Polysulphone composite membranes modified with two types of carbon additives as a potential material for bone tissue regeneration View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-02

AUTHORS

ALICJA WEDEL-GRZENDA, ANETA FRACZEK-SZCZYPTA, MAURICIO TERRONES, ANA LAURA ELÍAS, MALGORZATA LEKKA, ELZBIETA MENASZEK, STANISLAW BLAZEWICZ

ABSTRACT

This study presents a detailed evaluation of the impact of carbon fibrous materials on the physicochemical properties of polysulphone (PSU) membranes and their preliminary osteoblast-like cells response in vitro. Multi-walled carbon nanotubes (MWCNTs) and short carbon fibres (SCFs) were incorporated into PSU and membranes were produced by the phase inversion method. Then, the physicochemical properties of the membranes’ surface were investigated. Scanning electron microscopy (SEM) was used to evaluate microstructure and porosity. Surface properties such as roughness, wettability and surface energy were evaluated using atomic force microscopy (AFM), contact profilometry and a goniometer, respectively. The presence of carbon fibrous additives in the PSU matrix improved its hydrophilicity. Porosity and topography of the PSU membranes were also changed upon incorporation of carbon additives. The mechanical properties of the PSU membranes were improved after SCF addition. All physicochemical properties of the obtained composite membranes had significant impact on the osteoblast-like cells response. Preliminary viability tests indicated biocompatibility of all membranes. More... »

PAGES

201-212

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12034-017-1360-x

DOI

http://dx.doi.org/10.1007/s12034-017-1360-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1083698682


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269 schema:name The Pennsylvania State University, Department of Physics and Center for 2-Dimensional and Layered Materials, 104 Davey Laboratory, 16802, University Park, PA, USA
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271 https://www.grid.ac/institutes/grid.418860.3 schema:alternateName Institute of Nuclear Physics Polish Academy of Sciences
272 schema:name The Henryk Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences; Department of Experimental Physics of Complex Systems, Laboratory of Biophysical Microstructures, Radzikowskiego 52, 31-342, Krakow, Poland
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274 https://www.grid.ac/institutes/grid.5522.0 schema:alternateName Jagiellonian University
275 schema:name Collegium Medicum, Jagiellonian University, Faculty of Pharmacy, Department of Cytobiology, Medyczna 9, 30-068, Krakow, Poland
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277 https://www.grid.ac/institutes/grid.9922.0 schema:alternateName AGH University of Science and Technology
278 schema:name AGH-University of Science and Technology, Faculty of Materials Science and Ceramics, Department of Biomaterials, Al. Mickiewicza 30, 30-059, Krakow, Poland
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