Clinical usefulness of WT1 mRNA expression in bone marrow detected by a new WT1 mRNA assay kit for monitoring acute ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-01

AUTHORS

Kunio Kitamura, Takahiro Nishiyama, Ken Ishiyama, Shuichi Miyawaki, Kanji Miyazaki, Kenshi Suzuki, Hiroaki Masaie, Masaya Okada, Hiroyasu Ogawa, Kiyotoshi Imai, Hitoshi Kiyoi, Tomoki Naoe, Yasuhisa Yokoyama, Shigeru Chiba, Tomoko Hata, Yasushi Miyazaki, Yoshihiro Hatta, Jin Takeuchi, Yasuhito Nannya, Mineo Kurokawa, Yasunori Ueda, Daisuke Koga, Haruo Sugiyama, Fumimaro Takaku

ABSTRACT

We have previously shown the clinical usefulness of Wilms' tumor 1 gene (WT1) mRNA expression in peripheral blood (PB) as a minimal residual disease (MRD) monitoring marker in 191 acute myeloid leukemia (AML) patients using the WT1 mRNA assay kit "Otsuka" (Otsuka Pharmaceutical Co., Ltd.; "former kit"). In contrast, the usefulness of WT1 mRNA expression in bone marrow (BM) has been investigated in only a limited number of subjects using former kit. Following that previous study, a next-generation kit, WT1 mRNA assay kit II "Otsuka" (Otsuka Pharmaceutical Co., Ltd.; "new kit") has been newly developed. In the present study, we aimed to evaluate the performance of the new kit and to investigate the clinical usefulness of WT1 mRNA expression in BM. The PB and BM were collected on the same day from 164 blood disease patients, including 118 AML patients. WT1 mRNA expression was determined using the new and former kits and the values obtained were compared. The performance of new kit was shown to be equivalent to that of former kit. As reported in PB, WT1 mRNA expression in BM was found to be a useful marker for monitoring disease status as well as for a diagnosis of early stage relapse in AML patients. More... »

PAGES

53-62

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12185-015-1882-1

DOI

http://dx.doi.org/10.1007/s12185-015-1882-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1052295548

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/26520650


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone Marrow", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Leukemia, Myeloid, Acute", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Monitoring, Physiologic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Messenger", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reagent Kits, Diagnostic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "WT1 Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Young Adult", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Division of Hematology, Ichinomiya Municipal Hospital, 2-2-22 Bunkyo Ichinomiya, 491-8558, Aichi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kitamura", 
        "givenName": "Kunio", 
        "id": "sg:person.010731014002.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010731014002.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagoya University", 
          "id": "https://www.grid.ac/institutes/grid.27476.30", 
          "name": [
            "Division of Hematology, Ichinomiya Municipal Hospital, 2-2-22 Bunkyo Ichinomiya, 491-8558, Aichi, Japan", 
            "Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nishiyama", 
        "givenName": "Takahiro", 
        "id": "sg:person.01332473161.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332473161.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kanazawa University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.412002.5", 
          "name": [
            "Division of Hematology, Tokyo Metropolitan Ohtsuka Hospital, Tokyo, Japan", 
            "Department of Hematology, Kanazawa University Hospital, Ishikawa, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ishiyama", 
        "givenName": "Ken", 
        "id": "sg:person.01203713705.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01203713705.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tokyo Metropolitan Ohtsuka Hospital", 
          "id": "https://www.grid.ac/institutes/grid.410806.b", 
          "name": [
            "Division of Hematology, Tokyo Metropolitan Ohtsuka Hospital, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miyawaki", 
        "givenName": "Shuichi", 
        "id": "sg:person.0575627640.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575627640.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Japanese Red Cross Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.414929.3", 
          "name": [
            "Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miyazaki", 
        "givenName": "Kanji", 
        "id": "sg:person.01071120077.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071120077.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Japanese Red Cross Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.414929.3", 
          "name": [
            "Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Suzuki", 
        "givenName": "Kenshi", 
        "id": "sg:person.014724732234.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014724732234.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka Medical Center for Cancer and Cardiovascular Diseases", 
          "id": "https://www.grid.ac/institutes/grid.416963.f", 
          "name": [
            "Department of Hematology and Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Masaie", 
        "givenName": "Hiroaki", 
        "id": "sg:person.0713245521.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713245521.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hyogo College of Medicine", 
          "id": "https://www.grid.ac/institutes/grid.272264.7", 
          "name": [
            "Division of Hematology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Okada", 
        "givenName": "Masaya", 
        "id": "sg:person.0625574366.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625574366.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hyogo College of Medicine", 
          "id": "https://www.grid.ac/institutes/grid.272264.7", 
          "name": [
            "Division of Hematology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ogawa", 
        "givenName": "Hiroyasu", 
        "id": "sg:person.0625547166.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625547166.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Sapporo Hokuyu Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415262.6", 
          "name": [
            "Department of Hematology, Sapporo Hokuyu Hospital, Sapporo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Imai", 
        "givenName": "Kiyotoshi", 
        "id": "sg:person.016551375562.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016551375562.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagoya University", 
          "id": "https://www.grid.ac/institutes/grid.27476.30", 
          "name": [
            "Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kiyoi", 
        "givenName": "Hitoshi", 
        "id": "sg:person.0577356402.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577356402.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagoya Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.410840.9", 
          "name": [
            "Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan", 
            "National Hospital Organization Nagoya Medical Center, Aichi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Naoe", 
        "givenName": "Tomoki", 
        "id": "sg:person.0617447237.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617447237.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tsukuba", 
          "id": "https://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Department of Hematology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yokoyama", 
        "givenName": "Yasuhisa", 
        "id": "sg:person.01130015361.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130015361.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tsukuba", 
          "id": "https://www.grid.ac/institutes/grid.20515.33", 
          "name": [
            "Department of Hematology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chiba", 
        "givenName": "Shigeru", 
        "id": "sg:person.0671177613.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671177613.83"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki University", 
          "id": "https://www.grid.ac/institutes/grid.174567.6", 
          "name": [
            "Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hata", 
        "givenName": "Tomoko", 
        "id": "sg:person.01014505165.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014505165.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagasaki University", 
          "id": "https://www.grid.ac/institutes/grid.174567.6", 
          "name": [
            "Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Miyazaki", 
        "givenName": "Yasushi", 
        "id": "sg:person.012267426162.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012267426162.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nihon University", 
          "id": "https://www.grid.ac/institutes/grid.260969.2", 
          "name": [
            "Department of Hematology and Rheumatology, Nihon University School of Medicine, Itabashi Hospital, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hatta", 
        "givenName": "Yoshihiro", 
        "id": "sg:person.01010357272.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01010357272.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nihon University", 
          "id": "https://www.grid.ac/institutes/grid.260969.2", 
          "name": [
            "Department of Hematology and Rheumatology, Nihon University School of Medicine, Itabashi Hospital, Tokyo, Japan", 
            "Division of Hematology, International University of Health and Welfare Shioya Hospital, Tochigi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takeuchi", 
        "givenName": "Jin", 
        "id": "sg:person.0752260363.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0752260363.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nannya", 
        "givenName": "Yasuhito", 
        "id": "sg:person.0741743646.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741743646.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Tokyo", 
          "id": "https://www.grid.ac/institutes/grid.26999.3d", 
          "name": [
            "Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kurokawa", 
        "givenName": "Mineo", 
        "id": "sg:person.01124305446.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124305446.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Kurashiki Central Hospital", 
          "id": "https://www.grid.ac/institutes/grid.415565.6", 
          "name": [
            "Department of Haematology/Oncology, Transfusion and Haemapheresis Center, Kurashiki Central Hospital, Okayama, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ueda", 
        "givenName": "Yasunori", 
        "id": "sg:person.012702165142.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012702165142.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Otsuka (Japan)", 
          "id": "https://www.grid.ac/institutes/grid.419953.3", 
          "name": [
            "Diagnostic Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Koga", 
        "givenName": "Daisuke", 
        "id": "sg:person.01023722571.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023722571.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Osaka University", 
          "id": "https://www.grid.ac/institutes/grid.136593.b", 
          "name": [
            "Department of Functional Diagnostic Science, Osaka University Graduate School of Medicine, Osaka, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sugiyama", 
        "givenName": "Haruo", 
        "id": "sg:person.0707711670.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707711670.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "The Japanese Association of Medical Sciences, Tokyo, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Takaku", 
        "givenName": "Fumimaro", 
        "id": "sg:person.01067400335.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01067400335.73"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1111/j.1349-7006.1999.tb00733.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002396653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1349-7006.1999.tb00733.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002396653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2141.2004.04952.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006202438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2009.22.4865", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008077664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2402675", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012557459", 
          "https://doi.org/10.1038/sj.leu.2402675"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2402675", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012557459", 
          "https://doi.org/10.1038/sj.leu.2402675"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/10428194.2010.507829", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023012804"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/343774a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028173278", 
          "https://doi.org/10.1038/343774a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2402512", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033321388", 
          "https://doi.org/10.1038/sj.leu.2402512"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2402512", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033321388", 
          "https://doi.org/10.1038/sj.leu.2402512"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(90)90601-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037826092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2141.2008.07132.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038105173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2403809", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040786175", 
          "https://doi.org/10.1038/sj.leu.2403809"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2403809", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040786175", 
          "https://doi.org/10.1038/sj.leu.2403809"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2403809", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040786175", 
          "https://doi.org/10.1038/sj.leu.2403809"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02981935", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041602981", 
          "https://doi.org/10.1007/bf02981935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02981935", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041602981", 
          "https://doi.org/10.1007/bf02981935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02983561", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052422704", 
          "https://doi.org/10.1007/bf02983561"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02983561", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052422704", 
          "https://doi.org/10.1007/bf02983561"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077182454", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078333760", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082578905", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1096/fasebj.7.10.8393820", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082788219"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082966028", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-01", 
    "datePublishedReg": "2016-01-01", 
    "description": "We have previously shown the clinical usefulness of Wilms' tumor 1 gene (WT1) mRNA expression in peripheral blood (PB) as a minimal residual disease (MRD) monitoring marker in 191 acute myeloid leukemia (AML) patients using the WT1 mRNA assay kit \"Otsuka\" (Otsuka Pharmaceutical Co., Ltd.; \"former kit\"). In contrast, the usefulness of WT1 mRNA expression in bone marrow (BM) has been investigated in only a limited number of subjects using former kit. Following that previous study, a next-generation kit, WT1 mRNA assay kit II \"Otsuka\" (Otsuka Pharmaceutical Co., Ltd.; \"new kit\") has been newly developed. In the present study, we aimed to evaluate the performance of the new kit and to investigate the clinical usefulness of WT1 mRNA expression in BM. The PB and BM were collected on the same day from 164 blood disease patients, including 118 AML patients. WT1 mRNA expression was determined using the new and former kits and the values obtained were compared. The performance of new kit was shown to be equivalent to that of former kit. As reported in PB, WT1 mRNA expression in BM was found to be a useful marker for monitoring disease status as well as for a diagnosis of early stage relapse in AML patients. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s12185-015-1882-1", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1076985", 
        "issn": [
          "0925-5710", 
          "1865-3774"
        ], 
        "name": "International Journal of Hematology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "103"
      }
    ], 
    "name": "Clinical usefulness of WT1 mRNA expression in bone marrow detected by a new WT1 mRNA assay kit for monitoring acute myeloid leukemia: a comparison with expression of WT1 mRNA in peripheral blood", 
    "pagination": "53-62", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "f91a157007f29e1f98c20ec6ccad823021dd1dc3d3915e1b5e13b0862c14145b"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "26520650"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9111627"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12185-015-1882-1"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1052295548"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12185-015-1882-1", 
      "https://app.dimensions.ai/details/publication/pub.1052295548"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:13", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8660_00000524.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs12185-015-1882-1"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12185-015-1882-1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12185-015-1882-1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12185-015-1882-1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12185-015-1882-1'


 

This table displays all metadata directly associated to this object as RDF triples.

393 TRIPLES      21 PREDICATES      61 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12185-015-1882-1 schema:about N024449f6db734c94a2a111721120cd3e
2 N164400354e9942bf97cd452c87cd92f5
3 N2b4018966d0741c79e99fb8a7d41da5c
4 N4502eecb3b4f458ebae38806c1b4b09d
5 N45a322bd39ca441990d0246cc78ed4e7
6 N59ce86b963c84d4bbe5b6cc3bcc461cd
7 N8b8c57e54a984cd086fb3b73cc888db6
8 N8b99deabd983443fa36e3212f9171f66
9 N9b4745b17ac74d5784bedf5059190b41
10 Nc0b8139a0e3640f8874c57fd461d1453
11 Nc5dc11f19ea64a30812aae069dccd631
12 Ncd643ca33bdc472fb620f32a7ffd1e4b
13 Nd52817d8da0548daba4d6d3cc88d8bad
14 Ne9287b652fd14751b84f308c3e3d29f4
15 Nea618a039fe14e7a815de55d6c0948cd
16 anzsrc-for:11
17 anzsrc-for:1102
18 schema:author N4dd2cf0c75cc41fda056d1b82af48330
19 schema:citation sg:pub.10.1007/bf02981935
20 sg:pub.10.1007/bf02983561
21 sg:pub.10.1038/343774a0
22 sg:pub.10.1038/sj.leu.2402512
23 sg:pub.10.1038/sj.leu.2402675
24 sg:pub.10.1038/sj.leu.2403809
25 https://app.dimensions.ai/details/publication/pub.1077182454
26 https://app.dimensions.ai/details/publication/pub.1078333760
27 https://app.dimensions.ai/details/publication/pub.1082578905
28 https://app.dimensions.ai/details/publication/pub.1082966028
29 https://doi.org/10.1016/0092-8674(90)90601-a
30 https://doi.org/10.1096/fasebj.7.10.8393820
31 https://doi.org/10.1111/j.1349-7006.1999.tb00733.x
32 https://doi.org/10.1111/j.1365-2141.2004.04952.x
33 https://doi.org/10.1111/j.1365-2141.2008.07132.x
34 https://doi.org/10.1200/jco.2009.22.4865
35 https://doi.org/10.3109/10428194.2010.507829
36 schema:datePublished 2016-01
37 schema:datePublishedReg 2016-01-01
38 schema:description We have previously shown the clinical usefulness of Wilms' tumor 1 gene (WT1) mRNA expression in peripheral blood (PB) as a minimal residual disease (MRD) monitoring marker in 191 acute myeloid leukemia (AML) patients using the WT1 mRNA assay kit "Otsuka" (Otsuka Pharmaceutical Co., Ltd.; "former kit"). In contrast, the usefulness of WT1 mRNA expression in bone marrow (BM) has been investigated in only a limited number of subjects using former kit. Following that previous study, a next-generation kit, WT1 mRNA assay kit II "Otsuka" (Otsuka Pharmaceutical Co., Ltd.; "new kit") has been newly developed. In the present study, we aimed to evaluate the performance of the new kit and to investigate the clinical usefulness of WT1 mRNA expression in BM. The PB and BM were collected on the same day from 164 blood disease patients, including 118 AML patients. WT1 mRNA expression was determined using the new and former kits and the values obtained were compared. The performance of new kit was shown to be equivalent to that of former kit. As reported in PB, WT1 mRNA expression in BM was found to be a useful marker for monitoring disease status as well as for a diagnosis of early stage relapse in AML patients.
39 schema:genre research_article
40 schema:inLanguage en
41 schema:isAccessibleForFree false
42 schema:isPartOf N3fc9f38533624b4a8c14086a1cb33b2e
43 Ne842b409278a42659c2dfa1124cb93ff
44 sg:journal.1076985
45 schema:name Clinical usefulness of WT1 mRNA expression in bone marrow detected by a new WT1 mRNA assay kit for monitoring acute myeloid leukemia: a comparison with expression of WT1 mRNA in peripheral blood
46 schema:pagination 53-62
47 schema:productId N94180414008b46f29abfc7b7a7c642b7
48 N9ddc0fbf49e544ddb07af75439fe65c0
49 Nb3e408b125054e05bb542a2997440e08
50 Ndf65bde084174c41ab9a44f797db1026
51 Ne46eb0f7d4b348aca034ce8cc69b353a
52 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052295548
53 https://doi.org/10.1007/s12185-015-1882-1
54 schema:sdDatePublished 2019-04-10T14:13
55 schema:sdLicense https://scigraph.springernature.com/explorer/license/
56 schema:sdPublisher N315221c2ca20442785da94579fe8c26b
57 schema:url http://link.springer.com/10.1007%2Fs12185-015-1882-1
58 sgo:license sg:explorer/license/
59 sgo:sdDataset articles
60 rdf:type schema:ScholarlyArticle
61 N01a5bf6198ff4836b90dd9006c960837 rdf:first sg:person.0575627640.70
62 rdf:rest Nd46ac1669d72488eb515a85551a292bd
63 N024449f6db734c94a2a111721120cd3e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
64 schema:name Reagent Kits, Diagnostic
65 rdf:type schema:DefinedTerm
66 N0a2d69658b8a4aefb425b0b1f87346fd rdf:first sg:person.014724732234.38
67 rdf:rest Nd0678d41695e4f9d93657d161dd0c789
68 N0fd9a2b021544891b863e2a9e890d079 rdf:first sg:person.01010357272.28
69 rdf:rest N50b4d72f469e42638eb27abb999eb4bb
70 N164400354e9942bf97cd452c87cd92f5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
71 schema:name Monitoring, Physiologic
72 rdf:type schema:DefinedTerm
73 N1b2877339eff4648ad21dc3ef28a4383 rdf:first sg:person.01332473161.31
74 rdf:rest Ne0d05c9e6d7e4d959cdba7da87e42cf9
75 N2b3cf4f9a7464d818168ea2e487ff48f rdf:first sg:person.0671177613.83
76 rdf:rest Nf7343ba9a02644dca478fb5797be273b
77 N2b4018966d0741c79e99fb8a7d41da5c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Leukemia, Myeloid, Acute
79 rdf:type schema:DefinedTerm
80 N315221c2ca20442785da94579fe8c26b schema:name Springer Nature - SN SciGraph project
81 rdf:type schema:Organization
82 N3ab5dd48badb43248298104024e78541 rdf:first sg:person.01130015361.78
83 rdf:rest N2b3cf4f9a7464d818168ea2e487ff48f
84 N3cee708111b44a10a725350512b7ca7c rdf:first sg:person.0625547166.22
85 rdf:rest Ndf911717fbdf41d291be94aa69def4ff
86 N3fc9f38533624b4a8c14086a1cb33b2e schema:issueNumber 1
87 rdf:type schema:PublicationIssue
88 N4502eecb3b4f458ebae38806c1b4b09d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name RNA, Messenger
90 rdf:type schema:DefinedTerm
91 N45a322bd39ca441990d0246cc78ed4e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name WT1 Proteins
93 rdf:type schema:DefinedTerm
94 N4dd2cf0c75cc41fda056d1b82af48330 rdf:first sg:person.010731014002.27
95 rdf:rest N1b2877339eff4648ad21dc3ef28a4383
96 N50b4d72f469e42638eb27abb999eb4bb rdf:first sg:person.0752260363.39
97 rdf:rest Ne25cdfaff2b94d4bb9662aebee83653d
98 N58325a0632354e4299f21dc9fe166ce5 rdf:first sg:person.0617447237.02
99 rdf:rest N3ab5dd48badb43248298104024e78541
100 N59ce86b963c84d4bbe5b6cc3bcc461cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Adult
102 rdf:type schema:DefinedTerm
103 N5ab9133937ef4936a2abcd58a8732f6e rdf:first sg:person.012267426162.55
104 rdf:rest N0fd9a2b021544891b863e2a9e890d079
105 N7e90080d2d9844b39048009b52d12685 rdf:first sg:person.0707711670.90
106 rdf:rest Nbd5296d5873842a58e0d7c480c14bded
107 N84aebc029825477e82994f69cc47657d rdf:first sg:person.0577356402.63
108 rdf:rest N58325a0632354e4299f21dc9fe166ce5
109 N8b8c57e54a984cd086fb3b73cc888db6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Female
111 rdf:type schema:DefinedTerm
112 N8b99deabd983443fa36e3212f9171f66 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Aged, 80 and over
114 rdf:type schema:DefinedTerm
115 N90cf73728f354e35a8536fe8edcabf7f schema:name The Japanese Association of Medical Sciences, Tokyo, Japan
116 rdf:type schema:Organization
117 N94180414008b46f29abfc7b7a7c642b7 schema:name pubmed_id
118 schema:value 26520650
119 rdf:type schema:PropertyValue
120 N9b4745b17ac74d5784bedf5059190b41 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Gene Expression
122 rdf:type schema:DefinedTerm
123 N9ddc0fbf49e544ddb07af75439fe65c0 schema:name dimensions_id
124 schema:value pub.1052295548
125 rdf:type schema:PropertyValue
126 Nb3e408b125054e05bb542a2997440e08 schema:name readcube_id
127 schema:value f91a157007f29e1f98c20ec6ccad823021dd1dc3d3915e1b5e13b0862c14145b
128 rdf:type schema:PropertyValue
129 Nbd5296d5873842a58e0d7c480c14bded rdf:first sg:person.01067400335.73
130 rdf:rest rdf:nil
131 Nc0b8139a0e3640f8874c57fd461d1453 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Middle Aged
133 rdf:type schema:DefinedTerm
134 Nc5dc11f19ea64a30812aae069dccd631 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Male
136 rdf:type schema:DefinedTerm
137 Nc6143bc456ca4203b0ddc3c4c330b90c schema:name Division of Hematology, Ichinomiya Municipal Hospital, 2-2-22 Bunkyo Ichinomiya, 491-8558, Aichi, Japan
138 rdf:type schema:Organization
139 Nc7488f5817d74500820e04974042f8b5 rdf:first sg:person.012702165142.79
140 rdf:rest Nd2ec3c3d3e194ad4b3b86fac76502c1a
141 Ncd643ca33bdc472fb620f32a7ffd1e4b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Bone Marrow
143 rdf:type schema:DefinedTerm
144 Nd0678d41695e4f9d93657d161dd0c789 rdf:first sg:person.0713245521.45
145 rdf:rest Need0598842554da79b4dda8d1e5a5ea1
146 Nd2ec3c3d3e194ad4b3b86fac76502c1a rdf:first sg:person.01023722571.04
147 rdf:rest N7e90080d2d9844b39048009b52d12685
148 Nd46ac1669d72488eb515a85551a292bd rdf:first sg:person.01071120077.58
149 rdf:rest N0a2d69658b8a4aefb425b0b1f87346fd
150 Nd52817d8da0548daba4d6d3cc88d8bad schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Aged
152 rdf:type schema:DefinedTerm
153 Ndf65bde084174c41ab9a44f797db1026 schema:name doi
154 schema:value 10.1007/s12185-015-1882-1
155 rdf:type schema:PropertyValue
156 Ndf911717fbdf41d291be94aa69def4ff rdf:first sg:person.016551375562.50
157 rdf:rest N84aebc029825477e82994f69cc47657d
158 Ne0d05c9e6d7e4d959cdba7da87e42cf9 rdf:first sg:person.01203713705.56
159 rdf:rest N01a5bf6198ff4836b90dd9006c960837
160 Ne25cdfaff2b94d4bb9662aebee83653d rdf:first sg:person.0741743646.50
161 rdf:rest Ne3063f5420d54367b6922859ae38ab99
162 Ne3063f5420d54367b6922859ae38ab99 rdf:first sg:person.01124305446.95
163 rdf:rest Nc7488f5817d74500820e04974042f8b5
164 Ne46eb0f7d4b348aca034ce8cc69b353a schema:name nlm_unique_id
165 schema:value 9111627
166 rdf:type schema:PropertyValue
167 Ne842b409278a42659c2dfa1124cb93ff schema:volumeNumber 103
168 rdf:type schema:PublicationVolume
169 Ne9287b652fd14751b84f308c3e3d29f4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Humans
171 rdf:type schema:DefinedTerm
172 Nea618a039fe14e7a815de55d6c0948cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Young Adult
174 rdf:type schema:DefinedTerm
175 Need0598842554da79b4dda8d1e5a5ea1 rdf:first sg:person.0625574366.23
176 rdf:rest N3cee708111b44a10a725350512b7ca7c
177 Nf7343ba9a02644dca478fb5797be273b rdf:first sg:person.01014505165.38
178 rdf:rest N5ab9133937ef4936a2abcd58a8732f6e
179 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
180 schema:name Medical and Health Sciences
181 rdf:type schema:DefinedTerm
182 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
183 schema:name Cardiorespiratory Medicine and Haematology
184 rdf:type schema:DefinedTerm
185 sg:journal.1076985 schema:issn 0925-5710
186 1865-3774
187 schema:name International Journal of Hematology
188 rdf:type schema:Periodical
189 sg:person.01010357272.28 schema:affiliation https://www.grid.ac/institutes/grid.260969.2
190 schema:familyName Hatta
191 schema:givenName Yoshihiro
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01010357272.28
193 rdf:type schema:Person
194 sg:person.01014505165.38 schema:affiliation https://www.grid.ac/institutes/grid.174567.6
195 schema:familyName Hata
196 schema:givenName Tomoko
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014505165.38
198 rdf:type schema:Person
199 sg:person.01023722571.04 schema:affiliation https://www.grid.ac/institutes/grid.419953.3
200 schema:familyName Koga
201 schema:givenName Daisuke
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023722571.04
203 rdf:type schema:Person
204 sg:person.01067400335.73 schema:affiliation N90cf73728f354e35a8536fe8edcabf7f
205 schema:familyName Takaku
206 schema:givenName Fumimaro
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01067400335.73
208 rdf:type schema:Person
209 sg:person.01071120077.58 schema:affiliation https://www.grid.ac/institutes/grid.414929.3
210 schema:familyName Miyazaki
211 schema:givenName Kanji
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071120077.58
213 rdf:type schema:Person
214 sg:person.010731014002.27 schema:affiliation Nc6143bc456ca4203b0ddc3c4c330b90c
215 schema:familyName Kitamura
216 schema:givenName Kunio
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010731014002.27
218 rdf:type schema:Person
219 sg:person.01124305446.95 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
220 schema:familyName Kurokawa
221 schema:givenName Mineo
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124305446.95
223 rdf:type schema:Person
224 sg:person.01130015361.78 schema:affiliation https://www.grid.ac/institutes/grid.20515.33
225 schema:familyName Yokoyama
226 schema:givenName Yasuhisa
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130015361.78
228 rdf:type schema:Person
229 sg:person.01203713705.56 schema:affiliation https://www.grid.ac/institutes/grid.412002.5
230 schema:familyName Ishiyama
231 schema:givenName Ken
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01203713705.56
233 rdf:type schema:Person
234 sg:person.012267426162.55 schema:affiliation https://www.grid.ac/institutes/grid.174567.6
235 schema:familyName Miyazaki
236 schema:givenName Yasushi
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012267426162.55
238 rdf:type schema:Person
239 sg:person.012702165142.79 schema:affiliation https://www.grid.ac/institutes/grid.415565.6
240 schema:familyName Ueda
241 schema:givenName Yasunori
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012702165142.79
243 rdf:type schema:Person
244 sg:person.01332473161.31 schema:affiliation https://www.grid.ac/institutes/grid.27476.30
245 schema:familyName Nishiyama
246 schema:givenName Takahiro
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332473161.31
248 rdf:type schema:Person
249 sg:person.014724732234.38 schema:affiliation https://www.grid.ac/institutes/grid.414929.3
250 schema:familyName Suzuki
251 schema:givenName Kenshi
252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014724732234.38
253 rdf:type schema:Person
254 sg:person.016551375562.50 schema:affiliation https://www.grid.ac/institutes/grid.415262.6
255 schema:familyName Imai
256 schema:givenName Kiyotoshi
257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016551375562.50
258 rdf:type schema:Person
259 sg:person.0575627640.70 schema:affiliation https://www.grid.ac/institutes/grid.410806.b
260 schema:familyName Miyawaki
261 schema:givenName Shuichi
262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0575627640.70
263 rdf:type schema:Person
264 sg:person.0577356402.63 schema:affiliation https://www.grid.ac/institutes/grid.27476.30
265 schema:familyName Kiyoi
266 schema:givenName Hitoshi
267 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577356402.63
268 rdf:type schema:Person
269 sg:person.0617447237.02 schema:affiliation https://www.grid.ac/institutes/grid.410840.9
270 schema:familyName Naoe
271 schema:givenName Tomoki
272 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617447237.02
273 rdf:type schema:Person
274 sg:person.0625547166.22 schema:affiliation https://www.grid.ac/institutes/grid.272264.7
275 schema:familyName Ogawa
276 schema:givenName Hiroyasu
277 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625547166.22
278 rdf:type schema:Person
279 sg:person.0625574366.23 schema:affiliation https://www.grid.ac/institutes/grid.272264.7
280 schema:familyName Okada
281 schema:givenName Masaya
282 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625574366.23
283 rdf:type schema:Person
284 sg:person.0671177613.83 schema:affiliation https://www.grid.ac/institutes/grid.20515.33
285 schema:familyName Chiba
286 schema:givenName Shigeru
287 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671177613.83
288 rdf:type schema:Person
289 sg:person.0707711670.90 schema:affiliation https://www.grid.ac/institutes/grid.136593.b
290 schema:familyName Sugiyama
291 schema:givenName Haruo
292 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707711670.90
293 rdf:type schema:Person
294 sg:person.0713245521.45 schema:affiliation https://www.grid.ac/institutes/grid.416963.f
295 schema:familyName Masaie
296 schema:givenName Hiroaki
297 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713245521.45
298 rdf:type schema:Person
299 sg:person.0741743646.50 schema:affiliation https://www.grid.ac/institutes/grid.26999.3d
300 schema:familyName Nannya
301 schema:givenName Yasuhito
302 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741743646.50
303 rdf:type schema:Person
304 sg:person.0752260363.39 schema:affiliation https://www.grid.ac/institutes/grid.260969.2
305 schema:familyName Takeuchi
306 schema:givenName Jin
307 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0752260363.39
308 rdf:type schema:Person
309 sg:pub.10.1007/bf02981935 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041602981
310 https://doi.org/10.1007/bf02981935
311 rdf:type schema:CreativeWork
312 sg:pub.10.1007/bf02983561 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052422704
313 https://doi.org/10.1007/bf02983561
314 rdf:type schema:CreativeWork
315 sg:pub.10.1038/343774a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028173278
316 https://doi.org/10.1038/343774a0
317 rdf:type schema:CreativeWork
318 sg:pub.10.1038/sj.leu.2402512 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033321388
319 https://doi.org/10.1038/sj.leu.2402512
320 rdf:type schema:CreativeWork
321 sg:pub.10.1038/sj.leu.2402675 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012557459
322 https://doi.org/10.1038/sj.leu.2402675
323 rdf:type schema:CreativeWork
324 sg:pub.10.1038/sj.leu.2403809 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040786175
325 https://doi.org/10.1038/sj.leu.2403809
326 rdf:type schema:CreativeWork
327 https://app.dimensions.ai/details/publication/pub.1077182454 schema:CreativeWork
328 https://app.dimensions.ai/details/publication/pub.1078333760 schema:CreativeWork
329 https://app.dimensions.ai/details/publication/pub.1082578905 schema:CreativeWork
330 https://app.dimensions.ai/details/publication/pub.1082966028 schema:CreativeWork
331 https://doi.org/10.1016/0092-8674(90)90601-a schema:sameAs https://app.dimensions.ai/details/publication/pub.1037826092
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1096/fasebj.7.10.8393820 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082788219
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1111/j.1349-7006.1999.tb00733.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1002396653
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1111/j.1365-2141.2004.04952.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006202438
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1111/j.1365-2141.2008.07132.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1038105173
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1200/jco.2009.22.4865 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008077664
342 rdf:type schema:CreativeWork
343 https://doi.org/10.3109/10428194.2010.507829 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023012804
344 rdf:type schema:CreativeWork
345 https://www.grid.ac/institutes/grid.136593.b schema:alternateName Osaka University
346 schema:name Department of Functional Diagnostic Science, Osaka University Graduate School of Medicine, Osaka, Japan
347 rdf:type schema:Organization
348 https://www.grid.ac/institutes/grid.174567.6 schema:alternateName Nagasaki University
349 schema:name Department of Hematology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan
350 rdf:type schema:Organization
351 https://www.grid.ac/institutes/grid.20515.33 schema:alternateName University of Tsukuba
352 schema:name Department of Hematology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
353 rdf:type schema:Organization
354 https://www.grid.ac/institutes/grid.260969.2 schema:alternateName Nihon University
355 schema:name Department of Hematology and Rheumatology, Nihon University School of Medicine, Itabashi Hospital, Tokyo, Japan
356 Division of Hematology, International University of Health and Welfare Shioya Hospital, Tochigi, Japan
357 rdf:type schema:Organization
358 https://www.grid.ac/institutes/grid.26999.3d schema:alternateName University of Tokyo
359 schema:name Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
360 rdf:type schema:Organization
361 https://www.grid.ac/institutes/grid.272264.7 schema:alternateName Hyogo College of Medicine
362 schema:name Division of Hematology, Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
363 rdf:type schema:Organization
364 https://www.grid.ac/institutes/grid.27476.30 schema:alternateName Nagoya University
365 schema:name Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan
366 Division of Hematology, Ichinomiya Municipal Hospital, 2-2-22 Bunkyo Ichinomiya, 491-8558, Aichi, Japan
367 rdf:type schema:Organization
368 https://www.grid.ac/institutes/grid.410806.b schema:alternateName Tokyo Metropolitan Ohtsuka Hospital
369 schema:name Division of Hematology, Tokyo Metropolitan Ohtsuka Hospital, Tokyo, Japan
370 rdf:type schema:Organization
371 https://www.grid.ac/institutes/grid.410840.9 schema:alternateName Nagoya Medical Center
372 schema:name Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Aichi, Japan
373 National Hospital Organization Nagoya Medical Center, Aichi, Japan
374 rdf:type schema:Organization
375 https://www.grid.ac/institutes/grid.412002.5 schema:alternateName Kanazawa University Hospital
376 schema:name Department of Hematology, Kanazawa University Hospital, Ishikawa, Japan
377 Division of Hematology, Tokyo Metropolitan Ohtsuka Hospital, Tokyo, Japan
378 rdf:type schema:Organization
379 https://www.grid.ac/institutes/grid.414929.3 schema:alternateName Japanese Red Cross Medical Center
380 schema:name Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan
381 rdf:type schema:Organization
382 https://www.grid.ac/institutes/grid.415262.6 schema:alternateName Sapporo Hokuyu Hospital
383 schema:name Department of Hematology, Sapporo Hokuyu Hospital, Sapporo, Japan
384 rdf:type schema:Organization
385 https://www.grid.ac/institutes/grid.415565.6 schema:alternateName Kurashiki Central Hospital
386 schema:name Department of Haematology/Oncology, Transfusion and Haemapheresis Center, Kurashiki Central Hospital, Okayama, Japan
387 rdf:type schema:Organization
388 https://www.grid.ac/institutes/grid.416963.f schema:alternateName Osaka Medical Center for Cancer and Cardiovascular Diseases
389 schema:name Department of Hematology and Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
390 rdf:type schema:Organization
391 https://www.grid.ac/institutes/grid.419953.3 schema:alternateName Otsuka (Japan)
392 schema:name Diagnostic Division, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan
393 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...