Secondary effects and biochemical control in patients with early prostate cancer treated with 125-I seeds View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-06

AUTHORS

Virginia Morillo, José Luis Guinot, Isabel Tortajada, José Vicente Ricós, Leoncio Arribas, María Maroñas, Marian Estornell, Juan Casanova

ABSTRACT

OBJECTIVE: To retrospectively evaluate the toxicity of low-dose-rate brachytherapy and to relate it to the dose-volume to organs at risk. MATERIAL AND METHODS: We study 160 patients with early prostate cancer, treated with (125)-I implants. Most of them were T1c (63.1%), T2a (35.6%) and Gleason < or =6 (96.2%). Median PSA was 7.2 ng/ml (2.3-13.5); 85.6% were lowrisk cases and 14.4% high-risk cases. Mean follow-up was 24 months (7-48). RESULTS: Acute urinary toxicity related to urological quality of life (UQL=CVU) was tolerable in 75% and unsatisfactory in 25%. Urinary retention was present in 6.9%. IPSS, V100 and D90 were related to the urinary toxicity grade. Rectal toxicity (RTOG) G2 was 0.6%. Sexual potency showed no changes with regard to the basal in 69%. Actuarial biochemical control was 89.8% at four years. CONCLUSIONS: Brachytherapy with (125)-I seeds yields acceptable toxicity and excellent biochemical control. More... »

PAGES

359

References to SciGraph publications

  • 2005-08. Acute urinary morbidity following I-125 prostate brachytherapy in INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12094-008-0212-y

    DOI

    http://dx.doi.org/10.1007/s12094-008-0212-y

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1044076358

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/18558583


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    Turtle is a human-readable linked data format.

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    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12094-008-0212-y'


     

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