Neuroendocrine Liver Metastasis—a Specific Set of Markers to Detect Primary Tumor Sites View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2018-11-19

AUTHORS

Andreas Selberherr, Oskar Koperek, Philipp Riss, Christian Scheuba, Reto Kaderli, Aurel Perren, Bruno Niederle

ABSTRACT

The diagnosis of neuroendocrine neoplasia (NEN) is often made at an advanced stage of disease, including hepatic metastasis. At this point, the primary may still be unknown and sometimes cannot even be detected by functional imaging, especially in very small tumors of the pancreas (pan) and small intestinal (si) entities. The site of the primary may be based on biopsy specimens of the liver applying a specific set of markers. Specimens of liver metastases from 87 patients with NENs were studied. In retrospect, 50 patients had si and 37 pan NENs. Tissue samples were evaluated by immunohistochemistry. The markers applied were insulin gene enhancer protein Islet-1 (ISL-1), homeobox protein CDX-2 (CDX2), thyroid transcription factor 1 (TTF-1), and serotonin. Positive stains for CDX2 were documented in 43 (86%) and for serotonin in 45 (90%) of 50 siNENs. Three panNENs were positive for CDX2 and one for serotonin, respectively. ISL-1 was negative throughout in siNENs and also negative in 8 of 50 panNENs (21.6%). TTF-1 was negative in more than 90% of the specimens of either entity. Immunohistochemical markers in liver metastasis can lead the way to the site of the primary NEN. They should always be used in combined clusters. More... »

PAGES

31-34

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s12022-018-9558-z

DOI

http://dx.doi.org/10.1007/s12022-018-9558-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1110028242

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30456697


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers, Tumor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "CDX2 Transcription Factor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunohistochemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "LIM-Homeodomain Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liver Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neuroendocrine Tumors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Serotonin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thyroid Nuclear Factor 1", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Section \u201cEndocrine Surgery\u201d, Division of General Surgery, Department of Surgery, Medical University Vienna, W\u00e4hringer G\u00fcrtel 18-20, 1090, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.22937.3d", 
          "name": [
            "Section \u201cEndocrine Surgery\u201d, Division of General Surgery, Department of Surgery, Medical University Vienna, W\u00e4hringer G\u00fcrtel 18-20, 1090, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Selberherr", 
        "givenName": "Andreas", 
        "id": "sg:person.01365255052.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365255052.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Pathology, Medical University, W\u00e4hringer G\u00fcrtel 18-20, 1090, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Department of Pathology, Medical University, W\u00e4hringer G\u00fcrtel 18-20, 1090, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Koperek", 
        "givenName": "Oskar", 
        "id": "sg:person.0637444237.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637444237.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section \u201cEndocrine Surgery\u201d, Division of General Surgery, Department of Surgery, Medical University Vienna, W\u00e4hringer G\u00fcrtel 18-20, 1090, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.22937.3d", 
          "name": [
            "Section \u201cEndocrine Surgery\u201d, Division of General Surgery, Department of Surgery, Medical University Vienna, W\u00e4hringer G\u00fcrtel 18-20, 1090, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Riss", 
        "givenName": "Philipp", 
        "id": "sg:person.01107211310.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01107211310.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section \u201cEndocrine Surgery\u201d, Division of General Surgery, Department of Surgery, Medical University Vienna, W\u00e4hringer G\u00fcrtel 18-20, 1090, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.22937.3d", 
          "name": [
            "Section \u201cEndocrine Surgery\u201d, Division of General Surgery, Department of Surgery, Medical University Vienna, W\u00e4hringer G\u00fcrtel 18-20, 1090, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Scheuba", 
        "givenName": "Christian", 
        "id": "sg:person.0617351314.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617351314.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section \u201cEndocrine Surgery\u201d, Division of General Surgery, Department of Surgery, Medical University Vienna, W\u00e4hringer G\u00fcrtel 18-20, 1090, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.22937.3d", 
          "name": [
            "Section \u201cEndocrine Surgery\u201d, Division of General Surgery, Department of Surgery, Medical University Vienna, W\u00e4hringer G\u00fcrtel 18-20, 1090, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kaderli", 
        "givenName": "Reto", 
        "id": "sg:person.01327210221.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01327210221.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Pathology, University of Bern, Murtenstrasse 31, 3012, Bern, Switzerland", 
          "id": "http://www.grid.ac/institutes/grid.5734.5", 
          "name": [
            "Institute of Pathology, University of Bern, Murtenstrasse 31, 3012, Bern, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Perren", 
        "givenName": "Aurel", 
        "id": "sg:person.0660235001.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660235001.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Section \u201cEndocrine Surgery\u201d, Division of General Surgery, Department of Surgery, Medical University Vienna, W\u00e4hringer G\u00fcrtel 18-20, 1090, Vienna, Austria", 
          "id": "http://www.grid.ac/institutes/grid.22937.3d", 
          "name": [
            "Section \u201cEndocrine Surgery\u201d, Division of General Surgery, Department of Surgery, Medical University Vienna, W\u00e4hringer G\u00fcrtel 18-20, 1090, Vienna, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Niederle", 
        "givenName": "Bruno", 
        "id": "sg:person.0671724636.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671724636.94"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s12022-013-9264-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051456436", 
          "https://doi.org/10.1007/s12022-013-9264-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/modpathol.2013.40", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029669666", 
          "https://doi.org/10.1038/modpathol.2013.40"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s40364-018-0129-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103471898", 
          "https://doi.org/10.1186/s40364-018-0129-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00428-006-0250-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017988295", 
          "https://doi.org/10.1007/s00428-006-0250-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00428-007-0461-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007268859", 
          "https://doi.org/10.1007/s00428-007-0461-0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-11-19", 
    "datePublishedReg": "2018-11-19", 
    "description": "The diagnosis of neuroendocrine neoplasia (NEN) is often made at an advanced stage of disease, including hepatic metastasis. At this point, the primary may still be unknown and sometimes cannot even be detected by functional imaging, especially in very small tumors of the pancreas (pan) and small intestinal (si) entities. The site of the primary may be based on biopsy specimens of the liver applying a specific set of markers. Specimens of liver metastases from 87 patients with NENs were studied. In retrospect, 50 patients had si and 37 pan NENs. Tissue samples were evaluated by immunohistochemistry. The markers applied were insulin gene enhancer protein Islet-1 (ISL-1), homeobox protein CDX-2 (CDX2), thyroid transcription factor 1 (TTF-1), and serotonin. Positive stains for CDX2 were documented in 43 (86%) and for serotonin in 45 (90%) of 50 siNENs. Three panNENs were positive for CDX2 and one for serotonin, respectively. ISL-1 was negative throughout in siNENs and also negative in 8 of 50 panNENs (21.6%). TTF-1 was negative in more than 90% of the specimens of either entity. Immunohistochemical markers in liver metastasis can lead the way to the site of the primary NEN. They should always be used in combined clusters.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s12022-018-9558-z", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1100468", 
        "issn": [
          "1046-3976", 
          "1559-0097"
        ], 
        "name": "Endocrine Pathology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "30"
      }
    ], 
    "keywords": [
      "neuroendocrine neoplasia", 
      "liver metastases", 
      "CDX-2", 
      "neuroendocrine liver metastases", 
      "thyroid transcription factor-1", 
      "primary tumor site", 
      "hepatic metastases", 
      "transcription factor 1", 
      "biopsy specimens", 
      "small tumors", 
      "immunohistochemical markers", 
      "advanced stage", 
      "TTF-1", 
      "tumor site", 
      "metastasis", 
      "positive stain", 
      "functional imaging", 
      "serotonin", 
      "Islet-1", 
      "tissue samples", 
      "factor 1", 
      "negative throughout", 
      "patients", 
      "markers", 
      "PanNENs", 
      "primary", 
      "neoplasia", 
      "immunohistochemistry", 
      "tumors", 
      "pancreas", 
      "disease", 
      "liver", 
      "diagnosis", 
      "specimens", 
      "entities", 
      "stain", 
      "imaging", 
      "sites", 
      "specific set", 
      "throughout", 
      "stage", 
      "retrospect", 
      "samples", 
      "combined clusters", 
      "point", 
      "clusters", 
      "way", 
      "set"
    ], 
    "name": "Neuroendocrine Liver Metastasis\u2014a Specific Set of Markers to Detect Primary Tumor Sites", 
    "pagination": "31-34", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1110028242"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s12022-018-9558-z"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30456697"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s12022-018-9558-z", 
      "https://app.dimensions.ai/details/publication/pub.1110028242"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-10T10:19", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_791.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s12022-018-9558-z"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s12022-018-9558-z'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s12022-018-9558-z'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s12022-018-9558-z'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s12022-018-9558-z'


 

This table displays all metadata directly associated to this object as RDF triples.

242 TRIPLES      22 PREDICATES      95 URIs      82 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s12022-018-9558-z schema:about N0db37bdfce064f09bd8ea231638ee5f8
2 N2555af97fede44a9abdeb571458dc379
3 N3ad2592d92344e08a84112d9ce428871
4 N3ea4cb1d72464259bc1e6719f5bd81ea
5 N4048c7c4f1d74f54a23cde548f4fc618
6 N6216b2762b324ee7aa5b5226eef757a9
7 N6220c245eef44f8f96fa6a9b598a7139
8 N70247ee81f134c2fa88043b8bec5c964
9 Nae98df29b11a4813b17de07eb7529863
10 Nb8886efc975446758b2a336100f95a4c
11 Nbc5f76f180584b46a923518e3ab34573
12 Ne075c241b12744dbbe656962e6259df2
13 Ne9dc4d351a5c408bb9c36506fec553e9
14 Nf01937d1c54e44ffadbff7963214d937
15 Nf1720be70f3c4555936c622bd3f717fc
16 Nfb159f76a22c4d9e8c1a3b598f348ab9
17 anzsrc-for:11
18 anzsrc-for:1103
19 schema:author N727e63ee26ed4fdf839b3dbf2ba7fcf7
20 schema:citation sg:pub.10.1007/s00428-006-0250-1
21 sg:pub.10.1007/s00428-007-0461-0
22 sg:pub.10.1007/s12022-013-9264-9
23 sg:pub.10.1038/modpathol.2013.40
24 sg:pub.10.1186/s40364-018-0129-8
25 schema:datePublished 2018-11-19
26 schema:datePublishedReg 2018-11-19
27 schema:description The diagnosis of neuroendocrine neoplasia (NEN) is often made at an advanced stage of disease, including hepatic metastasis. At this point, the primary may still be unknown and sometimes cannot even be detected by functional imaging, especially in very small tumors of the pancreas (pan) and small intestinal (si) entities. The site of the primary may be based on biopsy specimens of the liver applying a specific set of markers. Specimens of liver metastases from 87 patients with NENs were studied. In retrospect, 50 patients had si and 37 pan NENs. Tissue samples were evaluated by immunohistochemistry. The markers applied were insulin gene enhancer protein Islet-1 (ISL-1), homeobox protein CDX-2 (CDX2), thyroid transcription factor 1 (TTF-1), and serotonin. Positive stains for CDX2 were documented in 43 (86%) and for serotonin in 45 (90%) of 50 siNENs. Three panNENs were positive for CDX2 and one for serotonin, respectively. ISL-1 was negative throughout in siNENs and also negative in 8 of 50 panNENs (21.6%). TTF-1 was negative in more than 90% of the specimens of either entity. Immunohistochemical markers in liver metastasis can lead the way to the site of the primary NEN. They should always be used in combined clusters.
28 schema:genre article
29 schema:inLanguage en
30 schema:isAccessibleForFree true
31 schema:isPartOf N0afb21f04b444d4d8713cbcfeb7fc10f
32 N40e13e91cdf94c39b2e56153b17c14fa
33 sg:journal.1100468
34 schema:keywords CDX-2
35 Islet-1
36 PanNENs
37 TTF-1
38 advanced stage
39 biopsy specimens
40 clusters
41 combined clusters
42 diagnosis
43 disease
44 entities
45 factor 1
46 functional imaging
47 hepatic metastases
48 imaging
49 immunohistochemical markers
50 immunohistochemistry
51 liver
52 liver metastases
53 markers
54 metastasis
55 negative throughout
56 neoplasia
57 neuroendocrine liver metastases
58 neuroendocrine neoplasia
59 pancreas
60 patients
61 point
62 positive stain
63 primary
64 primary tumor site
65 retrospect
66 samples
67 serotonin
68 set
69 sites
70 small tumors
71 specific set
72 specimens
73 stage
74 stain
75 throughout
76 thyroid transcription factor-1
77 tissue samples
78 transcription factor 1
79 tumor site
80 tumors
81 way
82 schema:name Neuroendocrine Liver Metastasis—a Specific Set of Markers to Detect Primary Tumor Sites
83 schema:pagination 31-34
84 schema:productId N90aa4296674145dd838fed06d3acc5c1
85 Na242cee50d0c4746b12a3c0aa8b92d48
86 Nd2188106dc1d415db455c2d3350e2d98
87 schema:sameAs https://app.dimensions.ai/details/publication/pub.1110028242
88 https://doi.org/10.1007/s12022-018-9558-z
89 schema:sdDatePublished 2022-05-10T10:19
90 schema:sdLicense https://scigraph.springernature.com/explorer/license/
91 schema:sdPublisher N0b76a09a8c124eb3ad1b2ecd2762b3bc
92 schema:url https://doi.org/10.1007/s12022-018-9558-z
93 sgo:license sg:explorer/license/
94 sgo:sdDataset articles
95 rdf:type schema:ScholarlyArticle
96 N0afb21f04b444d4d8713cbcfeb7fc10f schema:issueNumber 1
97 rdf:type schema:PublicationIssue
98 N0b76a09a8c124eb3ad1b2ecd2762b3bc schema:name Springer Nature - SN SciGraph project
99 rdf:type schema:Organization
100 N0db37bdfce064f09bd8ea231638ee5f8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name CDX2 Transcription Factor
102 rdf:type schema:DefinedTerm
103 N2555af97fede44a9abdeb571458dc379 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Immunohistochemistry
105 rdf:type schema:DefinedTerm
106 N2ae9664d42e64bddb4fcbedc00eeb3ef rdf:first sg:person.01107211310.34
107 rdf:rest N82175f1dad9a42079d2f29897e176a8f
108 N2f9f524282a14016b50c0e61de4665a8 rdf:first sg:person.01327210221.79
109 rdf:rest Ndb8026c246c845af9d8df466f7375f99
110 N3ad2592d92344e08a84112d9ce428871 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Transcription Factors
112 rdf:type schema:DefinedTerm
113 N3ea4cb1d72464259bc1e6719f5bd81ea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Biomarkers, Tumor
115 rdf:type schema:DefinedTerm
116 N4048c7c4f1d74f54a23cde548f4fc618 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Middle Aged
118 rdf:type schema:DefinedTerm
119 N40e13e91cdf94c39b2e56153b17c14fa schema:volumeNumber 30
120 rdf:type schema:PublicationVolume
121 N6216b2762b324ee7aa5b5226eef757a9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Aged
123 rdf:type schema:DefinedTerm
124 N6220c245eef44f8f96fa6a9b598a7139 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Female
126 rdf:type schema:DefinedTerm
127 N70247ee81f134c2fa88043b8bec5c964 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Humans
129 rdf:type schema:DefinedTerm
130 N727e63ee26ed4fdf839b3dbf2ba7fcf7 rdf:first sg:person.01365255052.76
131 rdf:rest N9e73924dc7494ed89078e131651f11c0
132 N82175f1dad9a42079d2f29897e176a8f rdf:first sg:person.0617351314.15
133 rdf:rest N2f9f524282a14016b50c0e61de4665a8
134 N90aa4296674145dd838fed06d3acc5c1 schema:name doi
135 schema:value 10.1007/s12022-018-9558-z
136 rdf:type schema:PropertyValue
137 N9e73924dc7494ed89078e131651f11c0 rdf:first sg:person.0637444237.30
138 rdf:rest N2ae9664d42e64bddb4fcbedc00eeb3ef
139 Na242cee50d0c4746b12a3c0aa8b92d48 schema:name pubmed_id
140 schema:value 30456697
141 rdf:type schema:PropertyValue
142 Nae98df29b11a4813b17de07eb7529863 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Thyroid Nuclear Factor 1
144 rdf:type schema:DefinedTerm
145 Nb8886efc975446758b2a336100f95a4c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name Liver Neoplasms
147 rdf:type schema:DefinedTerm
148 Nbc5f76f180584b46a923518e3ab34573 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
149 schema:name Neuroendocrine Tumors
150 rdf:type schema:DefinedTerm
151 Nd2188106dc1d415db455c2d3350e2d98 schema:name dimensions_id
152 schema:value pub.1110028242
153 rdf:type schema:PropertyValue
154 Ndb8026c246c845af9d8df466f7375f99 rdf:first sg:person.0660235001.55
155 rdf:rest Ne4223f966fc440f2ae43bf66c33ed095
156 Ne075c241b12744dbbe656962e6259df2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name LIM-Homeodomain Proteins
158 rdf:type schema:DefinedTerm
159 Ne4223f966fc440f2ae43bf66c33ed095 rdf:first sg:person.0671724636.94
160 rdf:rest rdf:nil
161 Ne9dc4d351a5c408bb9c36506fec553e9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Male
163 rdf:type schema:DefinedTerm
164 Nf01937d1c54e44ffadbff7963214d937 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Serotonin
166 rdf:type schema:DefinedTerm
167 Nf1720be70f3c4555936c622bd3f717fc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Aged, 80 and over
169 rdf:type schema:DefinedTerm
170 Nfb159f76a22c4d9e8c1a3b598f348ab9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Adult
172 rdf:type schema:DefinedTerm
173 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
174 schema:name Medical and Health Sciences
175 rdf:type schema:DefinedTerm
176 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
177 schema:name Clinical Sciences
178 rdf:type schema:DefinedTerm
179 sg:journal.1100468 schema:issn 1046-3976
180 1559-0097
181 schema:name Endocrine Pathology
182 schema:publisher Springer Nature
183 rdf:type schema:Periodical
184 sg:person.01107211310.34 schema:affiliation grid-institutes:grid.22937.3d
185 schema:familyName Riss
186 schema:givenName Philipp
187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01107211310.34
188 rdf:type schema:Person
189 sg:person.01327210221.79 schema:affiliation grid-institutes:grid.22937.3d
190 schema:familyName Kaderli
191 schema:givenName Reto
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01327210221.79
193 rdf:type schema:Person
194 sg:person.01365255052.76 schema:affiliation grid-institutes:grid.22937.3d
195 schema:familyName Selberherr
196 schema:givenName Andreas
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365255052.76
198 rdf:type schema:Person
199 sg:person.0617351314.15 schema:affiliation grid-institutes:grid.22937.3d
200 schema:familyName Scheuba
201 schema:givenName Christian
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0617351314.15
203 rdf:type schema:Person
204 sg:person.0637444237.30 schema:affiliation grid-institutes:None
205 schema:familyName Koperek
206 schema:givenName Oskar
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637444237.30
208 rdf:type schema:Person
209 sg:person.0660235001.55 schema:affiliation grid-institutes:grid.5734.5
210 schema:familyName Perren
211 schema:givenName Aurel
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660235001.55
213 rdf:type schema:Person
214 sg:person.0671724636.94 schema:affiliation grid-institutes:grid.22937.3d
215 schema:familyName Niederle
216 schema:givenName Bruno
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0671724636.94
218 rdf:type schema:Person
219 sg:pub.10.1007/s00428-006-0250-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017988295
220 https://doi.org/10.1007/s00428-006-0250-1
221 rdf:type schema:CreativeWork
222 sg:pub.10.1007/s00428-007-0461-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007268859
223 https://doi.org/10.1007/s00428-007-0461-0
224 rdf:type schema:CreativeWork
225 sg:pub.10.1007/s12022-013-9264-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051456436
226 https://doi.org/10.1007/s12022-013-9264-9
227 rdf:type schema:CreativeWork
228 sg:pub.10.1038/modpathol.2013.40 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029669666
229 https://doi.org/10.1038/modpathol.2013.40
230 rdf:type schema:CreativeWork
231 sg:pub.10.1186/s40364-018-0129-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103471898
232 https://doi.org/10.1186/s40364-018-0129-8
233 rdf:type schema:CreativeWork
234 grid-institutes:None schema:alternateName Department of Pathology, Medical University, Währinger Gürtel 18-20, 1090, Vienna, Austria
235 schema:name Department of Pathology, Medical University, Währinger Gürtel 18-20, 1090, Vienna, Austria
236 rdf:type schema:Organization
237 grid-institutes:grid.22937.3d schema:alternateName Section “Endocrine Surgery”, Division of General Surgery, Department of Surgery, Medical University Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria
238 schema:name Section “Endocrine Surgery”, Division of General Surgery, Department of Surgery, Medical University Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria
239 rdf:type schema:Organization
240 grid-institutes:grid.5734.5 schema:alternateName Institute of Pathology, University of Bern, Murtenstrasse 31, 3012, Bern, Switzerland
241 schema:name Institute of Pathology, University of Bern, Murtenstrasse 31, 3012, Bern, Switzerland
242 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...