The MicroFlow Spacer: A Drug-Eluting Stent for the Ethmoid Sinus View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-07

AUTHORS

Peter J. Catalano, Mark Thong, Ray Weiss, Tamara Rimash

ABSTRACT

To evaluate the short-term outcomes and safety of a newly introduced drug-eluting ethmoid stent. Prospective study of 23 patients with a total of 40 implanted ethmoid sinuses. Two tertiary care medical facility. Twenty-three patients with medically refractory chronic rhinosinusitis were treated with patient-appropriate endoscopic sinus surgery, with the modification of treating the ethmoid sinuses with an ethmoid stent infused with triamcinolone, instead of conventional endoscopic ethmoidectomy. Patients were then followed up over 6 months. Outcomes were assessed by interval changes in 20-item Sino-Nasal Outcome Test (SNOT-20) and Lund-MacKay CT scores. Safety was determined by adverse events. Overall, the pre-op SNOT-20 mean score was 2.18, versus post-op score of 1.02, an improvement of 1.16 that was both statistically (P < 0.001) and clinically significant. Ethmoid-specific and side-specific Lund-MacKay mean scores both also showed statistically significant improvements. Pre-op ethmoid-specific Lund-MacKay mean score was 1.93, versus post-op score of 1.10, an improvement of 0.83 (P < 0.001). Pre-op side-specific Lund-MacKay mean score was 5.75, compared with post-op score of 2.95, an improvement of 2.80 (P < 0.001). There were no significant intra-op or post-op complications encountered. This triamcinolone-infused ethmoid stent appears safe and effective in treating chronic ethmoid sinus disease within the defined follow-up period. The ability to deliver medication directly to diseased mucosa holds wide-ranging potential. More... »

PAGES

279-284

References to SciGraph publications

  • 2008-05. Balloon sinuplasty: a current hot topic in rhinology in EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s12070-011-0258-y

    DOI

    http://dx.doi.org/10.1007/s12070-011-0258-y

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22754810


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