JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Stanford Center for Inherited Cardiovascular Disease, Stanford University School of Medicine, 300 Pasteur Drive, Falk CVRB room 187, Palo Alto, 94305, Stanford, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.168010.e", 
          "name": [
            "Stanford Center for Inherited Cardiovascular Disease, Stanford University School of Medicine, 300 Pasteur Drive, Falk CVRB room 187, Palo Alto, 94305, Stanford, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Reuter", 
        "givenName": "Chloe M.", 
        "id": "sg:person.014063126763.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014063126763.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Stanford Center for Inherited Cardiovascular Disease, Stanford University School of Medicine, 300 Pasteur Drive, Falk CVRB room 187, Palo Alto, 94305, Stanford, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.168010.e", 
          "name": [
            "Stanford Center for Inherited Cardiovascular Disease, Stanford University School of Medicine, 300 Pasteur Drive, Falk CVRB room 187, Palo Alto, 94305, Stanford, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dries", 
        "givenName": "Annika M.", 
        "id": "sg:person.010274246015.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010274246015.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Stanford Center for Inherited Cardiovascular Disease, Stanford University School of Medicine, 300 Pasteur Drive, Falk CVRB room 187, Palo Alto, 94305, Stanford, CA, USA", 
          "id": "http://www.grid.ac/institutes/grid.168010.e", 
          "name": [
            "Stanford Center for Inherited Cardiovascular Disease, Stanford University School of Medicine, 300 Pasteur Drive, Falk CVRB room 187, Palo Alto, 94305, Stanford, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Parikh", 
        "givenName": "Victoria N.", 
        "id": "sg:person.0766362051.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0766362051.46"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/s41431-018-0169-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104239279", 
          "https://doi.org/10.1038/s41431-018-0169-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ejhg.2012.39", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037849164", 
          "https://doi.org/10.1038/ejhg.2012.39"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/gim.2013.204", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052857482", 
          "https://doi.org/10.1038/gim.2013.204"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00109-004-0589-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023304838", 
          "https://doi.org/10.1007/s00109-004-0589-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/gim.2015.30", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022229472", 
          "https://doi.org/10.1038/gim.2015.30"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature13127", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002821806", 
          "https://doi.org/10.1038/nature13127"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12471-018-1211-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1110580623", 
          "https://doi.org/10.1007/s12471-018-1211-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10741-018-9743-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107402900", 
          "https://doi.org/10.1007/s10741-018-9743-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/gim.2016.90", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031599674", 
          "https://doi.org/10.1038/gim.2016.90"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12881-015-0167-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019890114", 
          "https://doi.org/10.1186/s12881-015-0167-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/gim.2017.218", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100161480", 
          "https://doi.org/10.1038/gim.2017.218"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11886-019-1224-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1122921011", 
          "https://doi.org/10.1007/s11886-019-1224-7"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2021-03-26", 
    "datePublishedReg": "2021-03-26", 
    "description": "Purpose of ReviewArrhythmogenic cardiomyopathy (ACM) represents a collection of cardiomyopathies with etiologies convergent upon highly arrhythmogenic clinical presentations not explained by ischemic, hypertensive, or valvular heart disease. This review describes the current state of knowledge regarding molecular mechanisms and genetic diagnosis in ACM.Recent FindingsClinical manifestations, specifically structural presentations, of ACM may span the right and left side of the heart. The umbrella definition of ACM encompasses disease mechanisms involving disruption of cell-cell adhesion, mechanotransduction, transcription, calcium handling, and post-transcriptional regulators. As such, the underlying genetics are themselves wide ranging but generally map to perturbations of proteins comprising the desmosome and regulating downstream cellular signaling. The recognition that many genetic forms of ACM share the feared outcomes of life-threatening ventricular arrhythmia and heart failure motivates the identification of causative genetic variants for family screening and in some cases precision therapy. In turn, contemporary clinical practice has shifted towards broadened genetic testing strategy and the discovery of complex gene-specific clinical ramifications.SummaryThe molecular mechanisms of ACM are complex, and the genetic architecture is ever evolving. Given this, multidisciplinary patient care for the incorporation of genetics and family cardiovascular care is critical. Future work will refine the understanding of gene-specific outcomes in ACM and implications for tailored therapy.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s12170-021-00669-5", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.8555031", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1039476", 
        "issn": [
          "1932-9520", 
          "1932-9563"
        ], 
        "name": "Current Cardiovascular Risk Reports", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "15"
      }
    ], 
    "keywords": [
      "molecular mechanisms", 
      "post-transcriptional regulators", 
      "cell-cell adhesion", 
      "downstream cellular signaling", 
      "perturbation of proteins", 
      "causative genetic variants", 
      "genetic architecture", 
      "cellular signaling", 
      "life-threatening ventricular arrhythmias", 
      "genetic variants", 
      "valvular heart disease", 
      "genetics", 
      "multidisciplinary patient care", 
      "disease mechanisms", 
      "genetic testing strategies", 
      "contemporary clinical practice", 
      "genetic forms", 
      "heart failure", 
      "clinical presentation", 
      "ventricular arrhythmias", 
      "incorporation of genetics", 
      "heart disease", 
      "family screening", 
      "cardiovascular care", 
      "calcium handling", 
      "genetic diagnosis", 
      "clinical practice", 
      "patient care", 
      "clinical ramifications", 
      "clinical implications", 
      "precision therapy", 
      "structural presentation", 
      "transcription", 
      "cardiomyopathy", 
      "therapy", 
      "mechanotransduction", 
      "mechanism", 
      "signaling", 
      "regulator", 
      "protein", 
      "care", 
      "outcomes", 
      "testing strategies", 
      "umbrella definition", 
      "presentation", 
      "desmosomes", 
      "arrhythmias", 
      "discovery", 
      "etiology", 
      "disruption", 
      "disease", 
      "adhesion", 
      "variants", 
      "diagnosis", 
      "identification", 
      "manifestations", 
      "heart", 
      "screening", 
      "ACM", 
      "review", 
      "failure", 
      "understanding", 
      "perturbations", 
      "current state", 
      "incorporation", 
      "implications", 
      "future work", 
      "turn", 
      "collection", 
      "form", 
      "recognition", 
      "practice", 
      "purpose", 
      "knowledge", 
      "strategies", 
      "ramifications", 
      "side", 
      "architecture", 
      "handling", 
      "definition", 
      "rights", 
      "state", 
      "work"
    ], 
    "name": "Arrhythmogenic Cardiomyopathy: Mechanisms, Genetics, and Their Clinical Implications", 
    "pagination": "7", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1136695432"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12170-021-00669-5"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12170-021-00669-5", 
      "https://app.dimensions.ai/details/publication/pub.1136695432"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-10T10:31", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_882.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s12170-021-00669-5"
  }
]

Download the RDF metadata as:  json-ld nt turtle xml License info

This table displays all metadata directly associated to this object as RDF triples.

213 TRIPLES      22 PREDICATES      122 URIs      100 LITERALS      6 BLANK NODES