Evaluation of toxicity of surgery and/or chemoirradiation treatment of uterine cervix cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-02

AUTHORS

Vicente Tormo Ferrero, Francisco J. Andreu Martínez, Rafael Cardenal Maciá

ABSTRACT

OBJECTIVE: To evaluate acute and chronic toxicity of chemoirradiation treatment (neoadjuvant, adjuvant and radical treatment) in patients diagnosed with cervix cancer. METHODS: From December 1999 to August 2007, 53 patients diagnosed with adenocarcinoma or squamous cell carcinoma of the uterine cervix received neoadjuvant, adjuvant or radical chemoirradiation. RESULTS: Acute gastrointestinal toxicity of grade 3 or more in 9 patients (17%) and haematological toxicity of grade 3 or more in 9 patients (17%). Chronic toxicity of grade 3 or more was shown in only 2 patients (4%). The most frequent toxicities were gastrointestinal toxicity and haematological toxicity. The most frequent chronic toxicities were gastrointestinal toxicity and vaginal toxicity. CONCLUSIONS: We report that the combined neoadjuvant, adjuvant or radical chemoirradiation treatment with weekly cisplatin chemotherapy (40 mg/m(2)/week) in patients diagnosed with cervix cancer is a well tolerated treatment and chronic and acute toxicity is low-grade. This treatment scheme has easy compliance. More... »

PAGES

109-113

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12094-009-0323-0

DOI

http://dx.doi.org/10.1007/s12094-009-0323-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027705134

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19211377


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