Prognostic factors in neoadjuvant treatment followed by surgery in stage IIIA-N2 non-small cell lung cancer: a multi-institutional study by the ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-11-14

AUTHORS

F. Couñago, S. Montemuiño, M. Martin, B. Taboada, P. Calvo-Crespo, M. P. Samper-Ots, P. Alcántara, J. Corona, J. L. López-Guerra, M. Murcia-Mejía, M. López-Mata, J. Jové-Teixidó, M. Chust, V. Díaz-Díaz, L. de Ingunza-Barón, T. García-Cañibano, M. L. Couselo, E. del Cerro, J. Moradiellos, S. Amor, A. Varela, M. M. Puertas, I. J. Thuissard, D. Sanz-Rosa, N. R. de Dios

ABSTRACT

PURPOSE: To evaluate the prognostic factors associated with survival in patients treated with neoadjuvant treatment [chemoradiotherapy (CRT) or chemotherapy] followed by surgery (CRTS) in patients with stage IIIA-N2 non-small cell lung cancer (NSCLC). METHODS: A retrospective study was conducted of 118 patients diagnosed with stage T1-T3N2M0 NSCLC and treated with CRTS at 14 hospitals in Spain between January 2005 and December 2014. Overall survival (OS) and progression-free survival (PFS) were estimated using the Kaplan-Meier method and compared using the log-rank test. Cox regression analysis was performed. RESULTS: Surgery consisted of lobectomy (74.5% of cases), pneumectomy (17.8%), or bilobectomy (7.6%). Neoadjuvant treatment was CRT in 62 patients (52.5%) and chemotherapy alone in 56 patients (47.5%). Median follow-up was 42.5 months (5-128 months). 5-year OS and PFS were 51.1% and 49.4%, respectively. The following variables were independently associated with worse OS and PFS: pneumonectomy (vs. lobectomy); advanced pathologic T stage (pT3 vs. pT0-pT2); and presence of persistent N2 disease (vs. ypN0-1) in the surgical specimen. CONCLUSIONS: In this sample of patients with stage IIIA-N2 NSCLC treated with CRTS, 5-year survival (both OS and PFS) was approximately 50%. After CRTS, the patients with the best prognosis were those whose primary tumour and/or mediastinal nodal metastases were downstaged after induction therapy and those who underwent lobectomy. These findings provide further support for neoadjuvant therapy followed by surgery in selected patients. More... »

PAGES

1-10

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12094-018-1976-3

DOI

http://dx.doi.org/10.1007/s12094-018-1976-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1109906868

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30430394


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "European University of Madrid", 
          "id": "https://www.grid.ac/institutes/grid.119375.8", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitario Quir\u00f3nsalud Madrid, C/ Diego de Vel\u00e1zquez1, 1, Pozuelo de Alarc\u00f3n, 28223, Madrid, Spain", 
            "Universidad Europea de Madrid, Calle Tajo, s/n, Villaviciosa de Od\u00f3n, 28670, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cou\u00f1ago", 
        "givenName": "F.", 
        "id": "sg:person.01112500207.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112500207.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario de Fuenlabrada", 
          "id": "https://www.grid.ac/institutes/grid.411242.0", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitario de Fuenlabrada, Camino del Molino, 2, 28942, Fuenlabrada, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Montemui\u00f1o", 
        "givenName": "S.", 
        "id": "sg:person.07730255311.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07730255311.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Ram\u00f3n y Cajal", 
          "id": "https://www.grid.ac/institutes/grid.411347.4", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitario Ramon y Cajal, Carretera de Colmenar Viejo Km9, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Martin", 
        "givenName": "M.", 
        "id": "sg:person.010450543003.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010450543003.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology, Complexo Hospitalario Universitario Santiago de Compostela, Choupana s/n, bloque d. Santiago de Compostela, A Coru\u00f1a, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Taboada", 
        "givenName": "B.", 
        "id": "sg:person.016547657361.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016547657361.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Radiation Oncology, Complexo Hospitalario Universitario Santiago de Compostela, Choupana s/n, bloque d. Santiago de Compostela, A Coru\u00f1a, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Calvo-Crespo", 
        "givenName": "P.", 
        "id": "sg:person.01333721120.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333721120.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Rey Juan Carlos", 
          "id": "https://www.grid.ac/institutes/grid.459654.f", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitario Rey Juan Carlos, C/Gladiolo s/n. M\u00f3stoles, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Samper-Ots", 
        "givenName": "M. P.", 
        "id": "sg:person.013663552310.50", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013663552310.50"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Cl\u00ednico San Carlos", 
          "id": "https://www.grid.ac/institutes/grid.411068.a", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitario Cl\u00ednico San Carlos, C/Prof, Mart\u00edn Lagos s/n, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Alc\u00e1ntara", 
        "givenName": "P.", 
        "id": "sg:person.01106152460.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106152460.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Cl\u00ednico San Carlos", 
          "id": "https://www.grid.ac/institutes/grid.411068.a", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitario Cl\u00ednico San Carlos, C/Prof, Mart\u00edn Lagos s/n, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Corona", 
        "givenName": "J.", 
        "id": "sg:person.015237435431.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015237435431.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Virgen del Roc\u00edo", 
          "id": "https://www.grid.ac/institutes/grid.411109.c", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitario Virgen del Rocio, Av. Manuel Siurot, S/N, 41013, Seville, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "L\u00f3pez-Guerra", 
        "givenName": "J. L.", 
        "id": "sg:person.0657022205.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657022205.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitari Sant Joan de Reus", 
          "id": "https://www.grid.ac/institutes/grid.411136.0", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitari Sant Joan de Reus, Av. del Dr. Josep Laporte, 2, 43204, Reus, Tarragona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Murcia-Mej\u00eda", 
        "givenName": "M.", 
        "id": "sg:person.01060676471.47", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060676471.47"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Cl\u00ednico Universitario Lozano Blesa", 
          "id": "https://www.grid.ac/institutes/grid.411050.1", 
          "name": [
            "Department of Radiation Oncology, Hospital Clinico Universitario Lozano Blesa, San Juan Bosco 15, Zaragoza, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "L\u00f3pez-Mata", 
        "givenName": "M.", 
        "id": "sg:person.07354663610.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07354663610.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitari Germans Trias i Pujol", 
          "id": "https://www.grid.ac/institutes/grid.411438.b", 
          "name": [
            "Department of Radiation Oncology, Hospital Germans Trias i Pujol, Carretera de Canyet, s/n, 08916, Badalona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jov\u00e9-Teixid\u00f3", 
        "givenName": "J.", 
        "id": "sg:person.013260312544.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013260312544.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Fundaci\u00f3n Instituto Valenciano de Oncolog\u00eda", 
          "id": "https://www.grid.ac/institutes/grid.418082.7", 
          "name": [
            "Department of Radiation Oncology, Instituto Valenciano de Oncologia, Carrer del Professor Beltr\u00e1n B\u00e1guena, 8, 46009, Valencia, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chust", 
        "givenName": "M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Puerta del Mar", 
          "id": "https://www.grid.ac/institutes/grid.411342.1", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitario Puerta del Mar, Av. Ana de Viya, 21, 11009, Cadiz, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "D\u00edaz-D\u00edaz", 
        "givenName": "V.", 
        "id": "sg:person.010007651524.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010007651524.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Puerta del Mar", 
          "id": "https://www.grid.ac/institutes/grid.411342.1", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitario Puerta del Mar, Av. Ana de Viya, 21, 11009, Cadiz, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "de Ingunza-Bar\u00f3n", 
        "givenName": "L.", 
        "id": "sg:person.01066464116.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066464116.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario de Fuenlabrada", 
          "id": "https://www.grid.ac/institutes/grid.411242.0", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitario de Fuenlabrada, Camino del Molino, 2, 28942, Fuenlabrada, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Garc\u00eda-Ca\u00f1ibano", 
        "givenName": "T.", 
        "id": "sg:person.016512722724.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016512722724.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Central de la Defensa G\u00f3mez Ulla", 
          "id": "https://www.grid.ac/institutes/grid.414398.3", 
          "name": [
            "Department of Radiation Oncology, Hospital Central de la Defensa Gomez Ulla, Glorieta Ej\u00e9rcito, 1, 28047, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Couselo", 
        "givenName": "M. L.", 
        "id": "sg:person.011276764371.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011276764371.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "European University of Madrid", 
          "id": "https://www.grid.ac/institutes/grid.119375.8", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitario Quir\u00f3nsalud Madrid, C/ Diego de Vel\u00e1zquez1, 1, Pozuelo de Alarc\u00f3n, 28223, Madrid, Spain", 
            "Universidad Europea de Madrid, Calle Tajo, s/n, Villaviciosa de Od\u00f3n, 28670, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "del Cerro", 
        "givenName": "E.", 
        "id": "sg:person.01041420505.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041420505.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Quir\u00f3nsalud Madrid", 
          "id": "https://www.grid.ac/institutes/grid.488466.0", 
          "name": [
            "Department of Thoracic Surgery, Hospital Universitario Quir\u00f3nsalud Madrid, C/Diego de Vel\u00e1zquez, 1, Pozuelo de Alarc\u00f3n, 28223, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moradiellos", 
        "givenName": "J.", 
        "id": "sg:person.0604703213.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604703213.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Quir\u00f3nsalud Madrid", 
          "id": "https://www.grid.ac/institutes/grid.488466.0", 
          "name": [
            "Department of Thoracic Surgery, Hospital Universitario Quir\u00f3nsalud Madrid, C/Diego de Vel\u00e1zquez, 1, Pozuelo de Alarc\u00f3n, 28223, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Amor", 
        "givenName": "S.", 
        "id": "sg:person.015503443363.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015503443363.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Quir\u00f3nsalud Madrid", 
          "id": "https://www.grid.ac/institutes/grid.488466.0", 
          "name": [
            "Department of Thoracic Surgery, Hospital Universitario Quir\u00f3nsalud Madrid, C/Diego de Vel\u00e1zquez, 1, Pozuelo de Alarc\u00f3n, 28223, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Varela", 
        "givenName": "A.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Miguel Servet", 
          "id": "https://www.grid.ac/institutes/grid.411106.3", 
          "name": [
            "Department of Radiation Oncology, Hospital Universitario Miguel Servet, Paseo Isabel la Cat\u00f3lica, 1-3, 50009, Zaragoza, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Puertas", 
        "givenName": "M. M.", 
        "id": "sg:person.07773620344.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07773620344.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "School of Doctoral Studies and Research, Universidad Europea, Calle Tajo, s/n, Villaviciosa de Od\u00f3n, 28670, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Thuissard", 
        "givenName": "I. J.", 
        "id": "sg:person.01002112707.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002112707.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "School of Doctoral Studies and Research, Universidad Europea, Calle Tajo, s/n, Villaviciosa de Od\u00f3n, 28670, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sanz-Rosa", 
        "givenName": "D.", 
        "id": "sg:person.01157215035.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157215035.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Del Mar", 
          "id": "https://www.grid.ac/institutes/grid.411142.3", 
          "name": [
            "Department of Radiation Oncology, Hospital del Mar. Passeig Mar\u00edtim, 25-29, 08003, Barcelona, Spain", 
            "IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "de Dios", 
        "givenName": "N. R.", 
        "id": "sg:person.016154203151.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016154203151.10"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.jtho.2016.09.122", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003691650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(09)60737-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004597708"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2147/ott.s95511", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009276381"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/djk093", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019816459"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/icvts/ivu141", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021460342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.lungcan.2016.03.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033878468"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.26689", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035566227"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.athoracsur.2008.04.073", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036068306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2015.62.6812", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036512173"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2009.26.2543", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039864167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0039-6109(16)44341-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042606273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/14651858.cd002140.pub3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046701409"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ejcts/ezu504", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059551104"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ejcts/ezv431", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059551486"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ejcts/ezw040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059551579"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/107327481402100108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078830666"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/107327481402100108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078830666"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdu348.1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083557079"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.6004/jnccn.2017.0050", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084819289"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.6004/jnccn.2017.0050", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084819289"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-11-14", 
    "datePublishedReg": "2018-11-14", 
    "description": "PURPOSE: To evaluate the prognostic factors associated with survival in patients treated with neoadjuvant treatment [chemoradiotherapy (CRT) or chemotherapy] followed by surgery (CRTS) in patients with stage IIIA-N2 non-small cell lung cancer (NSCLC).\nMETHODS: A retrospective study was conducted of 118 patients diagnosed with stage T1-T3N2M0 NSCLC and treated with CRTS at 14 hospitals in Spain between January 2005 and December 2014. Overall survival (OS) and progression-free survival (PFS) were estimated using the Kaplan-Meier method and compared using the log-rank test. Cox regression analysis was performed.\nRESULTS: Surgery consisted of lobectomy (74.5% of cases), pneumectomy (17.8%), or bilobectomy (7.6%). Neoadjuvant treatment was CRT in 62 patients (52.5%) and chemotherapy alone in 56 patients (47.5%). Median follow-up was 42.5\u00a0months (5-128\u00a0months). 5-year OS and PFS were 51.1% and 49.4%, respectively. The following variables were independently associated with worse OS and PFS: pneumonectomy (vs. lobectomy); advanced pathologic T stage (pT3 vs. pT0-pT2); and presence of persistent N2 disease (vs. ypN0-1) in the surgical specimen.\nCONCLUSIONS: In this sample of patients with stage IIIA-N2 NSCLC treated with CRTS, 5-year survival (both OS and PFS) was approximately 50%. After CRTS, the patients with the best prognosis were those whose primary tumour and/or mediastinal nodal metastases were downstaged after induction therapy and those who underwent lobectomy. These findings provide further support for neoadjuvant therapy followed by surgery in selected patients.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s12094-018-1976-3", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1035367", 
        "issn": [
          "1699-048X", 
          "1699-3055"
        ], 
        "name": "Clinical and Translational Oncology", 
        "type": "Periodical"
      }
    ], 
    "name": "Prognostic factors in neoadjuvant treatment followed by surgery in stage IIIA-N2 non-small cell lung cancer: a multi-institutional study by the Oncologic Group for the Study of Lung Cancer (Spanish Radiation Oncology Society)", 
    "pagination": "1-10", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "f36020049590105892062f9ce2c27869e81778cf0682c3dd9b6d308fcb317b89"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30430394"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101247119"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12094-018-1976-3"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1109906868"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12094-018-1976-3", 
      "https://app.dimensions.ai/details/publication/pub.1109906868"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T08:07", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000265_0000000265/records_67388_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs12094-018-1976-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12094-018-1976-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12094-018-1976-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12094-018-1976-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12094-018-1976-3'


 

This table displays all metadata directly associated to this object as RDF triples.

335 TRIPLES      21 PREDICATES      44 URIs      18 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12094-018-1976-3 schema:about anzsrc-for:11
2 anzsrc-for:1112
3 schema:author N5592baf53a174f41abe8ec414733015f
4 schema:citation https://doi.org/10.1002/14651858.cd002140.pub3
5 https://doi.org/10.1002/cncr.26689
6 https://doi.org/10.1016/j.athoracsur.2008.04.073
7 https://doi.org/10.1016/j.jtho.2016.09.122
8 https://doi.org/10.1016/j.lungcan.2016.03.016
9 https://doi.org/10.1016/s0039-6109(16)44341-0
10 https://doi.org/10.1016/s0140-6736(09)60737-6
11 https://doi.org/10.1093/annonc/mdu348.1
12 https://doi.org/10.1093/ejcts/ezu504
13 https://doi.org/10.1093/ejcts/ezv431
14 https://doi.org/10.1093/ejcts/ezw040
15 https://doi.org/10.1093/icvts/ivu141
16 https://doi.org/10.1093/jnci/djk093
17 https://doi.org/10.1177/107327481402100108
18 https://doi.org/10.1200/jco.2009.26.2543
19 https://doi.org/10.1200/jco.2015.62.6812
20 https://doi.org/10.2147/ott.s95511
21 https://doi.org/10.6004/jnccn.2017.0050
22 schema:datePublished 2018-11-14
23 schema:datePublishedReg 2018-11-14
24 schema:description PURPOSE: To evaluate the prognostic factors associated with survival in patients treated with neoadjuvant treatment [chemoradiotherapy (CRT) or chemotherapy] followed by surgery (CRTS) in patients with stage IIIA-N2 non-small cell lung cancer (NSCLC). METHODS: A retrospective study was conducted of 118 patients diagnosed with stage T1-T3N2M0 NSCLC and treated with CRTS at 14 hospitals in Spain between January 2005 and December 2014. Overall survival (OS) and progression-free survival (PFS) were estimated using the Kaplan-Meier method and compared using the log-rank test. Cox regression analysis was performed. RESULTS: Surgery consisted of lobectomy (74.5% of cases), pneumectomy (17.8%), or bilobectomy (7.6%). Neoadjuvant treatment was CRT in 62 patients (52.5%) and chemotherapy alone in 56 patients (47.5%). Median follow-up was 42.5 months (5-128 months). 5-year OS and PFS were 51.1% and 49.4%, respectively. The following variables were independently associated with worse OS and PFS: pneumonectomy (vs. lobectomy); advanced pathologic T stage (pT3 vs. pT0-pT2); and presence of persistent N2 disease (vs. ypN0-1) in the surgical specimen. CONCLUSIONS: In this sample of patients with stage IIIA-N2 NSCLC treated with CRTS, 5-year survival (both OS and PFS) was approximately 50%. After CRTS, the patients with the best prognosis were those whose primary tumour and/or mediastinal nodal metastases were downstaged after induction therapy and those who underwent lobectomy. These findings provide further support for neoadjuvant therapy followed by surgery in selected patients.
25 schema:genre research_article
26 schema:inLanguage en
27 schema:isAccessibleForFree false
28 schema:isPartOf sg:journal.1035367
29 schema:name Prognostic factors in neoadjuvant treatment followed by surgery in stage IIIA-N2 non-small cell lung cancer: a multi-institutional study by the Oncologic Group for the Study of Lung Cancer (Spanish Radiation Oncology Society)
30 schema:pagination 1-10
31 schema:productId N1a5fe1cb26b64985ae332a3ff719fe11
32 Na40faa4e54974fd29265b3eeff39827d
33 Naa3c76d10e3f498dbf7ffd63dc6fd2c3
34 Ncd074e8bfbe948fb8fe85d2f75539980
35 Nead2e4fbe0a746cbb000d6dc46a19309
36 schema:sameAs https://app.dimensions.ai/details/publication/pub.1109906868
37 https://doi.org/10.1007/s12094-018-1976-3
38 schema:sdDatePublished 2019-04-11T08:07
39 schema:sdLicense https://scigraph.springernature.com/explorer/license/
40 schema:sdPublisher N539b182740904cd6810bae3edad83f56
41 schema:url https://link.springer.com/10.1007%2Fs12094-018-1976-3
42 sgo:license sg:explorer/license/
43 sgo:sdDataset articles
44 rdf:type schema:ScholarlyArticle
45 N04dd1a798818415c9c5d38487b281b9f rdf:first sg:person.01157215035.22
46 rdf:rest Ne2511d865ac743349228a8a33823de4e
47 N09249b755ebc49c9af8f0e6f717b4d82 rdf:first sg:person.013663552310.50
48 rdf:rest Nf0b40e6dc8c04412badb2ad600bdd0b8
49 N09ed100654f24b219e610207bafa1e83 rdf:first sg:person.01002112707.49
50 rdf:rest N04dd1a798818415c9c5d38487b281b9f
51 N0b99a8c73c3f4cba8fe485514b90e7a9 rdf:first sg:person.015503443363.37
52 rdf:rest Ndddcfcef57444730b286a393fac257c2
53 N1135177346d848e7aabdd5874d2727c2 schema:name School of Doctoral Studies and Research, Universidad Europea, Calle Tajo, s/n, Villaviciosa de Odón, 28670, Madrid, Spain
54 rdf:type schema:Organization
55 N1a5fe1cb26b64985ae332a3ff719fe11 schema:name dimensions_id
56 schema:value pub.1109906868
57 rdf:type schema:PropertyValue
58 N20d8148a1a7f44bab3bfab154c7196ec rdf:first sg:person.0604703213.28
59 rdf:rest N0b99a8c73c3f4cba8fe485514b90e7a9
60 N2c771e60a15b4db8ad490ed107cad152 rdf:first sg:person.07773620344.16
61 rdf:rest N09ed100654f24b219e610207bafa1e83
62 N38193abed3734a7c982891e4673cb1c0 schema:name School of Doctoral Studies and Research, Universidad Europea, Calle Tajo, s/n, Villaviciosa de Odón, 28670, Madrid, Spain
63 rdf:type schema:Organization
64 N3d676e02f78c4e9692e1fbb5102f2971 rdf:first sg:person.015237435431.63
65 rdf:rest N80064d148a1342f9a9dcbfc05815e8ce
66 N48266d14f97546499ab46d89dfba57d5 schema:affiliation https://www.grid.ac/institutes/grid.488466.0
67 schema:familyName Varela
68 schema:givenName A.
69 rdf:type schema:Person
70 N539b182740904cd6810bae3edad83f56 schema:name Springer Nature - SN SciGraph project
71 rdf:type schema:Organization
72 N5592baf53a174f41abe8ec414733015f rdf:first sg:person.01112500207.75
73 rdf:rest N573ec16696e94ff8b04b15fa70a14c50
74 N573ec16696e94ff8b04b15fa70a14c50 rdf:first sg:person.07730255311.20
75 rdf:rest N76416fa025be46f0b73c0b48adb13f13
76 N5a3e36a7b6954488897c9e1ee8f07f34 rdf:first Ncf1718b0c3004cc8adf343b70bbaa1c5
77 rdf:rest Nc463627ca3f34c709c7fdbe835e9b46a
78 N5c92ce92ddac40b790e38819efb6aec8 rdf:first sg:person.01041420505.74
79 rdf:rest N20d8148a1a7f44bab3bfab154c7196ec
80 N5d5a08fdfe8e4ed48214eecd54167fd9 rdf:first sg:person.01060676471.47
81 rdf:rest N8287f0ebd8784961b7a9d8652aba1296
82 N73ac4693e1b34d96ac9665794f587ad9 rdf:first sg:person.016547657361.10
83 rdf:rest Ne0bb48bbca224a7cbf254befa05867c0
84 N76416fa025be46f0b73c0b48adb13f13 rdf:first sg:person.010450543003.13
85 rdf:rest N73ac4693e1b34d96ac9665794f587ad9
86 N7fc86c0d31c84ca1be1a62f1ffca8218 rdf:first sg:person.01066464116.22
87 rdf:rest Nf0eb46877aed449eb1c73a9d7521ed23
88 N80064d148a1342f9a9dcbfc05815e8ce rdf:first sg:person.0657022205.16
89 rdf:rest N5d5a08fdfe8e4ed48214eecd54167fd9
90 N8287f0ebd8784961b7a9d8652aba1296 rdf:first sg:person.07354663610.23
91 rdf:rest Naeb31567886c41b48bec64a110a06f39
92 Na40faa4e54974fd29265b3eeff39827d schema:name nlm_unique_id
93 schema:value 101247119
94 rdf:type schema:PropertyValue
95 Naa3c76d10e3f498dbf7ffd63dc6fd2c3 schema:name pubmed_id
96 schema:value 30430394
97 rdf:type schema:PropertyValue
98 Naeb31567886c41b48bec64a110a06f39 rdf:first sg:person.013260312544.60
99 rdf:rest N5a3e36a7b6954488897c9e1ee8f07f34
100 Naebce225e6a54d169a98af734298f09f rdf:first sg:person.011276764371.60
101 rdf:rest N5c92ce92ddac40b790e38819efb6aec8
102 Nb40afce271fd4d58b715e7f43fcf3091 schema:name Department of Radiation Oncology, Complexo Hospitalario Universitario Santiago de Compostela, Choupana s/n, bloque d. Santiago de Compostela, A Coruña, Spain
103 rdf:type schema:Organization
104 Nc463627ca3f34c709c7fdbe835e9b46a rdf:first sg:person.010007651524.18
105 rdf:rest N7fc86c0d31c84ca1be1a62f1ffca8218
106 Ncd074e8bfbe948fb8fe85d2f75539980 schema:name readcube_id
107 schema:value f36020049590105892062f9ce2c27869e81778cf0682c3dd9b6d308fcb317b89
108 rdf:type schema:PropertyValue
109 Ncf1718b0c3004cc8adf343b70bbaa1c5 schema:affiliation https://www.grid.ac/institutes/grid.418082.7
110 schema:familyName Chust
111 schema:givenName M.
112 rdf:type schema:Person
113 Ndddcfcef57444730b286a393fac257c2 rdf:first N48266d14f97546499ab46d89dfba57d5
114 rdf:rest N2c771e60a15b4db8ad490ed107cad152
115 Ndf87b0a522ae4d6eaec7fe372bb39016 schema:name Department of Radiation Oncology, Complexo Hospitalario Universitario Santiago de Compostela, Choupana s/n, bloque d. Santiago de Compostela, A Coruña, Spain
116 rdf:type schema:Organization
117 Ne0bb48bbca224a7cbf254befa05867c0 rdf:first sg:person.01333721120.97
118 rdf:rest N09249b755ebc49c9af8f0e6f717b4d82
119 Ne2511d865ac743349228a8a33823de4e rdf:first sg:person.016154203151.10
120 rdf:rest rdf:nil
121 Nead2e4fbe0a746cbb000d6dc46a19309 schema:name doi
122 schema:value 10.1007/s12094-018-1976-3
123 rdf:type schema:PropertyValue
124 Nf0b40e6dc8c04412badb2ad600bdd0b8 rdf:first sg:person.01106152460.14
125 rdf:rest N3d676e02f78c4e9692e1fbb5102f2971
126 Nf0eb46877aed449eb1c73a9d7521ed23 rdf:first sg:person.016512722724.26
127 rdf:rest Naebce225e6a54d169a98af734298f09f
128 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
129 schema:name Medical and Health Sciences
130 rdf:type schema:DefinedTerm
131 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
132 schema:name Oncology and Carcinogenesis
133 rdf:type schema:DefinedTerm
134 sg:journal.1035367 schema:issn 1699-048X
135 1699-3055
136 schema:name Clinical and Translational Oncology
137 rdf:type schema:Periodical
138 sg:person.010007651524.18 schema:affiliation https://www.grid.ac/institutes/grid.411342.1
139 schema:familyName Díaz-Díaz
140 schema:givenName V.
141 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010007651524.18
142 rdf:type schema:Person
143 sg:person.01002112707.49 schema:affiliation N1135177346d848e7aabdd5874d2727c2
144 schema:familyName Thuissard
145 schema:givenName I. J.
146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002112707.49
147 rdf:type schema:Person
148 sg:person.01041420505.74 schema:affiliation https://www.grid.ac/institutes/grid.119375.8
149 schema:familyName del Cerro
150 schema:givenName E.
151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041420505.74
152 rdf:type schema:Person
153 sg:person.010450543003.13 schema:affiliation https://www.grid.ac/institutes/grid.411347.4
154 schema:familyName Martin
155 schema:givenName M.
156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010450543003.13
157 rdf:type schema:Person
158 sg:person.01060676471.47 schema:affiliation https://www.grid.ac/institutes/grid.411136.0
159 schema:familyName Murcia-Mejía
160 schema:givenName M.
161 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060676471.47
162 rdf:type schema:Person
163 sg:person.01066464116.22 schema:affiliation https://www.grid.ac/institutes/grid.411342.1
164 schema:familyName de Ingunza-Barón
165 schema:givenName L.
166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066464116.22
167 rdf:type schema:Person
168 sg:person.01106152460.14 schema:affiliation https://www.grid.ac/institutes/grid.411068.a
169 schema:familyName Alcántara
170 schema:givenName P.
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01106152460.14
172 rdf:type schema:Person
173 sg:person.01112500207.75 schema:affiliation https://www.grid.ac/institutes/grid.119375.8
174 schema:familyName Couñago
175 schema:givenName F.
176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112500207.75
177 rdf:type schema:Person
178 sg:person.011276764371.60 schema:affiliation https://www.grid.ac/institutes/grid.414398.3
179 schema:familyName Couselo
180 schema:givenName M. L.
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011276764371.60
182 rdf:type schema:Person
183 sg:person.01157215035.22 schema:affiliation N38193abed3734a7c982891e4673cb1c0
184 schema:familyName Sanz-Rosa
185 schema:givenName D.
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157215035.22
187 rdf:type schema:Person
188 sg:person.013260312544.60 schema:affiliation https://www.grid.ac/institutes/grid.411438.b
189 schema:familyName Jové-Teixidó
190 schema:givenName J.
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013260312544.60
192 rdf:type schema:Person
193 sg:person.01333721120.97 schema:affiliation Ndf87b0a522ae4d6eaec7fe372bb39016
194 schema:familyName Calvo-Crespo
195 schema:givenName P.
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333721120.97
197 rdf:type schema:Person
198 sg:person.013663552310.50 schema:affiliation https://www.grid.ac/institutes/grid.459654.f
199 schema:familyName Samper-Ots
200 schema:givenName M. P.
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013663552310.50
202 rdf:type schema:Person
203 sg:person.015237435431.63 schema:affiliation https://www.grid.ac/institutes/grid.411068.a
204 schema:familyName Corona
205 schema:givenName J.
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015237435431.63
207 rdf:type schema:Person
208 sg:person.015503443363.37 schema:affiliation https://www.grid.ac/institutes/grid.488466.0
209 schema:familyName Amor
210 schema:givenName S.
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015503443363.37
212 rdf:type schema:Person
213 sg:person.016154203151.10 schema:affiliation https://www.grid.ac/institutes/grid.411142.3
214 schema:familyName de Dios
215 schema:givenName N. R.
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016154203151.10
217 rdf:type schema:Person
218 sg:person.016512722724.26 schema:affiliation https://www.grid.ac/institutes/grid.411242.0
219 schema:familyName García-Cañibano
220 schema:givenName T.
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016512722724.26
222 rdf:type schema:Person
223 sg:person.016547657361.10 schema:affiliation Nb40afce271fd4d58b715e7f43fcf3091
224 schema:familyName Taboada
225 schema:givenName B.
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016547657361.10
227 rdf:type schema:Person
228 sg:person.0604703213.28 schema:affiliation https://www.grid.ac/institutes/grid.488466.0
229 schema:familyName Moradiellos
230 schema:givenName J.
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604703213.28
232 rdf:type schema:Person
233 sg:person.0657022205.16 schema:affiliation https://www.grid.ac/institutes/grid.411109.c
234 schema:familyName López-Guerra
235 schema:givenName J. L.
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657022205.16
237 rdf:type schema:Person
238 sg:person.07354663610.23 schema:affiliation https://www.grid.ac/institutes/grid.411050.1
239 schema:familyName López-Mata
240 schema:givenName M.
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07354663610.23
242 rdf:type schema:Person
243 sg:person.07730255311.20 schema:affiliation https://www.grid.ac/institutes/grid.411242.0
244 schema:familyName Montemuiño
245 schema:givenName S.
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07730255311.20
247 rdf:type schema:Person
248 sg:person.07773620344.16 schema:affiliation https://www.grid.ac/institutes/grid.411106.3
249 schema:familyName Puertas
250 schema:givenName M. M.
251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07773620344.16
252 rdf:type schema:Person
253 https://doi.org/10.1002/14651858.cd002140.pub3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046701409
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1002/cncr.26689 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035566227
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/j.athoracsur.2008.04.073 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036068306
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1016/j.jtho.2016.09.122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003691650
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1016/j.lungcan.2016.03.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033878468
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1016/s0039-6109(16)44341-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042606273
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1016/s0140-6736(09)60737-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004597708
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1093/annonc/mdu348.1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083557079
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1093/ejcts/ezu504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059551104
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1093/ejcts/ezv431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059551486
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1093/ejcts/ezw040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059551579
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1093/icvts/ivu141 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021460342
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1093/jnci/djk093 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019816459
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1177/107327481402100108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078830666
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1200/jco.2009.26.2543 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039864167
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1200/jco.2015.62.6812 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036512173
284 rdf:type schema:CreativeWork
285 https://doi.org/10.2147/ott.s95511 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009276381
286 rdf:type schema:CreativeWork
287 https://doi.org/10.6004/jnccn.2017.0050 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084819289
288 rdf:type schema:CreativeWork
289 https://www.grid.ac/institutes/grid.119375.8 schema:alternateName European University of Madrid
290 schema:name Department of Radiation Oncology, Hospital Universitario Quirónsalud Madrid, C/ Diego de Velázquez1, 1, Pozuelo de Alarcón, 28223, Madrid, Spain
291 Universidad Europea de Madrid, Calle Tajo, s/n, Villaviciosa de Odón, 28670, Madrid, Spain
292 rdf:type schema:Organization
293 https://www.grid.ac/institutes/grid.411050.1 schema:alternateName Hospital Clínico Universitario Lozano Blesa
294 schema:name Department of Radiation Oncology, Hospital Clinico Universitario Lozano Blesa, San Juan Bosco 15, Zaragoza, Spain
295 rdf:type schema:Organization
296 https://www.grid.ac/institutes/grid.411068.a schema:alternateName Hospital Clínico San Carlos
297 schema:name Department of Radiation Oncology, Hospital Universitario Clínico San Carlos, C/Prof, Martín Lagos s/n, Madrid, Spain
298 rdf:type schema:Organization
299 https://www.grid.ac/institutes/grid.411106.3 schema:alternateName Hospital Universitario Miguel Servet
300 schema:name Department of Radiation Oncology, Hospital Universitario Miguel Servet, Paseo Isabel la Católica, 1-3, 50009, Zaragoza, Spain
301 rdf:type schema:Organization
302 https://www.grid.ac/institutes/grid.411109.c schema:alternateName Hospital Universitario Virgen del Rocío
303 schema:name Department of Radiation Oncology, Hospital Universitario Virgen del Rocio, Av. Manuel Siurot, S/N, 41013, Seville, Spain
304 rdf:type schema:Organization
305 https://www.grid.ac/institutes/grid.411136.0 schema:alternateName Hospital Universitari Sant Joan de Reus
306 schema:name Department of Radiation Oncology, Hospital Universitari Sant Joan de Reus, Av. del Dr. Josep Laporte, 2, 43204, Reus, Tarragona, Spain
307 rdf:type schema:Organization
308 https://www.grid.ac/institutes/grid.411142.3 schema:alternateName Hospital Del Mar
309 schema:name Department of Radiation Oncology, Hospital del Mar. Passeig Marítim, 25-29, 08003, Barcelona, Spain
310 IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain
311 rdf:type schema:Organization
312 https://www.grid.ac/institutes/grid.411242.0 schema:alternateName Hospital Universitario de Fuenlabrada
313 schema:name Department of Radiation Oncology, Hospital Universitario de Fuenlabrada, Camino del Molino, 2, 28942, Fuenlabrada, Madrid, Spain
314 rdf:type schema:Organization
315 https://www.grid.ac/institutes/grid.411342.1 schema:alternateName Hospital Universitario Puerta del Mar
316 schema:name Department of Radiation Oncology, Hospital Universitario Puerta del Mar, Av. Ana de Viya, 21, 11009, Cadiz, Spain
317 rdf:type schema:Organization
318 https://www.grid.ac/institutes/grid.411347.4 schema:alternateName Hospital Universitario Ramón y Cajal
319 schema:name Department of Radiation Oncology, Hospital Universitario Ramon y Cajal, Carretera de Colmenar Viejo Km9, Madrid, Spain
320 rdf:type schema:Organization
321 https://www.grid.ac/institutes/grid.411438.b schema:alternateName Hospital Universitari Germans Trias i Pujol
322 schema:name Department of Radiation Oncology, Hospital Germans Trias i Pujol, Carretera de Canyet, s/n, 08916, Badalona, Spain
323 rdf:type schema:Organization
324 https://www.grid.ac/institutes/grid.414398.3 schema:alternateName Hospital Central de la Defensa Gómez Ulla
325 schema:name Department of Radiation Oncology, Hospital Central de la Defensa Gomez Ulla, Glorieta Ejército, 1, 28047, Madrid, Spain
326 rdf:type schema:Organization
327 https://www.grid.ac/institutes/grid.418082.7 schema:alternateName Fundación Instituto Valenciano de Oncología
328 schema:name Department of Radiation Oncology, Instituto Valenciano de Oncologia, Carrer del Professor Beltrán Báguena, 8, 46009, Valencia, Spain
329 rdf:type schema:Organization
330 https://www.grid.ac/institutes/grid.459654.f schema:alternateName Hospital Universitario Rey Juan Carlos
331 schema:name Department of Radiation Oncology, Hospital Universitario Rey Juan Carlos, C/Gladiolo s/n. Móstoles, Madrid, Spain
332 rdf:type schema:Organization
333 https://www.grid.ac/institutes/grid.488466.0 schema:alternateName Hospital Universitario Quirónsalud Madrid
334 schema:name Department of Thoracic Surgery, Hospital Universitario Quirónsalud Madrid, C/Diego de Velázquez, 1, Pozuelo de Alarcón, 28223, Madrid, Spain
335 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...