt.2015.254
17 sg:pub.10.1038/bmt.2015.315
18 sg:pub.10.1038/nm915
19 https://doi.org/10.1016/j.bbmt.2013.09.014
20 https://doi.org/10.1016/j.bbmt.2016.05.017
21 https://doi.org/10.1046/j.1365-2141.2001.02737.x
22 https://doi.org/10.1084/jem.20020090
23 https://doi.org/10.1084/jem.20020399
24 https://doi.org/10.1093/annonc/mdf287
25 https://doi.org/10.1097/jto.0000000000000364
26 https://doi.org/10.1111/bjh.13338
27 https://doi.org/10.1158/1078-0432.ccr-09-2697
28 https://doi.org/10.1158/1078-0432.ccr-15-0357
29 https://doi.org/10.1182/blood-2010-07-293795
30 https://doi.org/10.1182/blood-2010-10-311894
31 https://doi.org/10.1200/jco.2007.11.9958
32 https://doi.org/10.1200/jco.2011.37.3472
33 https://doi.org/10.1200/jco.2011.38.2101
34 schema:datePublished 2016-12
35 schema:datePublishedReg 2016-12-01
36 schema:description A humanized anti-CC chemokine receptor 4 (CCR4) monoclonal antibody, mogamulizumab (MOG), has been shown to be safe and effective in the treatment of relapsed/refractory adult T-cell leukemia/lymphoma (ATLL). MOG depletes ATLL cells as well as regulatory T cells (Tregs), as CCR4 is expressed on these cells as well. In this context, pretransplant treatment with MOG may induce severe graft-versus-host disease (GVHD) in allogeneic hematopoietic stem-cell transplantation (HSCT). However, the influence of MOG on allogeneic HSCT, including its induction of GVHD, is unclear. In this report, we describe two patients treated with MOG who subsequently underwent allogeneic HSCT. They did not develop severe GVHD or treatment-related complications. In addition, we examined the kinetics of Tregs in the second case. Finally, we suggest that the detrimental effects of MOG can be avoided, which should be prospectively evaluated in future studies.
37 schema:genre research_article
38 schema:inLanguage en
39 schema:isAccessibleForFree false
40 schema:isPartOf N6d424bf2815f4792b81170aea269d63e
41 N9a768392dcef4f09be9b5c59bce3b04d
42 sg:journal.1076985
43 schema:name Successful treatment with mogamulizumab followed by allogeneic hematopoietic stem-cell transplantation in adult T-cell leukemia/lymphoma: a report of two cases
44 schema:pagination 744-748
45 schema:productId N4e1908e381ce474f9c6d192037378211
46 N7ccd5380fc994c28bce60db040949e30
47 Na83f68ec67e040f58765dc77327db8f0
48 Nde48f8d2b3604ce19630bdd94f300e79
49 Nedacdc0b072e4eee861e6fe52c193f1a
50 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033887907
51 https://doi.org/10.1007/s12185-016-2087-y
52 schema:sdDatePublished 2019-04-11T12:37
53 schema:sdLicense https://scigraph.springernature.com/explorer/license/
54 schema:sdPublisher N8fe85a86b0884b60850fa7a0ddec43a3
55 schema:url https://link.springer.com/10.1007%2Fs12185-016-2087-y
56 sgo:license sg:explorer/license/
57 sgo:sdDataset articles
58 rdf:type schema:ScholarlyArticle
59 N068c8ac1dad14fb1b83d5504216a1c5f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
60 schema:name Transplantation, Homologous
61 rdf:type schema:DefinedTerm
62 N0cbae904cb5b4d02b6f81053cb2c080b rdf:first sg:person.01070661227.21
63 rdf:rest N7a25337af2ac4e59a864fbeb4ed928f5
64 N0df09ff68b0e4719b65ca6ae10b0d430 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
65 schema:name Humans
66 rdf:type schema:DefinedTerm
67 N3ec9c2b9c0c14209ba0f6b4a1d3fe0a3 rdf:first sg:person.010101326535.86
68 rdf:rest N858f3d7b3c054255b1474fba3fcf9c3a
69 N4e1908e381ce474f9c6d192037378211 schema:name doi
70 schema:value 10.1007/s12185-016-2087-y
71 rdf:type schema:PropertyValue
72 N5424e40cf8cd4c5f89c21280fa087c60 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
73 schema:name T-Lymphocytes, Regulatory
74 rdf:type schema:DefinedTerm
75 N6d424bf2815f4792b81170aea269d63e schema:volumeNumber 104
76 rdf:type schema:PublicationVolume
77 N77d98aea65c44d5780f952fe732f904f rdf:first sg:person.01136332445.47
78 rdf:rest N0cbae904cb5b4d02b6f81053cb2c080b
79 N7a25337af2ac4e59a864fbeb4ed928f5 rdf:first sg:person.01057537506.99
80 rdf:rest N3ec9c2b9c0c14209ba0f6b4a1d3fe0a3
81 N7a54a6c2a520481c988f6f4ec0e52543 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Aged
83 rdf:type schema:DefinedTerm
84 N7ccd5380fc994c28bce60db040949e30 schema:name pubmed_id
85 schema:value 27573760
86 rdf:type schema:PropertyValue
87 N7fe006ab3a714e88b62db55068a313cc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Female
89 rdf:type schema:DefinedTerm
90 N858f3d7b3c054255b1474fba3fcf9c3a rdf:first sg:person.01105254153.88
91 rdf:rest Nd25e97209e6044cc984775b039d18a91
92 N8a5f1ce8b4cf4c538a5ee5028e986a25 rdf:first sg:person.0637542245.62
93 rdf:rest rdf:nil
94 N8fe85a86b0884b60850fa7a0ddec43a3 schema:name Springer Nature - SN SciGraph project
95 rdf:type schema:Organization
96 N949f60a2145642eaa942076f80ec7a62 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Antibodies, Monoclonal, Humanized
98 rdf:type schema:DefinedTerm
99 N95b99c7a4c6d4dbabded38392a2ba45d rdf:first sg:person.0663001347.22
100 rdf:rest N77d98aea65c44d5780f952fe732f904f
101 N9a768392dcef4f09be9b5c59bce3b04d schema:issueNumber 6
102 rdf:type schema:PublicationIssue
103 N9da30e974ec344bba49036a3dd1bc91d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Graft vs Host Disease
105 rdf:type schema:DefinedTerm
106 N9e53c5832e5543328a861d7c6d742230 rdf:first sg:person.0731114547.43
107 rdf:rest N95b99c7a4c6d4dbabded38392a2ba45d
108 Na7be8b14ce604b098de06f5a17c2c9c9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Hematopoietic Stem Cell Transplantation
110 rdf:type schema:DefinedTerm
111 Na83f68ec67e040f58765dc77327db8f0 schema:name dimensions_id
112 schema:value pub.1033887907
113 rdf:type schema:PropertyValue
114 Na8ef9d6025fd40c0932056650d50a529 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Leukemia-Lymphoma, Adult T-Cell
116 rdf:type schema:DefinedTerm
117 Nbde4c3a8c69a47acbc03c72426bdbbaf rdf:first sg:person.0623703477.86
118 rdf:rest N9e53c5832e5543328a861d7c6d742230
119 Nd25e97209e6044cc984775b039d18a91 rdf:first sg:person.0665642764.48
120 rdf:rest N8a5f1ce8b4cf4c538a5ee5028e986a25
121 Ndbe5d34d371240bd97ede304e4a0e24c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Middle Aged
123 rdf:type schema:DefinedTerm
124 Nde48f8d2b3604ce19630bdd94f300e79 schema:name readcube_id
125 schema:value a16ee9cdac41ed8fb29c58854ef854eba4305e7db9e38933462422c3cf7807c5
126 rdf:type schema:PropertyValue
127 Nedacdc0b072e4eee861e6fe52c193f1a schema:name nlm_unique_id
128 schema:value 9111627
129 rdf:type schema:PropertyValue
130 Nf9a7405f05a94d668d2f19db579b7cc5 rdf:first sg:person.013664611135.12
131 rdf:rest Nbde4c3a8c69a47acbc03c72426bdbbaf
132 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
133 schema:name Medical and Health Sciences
134 rdf:type schema:DefinedTerm
135 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
136 schema:name Immunology
137 rdf:type schema:DefinedTerm
138 sg:journal.1076985 schema:issn 0925-5710
139 1865-3774
140 schema:name International Journal of Hematology
141 rdf:type schema:Periodical
142 sg:person.010101326535.86 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
143 schema:familyName Nakaya
144 schema:givenName Aya
145 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010101326535.86
146 rdf:type schema:Person
147 sg:person.01057537506.99 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
148 schema:familyName Nakanishi
149 schema:givenName Takahisa
150 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01057537506.99
151 rdf:type schema:Person
152 sg:person.01070661227.21 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
153 schema:familyName Azuma
154 schema:givenName Yoshiko
155 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070661227.21
156 rdf:type schema:Person
157 sg:person.01105254153.88 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
158 schema:familyName Ito
159 schema:givenName Tomoki
160 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01105254153.88
161 rdf:type schema:Person
162 sg:person.01136332445.47 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
163 schema:familyName Fujita
164 schema:givenName Shinya
165 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01136332445.47
166 rdf:type schema:Person
167 sg:person.013664611135.12 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
168 schema:familyName Tsubokura
169 schema:givenName Yukie
170 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013664611135.12
171 rdf:type schema:Person
172 sg:person.0623703477.86 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
173 schema:familyName Satake
174 schema:givenName Atsushi
175 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623703477.86
176 rdf:type schema:Person
177 sg:person.0637542245.62 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
178 schema:familyName Nomura
179 schema:givenName Shosaku
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637542245.62
181 rdf:type schema:Person
182 sg:person.0663001347.22 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
183 schema:familyName Yoshimura
184 schema:givenName Hideaki
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0663001347.22
186 rdf:type schema:Person
187 sg:person.0665642764.48 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
188 schema:familyName Ishii
189 schema:givenName Kazuyoshi
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0665642764.48
191 rdf:type schema:Person
192 sg:person.0731114547.43 schema:affiliation https://www.grid.ac/institutes/grid.410783.9
193 schema:familyName Hotta
194 schema:givenName Masaaki
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731114547.43
196 rdf:type schema:Person
197 sg:pub.10.1007/bf02983215 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022520678
198 https://doi.org/10.1007/bf02983215
199 rdf:type schema:CreativeWork
200 sg:pub.10.1007/s12185-013-1387-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018731755
201 https://doi.org/10.1007/s12185-013-1387-8
202 rdf:type schema:CreativeWork
203 sg:pub.10.1038/bmt.2015.254 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019393443
204 https://doi.org/10.1038/bmt.2015.254
205 rdf:type schema:CreativeWork
206 sg:pub.10.1038/bmt.2015.315 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015476578
207 https://doi.org/10.1038/bmt.2015.315
208 rdf:type schema:CreativeWork
209 sg:pub.10.1038/nm915 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037545494
210 https://doi.org/10.1038/nm915
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1016/j.bbmt.2013.09.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027684026
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1016/j.bbmt.2016.05.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041362792
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1046/j.1365-2141.2001.02737.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1027121996
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1084/jem.20020090 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048159245
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1084/jem.20020399 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022622619
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1093/annonc/mdf287 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030752103
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1097/jto.0000000000000364 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025099045
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1111/bjh.13338 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026707461
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1158/1078-0432.ccr-09-2697 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025469932
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1158/1078-0432.ccr-15-0357 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051121419
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1182/blood-2010-07-293795 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035410639
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1182/blood-2010-10-311894 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035770977
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1200/jco.2007.11.9958 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028603535
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1200/jco.2011.37.3472 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036629395
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1200/jco.2011.38.2101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024284414
241 rdf:type schema:CreativeWork
242 https://www.grid.ac/institutes/grid.410783.9 schema:alternateName Kansai Medical University
243 schema:name First Department of Internal Medicine, Kansai Medical University, 2-5-1 Shinmachi, 573-1010, Hirakata City, Osaka, Japan
244 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...