High Serum Levels of Caspase-3 and Early Mortality in Patients with Severe Spontaneous Intracerebral Hemorrhage View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2020-06-09

AUTHORS

Leonardo Lorente, María M. Martín, Antonia Pérez-Cejas, Agustín F. González-Rivero, Rafael Sabatel, Luis Ramos, Mónica Argueso, Jordi Solé-Violán, Juan J. Cáceres, Alejandro Jiménez, Victor García-Marín

ABSTRACT

BackgroundApoptotic cell death leads to secondary brain injury after spontaneous intracerebral hemorrhage (SIH). There is an association between serum caspase-3 levels and late mortality (at 6 months) in patients with SIH in basal ganglia. The new objective of this study was to determine whether there exists an association between serum caspase-3 levels and early mortality (at 30 days) in patients with SIH at different sites and not only in basal ganglia.MethodsPatients with severe supratentorial SIH (defined as Glasgow Coma Scale < 9) admitted in 6 Spanish hospitals were included in this observational and prospective study. Patients with SIH due to aneurysm, arteriovenous malformation, and anticoagulant or fibrinolytic treatment were excluded. Serum caspase-3 levels at days 1, 4, and 8 of SIH were determined. Thirty-day mortality was the end-point study.ResultsNon-surviving (n = 53) showed higher serum caspase-3 levels at days 1 (p < 0.001), 4 (p < 0.001), and 8 (p < 0.001) than survivor patients (n = 64). Multiple logistic regression analysis showed an association of serum caspase-3 levels > 0.167 ng/mL with 30-day mortality (Odds Ratio = 47.007; 95% CI = 4.838–456.727; p = 0.001).ConclusionsThe new findings of our study are that serum caspase-3 levels are associated with early mortality in patients with severe supratentorial SIH at different sites and that those levels during the first week of SIH are higher in non-survivors than in survivors. More... »

PAGES

175-181

Journal

TITLE

Neurocritical Care

ISSUE

1

VOLUME

34

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12028-020-01012-3

DOI

http://dx.doi.org/10.1007/s12028-020-01012-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1128303852

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/32514709


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Brain Injuries", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Caspase 3", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cerebral Hemorrhage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glasgow Coma Scale", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prospective Studies", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Intensive Care Unit, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411220.4", 
          "name": [
            "Intensive Care Unit, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lorente", 
        "givenName": "Leonardo", 
        "id": "sg:person.01100400223.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100400223.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Intensive Care Unit, Hospital Universitario Nuestra Se\u00f1ora de Candelaria, Crta del Rosario s/n, 38010, Santa Cruz de Tenerife, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411331.5", 
          "name": [
            "Intensive Care Unit, Hospital Universitario Nuestra Se\u00f1ora de Candelaria, Crta del Rosario s/n, 38010, Santa Cruz de Tenerife, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mart\u00edn", 
        "givenName": "Mar\u00eda M.", 
        "id": "sg:person.0647470200.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647470200.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratory Department, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411220.4", 
          "name": [
            "Laboratory Department, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "P\u00e9rez-Cejas", 
        "givenName": "Antonia", 
        "id": "sg:person.01167111602.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167111602.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Laboratory Department, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411220.4", 
          "name": [
            "Laboratory Department, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gonz\u00e1lez-Rivero", 
        "givenName": "Agust\u00edn F.", 
        "id": "sg:person.01111531022.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111531022.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Radiology, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411220.4", 
          "name": [
            "Department of Radiology, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sabatel", 
        "givenName": "Rafael", 
        "id": "sg:person.011754274164.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011754274164.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Intensive Care Unit, Hospital General La Palma, Buenavista de Arriba s/n, 38713, Bre\u00f1a Alta, La Palma, Spain", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Intensive Care Unit, Hospital General La Palma, Buenavista de Arriba s/n, 38713, Bre\u00f1a Alta, La Palma, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ramos", 
        "givenName": "Luis", 
        "id": "sg:person.0737347050.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737347050.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Intensive Care Unit, Hospital Cl\u00ednico Universitario de Valencia, Avda. Blasco Ib\u00e1\u00f1ez no 17-19, 46004, Valencia, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411308.f", 
          "name": [
            "Intensive Care Unit, Hospital Cl\u00ednico Universitario de Valencia, Avda. Blasco Ib\u00e1\u00f1ez no 17-19, 46004, Valencia, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Argueso", 
        "givenName": "M\u00f3nica", 
        "id": "sg:person.01034773124.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034773124.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Intensive Care Unit, Hospital Universitario Dr. Negr\u00edn, CIBERES, Barranco de la Ballena s/n, 35010, Las Palmas de Gran Canaria, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411250.3", 
          "name": [
            "Intensive Care Unit, Hospital Universitario Dr. Negr\u00edn, CIBERES, Barranco de la Ballena s/n, 35010, Las Palmas de Gran Canaria, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sol\u00e9-Viol\u00e1n", 
        "givenName": "Jordi", 
        "id": "sg:person.01142573341.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142573341.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Intensive Care Unit, Hospital Insular, Plaza Dr. Pasteur s/n, 35016, Las Palmas de Gran Canaria, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411322.7", 
          "name": [
            "Intensive Care Unit, Hospital Insular, Plaza Dr. Pasteur s/n, 35016, Las Palmas de Gran Canaria, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "C\u00e1ceres", 
        "givenName": "Juan J.", 
        "id": "sg:person.01053575450.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053575450.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Research Unit, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411220.4", 
          "name": [
            "Research Unit, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jim\u00e9nez", 
        "givenName": "Alejandro", 
        "id": "sg:person.01025307027.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025307027.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Neurosurgery, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain", 
          "id": "http://www.grid.ac/institutes/grid.411220.4", 
          "name": [
            "Department of Neurosurgery, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Garc\u00eda-Mar\u00edn", 
        "givenName": "Victor", 
        "id": "sg:person.01052414032.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052414032.53"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s11064-017-2322-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090300467", 
          "https://doi.org/10.1007/s11064-017-2322-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12883-015-0485-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043034092", 
          "https://doi.org/10.1186/s12883-015-0485-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12028-019-00739-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1115024272", 
          "https://doi.org/10.1007/s12028-019-00739-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12883-018-1127-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106369956", 
          "https://doi.org/10.1186/s12883-018-1127-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02861871", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042026061", 
          "https://doi.org/10.1007/bf02861871"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00701-006-0887-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051543669", 
          "https://doi.org/10.1007/s00701-006-0887-1"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2020-06-09", 
    "datePublishedReg": "2020-06-09", 
    "description": "BackgroundApoptotic cell death leads to secondary brain injury after spontaneous intracerebral hemorrhage (SIH). There is an association between serum caspase-3 levels and late mortality (at 6 months) in patients with SIH in basal ganglia. The new objective of this study was to determine whether there exists an association between serum caspase-3 levels and early mortality (at 30\u00a0days) in patients with SIH at different sites and not only in basal ganglia.MethodsPatients with severe supratentorial SIH (defined as Glasgow Coma Scale <\u20099) admitted in 6 Spanish hospitals were included in this observational and prospective study. Patients with SIH due to aneurysm, arteriovenous malformation, and anticoagulant or fibrinolytic treatment were excluded. Serum caspase-3 levels at days 1, 4, and 8 of SIH were determined. Thirty-day mortality was the end-point study.ResultsNon-surviving (n\u2009=\u200953) showed higher serum caspase-3 levels at days 1 (p\u2009<\u20090.001), 4 (p\u2009<\u20090.001), and 8 (p\u2009<\u20090.001) than survivor patients (n\u2009=\u200964). Multiple logistic regression analysis showed an association of serum caspase-3 levels >\u20090.167\u00a0ng/mL with 30-day mortality (Odds Ratio\u2009=\u200947.007; 95% CI\u2009=\u20094.838\u2013456.727; p\u2009=\u20090.001).ConclusionsThe new findings of our study are that serum caspase-3 levels are associated with early mortality in patients with severe supratentorial SIH at different sites and that those levels during the first week of SIH are higher in non-survivors than in survivors.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s12028-020-01012-3", 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.9667523", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1031461", 
        "issn": [
          "1541-6933", 
          "1556-0961"
        ], 
        "name": "Neurocritical Care", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "34"
      }
    ], 
    "keywords": [
      "serum caspase-3 levels", 
      "spontaneous intracerebral hemorrhage", 
      "caspase-3 levels", 
      "supratentorial spontaneous intracerebral hemorrhage", 
      "early mortality", 
      "intracerebral hemorrhage", 
      "basal ganglia", 
      "day 1", 
      "severe spontaneous intracerebral hemorrhage", 
      "multiple logistic regression analysis", 
      "Thirty-day mortality", 
      "secondary brain injury", 
      "higher serum levels", 
      "logistic regression analysis", 
      "end-point study", 
      "late mortality", 
      "fibrinolytic treatment", 
      "serum levels", 
      "prospective study", 
      "brain injury", 
      "Spanish hospitals", 
      "arteriovenous malformations", 
      "patients", 
      "mortality", 
      "first week", 
      "caspase-3", 
      "hemorrhage", 
      "regression analysis", 
      "ganglia", 
      "cell death", 
      "association", 
      "MethodsPatients", 
      "levels", 
      "aneurysms", 
      "hospital", 
      "injury", 
      "malformations", 
      "new findings", 
      "study", 
      "different sites", 
      "survivors", 
      "weeks", 
      "death", 
      "treatment", 
      "findings", 
      "sites", 
      "objective", 
      "analysis", 
      "new objectives"
    ], 
    "name": "High Serum Levels of Caspase-3 and Early Mortality in Patients with Severe Spontaneous Intracerebral Hemorrhage", 
    "pagination": "175-181", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1128303852"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12028-020-01012-3"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "32514709"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12028-020-01012-3", 
      "https://app.dimensions.ai/details/publication/pub.1128303852"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-11-24T21:06", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221124/entities/gbq_results/article/article_844.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s12028-020-01012-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12028-020-01012-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12028-020-01012-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12028-020-01012-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12028-020-01012-3'


 

This table displays all metadata directly associated to this object as RDF triples.

253 TRIPLES      21 PREDICATES      86 URIs      72 LITERALS      13 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12028-020-01012-3 schema:about N10f9dac4ff564be1accd16f8df04dc87
2 N4632e1e754a64fa29e5b48461d8f7f7c
3 N5db3945e421f4d8e9ae66c4524033ae9
4 N72cbfb63e7654735969797d5c11b477c
5 N85d3c795535b43829c77a9a9b7340bd9
6 Ndc6e87d07d03419a828c87af8b6ff28c
7 anzsrc-for:11
8 anzsrc-for:1103
9 schema:author N6d06fe0a37e84b1b8b5b661534dd9fff
10 schema:citation sg:pub.10.1007/bf02861871
11 sg:pub.10.1007/s00701-006-0887-1
12 sg:pub.10.1007/s11064-017-2322-9
13 sg:pub.10.1007/s12028-019-00739-y
14 sg:pub.10.1186/s12883-015-0485-z
15 sg:pub.10.1186/s12883-018-1127-z
16 schema:datePublished 2020-06-09
17 schema:datePublishedReg 2020-06-09
18 schema:description BackgroundApoptotic cell death leads to secondary brain injury after spontaneous intracerebral hemorrhage (SIH). There is an association between serum caspase-3 levels and late mortality (at 6 months) in patients with SIH in basal ganglia. The new objective of this study was to determine whether there exists an association between serum caspase-3 levels and early mortality (at 30 days) in patients with SIH at different sites and not only in basal ganglia.MethodsPatients with severe supratentorial SIH (defined as Glasgow Coma Scale < 9) admitted in 6 Spanish hospitals were included in this observational and prospective study. Patients with SIH due to aneurysm, arteriovenous malformation, and anticoagulant or fibrinolytic treatment were excluded. Serum caspase-3 levels at days 1, 4, and 8 of SIH were determined. Thirty-day mortality was the end-point study.ResultsNon-surviving (n = 53) showed higher serum caspase-3 levels at days 1 (p < 0.001), 4 (p < 0.001), and 8 (p < 0.001) than survivor patients (n = 64). Multiple logistic regression analysis showed an association of serum caspase-3 levels > 0.167 ng/mL with 30-day mortality (Odds Ratio = 47.007; 95% CI = 4.838–456.727; p = 0.001).ConclusionsThe new findings of our study are that serum caspase-3 levels are associated with early mortality in patients with severe supratentorial SIH at different sites and that those levels during the first week of SIH are higher in non-survivors than in survivors.
19 schema:genre article
20 schema:isAccessibleForFree false
21 schema:isPartOf N60c345d3bce949e0b27518b71b3f7da5
22 N706dd9cbe4334e20a992bf2c1dc9a2b4
23 sg:journal.1031461
24 schema:keywords MethodsPatients
25 Spanish hospitals
26 Thirty-day mortality
27 analysis
28 aneurysms
29 arteriovenous malformations
30 association
31 basal ganglia
32 brain injury
33 caspase-3
34 caspase-3 levels
35 cell death
36 day 1
37 death
38 different sites
39 early mortality
40 end-point study
41 fibrinolytic treatment
42 findings
43 first week
44 ganglia
45 hemorrhage
46 higher serum levels
47 hospital
48 injury
49 intracerebral hemorrhage
50 late mortality
51 levels
52 logistic regression analysis
53 malformations
54 mortality
55 multiple logistic regression analysis
56 new findings
57 new objectives
58 objective
59 patients
60 prospective study
61 regression analysis
62 secondary brain injury
63 serum caspase-3 levels
64 serum levels
65 severe spontaneous intracerebral hemorrhage
66 sites
67 spontaneous intracerebral hemorrhage
68 study
69 supratentorial spontaneous intracerebral hemorrhage
70 survivors
71 treatment
72 weeks
73 schema:name High Serum Levels of Caspase-3 and Early Mortality in Patients with Severe Spontaneous Intracerebral Hemorrhage
74 schema:pagination 175-181
75 schema:productId N98a649e1816c4f84b219453bb0f7d937
76 Nc9acd4ac4a9744e8a167b6de6528a81b
77 Nf50e860511c34730b3125a0d0edeff3a
78 schema:sameAs https://app.dimensions.ai/details/publication/pub.1128303852
79 https://doi.org/10.1007/s12028-020-01012-3
80 schema:sdDatePublished 2022-11-24T21:06
81 schema:sdLicense https://scigraph.springernature.com/explorer/license/
82 schema:sdPublisher Nb6fda4e0ac24401483164acb2c8556d8
83 schema:url https://doi.org/10.1007/s12028-020-01012-3
84 sgo:license sg:explorer/license/
85 sgo:sdDataset articles
86 rdf:type schema:ScholarlyArticle
87 N0124723af64444a1b0dd2f3a9c2ca6f0 rdf:first sg:person.0737347050.04
88 rdf:rest Nea5139750e1c42baa78ef5d2c820494a
89 N08d7399be4cb436d94bb537ab2953a7a rdf:first sg:person.01111531022.04
90 rdf:rest Ncfbb5cf3b7874cdcb4bd0578a442b6e9
91 N10f9dac4ff564be1accd16f8df04dc87 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Glasgow Coma Scale
93 rdf:type schema:DefinedTerm
94 N278d704053f24ad691afc312d6f966d9 rdf:first sg:person.01142573341.81
95 rdf:rest N290544e56511446c9e4832c24a20c08f
96 N290544e56511446c9e4832c24a20c08f rdf:first sg:person.01053575450.28
97 rdf:rest N6b1b1e8be38d42be99b998286108483f
98 N4632e1e754a64fa29e5b48461d8f7f7c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Caspase 3
100 rdf:type schema:DefinedTerm
101 N5db3945e421f4d8e9ae66c4524033ae9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Humans
103 rdf:type schema:DefinedTerm
104 N5dfa1ee1634c4e4b8cf920a7ef7ef247 rdf:first sg:person.0647470200.43
105 rdf:rest Ndc6646e154d34889b59d896458b58c0f
106 N60c345d3bce949e0b27518b71b3f7da5 schema:volumeNumber 34
107 rdf:type schema:PublicationVolume
108 N6b1b1e8be38d42be99b998286108483f rdf:first sg:person.01025307027.11
109 rdf:rest N96681fd0fbc8454b9e020e9df075404e
110 N6d06fe0a37e84b1b8b5b661534dd9fff rdf:first sg:person.01100400223.37
111 rdf:rest N5dfa1ee1634c4e4b8cf920a7ef7ef247
112 N706dd9cbe4334e20a992bf2c1dc9a2b4 schema:issueNumber 1
113 rdf:type schema:PublicationIssue
114 N72cbfb63e7654735969797d5c11b477c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Cerebral Hemorrhage
116 rdf:type schema:DefinedTerm
117 N85d3c795535b43829c77a9a9b7340bd9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Prospective Studies
119 rdf:type schema:DefinedTerm
120 N96681fd0fbc8454b9e020e9df075404e rdf:first sg:person.01052414032.53
121 rdf:rest rdf:nil
122 N98a649e1816c4f84b219453bb0f7d937 schema:name dimensions_id
123 schema:value pub.1128303852
124 rdf:type schema:PropertyValue
125 Nb6fda4e0ac24401483164acb2c8556d8 schema:name Springer Nature - SN SciGraph project
126 rdf:type schema:Organization
127 Nc9acd4ac4a9744e8a167b6de6528a81b schema:name pubmed_id
128 schema:value 32514709
129 rdf:type schema:PropertyValue
130 Ncfbb5cf3b7874cdcb4bd0578a442b6e9 rdf:first sg:person.011754274164.04
131 rdf:rest N0124723af64444a1b0dd2f3a9c2ca6f0
132 Ndc6646e154d34889b59d896458b58c0f rdf:first sg:person.01167111602.44
133 rdf:rest N08d7399be4cb436d94bb537ab2953a7a
134 Ndc6e87d07d03419a828c87af8b6ff28c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Brain Injuries
136 rdf:type schema:DefinedTerm
137 Nea5139750e1c42baa78ef5d2c820494a rdf:first sg:person.01034773124.17
138 rdf:rest N278d704053f24ad691afc312d6f966d9
139 Nf50e860511c34730b3125a0d0edeff3a schema:name doi
140 schema:value 10.1007/s12028-020-01012-3
141 rdf:type schema:PropertyValue
142 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
143 schema:name Medical and Health Sciences
144 rdf:type schema:DefinedTerm
145 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
146 schema:name Clinical Sciences
147 rdf:type schema:DefinedTerm
148 sg:grant.9667523 http://pending.schema.org/fundedItem sg:pub.10.1007/s12028-020-01012-3
149 rdf:type schema:MonetaryGrant
150 sg:journal.1031461 schema:issn 1541-6933
151 1556-0961
152 schema:name Neurocritical Care
153 schema:publisher Springer Nature
154 rdf:type schema:Periodical
155 sg:person.01025307027.11 schema:affiliation grid-institutes:grid.411220.4
156 schema:familyName Jiménez
157 schema:givenName Alejandro
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025307027.11
159 rdf:type schema:Person
160 sg:person.01034773124.17 schema:affiliation grid-institutes:grid.411308.f
161 schema:familyName Argueso
162 schema:givenName Mónica
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034773124.17
164 rdf:type schema:Person
165 sg:person.01052414032.53 schema:affiliation grid-institutes:grid.411220.4
166 schema:familyName García-Marín
167 schema:givenName Victor
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052414032.53
169 rdf:type schema:Person
170 sg:person.01053575450.28 schema:affiliation grid-institutes:grid.411322.7
171 schema:familyName Cáceres
172 schema:givenName Juan J.
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053575450.28
174 rdf:type schema:Person
175 sg:person.01100400223.37 schema:affiliation grid-institutes:grid.411220.4
176 schema:familyName Lorente
177 schema:givenName Leonardo
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100400223.37
179 rdf:type schema:Person
180 sg:person.01111531022.04 schema:affiliation grid-institutes:grid.411220.4
181 schema:familyName González-Rivero
182 schema:givenName Agustín F.
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111531022.04
184 rdf:type schema:Person
185 sg:person.01142573341.81 schema:affiliation grid-institutes:grid.411250.3
186 schema:familyName Solé-Violán
187 schema:givenName Jordi
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142573341.81
189 rdf:type schema:Person
190 sg:person.01167111602.44 schema:affiliation grid-institutes:grid.411220.4
191 schema:familyName Pérez-Cejas
192 schema:givenName Antonia
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167111602.44
194 rdf:type schema:Person
195 sg:person.011754274164.04 schema:affiliation grid-institutes:grid.411220.4
196 schema:familyName Sabatel
197 schema:givenName Rafael
198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011754274164.04
199 rdf:type schema:Person
200 sg:person.0647470200.43 schema:affiliation grid-institutes:grid.411331.5
201 schema:familyName Martín
202 schema:givenName María M.
203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647470200.43
204 rdf:type schema:Person
205 sg:person.0737347050.04 schema:affiliation grid-institutes:None
206 schema:familyName Ramos
207 schema:givenName Luis
208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737347050.04
209 rdf:type schema:Person
210 sg:pub.10.1007/bf02861871 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042026061
211 https://doi.org/10.1007/bf02861871
212 rdf:type schema:CreativeWork
213 sg:pub.10.1007/s00701-006-0887-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051543669
214 https://doi.org/10.1007/s00701-006-0887-1
215 rdf:type schema:CreativeWork
216 sg:pub.10.1007/s11064-017-2322-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090300467
217 https://doi.org/10.1007/s11064-017-2322-9
218 rdf:type schema:CreativeWork
219 sg:pub.10.1007/s12028-019-00739-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1115024272
220 https://doi.org/10.1007/s12028-019-00739-y
221 rdf:type schema:CreativeWork
222 sg:pub.10.1186/s12883-015-0485-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1043034092
223 https://doi.org/10.1186/s12883-015-0485-z
224 rdf:type schema:CreativeWork
225 sg:pub.10.1186/s12883-018-1127-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1106369956
226 https://doi.org/10.1186/s12883-018-1127-z
227 rdf:type schema:CreativeWork
228 grid-institutes:None schema:alternateName Intensive Care Unit, Hospital General La Palma, Buenavista de Arriba s/n, 38713, Breña Alta, La Palma, Spain
229 schema:name Intensive Care Unit, Hospital General La Palma, Buenavista de Arriba s/n, 38713, Breña Alta, La Palma, Spain
230 rdf:type schema:Organization
231 grid-institutes:grid.411220.4 schema:alternateName Department of Neurosurgery, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain
232 Department of Radiology, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain
233 Intensive Care Unit, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain
234 Laboratory Department, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain
235 Research Unit, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain
236 schema:name Department of Neurosurgery, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain
237 Department of Radiology, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain
238 Intensive Care Unit, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain
239 Laboratory Department, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain
240 Research Unit, Hospital Universitario de Canarias, Ofra s/n, La Laguna, 38320, Santa Cruz de Tenerife, Spain
241 rdf:type schema:Organization
242 grid-institutes:grid.411250.3 schema:alternateName Intensive Care Unit, Hospital Universitario Dr. Negrín, CIBERES, Barranco de la Ballena s/n, 35010, Las Palmas de Gran Canaria, Spain
243 schema:name Intensive Care Unit, Hospital Universitario Dr. Negrín, CIBERES, Barranco de la Ballena s/n, 35010, Las Palmas de Gran Canaria, Spain
244 rdf:type schema:Organization
245 grid-institutes:grid.411308.f schema:alternateName Intensive Care Unit, Hospital Clínico Universitario de Valencia, Avda. Blasco Ibáñez no 17-19, 46004, Valencia, Spain
246 schema:name Intensive Care Unit, Hospital Clínico Universitario de Valencia, Avda. Blasco Ibáñez no 17-19, 46004, Valencia, Spain
247 rdf:type schema:Organization
248 grid-institutes:grid.411322.7 schema:alternateName Intensive Care Unit, Hospital Insular, Plaza Dr. Pasteur s/n, 35016, Las Palmas de Gran Canaria, Spain
249 schema:name Intensive Care Unit, Hospital Insular, Plaza Dr. Pasteur s/n, 35016, Las Palmas de Gran Canaria, Spain
250 rdf:type schema:Organization
251 grid-institutes:grid.411331.5 schema:alternateName Intensive Care Unit, Hospital Universitario Nuestra Señora de Candelaria, Crta del Rosario s/n, 38010, Santa Cruz de Tenerife, Spain
252 schema:name Intensive Care Unit, Hospital Universitario Nuestra Señora de Candelaria, Crta del Rosario s/n, 38010, Santa Cruz de Tenerife, Spain
253 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...