Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-10-03

AUTHORS

C. Grávalos, O. Sanmartín, A. Gúrpide, A. España, M. Majem, H. J. Suh Oh, I. Aragón, S. Segura, C. Beato, R. Botella

ABSTRACT

Progress in the understanding of many tumors has enabled the development of new therapies, such as those targeted at specific molecules involved in cell growth (targeted therapies) or intended to modulate the immune system (immunotherapy). However, along with the clinical benefit provided by these new treatments, new adverse effects have also appeared. Dermatological toxicities such as papulopustular eruptions, xerosis, and pruritus are common with EGFR inhibitors. Other adverse effects have also been described with PDGFR, BCR-ABL, and MAPK tyrosine kinase inhibitors, antiangiogenic drugs, and inhibitors at immune checkpoints such as CTLA-4 and PD-1/PD-L1. Onset of these adverse effects often causes dose reductions and/or delays in administering the prescribed therapy, which can affect patient survival and quality of life. It is, therefore, important to prevent the occurrence of these adverse effects, or to treat unavoidable ones as soon as possible. This requires cooperation between medical oncologists and dermatologists. This article reviews the various dermatological toxicities associated with targeted therapies and immunotherapies, along with their diagnosis and therapeutic management. More... »

PAGES

556-571

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12094-018-1953-x

DOI

http://dx.doi.org/10.1007/s12094-018-1953-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1107372607

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30284232


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Cardiorespiratory Medicine and Haematology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antineoplastic Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Consensus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dermatology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Management", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunotherapy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Targeted Therapy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Quality of Life", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Skin Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Societies, Medical", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Venereology", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Medical Oncology Department, Hospital Universitario 12 de Octubre, Avenida de C\u00f3rdoba km 5.4, 28041, Madrid, Spain", 
          "id": "http://www.grid.ac/institutes/grid.144756.5", 
          "name": [
            "Medical Oncology Department, Hospital Universitario 12 de Octubre, Avenida de C\u00f3rdoba km 5.4, 28041, Madrid, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gr\u00e1valos", 
        "givenName": "C.", 
        "id": "sg:person.01154240231.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154240231.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Dermatology Department, Instituto Valenciano de Oncolog\u00eda, Valencia, Spain", 
          "id": "http://www.grid.ac/institutes/grid.418082.7", 
          "name": [
            "Dermatology Department, Instituto Valenciano de Oncolog\u00eda, Valencia, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sanmart\u00edn", 
        "givenName": "O.", 
        "id": "sg:person.01366510222.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366510222.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medical Oncology Department, Cl\u00ednica Universitaria de Navarra, Pamplona, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411730.0", 
          "name": [
            "Medical Oncology Department, Cl\u00ednica Universitaria de Navarra, Pamplona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "G\u00farpide", 
        "givenName": "A.", 
        "id": "sg:person.01217610022.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01217610022.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Dermatology Department, Cl\u00ednica Universitaria de Navarra, Pamplona, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411730.0", 
          "name": [
            "Dermatology Department, Cl\u00ednica Universitaria de Navarra, Pamplona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Espa\u00f1a", 
        "givenName": "A.", 
        "id": "sg:person.01331023202.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331023202.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain", 
          "id": "http://www.grid.ac/institutes/grid.413396.a", 
          "name": [
            "Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Majem", 
        "givenName": "M.", 
        "id": "sg:person.01322640302.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322640302.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Dermatology Department, Complejo Hospitalario Universitario de Pontevedra, Pontevedra, Spain", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Dermatology Department, Complejo Hospitalario Universitario de Pontevedra, Pontevedra, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Suh Oh", 
        "givenName": "H. J.", 
        "id": "sg:person.01260762272.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260762272.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medical Oncology Department, Complejo Hospitalario Universitario de Huelva, Huelva, Spain", 
          "id": "http://www.grid.ac/institutes/grid.18803.32", 
          "name": [
            "Medical Oncology Department, Complejo Hospitalario Universitario de Huelva, Huelva, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Arag\u00f3n", 
        "givenName": "I.", 
        "id": "sg:person.016112431265.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016112431265.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Dermatology Department, Hospital del Mar, Barcelona, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411142.3", 
          "name": [
            "Dermatology Department, Hospital del Mar, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Segura", 
        "givenName": "S.", 
        "id": "sg:person.01002260605.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002260605.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Medical Oncology Department, Hospital Universitario Virgen Macarena, Sevilla, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411375.5", 
          "name": [
            "Medical Oncology Department, Hospital Universitario Virgen Macarena, Sevilla, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Beato", 
        "givenName": "C.", 
        "id": "sg:person.0675231766.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675231766.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Dermatology Service, Instituto de Investigaci\u00f3n Sanitaria La Fe, Valencia, Spain", 
          "id": "http://www.grid.ac/institutes/grid.476458.c", 
          "name": [
            "Dermatology Service, Instituto de Investigaci\u00f3n Sanitaria La Fe, Valencia, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Botella", 
        "givenName": "R.", 
        "id": "sg:person.01136232206.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01136232206.44"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00520-011-1197-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038538227", 
          "https://doi.org/10.1007/s00520-011-1197-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00520-008-0409-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012623957", 
          "https://doi.org/10.1007/s00520-008-0409-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00520-013-2085-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004735391", 
          "https://doi.org/10.1007/s00520-013-2085-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11523-009-0107-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032919247", 
          "https://doi.org/10.1007/s11523-009-0107-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11864-015-0368-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043321307", 
          "https://doi.org/10.1007/s11864-015-0368-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s40257-014-0088-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042465780", 
          "https://doi.org/10.1007/s40257-014-0088-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11523-009-0114-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000094783", 
          "https://doi.org/10.1007/s11523-009-0114-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s40257-016-0197-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046772547", 
          "https://doi.org/10.1007/s40257-016-0197-1"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-10-03", 
    "datePublishedReg": "2018-10-03", 
    "description": "Progress in the understanding of many tumors has enabled the development of new therapies, such as those targeted at specific molecules involved in cell growth (targeted therapies) or intended to modulate the immune system (immunotherapy). However, along with the clinical benefit provided by these new treatments, new adverse effects have also appeared. Dermatological toxicities such as papulopustular eruptions, xerosis, and pruritus are common with EGFR inhibitors. Other adverse effects have also been described with PDGFR, BCR-ABL, and MAPK tyrosine kinase inhibitors, antiangiogenic drugs, and inhibitors at immune checkpoints such as CTLA-4 and PD-1/PD-L1. Onset of these adverse effects often causes dose reductions and/or delays in administering the prescribed therapy, which can affect patient survival and quality of life. It is, therefore, important to prevent the occurrence of these adverse effects, or to treat unavoidable ones as soon as possible. This requires cooperation between medical oncologists and dermatologists. This article reviews the various dermatological toxicities associated with targeted therapies and immunotherapies, along with their diagnosis and therapeutic management.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s12094-018-1953-x", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1035367", 
        "issn": [
          "1699-048X", 
          "1699-3055"
        ], 
        "name": "Clinical and Translational Oncology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "21"
      }
    ], 
    "keywords": [
      "adverse effects", 
      "dermatological toxicities", 
      "PD-1/PD-L1", 
      "cutaneous adverse events", 
      "PD-L1", 
      "new adverse effects", 
      "national consensus statement", 
      "quality of life", 
      "tyrosine kinase inhibitors", 
      "BCR-ABL", 
      "papulopustular eruption", 
      "immune checkpoints", 
      "adverse events", 
      "medical oncologists", 
      "prescribed therapy", 
      "patient survival", 
      "clinical benefit", 
      "therapeutic management", 
      "medical oncology", 
      "clinical management", 
      "antiangiogenic drugs", 
      "dose reduction", 
      "consensus statement", 
      "new therapies", 
      "immune system", 
      "new treatments", 
      "therapy", 
      "EGFR inhibitors", 
      "anticancer therapy", 
      "kinase inhibitors", 
      "immunotherapy", 
      "Spanish Society", 
      "inhibitors", 
      "cell growth", 
      "toxicity", 
      "pruritus", 
      "CTLA-4", 
      "patients", 
      "oncologists", 
      "Spanish Academy", 
      "Venereology", 
      "specific molecules", 
      "xerosis", 
      "tumors", 
      "dermatologists", 
      "diagnosis", 
      "oncology", 
      "PDGFR", 
      "drugs", 
      "dermatology", 
      "management", 
      "survival", 
      "effect", 
      "treatment", 
      "onset", 
      "life", 
      "benefits", 
      "occurrence", 
      "reduction", 
      "events", 
      "unavoidable ones", 
      "eruption", 
      "checkpoint", 
      "development", 
      "Academy", 
      "quality", 
      "delay", 
      "progress", 
      "understanding", 
      "growth", 
      "molecules", 
      "statements", 
      "article", 
      "society", 
      "system", 
      "one", 
      "cooperation", 
      "MAPK tyrosine kinase inhibitors"
    ], 
    "name": "Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology", 
    "pagination": "556-571", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1107372607"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12094-018-1953-x"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30284232"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12094-018-1953-x", 
      "https://app.dimensions.ai/details/publication/pub.1107372607"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-11-01T18:34", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_789.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s12094-018-1953-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12094-018-1953-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12094-018-1953-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12094-018-1953-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12094-018-1953-x'


 

This table displays all metadata directly associated to this object as RDF triples.

309 TRIPLES      22 PREDICATES      123 URIs      107 LITERALS      19 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12094-018-1953-x schema:about N00347bcd61004081a1243fd5d44d6df4
2 N220f68e46a0c44ab978b30423315efde
3 N3866f61f5bf64f1a9211abb365057b06
4 N425d5c56629f4c309c686d1b3256b80e
5 N8febafc2434641bba7bc9183cfcffe16
6 Na90d10b92dad41cfb5bc002b3c4ce2cd
7 Nceee0aa9800f430cb969ff6da61d347c
8 Ndb1412d663264b23832f3b8bee37e0a3
9 Ne3439de9f9b7405c835827bca6c75269
10 Nf053ff8a44a04a47919789a48b1952d4
11 Nf537e915fe964f5cbdcc0668c3914e06
12 Nf78e748a02894594ae577af23c6d3f5c
13 anzsrc-for:11
14 anzsrc-for:1102
15 schema:author N9acf765fa3a9470da3918e595d3b2ad1
16 schema:citation sg:pub.10.1007/s00520-008-0409-1
17 sg:pub.10.1007/s00520-011-1197-6
18 sg:pub.10.1007/s00520-013-2085-z
19 sg:pub.10.1007/s11523-009-0107-z
20 sg:pub.10.1007/s11523-009-0114-0
21 sg:pub.10.1007/s11864-015-0368-y
22 sg:pub.10.1007/s40257-014-0088-2
23 sg:pub.10.1007/s40257-016-0197-1
24 schema:datePublished 2018-10-03
25 schema:datePublishedReg 2018-10-03
26 schema:description Progress in the understanding of many tumors has enabled the development of new therapies, such as those targeted at specific molecules involved in cell growth (targeted therapies) or intended to modulate the immune system (immunotherapy). However, along with the clinical benefit provided by these new treatments, new adverse effects have also appeared. Dermatological toxicities such as papulopustular eruptions, xerosis, and pruritus are common with EGFR inhibitors. Other adverse effects have also been described with PDGFR, BCR-ABL, and MAPK tyrosine kinase inhibitors, antiangiogenic drugs, and inhibitors at immune checkpoints such as CTLA-4 and PD-1/PD-L1. Onset of these adverse effects often causes dose reductions and/or delays in administering the prescribed therapy, which can affect patient survival and quality of life. It is, therefore, important to prevent the occurrence of these adverse effects, or to treat unavoidable ones as soon as possible. This requires cooperation between medical oncologists and dermatologists. This article reviews the various dermatological toxicities associated with targeted therapies and immunotherapies, along with their diagnosis and therapeutic management.
27 schema:genre article
28 schema:inLanguage en
29 schema:isAccessibleForFree true
30 schema:isPartOf Nd926c8df8a8a4882a066b405a4bb66f6
31 Nee227493625543f1919647e2e93a1ecf
32 sg:journal.1035367
33 schema:keywords Academy
34 BCR-ABL
35 CTLA-4
36 EGFR inhibitors
37 MAPK tyrosine kinase inhibitors
38 PD-1/PD-L1
39 PD-L1
40 PDGFR
41 Spanish Academy
42 Spanish Society
43 Venereology
44 adverse effects
45 adverse events
46 antiangiogenic drugs
47 anticancer therapy
48 article
49 benefits
50 cell growth
51 checkpoint
52 clinical benefit
53 clinical management
54 consensus statement
55 cooperation
56 cutaneous adverse events
57 delay
58 dermatological toxicities
59 dermatologists
60 dermatology
61 development
62 diagnosis
63 dose reduction
64 drugs
65 effect
66 eruption
67 events
68 growth
69 immune checkpoints
70 immune system
71 immunotherapy
72 inhibitors
73 kinase inhibitors
74 life
75 management
76 medical oncologists
77 medical oncology
78 molecules
79 national consensus statement
80 new adverse effects
81 new therapies
82 new treatments
83 occurrence
84 oncologists
85 oncology
86 one
87 onset
88 papulopustular eruption
89 patient survival
90 patients
91 prescribed therapy
92 progress
93 pruritus
94 quality
95 quality of life
96 reduction
97 society
98 specific molecules
99 statements
100 survival
101 system
102 therapeutic management
103 therapy
104 toxicity
105 treatment
106 tumors
107 tyrosine kinase inhibitors
108 unavoidable ones
109 understanding
110 xerosis
111 schema:name Clinical management of cutaneous adverse events in patients on targeted anticancer therapies and immunotherapies: a national consensus statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology
112 schema:pagination 556-571
113 schema:productId N1fa2e72b284d4b90bf17a042789ef04b
114 Naa9a5e4e6d4b4e3b9531d0e6e1ade552
115 Nea24729a20b849498bab3bcb1418ecab
116 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107372607
117 https://doi.org/10.1007/s12094-018-1953-x
118 schema:sdDatePublished 2021-11-01T18:34
119 schema:sdLicense https://scigraph.springernature.com/explorer/license/
120 schema:sdPublisher N8444f773dfc14cfcbdc5c19c3e42cc74
121 schema:url https://doi.org/10.1007/s12094-018-1953-x
122 sgo:license sg:explorer/license/
123 sgo:sdDataset articles
124 rdf:type schema:ScholarlyArticle
125 N00347bcd61004081a1243fd5d44d6df4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Consensus
127 rdf:type schema:DefinedTerm
128 N1fa2e72b284d4b90bf17a042789ef04b schema:name pubmed_id
129 schema:value 30284232
130 rdf:type schema:PropertyValue
131 N220f68e46a0c44ab978b30423315efde schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Immunotherapy
133 rdf:type schema:DefinedTerm
134 N30d4b977e37441b0b3491cafc53353d5 rdf:first sg:person.01002260605.28
135 rdf:rest N39d03110632b4f15ac8f570d8c425f1a
136 N3866f61f5bf64f1a9211abb365057b06 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Societies, Medical
138 rdf:type schema:DefinedTerm
139 N39d03110632b4f15ac8f570d8c425f1a rdf:first sg:person.0675231766.90
140 rdf:rest Ncd53bc1acd414b1cb0d4f81c3845d914
141 N41db5d34830445d0b9eb8090a16495c1 rdf:first sg:person.01322640302.82
142 rdf:rest Nfc108db34bed4e508e01af158f85591d
143 N425d5c56629f4c309c686d1b3256b80e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Neoplasms
145 rdf:type schema:DefinedTerm
146 N498feb5c040e4fbeb464a01d23119285 rdf:first sg:person.016112431265.39
147 rdf:rest N30d4b977e37441b0b3491cafc53353d5
148 N75673ba635c0463d853ff608068d4d9e rdf:first sg:person.01331023202.82
149 rdf:rest N41db5d34830445d0b9eb8090a16495c1
150 N8444f773dfc14cfcbdc5c19c3e42cc74 schema:name Springer Nature - SN SciGraph project
151 rdf:type schema:Organization
152 N8d24dca2c05e4a0ea48c632c6b06ca93 rdf:first sg:person.01217610022.22
153 rdf:rest N75673ba635c0463d853ff608068d4d9e
154 N8febafc2434641bba7bc9183cfcffe16 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Quality of Life
156 rdf:type schema:DefinedTerm
157 N9acf765fa3a9470da3918e595d3b2ad1 rdf:first sg:person.01154240231.01
158 rdf:rest Nfc96509f10e24759b93126dad63bcdcb
159 Na90d10b92dad41cfb5bc002b3c4ce2cd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Dermatology
161 rdf:type schema:DefinedTerm
162 Naa9a5e4e6d4b4e3b9531d0e6e1ade552 schema:name dimensions_id
163 schema:value pub.1107372607
164 rdf:type schema:PropertyValue
165 Ncd53bc1acd414b1cb0d4f81c3845d914 rdf:first sg:person.01136232206.44
166 rdf:rest rdf:nil
167 Nceee0aa9800f430cb969ff6da61d347c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Humans
169 rdf:type schema:DefinedTerm
170 Nd926c8df8a8a4882a066b405a4bb66f6 schema:issueNumber 5
171 rdf:type schema:PublicationIssue
172 Ndb1412d663264b23832f3b8bee37e0a3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Antineoplastic Agents
174 rdf:type schema:DefinedTerm
175 Ne3439de9f9b7405c835827bca6c75269 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
176 schema:name Molecular Targeted Therapy
177 rdf:type schema:DefinedTerm
178 Nea24729a20b849498bab3bcb1418ecab schema:name doi
179 schema:value 10.1007/s12094-018-1953-x
180 rdf:type schema:PropertyValue
181 Nee227493625543f1919647e2e93a1ecf schema:volumeNumber 21
182 rdf:type schema:PublicationVolume
183 Nf053ff8a44a04a47919789a48b1952d4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
184 schema:name Skin Diseases
185 rdf:type schema:DefinedTerm
186 Nf537e915fe964f5cbdcc0668c3914e06 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Venereology
188 rdf:type schema:DefinedTerm
189 Nf78e748a02894594ae577af23c6d3f5c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
190 schema:name Disease Management
191 rdf:type schema:DefinedTerm
192 Nfc108db34bed4e508e01af158f85591d rdf:first sg:person.01260762272.26
193 rdf:rest N498feb5c040e4fbeb464a01d23119285
194 Nfc96509f10e24759b93126dad63bcdcb rdf:first sg:person.01366510222.37
195 rdf:rest N8d24dca2c05e4a0ea48c632c6b06ca93
196 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
197 schema:name Medical and Health Sciences
198 rdf:type schema:DefinedTerm
199 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
200 schema:name Cardiorespiratory Medicine and Haematology
201 rdf:type schema:DefinedTerm
202 sg:journal.1035367 schema:issn 1699-048X
203 1699-3055
204 schema:name Clinical and Translational Oncology
205 schema:publisher Springer Nature
206 rdf:type schema:Periodical
207 sg:person.01002260605.28 schema:affiliation grid-institutes:grid.411142.3
208 schema:familyName Segura
209 schema:givenName S.
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002260605.28
211 rdf:type schema:Person
212 sg:person.01136232206.44 schema:affiliation grid-institutes:grid.476458.c
213 schema:familyName Botella
214 schema:givenName R.
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01136232206.44
216 rdf:type schema:Person
217 sg:person.01154240231.01 schema:affiliation grid-institutes:grid.144756.5
218 schema:familyName Grávalos
219 schema:givenName C.
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154240231.01
221 rdf:type schema:Person
222 sg:person.01217610022.22 schema:affiliation grid-institutes:grid.411730.0
223 schema:familyName Gúrpide
224 schema:givenName A.
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01217610022.22
226 rdf:type schema:Person
227 sg:person.01260762272.26 schema:affiliation grid-institutes:None
228 schema:familyName Suh Oh
229 schema:givenName H. J.
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260762272.26
231 rdf:type schema:Person
232 sg:person.01322640302.82 schema:affiliation grid-institutes:grid.413396.a
233 schema:familyName Majem
234 schema:givenName M.
235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322640302.82
236 rdf:type schema:Person
237 sg:person.01331023202.82 schema:affiliation grid-institutes:grid.411730.0
238 schema:familyName España
239 schema:givenName A.
240 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331023202.82
241 rdf:type schema:Person
242 sg:person.01366510222.37 schema:affiliation grid-institutes:grid.418082.7
243 schema:familyName Sanmartín
244 schema:givenName O.
245 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366510222.37
246 rdf:type schema:Person
247 sg:person.016112431265.39 schema:affiliation grid-institutes:grid.18803.32
248 schema:familyName Aragón
249 schema:givenName I.
250 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016112431265.39
251 rdf:type schema:Person
252 sg:person.0675231766.90 schema:affiliation grid-institutes:grid.411375.5
253 schema:familyName Beato
254 schema:givenName C.
255 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675231766.90
256 rdf:type schema:Person
257 sg:pub.10.1007/s00520-008-0409-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012623957
258 https://doi.org/10.1007/s00520-008-0409-1
259 rdf:type schema:CreativeWork
260 sg:pub.10.1007/s00520-011-1197-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038538227
261 https://doi.org/10.1007/s00520-011-1197-6
262 rdf:type schema:CreativeWork
263 sg:pub.10.1007/s00520-013-2085-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1004735391
264 https://doi.org/10.1007/s00520-013-2085-z
265 rdf:type schema:CreativeWork
266 sg:pub.10.1007/s11523-009-0107-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1032919247
267 https://doi.org/10.1007/s11523-009-0107-z
268 rdf:type schema:CreativeWork
269 sg:pub.10.1007/s11523-009-0114-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000094783
270 https://doi.org/10.1007/s11523-009-0114-0
271 rdf:type schema:CreativeWork
272 sg:pub.10.1007/s11864-015-0368-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1043321307
273 https://doi.org/10.1007/s11864-015-0368-y
274 rdf:type schema:CreativeWork
275 sg:pub.10.1007/s40257-014-0088-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042465780
276 https://doi.org/10.1007/s40257-014-0088-2
277 rdf:type schema:CreativeWork
278 sg:pub.10.1007/s40257-016-0197-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046772547
279 https://doi.org/10.1007/s40257-016-0197-1
280 rdf:type schema:CreativeWork
281 grid-institutes:None schema:alternateName Dermatology Department, Complejo Hospitalario Universitario de Pontevedra, Pontevedra, Spain
282 schema:name Dermatology Department, Complejo Hospitalario Universitario de Pontevedra, Pontevedra, Spain
283 rdf:type schema:Organization
284 grid-institutes:grid.144756.5 schema:alternateName Medical Oncology Department, Hospital Universitario 12 de Octubre, Avenida de Córdoba km 5.4, 28041, Madrid, Spain
285 schema:name Medical Oncology Department, Hospital Universitario 12 de Octubre, Avenida de Córdoba km 5.4, 28041, Madrid, Spain
286 rdf:type schema:Organization
287 grid-institutes:grid.18803.32 schema:alternateName Medical Oncology Department, Complejo Hospitalario Universitario de Huelva, Huelva, Spain
288 schema:name Medical Oncology Department, Complejo Hospitalario Universitario de Huelva, Huelva, Spain
289 rdf:type schema:Organization
290 grid-institutes:grid.411142.3 schema:alternateName Dermatology Department, Hospital del Mar, Barcelona, Spain
291 schema:name Dermatology Department, Hospital del Mar, Barcelona, Spain
292 rdf:type schema:Organization
293 grid-institutes:grid.411375.5 schema:alternateName Medical Oncology Department, Hospital Universitario Virgen Macarena, Sevilla, Spain
294 schema:name Medical Oncology Department, Hospital Universitario Virgen Macarena, Sevilla, Spain
295 rdf:type schema:Organization
296 grid-institutes:grid.411730.0 schema:alternateName Dermatology Department, Clínica Universitaria de Navarra, Pamplona, Spain
297 Medical Oncology Department, Clínica Universitaria de Navarra, Pamplona, Spain
298 schema:name Dermatology Department, Clínica Universitaria de Navarra, Pamplona, Spain
299 Medical Oncology Department, Clínica Universitaria de Navarra, Pamplona, Spain
300 rdf:type schema:Organization
301 grid-institutes:grid.413396.a schema:alternateName Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
302 schema:name Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
303 rdf:type schema:Organization
304 grid-institutes:grid.418082.7 schema:alternateName Dermatology Department, Instituto Valenciano de Oncología, Valencia, Spain
305 schema:name Dermatology Department, Instituto Valenciano de Oncología, Valencia, Spain
306 rdf:type schema:Organization
307 grid-institutes:grid.476458.c schema:alternateName Dermatology Service, Instituto de Investigación Sanitaria La Fe, Valencia, Spain
308 schema:name Dermatology Service, Instituto de Investigación Sanitaria La Fe, Valencia, Spain
309 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...