Comprehensive overview of the efficacy and safety of sorafenib in advanced or metastatic renal cell carcinoma after a first tyrosine ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-06

AUTHORS

F. J. Afonso, U. Anido, O. Fernández-Calvo, S. Vázquez-Estévez, L. León, M. Lázaro, M. Ramos, L. Antón-Aparicio

ABSTRACT

We performed a literature search that shed light on the signaling pathways involved in the sorafenib activity as first- or subsequent-line treatment, taking into account its toxicity profile. Sorafenib appears to have better tolerability when compared with other agents in the same indication. Cross-resistance between tyrosine kinase inhibitors (TKIs) may be limited, even after failure with a previous VEGFR inhibitor, but the optimal sequence with TKIs remains to be determined. Randomized trials of second-line treatment options have showed either modest or no differences in terms of progression-free and overall survival (OS). Direct comparison between sorafenib and axitinib demonstrated differences in terms of PFS in favor of axitinib, but not in terms of OS as second-line treatment. In contrast, a phase III study showed a benefit in OS, favoring sorafenib when compared with temsirolimus. In conclusion, after using other VEGF inhibitor such as sunitinib, sorafenib is active and safe for the treatment of patients with advanced or metastatic RCC. More... »

PAGES

425-433

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12094-012-0985-x

DOI

http://dx.doi.org/10.1007/s12094-012-0985-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029456658

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23401018


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoma, Renal Cell", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Clinical Trials as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Niacinamide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenylurea Compounds", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Kinase Inhibitors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein-Tyrosine Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Salvage Therapy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Rate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Treatment Outcome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Hospital Architect Marcide-Novoa Santos", 
          "id": "https://www.grid.ac/institutes/grid.414353.4", 
          "name": [
            "Complexo Hospitalario Arquitecto Marcide, Ferrol, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Afonso", 
        "givenName": "F. J.", 
        "id": "sg:person.01300162376.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300162376.84"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Complejo Hospitalario Universitario de Santiago", 
          "id": "https://www.grid.ac/institutes/grid.411048.8", 
          "name": [
            "Complexo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Anido", 
        "givenName": "U.", 
        "id": "sg:person.01277421642.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277421642.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Complejo Hospitalario de Ourense", 
          "id": "https://www.grid.ac/institutes/grid.418883.e", 
          "name": [
            "Complexo Hospitalario Universitario de Ourense, Ourense, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fern\u00e1ndez-Calvo", 
        "givenName": "O.", 
        "id": "sg:person.01320574663.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01320574663.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Lucus Augusti", 
          "id": "https://www.grid.ac/institutes/grid.414792.d", 
          "name": [
            "Hospital Universitario Lucus August\u00ed, Lugo, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "V\u00e1zquez-Est\u00e9vez", 
        "givenName": "S.", 
        "id": "sg:person.01136233063.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01136233063.18"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Complejo Hospitalario Universitario de Santiago", 
          "id": "https://www.grid.ac/institutes/grid.411048.8", 
          "name": [
            "Complexo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Le\u00f3n", 
        "givenName": "L.", 
        "id": "sg:person.0642670634.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642670634.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Hospital Complex Of Vigo", 
          "id": "https://www.grid.ac/institutes/grid.411855.c", 
          "name": [
            "Complexo Hospitalario Universitario, Vigo, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "L\u00e1zaro", 
        "givenName": "M.", 
        "id": "sg:person.0657157106.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657157106.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Centro Oncol\u00f3gico de Galica, A Coru\u00f1a, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ramos", 
        "givenName": "M.", 
        "id": "sg:person.0773766447.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773766447.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Complexo Hospitalario Universitario A Coru\u00f1a", 
          "id": "https://www.grid.ac/institutes/grid.411066.4", 
          "name": [
            "Medical Oncology Service, Complexo Hospitalario Universitario A Coru\u00f1a, 84 As Xubias, 15006, A Coru\u00f1a, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ant\u00f3n-Aparicio", 
        "givenName": "L.", 
        "id": "sg:person.0741370133.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741370133.39"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.juro.2009.02.119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001110310"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1677/erc.0.0080219", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001327260"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1677/erc.0.0080219", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001327260"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1464-410x.2011.10186.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007095954"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa065044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007947936"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.24864", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008293686"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.24864", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008293686"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-60393-8_16", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010664330", 
          "https://doi.org/10.1007/978-3-642-60393-8_16"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-010-9815-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011210343", 
          "https://doi.org/10.1007/s12032-010-9815-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.20.1293", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013684571"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-04-1443", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014291431"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1569-9056(09)60263-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015403594"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.25219", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017587632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.25219", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017587632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc905", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017804909", 
          "https://doi.org/10.1038/nrc905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc905", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017804909", 
          "https://doi.org/10.1038/nrc905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.19.5511", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017988502"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ju.0000074870.54671.98", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018970576"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ju.0000074870.54671.98", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018970576"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.25327", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020612015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdq651", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020627241"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejca.2011.11.027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021703405"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature00766", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023536940", 
          "https://doi.org/10.1038/nature00766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature00766", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023536940", 
          "https://doi.org/10.1038/nature00766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1464-410x.2008.08336.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024136119"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-009-9303-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025096513", 
          "https://doi.org/10.1007/s12032-009-9303-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-009-9303-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025096513", 
          "https://doi.org/10.1007/s12032-009-9303-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa060655", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025111240"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdi310", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028006302"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdi310", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028006302"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.critrevonc.2010.03.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028447413"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.24009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028569352"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000151394", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032092032"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.bi.62.070193.004223", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033190023"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.eururo.2008.10.027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038646010"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-04-2658", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040669587"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/418934a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042017236", 
          "https://doi.org/10.1038/418934a"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/418934a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042017236", 
          "https://doi.org/10.1038/418934a"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/emboj/20.14.3716", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042020186"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-011-0048-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043402694", 
          "https://doi.org/10.1007/s12032-011-0048-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-011-0048-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043402694", 
          "https://doi.org/10.1007/s12032-011-0048-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044819609", 
          "https://doi.org/10.1038/nrc1097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc1097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044819609", 
          "https://doi.org/10.1038/nrc1097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(08)61039-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045744105"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.urology.2009.12.031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047906141"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2005.06.124", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048258031"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(11)61613-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052713041"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/1381612023393026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069164607"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5414/cpp47061", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072835567"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076011518", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079010052", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.26.15_suppl.9603", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079373629"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2012.30.5_suppl.354", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083399160"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2012.30.5_suppl.387", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083399434"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2011.29.15_suppl.4609", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083947986"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-06", 
    "datePublishedReg": "2013-06-01", 
    "description": "We performed a literature search that shed light on the signaling pathways involved in the sorafenib activity as first- or subsequent-line treatment, taking into account its toxicity profile. Sorafenib appears to have better tolerability when compared with other agents in the same indication. Cross-resistance between tyrosine kinase inhibitors (TKIs) may be limited, even after failure with a previous VEGFR inhibitor, but the optimal sequence with TKIs remains to be determined. Randomized trials of second-line treatment options have showed either modest or no differences in terms of progression-free and overall survival (OS). Direct comparison between sorafenib and axitinib demonstrated differences in terms of PFS in favor of axitinib, but not in terms of OS as second-line treatment. In contrast, a phase III study showed a benefit in OS, favoring sorafenib when compared with temsirolimus. In conclusion, after using other VEGF inhibitor such as sunitinib, sorafenib is active and safe for the treatment of patients with advanced or metastatic RCC.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s12094-012-0985-x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1035367", 
        "issn": [
          "1699-048X", 
          "1699-3055"
        ], 
        "name": "Clinical and Translational Oncology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "15"
      }
    ], 
    "name": "Comprehensive overview of the efficacy and safety of sorafenib in advanced or metastatic renal cell carcinoma after a first tyrosine kinase inhibitor", 
    "pagination": "425-433", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "8c5394a0a33ea459de588a16df5410aac8cafbc04fe2b885d65591b2a28d9ca1"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "23401018"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101247119"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12094-012-0985-x"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1029456658"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12094-012-0985-x", 
      "https://app.dimensions.ai/details/publication/pub.1029456658"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T01:09", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000522.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs12094-012-0985-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12094-012-0985-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12094-012-0985-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12094-012-0985-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12094-012-0985-x'


 

This table displays all metadata directly associated to this object as RDF triples.

317 TRIPLES      21 PREDICATES      84 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12094-012-0985-x schema:about N28af8aca844e43d293bc28c832acb9ae
2 N34606ac5d84449ed91f6394d1a8745b0
3 N70fa2165bde7426fa35cbe9942afbb73
4 N72a4b0c00aa24e4880229c84ac78021e
5 N7a13e90703494338b6561d2c480a8fae
6 N85202417010c46b79005c9d997d2e1ba
7 N894abdc5c9654118a4300faec28adf8b
8 N95f039741b484e0d9b16ef6707eb03b7
9 Nc0709f302c964cc28abaac5a20b8d635
10 Ne8841f6a08d84bf8a07e2db631e2e402
11 Nf8517b1d18c345b798bd38be0d8fa272
12 anzsrc-for:11
13 anzsrc-for:1112
14 schema:author Na6f2f53f231d48d4b821dd5d67f78dda
15 schema:citation sg:pub.10.1007/978-3-642-60393-8_16
16 sg:pub.10.1007/s12032-009-9303-z
17 sg:pub.10.1007/s12032-010-9815-6
18 sg:pub.10.1007/s12032-011-0048-0
19 sg:pub.10.1038/418934a
20 sg:pub.10.1038/nature00766
21 sg:pub.10.1038/nrc1097
22 sg:pub.10.1038/nrc905
23 https://app.dimensions.ai/details/publication/pub.1076011518
24 https://app.dimensions.ai/details/publication/pub.1079010052
25 https://doi.org/10.1002/cncr.24009
26 https://doi.org/10.1002/cncr.24864
27 https://doi.org/10.1002/cncr.25219
28 https://doi.org/10.1002/cncr.25327
29 https://doi.org/10.1016/j.critrevonc.2010.03.006
30 https://doi.org/10.1016/j.ejca.2011.11.027
31 https://doi.org/10.1016/j.eururo.2008.10.027
32 https://doi.org/10.1016/j.juro.2009.02.119
33 https://doi.org/10.1016/j.urology.2009.12.031
34 https://doi.org/10.1016/s0140-6736(08)61039-9
35 https://doi.org/10.1016/s0140-6736(11)61613-9
36 https://doi.org/10.1016/s1569-9056(09)60263-3
37 https://doi.org/10.1056/nejmoa060655
38 https://doi.org/10.1056/nejmoa065044
39 https://doi.org/10.1093/annonc/mdi310
40 https://doi.org/10.1093/annonc/mdq651
41 https://doi.org/10.1093/emboj/20.14.3716
42 https://doi.org/10.1097/01.ju.0000074870.54671.98
43 https://doi.org/10.1111/j.1464-410x.2008.08336.x
44 https://doi.org/10.1111/j.1464-410x.2011.10186.x
45 https://doi.org/10.1146/annurev.bi.62.070193.004223
46 https://doi.org/10.1158/0008-5472.can-04-1443
47 https://doi.org/10.1158/1078-0432.ccr-04-2658
48 https://doi.org/10.1159/000151394
49 https://doi.org/10.1200/jco.2005.06.124
50 https://doi.org/10.1200/jco.2008.19.5511
51 https://doi.org/10.1200/jco.2008.20.1293
52 https://doi.org/10.1200/jco.2008.26.15_suppl.9603
53 https://doi.org/10.1200/jco.2011.29.15_suppl.4609
54 https://doi.org/10.1200/jco.2012.30.5_suppl.354
55 https://doi.org/10.1200/jco.2012.30.5_suppl.387
56 https://doi.org/10.1677/erc.0.0080219
57 https://doi.org/10.2174/1381612023393026
58 https://doi.org/10.5414/cpp47061
59 schema:datePublished 2013-06
60 schema:datePublishedReg 2013-06-01
61 schema:description We performed a literature search that shed light on the signaling pathways involved in the sorafenib activity as first- or subsequent-line treatment, taking into account its toxicity profile. Sorafenib appears to have better tolerability when compared with other agents in the same indication. Cross-resistance between tyrosine kinase inhibitors (TKIs) may be limited, even after failure with a previous VEGFR inhibitor, but the optimal sequence with TKIs remains to be determined. Randomized trials of second-line treatment options have showed either modest or no differences in terms of progression-free and overall survival (OS). Direct comparison between sorafenib and axitinib demonstrated differences in terms of PFS in favor of axitinib, but not in terms of OS as second-line treatment. In contrast, a phase III study showed a benefit in OS, favoring sorafenib when compared with temsirolimus. In conclusion, after using other VEGF inhibitor such as sunitinib, sorafenib is active and safe for the treatment of patients with advanced or metastatic RCC.
62 schema:genre research_article
63 schema:inLanguage en
64 schema:isAccessibleForFree false
65 schema:isPartOf N55883138173446cd8d0e7108882beb94
66 Nd7ca8fd46ad54e7abd6b39b377b667cb
67 sg:journal.1035367
68 schema:name Comprehensive overview of the efficacy and safety of sorafenib in advanced or metastatic renal cell carcinoma after a first tyrosine kinase inhibitor
69 schema:pagination 425-433
70 schema:productId N3b17cafa4f77442a8bc7a2afe5fb45b5
71 N429d6bb3ef8d48e9b8956bbf96fba681
72 N57322cdaef57434d9b486a2ee5ff737b
73 N739c40c248114422aa77ac82baf3c9ac
74 Na895fcc3fc2d4959a19e2debf1b27f7c
75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029456658
76 https://doi.org/10.1007/s12094-012-0985-x
77 schema:sdDatePublished 2019-04-11T01:09
78 schema:sdLicense https://scigraph.springernature.com/explorer/license/
79 schema:sdPublisher N1a6b4ed7a0864c7fa727be7952ef1e77
80 schema:url http://link.springer.com/10.1007%2Fs12094-012-0985-x
81 sgo:license sg:explorer/license/
82 sgo:sdDataset articles
83 rdf:type schema:ScholarlyArticle
84 N0c1a8ae499c547fb9015529ad66bdfbf rdf:first sg:person.0773766447.05
85 rdf:rest Nfc60799c47524d729e8abfa9afc5ac46
86 N1a6b4ed7a0864c7fa727be7952ef1e77 schema:name Springer Nature - SN SciGraph project
87 rdf:type schema:Organization
88 N28af8aca844e43d293bc28c832acb9ae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Carcinoma, Renal Cell
90 rdf:type schema:DefinedTerm
91 N2fac97c8d82548f594801edf0cdde9d9 rdf:first sg:person.0657157106.25
92 rdf:rest N0c1a8ae499c547fb9015529ad66bdfbf
93 N34606ac5d84449ed91f6394d1a8745b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Survival Rate
95 rdf:type schema:DefinedTerm
96 N3b17cafa4f77442a8bc7a2afe5fb45b5 schema:name readcube_id
97 schema:value 8c5394a0a33ea459de588a16df5410aac8cafbc04fe2b885d65591b2a28d9ca1
98 rdf:type schema:PropertyValue
99 N429d6bb3ef8d48e9b8956bbf96fba681 schema:name dimensions_id
100 schema:value pub.1029456658
101 rdf:type schema:PropertyValue
102 N55883138173446cd8d0e7108882beb94 schema:issueNumber 6
103 rdf:type schema:PublicationIssue
104 N57322cdaef57434d9b486a2ee5ff737b schema:name nlm_unique_id
105 schema:value 101247119
106 rdf:type schema:PropertyValue
107 N5b5bac84585d4a0b85402ae50f7a7d6d rdf:first sg:person.01320574663.54
108 rdf:rest N6d7c2cd910f84638b28ae1422348c539
109 N6d7c2cd910f84638b28ae1422348c539 rdf:first sg:person.01136233063.18
110 rdf:rest N90b19c36995247818d0779afde3abfc1
111 N70fa2165bde7426fa35cbe9942afbb73 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Salvage Therapy
113 rdf:type schema:DefinedTerm
114 N72a4b0c00aa24e4880229c84ac78021e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Protein-Tyrosine Kinases
116 rdf:type schema:DefinedTerm
117 N739c40c248114422aa77ac82baf3c9ac schema:name doi
118 schema:value 10.1007/s12094-012-0985-x
119 rdf:type schema:PropertyValue
120 N7a13e90703494338b6561d2c480a8fae schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Protein Kinase Inhibitors
122 rdf:type schema:DefinedTerm
123 N85202417010c46b79005c9d997d2e1ba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Clinical Trials as Topic
125 rdf:type schema:DefinedTerm
126 N894abdc5c9654118a4300faec28adf8b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Treatment Outcome
128 rdf:type schema:DefinedTerm
129 N90b19c36995247818d0779afde3abfc1 rdf:first sg:person.0642670634.99
130 rdf:rest N2fac97c8d82548f594801edf0cdde9d9
131 N90d2a2f42efc4fd98b07aa63618ed672 schema:name Centro Oncológico de Galica, A Coruña, Spain
132 rdf:type schema:Organization
133 N95f039741b484e0d9b16ef6707eb03b7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Niacinamide
135 rdf:type schema:DefinedTerm
136 Na6f2f53f231d48d4b821dd5d67f78dda rdf:first sg:person.01300162376.84
137 rdf:rest Nbfb9824857724cc5b62bf856f70a27bb
138 Na895fcc3fc2d4959a19e2debf1b27f7c schema:name pubmed_id
139 schema:value 23401018
140 rdf:type schema:PropertyValue
141 Nbfb9824857724cc5b62bf856f70a27bb rdf:first sg:person.01277421642.37
142 rdf:rest N5b5bac84585d4a0b85402ae50f7a7d6d
143 Nc0709f302c964cc28abaac5a20b8d635 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Humans
145 rdf:type schema:DefinedTerm
146 Nd7ca8fd46ad54e7abd6b39b377b667cb schema:volumeNumber 15
147 rdf:type schema:PublicationVolume
148 Ne8841f6a08d84bf8a07e2db631e2e402 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Phenylurea Compounds
150 rdf:type schema:DefinedTerm
151 Nf8517b1d18c345b798bd38be0d8fa272 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Kidney Neoplasms
153 rdf:type schema:DefinedTerm
154 Nfc60799c47524d729e8abfa9afc5ac46 rdf:first sg:person.0741370133.39
155 rdf:rest rdf:nil
156 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
157 schema:name Medical and Health Sciences
158 rdf:type schema:DefinedTerm
159 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
160 schema:name Oncology and Carcinogenesis
161 rdf:type schema:DefinedTerm
162 sg:journal.1035367 schema:issn 1699-048X
163 1699-3055
164 schema:name Clinical and Translational Oncology
165 rdf:type schema:Periodical
166 sg:person.01136233063.18 schema:affiliation https://www.grid.ac/institutes/grid.414792.d
167 schema:familyName Vázquez-Estévez
168 schema:givenName S.
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01136233063.18
170 rdf:type schema:Person
171 sg:person.01277421642.37 schema:affiliation https://www.grid.ac/institutes/grid.411048.8
172 schema:familyName Anido
173 schema:givenName U.
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277421642.37
175 rdf:type schema:Person
176 sg:person.01300162376.84 schema:affiliation https://www.grid.ac/institutes/grid.414353.4
177 schema:familyName Afonso
178 schema:givenName F. J.
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300162376.84
180 rdf:type schema:Person
181 sg:person.01320574663.54 schema:affiliation https://www.grid.ac/institutes/grid.418883.e
182 schema:familyName Fernández-Calvo
183 schema:givenName O.
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01320574663.54
185 rdf:type schema:Person
186 sg:person.0642670634.99 schema:affiliation https://www.grid.ac/institutes/grid.411048.8
187 schema:familyName León
188 schema:givenName L.
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642670634.99
190 rdf:type schema:Person
191 sg:person.0657157106.25 schema:affiliation https://www.grid.ac/institutes/grid.411855.c
192 schema:familyName Lázaro
193 schema:givenName M.
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0657157106.25
195 rdf:type schema:Person
196 sg:person.0741370133.39 schema:affiliation https://www.grid.ac/institutes/grid.411066.4
197 schema:familyName Antón-Aparicio
198 schema:givenName L.
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741370133.39
200 rdf:type schema:Person
201 sg:person.0773766447.05 schema:affiliation N90d2a2f42efc4fd98b07aa63618ed672
202 schema:familyName Ramos
203 schema:givenName M.
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773766447.05
205 rdf:type schema:Person
206 sg:pub.10.1007/978-3-642-60393-8_16 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010664330
207 https://doi.org/10.1007/978-3-642-60393-8_16
208 rdf:type schema:CreativeWork
209 sg:pub.10.1007/s12032-009-9303-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1025096513
210 https://doi.org/10.1007/s12032-009-9303-z
211 rdf:type schema:CreativeWork
212 sg:pub.10.1007/s12032-010-9815-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011210343
213 https://doi.org/10.1007/s12032-010-9815-6
214 rdf:type schema:CreativeWork
215 sg:pub.10.1007/s12032-011-0048-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043402694
216 https://doi.org/10.1007/s12032-011-0048-0
217 rdf:type schema:CreativeWork
218 sg:pub.10.1038/418934a schema:sameAs https://app.dimensions.ai/details/publication/pub.1042017236
219 https://doi.org/10.1038/418934a
220 rdf:type schema:CreativeWork
221 sg:pub.10.1038/nature00766 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023536940
222 https://doi.org/10.1038/nature00766
223 rdf:type schema:CreativeWork
224 sg:pub.10.1038/nrc1097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044819609
225 https://doi.org/10.1038/nrc1097
226 rdf:type schema:CreativeWork
227 sg:pub.10.1038/nrc905 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017804909
228 https://doi.org/10.1038/nrc905
229 rdf:type schema:CreativeWork
230 https://app.dimensions.ai/details/publication/pub.1076011518 schema:CreativeWork
231 https://app.dimensions.ai/details/publication/pub.1079010052 schema:CreativeWork
232 https://doi.org/10.1002/cncr.24009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028569352
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1002/cncr.24864 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008293686
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1002/cncr.25219 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017587632
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1002/cncr.25327 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020612015
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/j.critrevonc.2010.03.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028447413
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1016/j.ejca.2011.11.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021703405
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1016/j.eururo.2008.10.027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038646010
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1016/j.juro.2009.02.119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001110310
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1016/j.urology.2009.12.031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047906141
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1016/s0140-6736(08)61039-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045744105
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1016/s0140-6736(11)61613-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052713041
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1016/s1569-9056(09)60263-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015403594
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1056/nejmoa060655 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025111240
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1056/nejmoa065044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007947936
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1093/annonc/mdi310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028006302
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1093/annonc/mdq651 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020627241
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1093/emboj/20.14.3716 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042020186
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1097/01.ju.0000074870.54671.98 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018970576
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1111/j.1464-410x.2008.08336.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024136119
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1111/j.1464-410x.2011.10186.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1007095954
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1146/annurev.bi.62.070193.004223 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033190023
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1158/0008-5472.can-04-1443 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014291431
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1158/1078-0432.ccr-04-2658 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040669587
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1159/000151394 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032092032
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1200/jco.2005.06.124 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048258031
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1200/jco.2008.19.5511 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017988502
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1200/jco.2008.20.1293 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013684571
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1200/jco.2008.26.15_suppl.9603 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079373629
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1200/jco.2011.29.15_suppl.4609 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083947986
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1200/jco.2012.30.5_suppl.354 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083399160
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1200/jco.2012.30.5_suppl.387 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083399434
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1677/erc.0.0080219 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001327260
295 rdf:type schema:CreativeWork
296 https://doi.org/10.2174/1381612023393026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069164607
297 rdf:type schema:CreativeWork
298 https://doi.org/10.5414/cpp47061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072835567
299 rdf:type schema:CreativeWork
300 https://www.grid.ac/institutes/grid.411048.8 schema:alternateName Complejo Hospitalario Universitario de Santiago
301 schema:name Complexo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain
302 rdf:type schema:Organization
303 https://www.grid.ac/institutes/grid.411066.4 schema:alternateName Complexo Hospitalario Universitario A Coruña
304 schema:name Medical Oncology Service, Complexo Hospitalario Universitario A Coruña, 84 As Xubias, 15006, A Coruña, Spain
305 rdf:type schema:Organization
306 https://www.grid.ac/institutes/grid.411855.c schema:alternateName University Hospital Complex Of Vigo
307 schema:name Complexo Hospitalario Universitario, Vigo, Spain
308 rdf:type schema:Organization
309 https://www.grid.ac/institutes/grid.414353.4 schema:alternateName Hospital Architect Marcide-Novoa Santos
310 schema:name Complexo Hospitalario Arquitecto Marcide, Ferrol, Spain
311 rdf:type schema:Organization
312 https://www.grid.ac/institutes/grid.414792.d schema:alternateName Hospital Universitario Lucus Augusti
313 schema:name Hospital Universitario Lucus Augustí, Lugo, Spain
314 rdf:type schema:Organization
315 https://www.grid.ac/institutes/grid.418883.e schema:alternateName Complejo Hospitalario de Ourense
316 schema:name Complexo Hospitalario Universitario de Ourense, Ourense, Spain
317 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...