Successful treatment of a pregnant woman with Philadelphia chromosome-positive acute lymphoblastic leukemia View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-01-29

AUTHORS

Yuki Nakajima, Hideyuki Kuwabara, Yukako Hattori, Rika Ohshima, Rika Sakai, Masakazu Kitagawa, Naoto Tomita, Yoshiaki Ishigatsubo, Shin Fujisawa

ABSTRACT

The management of acute leukemia during pregnancy is challenging. Delays in treatment for acute leukemia can adversely affect maternal prognosis, but chemotherapy during pregnancy may induce severe adverse effects on the fetus. Here, we report a case of a pregnant woman with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) who underwent remission induction therapy and successfully delivered a live infant after chemotherapy. The case is a 36-year-old woman diagnosed with Ph+ALL in the 27th week of pregnancy. She underwent remission induction therapy including daunorubicin, vincristine, cyclophosphamide, and prednisolone. Imatinib was not used in the induction therapy. She delivered the infant after one course of chemotherapy. The infant and the patient are both alive now, without any major complications. More... »

PAGES

427-429

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12185-013-1264-5

DOI

http://dx.doi.org/10.1007/s12185-013-1264-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1021602942

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23359302


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