Management of Hyponatremia and Volume Contraction View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-07-12

AUTHORS

Alejandro A. Rabinstein, Nicolas Bruder

ABSTRACT

Hyponatremia is the most common electrolyte imbalance seen in patients with aneurysmal subarachnoid hemorrhage, occurring in one-third to one-half of patients. Hyponatremia may be caused by cerebral salt wasting and by the syndrome of inappropriate secretion of antidiuretic hormone or a combination of both. Limited data are available describing hyponatremia treatment in subarachnoid hemorrhage patients. A Medline search was performed for English-language manuscripts describing original research in the treatment for hyponatremia in patients with aneurysmal subarachnoid hemorrhage. Seven appropriate articles were identified as followed: three testing fludrocortisone, two hydrocortisone, and one each for hypertonic saline and 5% albumin. Data quality for treatment efficacy and safety were moderate for corticosteroid studies and low or very low for hypertonic saline and 5% albumin. Available data, although limited, support early treatment with corticosteroids to limit hyponatremia, with fludrocortisone causing fewer side effects. More... »

PAGES

354

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12028-011-9585-9

DOI

http://dx.doi.org/10.1007/s12028-011-9585-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011788064

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21748503


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